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The map label for this gene is aqpZ1 [H]

Identifier: 209549752

GI number: 209549752

Start: 2215523

End: 2216221

Strand: Direct

Name: aqpZ1 [H]

Synonym: Rleg2_2160

Alternate gene names: 209549752

Gene position: 2215523-2216221 (Clockwise)

Preceding gene: 209549751

Following gene: 209549753

Centisome position: 48.82

GC content: 64.66

Gene sequence:

>699_bases
ATGGCGCCGTTCGATCTGCAGCGCCGACTGGTCGCAGAGGCCATCGGCACCGCCATGCTGGTCGCAACCGTCGTCGGGTC
CGGCATCATGGCGACGTCGCTGACCGAGGATGTCGGGCTTGCCCTGCTCGGCAACACGCTCGCGACCGGCGCCATGCTGG
TAGTGCTGATCACCGTGCTCGGGCCGATCTCCGGTGCCCATTTCAACCCGGCCGTCTCACTGGTCTTCGCAATGTTGCGT
TCGCTGCCGAAACGCGACCTCACGGGATATGTGCTGGCACAGATTGCCGGCGGCGTGGCAGGGACGATCGCCGCCCACCT
GATGTTCGAACTCCCGCTCGTCGAATTCTCCAGCAAGGTTCGCACCGGCGGCGCACAATGGTTCTCCGAAGGTGTGGCGA
CCTTCGGCCTGGTCGCGGTCATTCTCGCCGGCATCCGGTTCGAGCAGAAAGCGGTGCCATGGCTGGTCGGCCTCTACATC
ACCGCCGCCTATTGGTTCACCGCCTCCACCTCGTTCGCCAACCCGGCCGTTGCGCTCGCCCGCTCCCTGACCAACACTTT
TTCCGGCATCCGCCCGGTCGATCTTCCGGGCTTCTGGCTTGCCGAAATCGCCGGCGCGCTCCTTGCGCTCATTCTTTTCA
CCTGGCTGCTGCAGCCGGCCGAGACATCGTCAACCCTATCCAGTGAGGCGAAGCTATGA

Upstream 100 bases:

>100_bases
GCGCGCCGGCTGCCGCCGTCGCGGCATGCTGTTCCACCGCGATGAAGGGAGACCTTGCAATGACCCCGAGCACGACCGCA
AAAGCGGCGACGGCCGACTG

Downstream 100 bases:

>100_bases
ACGTCACCATCTACCACAACCCGGCATGCGGCACCTCGCGCAATACGCTGGCGATGATCCGCAATGCAGGCATCGAACCC
ACCGTCATCGAATACGTCAA

Product: major intrinsic protein

Products: H2O [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MAPFDLQRRLVAEAIGTAMLVATVVGSGIMATSLTEDVGLALLGNTLATGAMLVVLITVLGPISGAHFNPAVSLVFAMLR
SLPKRDLTGYVLAQIAGGVAGTIAAHLMFELPLVEFSSKVRTGGAQWFSEGVATFGLVAVILAGIRFEQKAVPWLVGLYI
TAAYWFTASTSFANPAVALARSLTNTFSGIRPVDLPGFWLAEIAGALLALILFTWLLQPAETSSTLSSEAKL

Sequences:

>Translated_232_residues
MAPFDLQRRLVAEAIGTAMLVATVVGSGIMATSLTEDVGLALLGNTLATGAMLVVLITVLGPISGAHFNPAVSLVFAMLR
SLPKRDLTGYVLAQIAGGVAGTIAAHLMFELPLVEFSSKVRTGGAQWFSEGVATFGLVAVILAGIRFEQKAVPWLVGLYI
TAAYWFTASTSFANPAVALARSLTNTFSGIRPVDLPGFWLAEIAGALLALILFTWLLQPAETSSTLSSEAKL
>Mature_231_residues
APFDLQRRLVAEAIGTAMLVATVVGSGIMATSLTEDVGLALLGNTLATGAMLVVLITVLGPISGAHFNPAVSLVFAMLRS
LPKRDLTGYVLAQIAGGVAGTIAAHLMFELPLVEFSSKVRTGGAQWFSEGVATFGLVAVILAGIRFEQKAVPWLVGLYIT
AAYWFTASTSFANPAVALARSLTNTFSGIRPVDLPGFWLAEIAGALLALILFTWLLQPAETSSTLSSEAKL

Specific function: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response

COG id: COG0580

COG function: function code G; Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family [H]

Homologues:

Organism=Escherichia coli, GI1787101, Length=102, Percent_Identity=37.2549019607843, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012269
- InterPro:   IPR000425
- InterPro:   IPR022357 [H]

Pfam domain/function: PF00230 MIP [H]

EC number: NA

Molecular weight: Translated: 24267; Mature: 24136

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPFDLQRRLVAEAIGTAMLVATVVGSGIMATSLTEDVGLALLGNTLATGAMLVVLITVL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GPISGAHFNPAVSLVFAMLRSLPKRDLTGYVLAQIAGGVAGTIAAHLMFELPLVEFSSKV
HCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RTGGAQWFSEGVATFGLVAVILAGIRFEQKAVPWLVGLYITAAYWFTASTSFANPAVALA
HCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RSLTNTFSGIRPVDLPGFWLAEIAGALLALILFTWLLQPAETSSTLSSEAKL
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
APFDLQRRLVAEAIGTAMLVATVVGSGIMATSLTEDVGLALLGNTLATGAMLVVLITVL
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GPISGAHFNPAVSLVFAMLRSLPKRDLTGYVLAQIAGGVAGTIAAHLMFELPLVEFSSKV
HCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RTGGAQWFSEGVATFGLVAVILAGIRFEQKAVPWLVGLYITAAYWFTASTSFANPAVALA
HCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RSLTNTFSGIRPVDLPGFWLAEIAGALLALILFTWLLQPAETSSTLSSEAKL
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O [Periplasm] [C]

Specific reaction: H2O [Periplasm] = H2O [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]