Click here to switch to the map view.

The map label for this gene is dhaK [H]

Identifier: 209549759

GI number: 209549759

Start: 2223629

End: 2225263

Strand: Direct

Name: dhaK [H]

Synonym: Rleg2_2167

Alternate gene names: 209549759

Gene position: 2223629-2225263 (Clockwise)

Preceding gene: 209549753

Following gene: 209549764

Centisome position: 49.0

GC content: 66.97

Gene sequence:

>1635_bases
ATGAAACACTTCTTCAACCGCAGGGAAAACATCGTCACCGAAGCCCTGGACGGCCTGCTTCTGACGAGCCGCAAGGGCCG
TCTTGCCCGCCTCGACAGTTTTCCCGATATCAAGGTGATCCTGCGCGCCGACTGGGACAAGTCGAAGGTGGCGATCATAT
CGGGCGGCGGCGCCGGCCACGAGCCCTCCCATGCCGGCTTTGTCGGAAAGGGCATGCTGACGGCGGCCGTTTCGGGAGAG
ATCTTCGCCTCGCCGAGCGTCGATGCGGTGCTGACGGCAATCCGGGCGGTGACGGGTCCGAAGGGCGCGCTGCTGATCGT
CAAGAATTACACCGGCGACCGCCTGAATTTCGGCCTTGCCGCCGAAAAGGCCCGCGCCGAAGGCTTCGATGTCGAGATGG
TTATCGTCGCCGACGATATCGCCCTGCCCGGCATCAGCCAGCCGCGCGGCGTCGCCGGCACCTTGTTCGTCCACAAGATC
GCAGGCTACCACGCCGAACGAGGTCAGGATCTGAAAACGGTCGCGGCCCAGGCCGGAAGTGCCGCCGGCGATATCGTCTC
ACTCGGCATGTCGCTCTCCACCTGCAGCGTGCCCGGCCAGACGCACGAGGACCGGCTCGGCGCCGACGAAGGCGAACTCG
GCCTCGGCATCCATGGCGAACCGGGCGTCGAGCGCATCGCGCTGCAGCCGGTCGCCGATATCGTTGCCATCATGTCCGCC
CGCCTCTCCGCAACGCCTGGGAATACCGGCGATCACGCGCTGCTCATCAACAATCTCGGCGCCGTGCCGCCACTCGAAAT
GGCCGTCGTCGCCAATGCCGTGCTGGCCACCCCGCTTGGCCGCCGCACCCGCCTGATCATCGGTCCGGCGCCTGTCATGA
CCGCGCTCAACATGAACGGCTTCTCGCTGTCGCTGATCCCGCTGGACGCCGAGCGCGAAGCGGCCCTGACAGCCGCTGTC
GAACCGCATGCCTGGATGCCCGCCGTAGAGCGCCATGGGATCGAGATCATCGCCGCACCGAGGACAGCGAGAGGAGAAGC
CGCAGCCGGCGAAAACCCCGGCAACCGGCGCCTGATCGCGGCACTCTGCGAGCATCTGATTTCGCTGGAAGAGGATCTCA
ACCGCCTGGACGCCCGCGTCGGCGACGGCGATACCGGCTCGACCGTGGCAACAGGCGCCCGCAGCCTGCTCGCCCGCCTC
GACACGCTGCCGCTCGACCGGCCGGCGGCCACCCTTGCCGCGATCGGCGATATTCTCGGCACCAGTATGGGTGGATCGAG
CGGCGTGCTGCTGTCGATCTTCTTCACCGCCGCGGCCAAGGCGATGGCCGACAAATCAAATATATCGGCAGCCCTTCTGG
CCGGGCTCGACCGGATGGCCTTCTACGGCGGAGCGGAGGTCGGCGACCGCACGATGGTCGATGCGCTCTCGCCGGCGCTG
CATGCGCTAGCCTCCGGCGGCGTTGCAGCAGCGGCAAAGGCGGCGGCATCAGGCGCGGAATCGACGAAGGCGATGACCAA
GGCGAAAGCCGGACGTTCCTCCTATGTCGGCGCAAGGGATCTGGCCGATGTGGCCGATCCCGGCGCTGTCGCGGTCGCCG
CAGCCTTCACCGTGGTGGCGGGTCTTCAGACGTAA

Upstream 100 bases:

>100_bases
TCGCCGCGCGATCCCTTTGCTCGATGCGGGTGGACAGCACCTCTTGCGACCGGCAAAAAGGCATGACGACGGCACGAAAC
CAACGGACGGGTCTCAATCG

Downstream 100 bases:

>100_bases
AGCGGAGCCATCCTCCGCCAAGCGCCGGCGCGATGGGCGCGGCCGTCCCATACATGCAGCTGGTGGCGAATATTCTTCTC
GCCCAGCAGCCGGCTGAGAT

Product: glycerone kinase

Products: NA

Alternate protein names: DHA kinase; Glycerone kinase [H]

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MKHFFNRRENIVTEALDGLLLTSRKGRLARLDSFPDIKVILRADWDKSKVAIISGGGAGHEPSHAGFVGKGMLTAAVSGE
IFASPSVDAVLTAIRAVTGPKGALLIVKNYTGDRLNFGLAAEKARAEGFDVEMVIVADDIALPGISQPRGVAGTLFVHKI
AGYHAERGQDLKTVAAQAGSAAGDIVSLGMSLSTCSVPGQTHEDRLGADEGELGLGIHGEPGVERIALQPVADIVAIMSA
RLSATPGNTGDHALLINNLGAVPPLEMAVVANAVLATPLGRRTRLIIGPAPVMTALNMNGFSLSLIPLDAEREAALTAAV
EPHAWMPAVERHGIEIIAAPRTARGEAAAGENPGNRRLIAALCEHLISLEEDLNRLDARVGDGDTGSTVATGARSLLARL
DTLPLDRPAATLAAIGDILGTSMGGSSGVLLSIFFTAAAKAMADKSNISAALLAGLDRMAFYGGAEVGDRTMVDALSPAL
HALASGGVAAAAKAAASGAESTKAMTKAKAGRSSYVGARDLADVADPGAVAVAAAFTVVAGLQT

Sequences:

>Translated_544_residues
MKHFFNRRENIVTEALDGLLLTSRKGRLARLDSFPDIKVILRADWDKSKVAIISGGGAGHEPSHAGFVGKGMLTAAVSGE
IFASPSVDAVLTAIRAVTGPKGALLIVKNYTGDRLNFGLAAEKARAEGFDVEMVIVADDIALPGISQPRGVAGTLFVHKI
AGYHAERGQDLKTVAAQAGSAAGDIVSLGMSLSTCSVPGQTHEDRLGADEGELGLGIHGEPGVERIALQPVADIVAIMSA
RLSATPGNTGDHALLINNLGAVPPLEMAVVANAVLATPLGRRTRLIIGPAPVMTALNMNGFSLSLIPLDAEREAALTAAV
EPHAWMPAVERHGIEIIAAPRTARGEAAAGENPGNRRLIAALCEHLISLEEDLNRLDARVGDGDTGSTVATGARSLLARL
DTLPLDRPAATLAAIGDILGTSMGGSSGVLLSIFFTAAAKAMADKSNISAALLAGLDRMAFYGGAEVGDRTMVDALSPAL
HALASGGVAAAAKAAASGAESTKAMTKAKAGRSSYVGARDLADVADPGAVAVAAAFTVVAGLQT
>Mature_544_residues
MKHFFNRRENIVTEALDGLLLTSRKGRLARLDSFPDIKVILRADWDKSKVAIISGGGAGHEPSHAGFVGKGMLTAAVSGE
IFASPSVDAVLTAIRAVTGPKGALLIVKNYTGDRLNFGLAAEKARAEGFDVEMVIVADDIALPGISQPRGVAGTLFVHKI
AGYHAERGQDLKTVAAQAGSAAGDIVSLGMSLSTCSVPGQTHEDRLGADEGELGLGIHGEPGVERIALQPVADIVAIMSA
RLSATPGNTGDHALLINNLGAVPPLEMAVVANAVLATPLGRRTRLIIGPAPVMTALNMNGFSLSLIPLDAEREAALTAAV
EPHAWMPAVERHGIEIIAAPRTARGEAAAGENPGNRRLIAALCEHLISLEEDLNRLDARVGDGDTGSTVATGARSLLARL
DTLPLDRPAATLAAIGDILGTSMGGSSGVLLSIFFTAAAKAMADKSNISAALLAGLDRMAFYGGAEVGDRTMVDALSPAL
HALASGGVAAAAKAAASGAESTKAMTKAKAGRSSYVGARDLADVADPGAVAVAAAFTVVAGLQT

