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The map label for this gene is rihC [H]

Identifier: 209549718

GI number: 209549718

Start: 2183362

End: 2184312

Strand: Reverse

Name: rihC [H]

Synonym: Rleg2_2125

Alternate gene names: 209549718

Gene position: 2184312-2183362 (Counterclockwise)

Preceding gene: 209549719

Following gene: 209549717

Centisome position: 48.13

GC content: 62.78

Gene sequence:

>951_bases
ATGCACAAGGTCATTTATGACACGGACCCGGGCGTCGACGATGCCATGGCGCTTCTTTTCCTGCACCGCCATCCCGAAAT
CGATCTGATTGGTATCACCACCGTTTTCGGCAATGCCTCGGTTGAGACGACAACCCGCAATGCGCTTTTCCTCAAGCGGG
AATGGGGTATCGCAGCGCCGGTTGCCAAGGGCGCCAGCGTCACCATAGATCCCTCCCGCGCCGAGCGGGAATGGCCGGCG
ATGGTGCATGGCGACAACGGTCTCGGCGATATCGAAGTGCCGGAGATGAGCGACCTGCCGCTCGATCCGCGCCCGGCGCA
TCGCTTCATCATCGACATGGTCCGCGCCAACCCCGGCGAGGTGCGGCTTGTCGCTGTCGGGCGGATGACCAATCTGGCGC
GGGCGCTGAAGGAAGACCCGGAGATAGCGGGCCTGGTCAAGGACGTCGTCATCATGGGCGGCAATTTCTATGTGCCGGGC
AATGTCTCGCCGGTCGCCGAAGCCAATATCCACGGCGATCCCGAAGCGGCCGACATCGTCATGACCGCGCCCTGGAAGGT
CGCCGTCATCGGCCTCGACGTCACCTCGATCACCACGATGAGCCGCAGCTATCTCGGCGAGATGGCGGCGAAGGGCGACG
GGGCGGTAAAGCTGCTCGACGCACTGTCGCAGTCCTACATCGATTTCTACAAGCATGCGGTCGAAGACGGCATGATGGTG
CATGACAGCTGCGCCGCGGTCTATGTCGTGGCGCCGGAACTGTTCTCGTCGATATCGGGTGCGGTGCGCGTCGTCTGCGG
CGGCATTGCCGACGGCCAGACAATCGTCAAGCCGGACGGTCGCCGTTTCCCGCCGGGCGACTGGGATGGTCTACCGAGCC
AGATCGTCTGCACCGGTATCGAATCGGAGAAAGTCATCGACCTTATCCGCAAGGCGCTGCTTCGCGTTTGA

Upstream 100 bases:

>100_bases
ATTGCCCGCATCGGGTTGCAGAAAGACTGACGGGCGTTATGGTGGCGGCAATTCGCGGCGCCGTCCGGCAGCTCGCGGTT
TACATATAAAAGGATACTCC

Downstream 100 bases:

>100_bases
CCGACTGGGAGGCCGGCTGCATTGCGGCCGGCCTTTGCGATCATATGATAATATATTCATATAGTTATTCGGATTTTCGG
AGAATTCGAATCCGCTTTCT

Product: inosine/uridine-preferring nucleoside hydrolase

Products: NA

Alternate protein names: Purine/pyrimidine ribonucleoside hydrolase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MHKVIYDTDPGVDDAMALLFLHRHPEIDLIGITTVFGNASVETTTRNALFLKREWGIAAPVAKGASVTIDPSRAEREWPA
MVHGDNGLGDIEVPEMSDLPLDPRPAHRFIIDMVRANPGEVRLVAVGRMTNLARALKEDPEIAGLVKDVVIMGGNFYVPG
NVSPVAEANIHGDPEAADIVMTAPWKVAVIGLDVTSITTMSRSYLGEMAAKGDGAVKLLDALSQSYIDFYKHAVEDGMMV
HDSCAAVYVVAPELFSSISGAVRVVCGGIADGQTIVKPDGRRFPPGDWDGLPSQIVCTGIESEKVIDLIRKALLRV

Sequences:

>Translated_316_residues
MHKVIYDTDPGVDDAMALLFLHRHPEIDLIGITTVFGNASVETTTRNALFLKREWGIAAPVAKGASVTIDPSRAEREWPA
MVHGDNGLGDIEVPEMSDLPLDPRPAHRFIIDMVRANPGEVRLVAVGRMTNLARALKEDPEIAGLVKDVVIMGGNFYVPG
NVSPVAEANIHGDPEAADIVMTAPWKVAVIGLDVTSITTMSRSYLGEMAAKGDGAVKLLDALSQSYIDFYKHAVEDGMMV
HDSCAAVYVVAPELFSSISGAVRVVCGGIADGQTIVKPDGRRFPPGDWDGLPSQIVCTGIESEKVIDLIRKALLRV
>Mature_316_residues
MHKVIYDTDPGVDDAMALLFLHRHPEIDLIGITTVFGNASVETTTRNALFLKREWGIAAPVAKGASVTIDPSRAEREWPA
MVHGDNGLGDIEVPEMSDLPLDPRPAHRFIIDMVRANPGEVRLVAVGRMTNLARALKEDPEIAGLVKDVVIMGGNFYVPG
NVSPVAEANIHGDPEAADIVMTAPWKVAVIGLDVTSITTMSRSYLGEMAAKGDGAVKLLDALSQSYIDFYKHAVEDGMMV
HDSCAAVYVVAPELFSSISGAVRVVCGGIADGQTIVKPDGRRFPPGDWDGLPSQIVCTGIESEKVIDLIRKALLRV

Specific function: Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity [H]

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family. RihC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786213, Length=278, Percent_Identity=38.8489208633094, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1788486, Length=279, Percent_Identity=32.6164874551971, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786871, Length=280, Percent_Identity=32.8571428571429, Blast_Score=116, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32565474, Length=197, Percent_Identity=34.010152284264, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565698, Length=191, Percent_Identity=36.1256544502618, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6320608, Length=251, Percent_Identity=33.0677290836653, Blast_Score=99, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24641839, Length=202, Percent_Identity=34.1584158415842, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24583915, Length=196, Percent_Identity=32.6530612244898, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641837, Length=240, Percent_Identity=30.8333333333333, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910
- InterPro:   IPR022976 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: 3.2.2.-

Molecular weight: Translated: 33947; Mature: 33947

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKVIYDTDPGVDDAMALLFLHRHPEIDLIGITTVFGNASVETTTRNALFLKREWGIAAP
CCCEEECCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEECCCEEEEEECCCCCCC
VAKGASVTIDPSRAEREWPAMVHGDNGLGDIEVPEMSDLPLDPRPAHRFIIDMVRANPGE
CCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
VRLVAVGRMTNLARALKEDPEIAGLVKDVVIMGGNFYVPGNVSPVAEANIHGDPEAADIV
EEEEEECCHHHHHHHHHCCCHHHHHHHHHEEECCCEEECCCCCCCEECCCCCCCCCCCEE
MTAPWKVAVIGLDVTSITTMSRSYLGEMAAKGDGAVKLLDALSQSYIDFYKHAVEDGMMV
EECCCEEEEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
HDSCAAVYVVAPELFSSISGAVRVVCGGIADGQTIVKPDGRRFPPGDWDGLPSQIVCTGI
ECCCCEEEEECHHHHHHHHHEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCEEEECC
ESEKVIDLIRKALLRV
CHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHKVIYDTDPGVDDAMALLFLHRHPEIDLIGITTVFGNASVETTTRNALFLKREWGIAAP
CCCEEECCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEECCCEEEEEECCCCCCC
VAKGASVTIDPSRAEREWPAMVHGDNGLGDIEVPEMSDLPLDPRPAHRFIIDMVRANPGE
CCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
VRLVAVGRMTNLARALKEDPEIAGLVKDVVIMGGNFYVPGNVSPVAEANIHGDPEAADIV
EEEEEECCHHHHHHHHHCCCHHHHHHHHHEEECCCEEECCCCCCCEECCCCCCCCCCCEE
MTAPWKVAVIGLDVTSITTMSRSYLGEMAAKGDGAVKLLDALSQSYIDFYKHAVEDGMMV
EECCCEEEEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
HDSCAAVYVVAPELFSSISGAVRVVCGGIADGQTIVKPDGRRFPPGDWDGLPSQIVCTGI
ECCCCEEEEECHHHHHHHHHEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCEEEECC
ESEKVIDLIRKALLRV
CHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA