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The map label for this gene is ompR [H]

Identifier: 209549644

GI number: 209549644

Start: 2114060

End: 2114800

Strand: Reverse

Name: ompR [H]

Synonym: Rleg2_2051

Alternate gene names: 209549644

Gene position: 2114800-2114060 (Counterclockwise)

Preceding gene: 209549645

Following gene: 209549643

Centisome position: 46.6

GC content: 63.83

Gene sequence:

>741_bases
ATGGATCATGTCGATCACATCCTGGTCGTCGACGACGATCGCGAAATCCGCGAGCTGGTTTCGGGCTATCTGCAGAAGAA
TGGTTTGAGGACCAGCACTGCCGCGGACGGGCGCCAGATGCGCAGCTTTCTCGAAGCCAACGCCGTCGATCTGATCGTGC
TCGACGTGATGATGCCCGGCGACGACGGGCTGGTGCTGTGCCGCGAACTGCGCGCCGGCCGGCACAAGGCGATCCCGATC
CTGATGCTGACGGCCCGCACCGATGAGATGGACCGGATCCTCGGGCTGGAGATGGGCGCCGACGACTATCTCGCCAAGCC
CTTTGCCGCACGCGAGCTGCTTGCCCGGATCAAGGCAGTGCTGAGGCGCACGCGCATGCTGCCGCCGAACCTGCAGATCA
GCGAGGCCGGGCAGTTGCTGAGCTTCGGCGACTGGCGGCTCGATACGGTCGCCCGGCATCTTCTCGACAAGGAGGGGACC
GCGATCGCACTCAGCGGCGCCGAGTACCGGCTGCTTCGCGTCTTCATCGATCACCCGCAGCGGGTGCTCACTCGCGACCA
GCTTCTGAGCCTGACGCAGGGCCGTGATGCCGATCTTTTCGATCGTTCGATCGATCTCCTGGTCAGCCGCCTGCGGCAGC
GGCTGGGAGACGATGCGCGCGAACCGACCTACATCAAGACGGTGCGCAGTGAAGGCTATGTATTTTCCGTTCCGGTCGAA
ATCATGGAGCTGCGCCAATGA

Upstream 100 bases:

>100_bases
CTCGTTGCCTGGGCCGGCGGAATATGCGTAGGTCGCATCAGCCGCCTCGATATCGAGGAGGAGGGCGCGGCCGCTTCTAT
CGGTAAGGGAACAGGAACAT

Downstream 100 bases:

>100_bases
GGGCGATCCCCTGGTTCTCGGGTTTGATGTGGCCGAGGACGTTGCGGTCGCGGATCTTCCTCATCCTGCTCATCGGTCTC
GCCCTTGCCTACGGGCTGTC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MDHVDHILVVDDDREIRELVSGYLQKNGLRTSTAADGRQMRSFLEANAVDLIVLDVMMPGDDGLVLCRELRAGRHKAIPI
LMLTARTDEMDRILGLEMGADDYLAKPFAARELLARIKAVLRRTRMLPPNLQISEAGQLLSFGDWRLDTVARHLLDKEGT
AIALSGAEYRLLRVFIDHPQRVLTRDQLLSLTQGRDADLFDRSIDLLVSRLRQRLGDDAREPTYIKTVRSEGYVFSVPVE
IMELRQ

Sequences:

>Translated_246_residues
MDHVDHILVVDDDREIRELVSGYLQKNGLRTSTAADGRQMRSFLEANAVDLIVLDVMMPGDDGLVLCRELRAGRHKAIPI
LMLTARTDEMDRILGLEMGADDYLAKPFAARELLARIKAVLRRTRMLPPNLQISEAGQLLSFGDWRLDTVARHLLDKEGT
AIALSGAEYRLLRVFIDHPQRVLTRDQLLSLTQGRDADLFDRSIDLLVSRLRQRLGDDAREPTYIKTVRSEGYVFSVPVE
IMELRQ
>Mature_246_residues
MDHVDHILVVDDDREIRELVSGYLQKNGLRTSTAADGRQMRSFLEANAVDLIVLDVMMPGDDGLVLCRELRAGRHKAIPI
LMLTARTDEMDRILGLEMGADDYLAKPFAARELLARIKAVLRRTRMLPPNLQISEAGQLLSFGDWRLDTVARHLLDKEGT
AIALSGAEYRLLRVFIDHPQRVLTRDQLLSLTQGRDADLFDRSIDLLVSRLRQRLGDDAREPTYIKTVRSEGYVFSVPVE
IMELRQ

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=42.5531914893617, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=33.6170212765957, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=37.9310344827586, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788394, Length=234, Percent_Identity=36.7521367521368, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1787229, Length=238, Percent_Identity=35.7142857142857, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=36.2869198312236, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=37.0689655172414, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=36.6379310344828, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=33.6244541484716, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=34.051724137931, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=33.1877729257642, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=32.618025751073, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=32.1739130434783, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=31.8777292576419, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790299, Length=130, Percent_Identity=31.5384615384615, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=32.520325203252, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1788550, Length=171, Percent_Identity=28.0701754385965, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790437, Length=156, Percent_Identity=31.4102564102564, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=104, Percent_Identity=34.6153846153846, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27933; Mature: 27933

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHVDHILVVDDDREIRELVSGYLQKNGLRTSTAADGRQMRSFLEANAVDLIVLDVMMPG
CCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEECC
DDGLVLCRELRAGRHKAIPILMLTARTDEMDRILGLEMGADDYLAKPFAARELLARIKAV
CCCHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHH
LRRTRMLPPNLQISEAGQLLSFGDWRLDTVARHLLDKEGTAIALSGAEYRLLRVFIDHPQ
HHHHHCCCCCCCHHCCCCCHHCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCH
RVLTRDQLLSLTQGRDADLFDRSIDLLVSRLRQRLGDDAREPTYIKTVRSEGYVFSVPVE
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCHH
IMELRQ
HHHHCC
>Mature Secondary Structure
MDHVDHILVVDDDREIRELVSGYLQKNGLRTSTAADGRQMRSFLEANAVDLIVLDVMMPG
CCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEECC
DDGLVLCRELRAGRHKAIPILMLTARTDEMDRILGLEMGADDYLAKPFAARELLARIKAV
CCCHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHH
LRRTRMLPPNLQISEAGQLLSFGDWRLDTVARHLLDKEGTAIALSGAEYRLLRVFIDHPQ
HHHHHCCCCCCCHHCCCCCHHCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCH
RVLTRDQLLSLTQGRDADLFDRSIDLLVSRLRQRLGDDAREPTYIKTVRSEGYVFSVPVE
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCHH
IMELRQ
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]