Specific function: Catalyzes the phosphorylation of dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=566, Percent_Identity=41.1660777385159, Blast_Score=324, Evalue=2e-88,
Organism=Escherichia coli, GI87081857, Length=356, Percent_Identity=34.8314606741573, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1787449, Length=192, Percent_Identity=29.6875, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17565018, Length=570, Percent_Identity=34.7368421052632, Blast_Score=260, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6323570, Length=562, Percent_Identity=35.9430604982206, Blast_Score=269, Evalue=9e-73,
Organism=Saccharomyces cerevisiae, GI6321055, Length=598, Percent_Identity=34.2809364548495, Blast_Score=244, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR004007
- InterPro:   IPR012734 [H]

Pfam domain/function: PF02733 Dak1; PF02734 Dak2 [H]

EC number: =2.7.1.29 [H]

Molecular weight: Translated: 55463; Mature: 55463

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFFNRRENIVTEALDGLLLTSRKGRLARLDSFPDIKVILRADWDKSKVAIISGGGAGH
CCCHHHHHHHHHHHHHCCCEEECCCCCEEECCCCCCEEEEEEECCCCCEEEEEECCCCCC
EPSHAGFVGKGMLTAAVSGEIFASPSVDAVLTAIRAVTGPKGALLIVKNYTGDRLNFGLA
CCCCCCCCCCCCEEEEECCCEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCH
AEKARAEGFDVEMVIVADDIALPGISQPRGVAGTLFVHKIAGYHAERGQDLKTVAAQAGS
HHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHCCCCHHHHHHHHCCC
AAGDIVSLGMSLSTCSVPGQTHEDRLGADEGELGLGIHGEPGVERIALQPVADIVAIMSA
CCCHHHHHCCCEEECCCCCCCCHHHCCCCCCCEEECCCCCCCCHHEEHHHHHHHHHHHHH
RLSATPGNTGDHALLINNLGAVPPLEMAVVANAVLATPLGRRTRLIIGPAPVMTALNMNG
HHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHEECCCC
FSLSLIPLDAEREAALTAAVEPHAWMPAVERHGIEIIAAPRTARGEAAAGENPGNRRLIA
CEEEEEEECCCCCHHEEEECCCCCCCCHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHH
ALCEHLISLEEDLNRLDARVGDGDTGSTVATGARSLLARLDTLPLDRPAATLAAIGDILG
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TSMGGSSGVLLSIFFTAAAKAMADKSNISAALLAGLDRMAFYGGAEVGDRTMVDALSPAL
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
HALASGGVAAAAKAAASGAESTKAMTKAKAGRSSYVGARDLADVADPGAVAVAAAFTVVA
HHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHH
GLQT
CCCC
>Mature Secondary Structure
MKHFFNRRENIVTEALDGLLLTSRKGRLARLDSFPDIKVILRADWDKSKVAIISGGGAGH
CCCHHHHHHHHHHHHHCCCEEECCCCCEEECCCCCCEEEEEEECCCCCEEEEEECCCCCC
EPSHAGFVGKGMLTAAVSGEIFASPSVDAVLTAIRAVTGPKGALLIVKNYTGDRLNFGLA
CCCCCCCCCCCCEEEEECCCEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCH
AEKARAEGFDVEMVIVADDIALPGISQPRGVAGTLFVHKIAGYHAERGQDLKTVAAQAGS
HHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHCCCCHHHHHHHHCCC
AAGDIVSLGMSLSTCSVPGQTHEDRLGADEGELGLGIHGEPGVERIALQPVADIVAIMSA
CCCHHHHHCCCEEECCCCCCCCHHHCCCCCCCEEECCCCCCCCHHEEHHHHHHHHHHHHH
RLSATPGNTGDHALLINNLGAVPPLEMAVVANAVLATPLGRRTRLIIGPAPVMTALNMNG
HHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHEECCCC
FSLSLIPLDAEREAALTAAVEPHAWMPAVERHGIEIIAAPRTARGEAAAGENPGNRRLIA
CEEEEEEECCCCCHHEEEECCCCCCCCHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHH
ALCEHLISLEEDLNRLDARVGDGDTGSTVATGARSLLARLDTLPLDRPAATLAAIGDILG
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TSMGGSSGVLLSIFFTAAAKAMADKSNISAALLAGLDRMAFYGGAEVGDRTMVDALSPAL
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
HALASGGVAAAAKAAASGAESTKAMTKAKAGRSSYVGARDLADVADPGAVAVAAAFTVVA
HHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHH
GLQT
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA