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The map label for this gene is frpC [H]

Identifier: 209549794

GI number: 209549794

Start: 2261277

End: 2264063

Strand: Direct

Name: frpC [H]

Synonym: Rleg2_2205

Alternate gene names: 209549794

Gene position: 2261277-2264063 (Clockwise)

Preceding gene: 209549793

Following gene: 209549795

Centisome position: 49.83

GC content: 59.13

Gene sequence:

>2787_bases
ATGGCCTTGAATATTCTGGATACAAACGGCGCCACAATTACCAACACCGGCGCCGAGTTCGAAGCCTACGACGTTATCCG
CTACTCTGAAGCCAATCCTTCCGGACCTGTCTCCCTCACCGTCTCCGACTCCTCCGCCGCGGACCTAGCTGACGAGTTGG
GCTCGGTATCGGCAGATGTGACCGGCTCGAGCGGCGACAACACGATCACGACCGGTGCCGGCAACGACATCCTCTCAGGC
GGCGACGGCGCGGACACACTGACCGGTGGCGCCGGCGACGACATAATCTACGGCAATGCCGGCAACGACAAATTGGTCGG
CGGTGATGGCAACGATCGAATCACCGATGGTGGTTTTGGCTTTGTGTCCGGACCTGATGGCAGCCTCCAGCCAGAAATCG
TCGACATTGACGGCGGCGACGGCGACGATTTGATAACGATTGAGAGATTCGCTCCACTGATATCGGGAACGATCGATGGC
GGTGCCGGGATCGATACGTTGCGTGCCTCGGCGCTCCGGAGCCTGACGATCAAGAACGTCGAAGTGCTTGAACTCGCCGA
TTTCCAGGTGAGCGGTTCGAGTTCACAGTTCGAAAGCTTCGACAAGATCGCCAGATCAACCGATCCGGTCTTTAATTTTG
ATCCCTCACTGATAGTGACGGATAGCGCCCACCTCGATCTTTCCGACGAACTGGGAGATCTCGGCACTCTTGTCCGCGGC
TTCTCCGGCATTGACGTCAAAACCGGCGATGGCGACGATGAGTTTGCCGGCAGCAACGTCAACGACATTTTCGACGGCAG
CGGCGGTAGCGACCTCATCAATGGCAACGACGGCGATGATAAACTGACCGGCGGCGCCGGCAACGACACCATTGATGGCG
GCGCGGGCATCGACACGGCTGCATTCACAGGCAATTTCGCTGATTACTCCTTCGCGGTCGACAATGGCAGTCGCGTCGTG
ACGAGCGTGCTGGAAGGCACGGATAGACTGACAGACGTCGAATTCGCGCGCTTTGCCGATGGCGTCTACGACTTCGCGAC
GGAAACCTTCACGGTCAACAGCACCGAGCCGGGCACCCCGCTGAATATTCTGGACACGAATGGCGCGACGATTACCAAAA
CCGGCGCTGAGTTCGAAGCCTACGACGTCATCCGCGACTCCGAAATCAATCCTCTCGTCCCGGTCAACCTGGTCATCTCG
GATTCCGGCACCGTAGACCTTTCCGACGAACTGGGCTCTGGCTCCGCCAATGTGATCGGCACGAGCGGCAACGATGTGAT
CACGACAGGCGCAGGCAACGACAATATTGCAGGCGGCGACGGCGCAGACACGCTGAACGGCGGCGCAGGATACGACAGCC
TCAATGGCGGCGTTGGCAATGACACGCTGTATGGCGGTGACGGCAATGACCACATCTCCGGCGACGTCGGGAACGACGTG
ATCAGAGGCGGTGCAGGCAACGATACGATCGACGATGGCGAGCTTTTCGGCCTAAGCCCGGAAGTCATTGACATCAATGC
GGGTGACGGCAACGATTCCATAAGCGTAGGAACATTGGCTCCGCTGAATTCCGGAACGGTTGATGGCGGCGATGGGATCG
ATACGCTGCAAGCCGCTTCGCTCCGAGGCCTGACGATCAAAAACATCGAAGTCCTTGAGACGGCAGGATGGTCGGTCGCC
GGATCGAGCGCACAGTTCGAAAGCTTCGATAAAATCGTCTGGTCGACCGATCCGTTTGGCGATTTTCGCGCCGCGGTGAC
ACTGACGGACAGCGCCCACCTCGATCTCGCCGACGAGTTGGGAGATCTAGGAGCGTTCATCGACGGCGATGCCTTCGGCA
TTGACGTCAGGACCGGCGGCGGTGACGACGAGTTCACCGGCACCGACGGCAACGACATTTTCGACGGCAGCGGCGGCAAC
GACATCCTCAATGGCAATGCCGGTGATGACAAATTGACCGGCGGCGCGGGCAACGACACCATCGATGGCGGCGCGGGCAT
CGACACGGCGCTGTTCGCAGGCAATTTCGCCGATTATTCCCTTGCGTTGAACAATGGCGATCACATCCTGACAAGTGTTG
CGGAAGGGGCGGATACGCTCACAGGCGTCGAATTCGCCCGCTTTGCCGATGGCCTTTACGACTTCGGCACGGAAACCTTC
ACGCCCAAGGGCAACGCCGCGCCGACCAATATCCAGCTTTCGAAGACCGCCCTCTCCGAGGATACGCCGATCTGGACCAC
GGTCGGGCTGCTCAGCGCCAAGGACGCCGACGGTGACGTTCTGACCTACAAGCTTCTTGACGGCGCCGACGACCATTTCC
GGATCAACGGTAACCGCATCGTCACCTCAAAGGCTTTGGACTACGAGACAGCCAAATCGCACACGATCAAGGTCGCCGTC
TCCGACGGCAAGGTCACGGTCGAAAAGGACATCACGATTAACGTCCTCGACGTCAACGAAACGCCTATCAACCAAGCGCC
GATCAAGCTGTCTTTCTCGCGCAGCTCTATCTCCGAAAACGTCGCGATCGGCACATCGGTCGGCCTTCTCTCCGCCGTCG
ATCCGGAAGGCGGCACGGTGAAGTGGCGGCTGACAGATGATGCGGACGGCATCTTCAAGCTCGTCGGCAACAAGATCCAA
ACGAAGGCTGCGATCGACTTCGAAAGCAACCACAGCCTGACCTTCACCGCCGAAGCCTATGATGCGGCCGGAAATGCCAC
CAGCCACGATTTCACGGTGGCCGTGAAGGACATCTTCGAGCCATCGTTTTCGAGCCTGCTGCACTAA

Upstream 100 bases:

>100_bases
TAGATCCCCGTGGGGTTGTCGTCGGCCGAGCCGATAAACAGTTCTTTCGGGGATTTCTCATTTTTCAGAGTAAAACGCAT
CTTTTGGGGAAGATTAAAAT

Downstream 100 bases:

>100_bases
GCGCTGATCTAACCTCAACATGATCGCTCCCAGATTCAGGGATGCGTCGCCAACCTCTTTTTTGAAAGTTTGAATATGGC
CTTGAACATTCTGGACACCA

Product: hemolysin-type calcium-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 928; Mature: 927

Protein sequence:

>928_residues
MALNILDTNGATITNTGAEFEAYDVIRYSEANPSGPVSLTVSDSSAADLADELGSVSADVTGSSGDNTITTGAGNDILSG
GDGADTLTGGAGDDIIYGNAGNDKLVGGDGNDRITDGGFGFVSGPDGSLQPEIVDIDGGDGDDLITIERFAPLISGTIDG
GAGIDTLRASALRSLTIKNVEVLELADFQVSGSSSQFESFDKIARSTDPVFNFDPSLIVTDSAHLDLSDELGDLGTLVRG
FSGIDVKTGDGDDEFAGSNVNDIFDGSGGSDLINGNDGDDKLTGGAGNDTIDGGAGIDTAAFTGNFADYSFAVDNGSRVV
TSVLEGTDRLTDVEFARFADGVYDFATETFTVNSTEPGTPLNILDTNGATITKTGAEFEAYDVIRDSEINPLVPVNLVIS
DSGTVDLSDELGSGSANVIGTSGNDVITTGAGNDNIAGGDGADTLNGGAGYDSLNGGVGNDTLYGGDGNDHISGDVGNDV
IRGGAGNDTIDDGELFGLSPEVIDINAGDGNDSISVGTLAPLNSGTVDGGDGIDTLQAASLRGLTIKNIEVLETAGWSVA
GSSAQFESFDKIVWSTDPFGDFRAAVTLTDSAHLDLADELGDLGAFIDGDAFGIDVRTGGGDDEFTGTDGNDIFDGSGGN
DILNGNAGDDKLTGGAGNDTIDGGAGIDTALFAGNFADYSLALNNGDHILTSVAEGADTLTGVEFARFADGLYDFGTETF
TPKGNAAPTNIQLSKTALSEDTPIWTTVGLLSAKDADGDVLTYKLLDGADDHFRINGNRIVTSKALDYETAKSHTIKVAV
SDGKVTVEKDITINVLDVNETPINQAPIKLSFSRSSISENVAIGTSVGLLSAVDPEGGTVKWRLTDDADGIFKLVGNKIQ
TKAAIDFESNHSLTFTAEAYDAAGNATSHDFTVAVKDIFEPSFSSLLH

Sequences:

>Translated_928_residues
MALNILDTNGATITNTGAEFEAYDVIRYSEANPSGPVSLTVSDSSAADLADELGSVSADVTGSSGDNTITTGAGNDILSG
GDGADTLTGGAGDDIIYGNAGNDKLVGGDGNDRITDGGFGFVSGPDGSLQPEIVDIDGGDGDDLITIERFAPLISGTIDG
GAGIDTLRASALRSLTIKNVEVLELADFQVSGSSSQFESFDKIARSTDPVFNFDPSLIVTDSAHLDLSDELGDLGTLVRG
FSGIDVKTGDGDDEFAGSNVNDIFDGSGGSDLINGNDGDDKLTGGAGNDTIDGGAGIDTAAFTGNFADYSFAVDNGSRVV
TSVLEGTDRLTDVEFARFADGVYDFATETFTVNSTEPGTPLNILDTNGATITKTGAEFEAYDVIRDSEINPLVPVNLVIS
DSGTVDLSDELGSGSANVIGTSGNDVITTGAGNDNIAGGDGADTLNGGAGYDSLNGGVGNDTLYGGDGNDHISGDVGNDV
IRGGAGNDTIDDGELFGLSPEVIDINAGDGNDSISVGTLAPLNSGTVDGGDGIDTLQAASLRGLTIKNIEVLETAGWSVA
GSSAQFESFDKIVWSTDPFGDFRAAVTLTDSAHLDLADELGDLGAFIDGDAFGIDVRTGGGDDEFTGTDGNDIFDGSGGN
DILNGNAGDDKLTGGAGNDTIDGGAGIDTALFAGNFADYSLALNNGDHILTSVAEGADTLTGVEFARFADGLYDFGTETF
TPKGNAAPTNIQLSKTALSEDTPIWTTVGLLSAKDADGDVLTYKLLDGADDHFRINGNRIVTSKALDYETAKSHTIKVAV
SDGKVTVEKDITINVLDVNETPINQAPIKLSFSRSSISENVAIGTSVGLLSAVDPEGGTVKWRLTDDADGIFKLVGNKIQ
TKAAIDFESNHSLTFTAEAYDAAGNATSHDFTVAVKDIFEPSFSSLLH
>Mature_927_residues
ALNILDTNGATITNTGAEFEAYDVIRYSEANPSGPVSLTVSDSSAADLADELGSVSADVTGSSGDNTITTGAGNDILSGG
DGADTLTGGAGDDIIYGNAGNDKLVGGDGNDRITDGGFGFVSGPDGSLQPEIVDIDGGDGDDLITIERFAPLISGTIDGG
AGIDTLRASALRSLTIKNVEVLELADFQVSGSSSQFESFDKIARSTDPVFNFDPSLIVTDSAHLDLSDELGDLGTLVRGF
SGIDVKTGDGDDEFAGSNVNDIFDGSGGSDLINGNDGDDKLTGGAGNDTIDGGAGIDTAAFTGNFADYSFAVDNGSRVVT
SVLEGTDRLTDVEFARFADGVYDFATETFTVNSTEPGTPLNILDTNGATITKTGAEFEAYDVIRDSEINPLVPVNLVISD
SGTVDLSDELGSGSANVIGTSGNDVITTGAGNDNIAGGDGADTLNGGAGYDSLNGGVGNDTLYGGDGNDHISGDVGNDVI
RGGAGNDTIDDGELFGLSPEVIDINAGDGNDSISVGTLAPLNSGTVDGGDGIDTLQAASLRGLTIKNIEVLETAGWSVAG
SSAQFESFDKIVWSTDPFGDFRAAVTLTDSAHLDLADELGDLGAFIDGDAFGIDVRTGGGDDEFTGTDGNDIFDGSGGND
ILNGNAGDDKLTGGAGNDTIDGGAGIDTALFAGNFADYSLALNNGDHILTSVAEGADTLTGVEFARFADGLYDFGTETFT
PKGNAAPTNIQLSKTALSEDTPIWTTVGLLSAKDADGDVLTYKLLDGADDHFRINGNRIVTSKALDYETAKSHTIKVAVS
DGKVTVEKDITINVLDVNETPINQAPIKLSFSRSSISENVAIGTSVGLLSAVDPEGGTVKWRLTDDADGIFKLVGNKIQT
KAAIDFESNHSLTFTAEAYDAAGNATSHDFTVAVKDIFEPSFSSLLH

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 22 hemolysin-type calcium-binding repeats [H]

Homologues:

Organism=Drosophila melanogaster, GI281363131, Length=231, Percent_Identity=31.6017316017316, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221330158, Length=231, Percent_Identity=31.6017316017316, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 94785; Mature: 94653

Theoretical pI: Translated: 3.65; Mature: 3.65

Prosite motif: PS00486 DNA_MISMATCH_REPAIR_2 ; PS50268 CADHERIN_2 ; PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.1 %Met     (Translated Protein)
0.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNILDTNGATITNTGAEFEAYDVIRYSEANPSGPVSLTVSDSSAADLADELGSVSADV
CEEEEEECCCCEEECCCCCCEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHCCCEEEE
TGSSGDNTITTGAGNDILSGGDGADTLTGGAGDDIIYGNAGNDKLVGGDGNDRITDGGFG
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEECCCCCCCEECCCEE
FVSGPDGSLQPEIVDIDGGDGDDLITIERFAPLISGTIDGGAGIDTLRASALRSLTIKNV
EEECCCCCCCCEEEEECCCCCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEECCE
EVLELADFQVSGSSSQFESFDKIARSTDPVFNFDPSLIVTDSAHLDLSDELGDLGTLVRG
EEEEEEEEEECCCCHHHHHHHHHHHCCCCCEECCCCEEEECCCCCCCHHHHHHHHHHHHC
FSGIDVKTGDGDDEFAGSNVNDIFDGSGGSDLINGNDGDDKLTGGAGNDTIDGGAGIDTA
CCCCEEECCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AFTGNFADYSFAVDNGSRVVTSVLEGTDRLTDVEFARFADGVYDFATETFTVNSTEPGTP
EEECCCCCEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHCCHHHHCCEEEEECCCCCCCC
LNILDTNGATITKTGAEFEAYDVIRDSEINPLVPVNLVISDSGTVDLSDELGSGSANVIG
EEEEECCCCEEEECCCCCEEEEEEECCCCCCEEEEEEEEECCCCEEECCCCCCCCCEEEE
TSGNDVITTGAGNDNIAGGDGADTLNGGAGYDSLNGGVGNDTLYGGDGNDHISGDVGNDV
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCHH
IRGGAGNDTIDDGELFGLSPEVIDINAGDGNDSISVGTLAPLNSGTVDGGDGIDTLQAAS
EECCCCCCCCCCCEEECCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHH
LRGLTIKNIEVLETAGWSVAGSSAQFESFDKIVWSTDPFGDFRAAVTLTDSAHLDLADEL
CCCEEECCEEEEEECCCEEECCCCCHHHHCCEEECCCCCCCEEEEEEEECCCCCCCHHHH
GDLGAFIDGDAFGIDVRTGGGDDEFTGTDGNDIFDGSGGNDILNGNAGDDKLTGGAGNDT
HCCCEEECCCEEEEEEECCCCCCCCCCCCCCEEECCCCCCCEECCCCCCCCCCCCCCCCC
IDGGAGIDTALFAGNFADYSLALNNGDHILTSVAEGADTLTGVEFARFADGLYDFGTETF
CCCCCCCCHHHEECCCCEEEEEECCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHCCCCEE
TPKGNAAPTNIQLSKTALSEDTPIWTTVGLLSAKDADGDVLTYKLLDGADDHFRINGNRI
CCCCCCCCCEEEEEHHHCCCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCEEEECCCEE
