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The map label for this gene is fabZ [H]

Identifier: 209549709

GI number: 209549709

Start: 2176165

End: 2176647

Strand: Reverse

Name: fabZ [H]

Synonym: Rleg2_2116

Alternate gene names: 209549709

Gene position: 2176647-2176165 (Counterclockwise)

Preceding gene: 209549710

Following gene: 209549708

Centisome position: 47.97

GC content: 61.28

Gene sequence:

>483_bases
ATGCTGCTGGAATATTTCCAGATGATTGACCGCGTCGAAGCGGTGGACCTGAAGAAGGGCACGCTGAACGCGCGATCCGT
CGTGCCGGCCAAGAGCCCCGTCTTCGAGGGTCATTTTCCCGGCATGCCGCTCGTTCCCGGTGTGCTGTTGATCGAGACGA
TGGCGCAGGCCTCCGGCATGCTGGTGCTTGCCGCCACCAACTTCGCCGCCATGCCCTTCCTGATGTCGGTCGACGGCGCC
AAGATGCGCACATTCGTCGAGCCAGAGGCCGTGCTCGACATCGAGGCGGTGCTTGAGCACGACGGCTCAGGTTTCGCGGT
GACCAAAGCTAAAATCACCAGCGCCGGCAAGAAGGTCTGTGATGCGCAGCTGAAGCTTCGCACCATGCCGTTTTCCGAAG
TGCCGCTCGGCGATATCGTGAAAAAACGTGCCGGCGAGATTGGGCTTCTCGAAGCGATCGCGGCGCAGGGAGTGGTAGGA
TGA

Upstream 100 bases:

>100_bases
TTTTGAGCGCCCTGCCGCCTGACTATGGCGGCTGGGCGGTTTCGTTCCTAACTAGGCGTCACCGGCGGGCGGATCTGGCC
TGTCGGGCCGGAGGATCCGA

Downstream 100 bases:

>100_bases
GCAAGGCTGCAAACGACGTCGTCATCTCGGGCATCGGTATCGTCACCTGTCAGGGCGTCGGCAAGGATGCGCATATCGCG
CTGCTTTCGGCGGCAAGCGC

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MLLEYFQMIDRVEAVDLKKGTLNARSVVPAKSPVFEGHFPGMPLVPGVLLIETMAQASGMLVLAATNFAAMPFLMSVDGA
KMRTFVEPEAVLDIEAVLEHDGSGFAVTKAKITSAGKKVCDAQLKLRTMPFSEVPLGDIVKKRAGEIGLLEAIAAQGVVG

Sequences:

>Translated_160_residues
MLLEYFQMIDRVEAVDLKKGTLNARSVVPAKSPVFEGHFPGMPLVPGVLLIETMAQASGMLVLAATNFAAMPFLMSVDGA
KMRTFVEPEAVLDIEAVLEHDGSGFAVTKAKITSAGKKVCDAQLKLRTMPFSEVPLGDIVKKRAGEIGLLEAIAAQGVVG
>Mature_160_residues
MLLEYFQMIDRVEAVDLKKGTLNARSVVPAKSPVFEGHFPGMPLVPGVLLIETMAQASGMLVLAATNFAAMPFLMSVDGA
KMRTFVEPEAVLDIEAVLEHDGSGFAVTKAKITSAGKKVCDAQLKLRTMPFSEVPLGDIVKKRAGEIGLLEAIAAQGVVG

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=123, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16986; Mature: 16986

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEYFQMIDRVEAVDLKKGTLNARSVVPAKSPVFEGHFPGMPLVPGVLLIETMAQASGM
CHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCE
LVLAATNFAAMPFLMSVDGAKMRTFVEPEAVLDIEAVLEHDGSGFAVTKAKITSAGKKVC
EEEEECCCHHHHHEEECCCCHHEEEECCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
DAQLKLRTMPFSEVPLGDIVKKRAGEIGLLEAIAAQGVVG
HHHHEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MLLEYFQMIDRVEAVDLKKGTLNARSVVPAKSPVFEGHFPGMPLVPGVLLIETMAQASGM
CHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCE
LVLAATNFAAMPFLMSVDGAKMRTFVEPEAVLDIEAVLEHDGSGFAVTKAKITSAGKKVC
EEEEECCCHHHHHEEECCCCHHEEEECCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
DAQLKLRTMPFSEVPLGDIVKKRAGEIGLLEAIAAQGVVG
HHHHEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA