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The map label for this gene is 209549941

Identifier: 209549941

GI number: 209549941

Start: 2418377

End: 2419633

Strand: Reverse

Name: 209549941

Synonym: Rleg2_2357

Alternate gene names: NA

Gene position: 2419633-2418377 (Counterclockwise)

Preceding gene: 209549942

Following gene: 209549938

Centisome position: 53.32

GC content: 66.59

Gene sequence:

>1257_bases
GTGAGGAGGGCCAGGCCTTTCCTGGCGCTCGCCGCAGCCGAGACATGTTCGCTTTCCGGCACGCGGCTGTCGACCATCGC
TATTCCCTGGCTGGTGTTGAGCACGACGGGCAGTCCTGTCCTGACCGGCGTGACGGCGATGGTGGAGATGCTGCCCTATG
TCGTCGCCAAGGCGCTCGGCGGGCCGCTGATCGACCGCGTCGGCGCCAAACGCATCGCCATCGTCTGCGATACCGCTTCG
GTGGTCGCGGTAGGGCTGGTGCCGCTGCTCGATTTCTTCGGCCTGCTCGGCATGCCGGTGCTGCTGCCTGTCGTCTTTGC
CATGGGCGTGCTGCGTGGGCCTTCCGACGCCGCCAAGCAGGCGATGGTTCCCGATATCGCCAGGCTGGCGAACGTGCCGC
TCGAACGGGTGACCGGCGTCGCCAGCGCCATCGAGCGGCTGGCCTCGACGGCGGGTGCGGCCGGCGCCGGTGCGCTGATC
GGCCTGATCGGCCCGGGCCAGGCGCTCCTCGTCAATGCCGCCACCTTCGCCGCCGCCGCGCTGATCGTCGCCGTCGGCAT
CCCCGAGATGCGGCGCACGCCAGGGCTATCCTGCGCCCGACCGGCCGAAAGGGCTTCCTATCTCGACGATCTCCGTGAAG
GCTGGCGCTTTCTGCGCGGCGATGCGGTGCTCGTCAGCATCGTCGTCATGGTGGCGATCACCAATCTGCTGGACCAGGCC
TATCATGCGGTGCTGCTGCCTGTCTGGACACGCGATTCCGGCCATGGTCCGGAACTGCTGGGAGCGATGTTTGCGGCATT
CGCCGGCGCATCGATTGCAGGTGCGGCGATTGCCGCAGCAATCGGCGAACGGATGCCACGGCTGATCGTCTACACCGTGG
CGTTCCTGTTGACCGGCTTTCCGCGTTTTCTCGTTGTTGCGCTGGATGCGCCGCTCGGCCTTCTCTTTACGACCCTGGCC
ATCGGAGGATTCGCCTCGGGCTTCCTCAACCCGATCCTGTCGGCGGTGATCTTCGAGCGCATCCCCAAGCCGCTGACCGG
CCGCGTCATCGCATTGAACACCGCCCTCTGCTTCGCCCTCATTCCCTTCGGCGGCCTCGTCGGCGGCGCGCTGATCAGCA
CGATCGGTCTTGCCGCGGCGCTGCTGCTCACCGGGCTTGCCTATCTCGTCGCCACTCTCTTTCCCCTTGCCCTGAAAAGT
TTCCGCGGTTTCGACAGGGCAATTGCCGATGCCGGTGCTTCCGTATCAAGGCGATGA

Upstream 100 bases:

>100_bases
AGGCGGCGTCTCGGAATTCCGACATGGTTCCTTTTTATGTCATGCTGCACGCCTTCCCCTATCCGGGCCGCCTTCCGCAT
CGCGAAGGGGAGGATGAGGC

Downstream 100 bases:

>100_bases
GCGCGCGTCCGATCTCTCATGCCCCAACGCCTCGACCATCAGATCGACGAAACGGTGGATGCGCGGTTCCAGCAGGCGCT
TGTCGGGATAGAGCGTGACG

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MRRARPFLALAAAETCSLSGTRLSTIAIPWLVLSTTGSPVLTGVTAMVEMLPYVVAKALGGPLIDRVGAKRIAIVCDTAS
VVAVGLVPLLDFFGLLGMPVLLPVVFAMGVLRGPSDAAKQAMVPDIARLANVPLERVTGVASAIERLASTAGAAGAGALI
GLIGPGQALLVNAATFAAAALIVAVGIPEMRRTPGLSCARPAERASYLDDLREGWRFLRGDAVLVSIVVMVAITNLLDQA
YHAVLLPVWTRDSGHGPELLGAMFAAFAGASIAGAAIAAAIGERMPRLIVYTVAFLLTGFPRFLVVALDAPLGLLFTTLA
IGGFASGFLNPILSAVIFERIPKPLTGRVIALNTALCFALIPFGGLVGGALISTIGLAAALLLTGLAYLVATLFPLALKS
FRGFDRAIADAGASVSRR

Sequences:

>Translated_418_residues
MRRARPFLALAAAETCSLSGTRLSTIAIPWLVLSTTGSPVLTGVTAMVEMLPYVVAKALGGPLIDRVGAKRIAIVCDTAS
VVAVGLVPLLDFFGLLGMPVLLPVVFAMGVLRGPSDAAKQAMVPDIARLANVPLERVTGVASAIERLASTAGAAGAGALI
GLIGPGQALLVNAATFAAAALIVAVGIPEMRRTPGLSCARPAERASYLDDLREGWRFLRGDAVLVSIVVMVAITNLLDQA
YHAVLLPVWTRDSGHGPELLGAMFAAFAGASIAGAAIAAAIGERMPRLIVYTVAFLLTGFPRFLVVALDAPLGLLFTTLA
IGGFASGFLNPILSAVIFERIPKPLTGRVIALNTALCFALIPFGGLVGGALISTIGLAAALLLTGLAYLVATLFPLALKS
FRGFDRAIADAGASVSRR
>Mature_418_residues
MRRARPFLALAAAETCSLSGTRLSTIAIPWLVLSTTGSPVLTGVTAMVEMLPYVVAKALGGPLIDRVGAKRIAIVCDTAS
VVAVGLVPLLDFFGLLGMPVLLPVVFAMGVLRGPSDAAKQAMVPDIARLANVPLERVTGVASAIERLASTAGAAGAGALI
GLIGPGQALLVNAATFAAAALIVAVGIPEMRRTPGLSCARPAERASYLDDLREGWRFLRGDAVLVSIVVMVAITNLLDQA
YHAVLLPVWTRDSGHGPELLGAMFAAFAGASIAGAAIAAAIGERMPRLIVYTVAFLLTGFPRFLVVALDAPLGLLFTTLA
IGGFASGFLNPILSAVIFERIPKPLTGRVIALNTALCFALIPFGGLVGGALISTIGLAAALLLTGLAYLVATLFPLALKS
FRGFDRAIADAGASVSRR

Specific function: Could be involved in tetracycline efflux [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42953; Mature: 42953

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRARPFLALAAAETCSLSGTRLSTIAIPWLVLSTTGSPVLTGVTAMVEMLPYVVAKALG
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHC
GPLIDRVGAKRIAIVCDTASVVAVGLVPLLDFFGLLGMPVLLPVVFAMGVLRGPSDAAKQ
CHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AMVPDIARLANVPLERVTGVASAIERLASTAGAAGAGALIGLIGPGQALLVNAATFAAAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCCHHHHHHHHHHHHHH
LIVAVGIPEMRRTPGLSCARPAERASYLDDLREGWRFLRGDAVLVSIVVMVAITNLLDQA
HHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
YHAVLLPVWTRDSGHGPELLGAMFAAFAGASIAGAAIAAAIGERMPRLIVYTVAFLLTGF
HHHHHEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRFLVVALDAPLGLLFTTLAIGGFASGFLNPILSAVIFERIPKPLTGRVIALNTALCFAL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
IPFGGLVGGALISTIGLAAALLLTGLAYLVATLFPLALKSFRGFDRAIADAGASVSRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRRARPFLALAAAETCSLSGTRLSTIAIPWLVLSTTGSPVLTGVTAMVEMLPYVVAKALG
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHC
GPLIDRVGAKRIAIVCDTASVVAVGLVPLLDFFGLLGMPVLLPVVFAMGVLRGPSDAAKQ
CHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AMVPDIARLANVPLERVTGVASAIERLASTAGAAGAGALIGLIGPGQALLVNAATFAAAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCCHHHHHHHHHHHHHH
LIVAVGIPEMRRTPGLSCARPAERASYLDDLREGWRFLRGDAVLVSIVVMVAITNLLDQA
HHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
YHAVLLPVWTRDSGHGPELLGAMFAAFAGASIAGAAIAAAIGERMPRLIVYTVAFLLTGF
HHHHHEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRFLVVALDAPLGLLFTTLAIGGFASGFLNPILSAVIFERIPKPLTGRVIALNTALCFAL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
IPFGGLVGGALISTIGLAAALLLTGLAYLVATLFPLALKSFRGFDRAIADAGASVSRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]