VTSKALDYETAKSHTIKVAVSDGKVTVEKDITINVLDVNETPINQAPIKLSFSRSSISEN
EEEECCCCCCCCCEEEEEEEECCEEEEEECEEEEEEECCCCCCCCCCEEEEECCCCCCCC
VAIGTSVGLLSAVDPEGGTVKWRLTDDADGIFKLVGNKIQTKAAIDFESNHSLTFTAEAY
EEEECCCCEEEEECCCCCEEEEEECCCCCHHHHHHCCCEEEEEEEEECCCCCEEEEEHHH
DAAGNATSHDFTVAVKDIFEPSFSSLLH
CCCCCCCCCEEEEEEHHHCCCCHHHHCC
>Mature Secondary Structure 
ALNILDTNGATITNTGAEFEAYDVIRYSEANPSGPVSLTVSDSSAADLADELGSVSADV
EEEEEECCCCEEECCCCCCEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHCCCEEEE
TGSSGDNTITTGAGNDILSGGDGADTLTGGAGDDIIYGNAGNDKLVGGDGNDRITDGGFG
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEECCCCCCCEECCCEE
FVSGPDGSLQPEIVDIDGGDGDDLITIERFAPLISGTIDGGAGIDTLRASALRSLTIKNV
EEECCCCCCCCEEEEECCCCCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEECCE
EVLELADFQVSGSSSQFESFDKIARSTDPVFNFDPSLIVTDSAHLDLSDELGDLGTLVRG
EEEEEEEEEECCCCHHHHHHHHHHHCCCCCEECCCCEEEECCCCCCCHHHHHHHHHHHHC
FSGIDVKTGDGDDEFAGSNVNDIFDGSGGSDLINGNDGDDKLTGGAGNDTIDGGAGIDTA
CCCCEEECCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AFTGNFADYSFAVDNGSRVVTSVLEGTDRLTDVEFARFADGVYDFATETFTVNSTEPGTP
EEECCCCCEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHCCHHHHCCEEEEECCCCCCCC
LNILDTNGATITKTGAEFEAYDVIRDSEINPLVPVNLVISDSGTVDLSDELGSGSANVIG
EEEEECCCCEEEECCCCCEEEEEEECCCCCCEEEEEEEEECCCCEEECCCCCCCCCEEEE
TSGNDVITTGAGNDNIAGGDGADTLNGGAGYDSLNGGVGNDTLYGGDGNDHISGDVGNDV
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCHH
IRGGAGNDTIDDGELFGLSPEVIDINAGDGNDSISVGTLAPLNSGTVDGGDGIDTLQAAS
EECCCCCCCCCCCEEECCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHH
LRGLTIKNIEVLETAGWSVAGSSAQFESFDKIVWSTDPFGDFRAAVTLTDSAHLDLADEL
CCCEEECCEEEEEECCCEEECCCCCHHHHCCEEECCCCCCCEEEEEEEECCCCCCCHHHH
GDLGAFIDGDAFGIDVRTGGGDDEFTGTDGNDIFDGSGGNDILNGNAGDDKLTGGAGNDT
HCCCEEECCCEEEEEEECCCCCCCCCCCCCCEEECCCCCCCEECCCCCCCCCCCCCCCCC
IDGGAGIDTALFAGNFADYSLALNNGDHILTSVAEGADTLTGVEFARFADGLYDFGTETF
CCCCCCCCHHHEECCCCEEEEEECCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHCCCCEE
TPKGNAAPTNIQLSKTALSEDTPIWTTVGLLSAKDADGDVLTYKLLDGADDHFRINGNRI
CCCCCCCCCEEEEEHHHCCCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCEEEECCCEE
VTSKALDYETAKSHTIKVAVSDGKVTVEKDITINVLDVNETPINQAPIKLSFSRSSISEN
EEEECCCCCCCCCEEEEEEEECCEEEEEECEEEEEEECCCCCCCCCCEEEEECCCCCCCC
VAIGTSVGLLSAVDPEGGTVKWRLTDDADGIFKLVGNKIQTKAAIDFESNHSLTFTAEAY
EEEECCCCEEEEECCCCCEEEEEECCCCCHHHHHHCCCEEEEEEEEECCCCCEEEEEHHH
DAAGNATSHDFTVAVKDIFEPSFSSLLH
CCCCCCCCCEEEEEEHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]