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The map label for this gene is mcpA [H]

Identifier: 209549591

GI number: 209549591

Start: 2055837

End: 2057711

Strand: Direct

Name: mcpA [H]

Synonym: Rleg2_1998

Alternate gene names: 209549591

Gene position: 2055837-2057711 (Clockwise)

Preceding gene: 209549590

Following gene: 209549592

Centisome position: 45.3

GC content: 60.85

Gene sequence:

>1875_bases
ATGTTCCAATTTTTGAAAACGATGCCTCTGACAGCCAAGCTGGCGGCGATTATCGTGACCGTCAACCTTTGCGGCATCTC
CGCCTTTGCCACTTACACCTGGATGTACGAAACCAAGGCGTTGATCGATGGCGCCAAGGCCAACTGGTCCAAAGATGCGG
AGCAGTTTGCGTCTCTGGCCGCCGGCGGCGTGAAATGGGGCAAGGCGAATGCTGTGCGCGAGGCCTATTCGCTCTATCGC
GACGACCCCTCGCTTGATCTTGTGCAGTTTGCCGCCTTCAACGCCGAACCTGCCGCCGTTGATACATGGACACGCGACGG
CATCAGCGGTTTGCCGGCACCTGCCGATCTGGCAAAGAGCCTCAGCGCCAAGCCTGAGAAAACGACGATCGATGACAGCG
GAATATCTGCCGGCGTTGTGACGATCATTGCGCCGCTTCCGCTGGATAAATCGGGCAAGGCGACCGGTTACGTCGTAACC
AATTGGTCGGTCGAAAAAATCGCGGCCGAAGTCAAGCAGAAGGTCCTGATTTCGCTGCTGACGCAGTTCGTCATCACCGC
CCTCGCCGTTGTCGCCTTCCTTCTAGCCATGCGTAGCCTCGTCGGCCGCCCCCTCCGGGTTCTCAGCGAACGGATCAGCG
CGTTGCAGAAGGGTGATCTGGCCTCTCCCGTCACCTACAGGGAAAATGGCGACGAGATCGGTTTTCTCGCACGTGCCTTG
GAAGTTTTCCGCAACGAGGCGATTGCCAAGGTTGAAAGAGAGCAGGCCGCGGCCGAGCAGAGCGCCTCATTCGATGCCGA
ACGGGCGCGTAACGCCTCCTTGACGGAGGAAGCCAGCAACGCTCAGCGGCTGGTCATGACAGCGCTCGCAAATGAATTGG
AAAAGCTCGCCGCCGGCGACTTCTCGATCCACCTCGCCGATCTCGGCCCCGAATTCGATAAACTGCGGCAGGATTTCAAC
CGCATGGTCGAAGCGGTTGCCGCCGCATTGACCGAGATCAAGATCGCTTCCGTCGCGGTTGAAGGCGGGTCGAGCGAGCT
TGCCTCCTCCGCCGATCAGCTCGCCAAGCGGACAGAGCAGCAGGCGGCAGCCTTGGAACAGACCGCAGCAGCACTGGACG
AGGTGACCACCACAGTCAGAACGTCGTCACAGCGGGCCGAGAGTGCCGGAAAGCTGGTCGAGGAAACGAAGCGCAGCGCC
CATGTCTCGGCGACGGTGGTACGCGACGCGATCGGGGCGATGGACCGGATCCAGACCTCGTCGAGCCAGATCGGCCGCAT
CATCGGTGTCATCGATGAAATCGCGTTCCAGACGAACCTGCTTGCGCTGAACGCCGGTGTCGAGGCGGCGCGTGCCGGCG
AAGCCGGCAAGGGTTTTGCGGTCGTCGCGCAGGAAGTGCGCGAACTCGCGCAACGGTCCGCCAATGCGGCAAAGGAAATC
AAGAACCTGATCAGCGTCTCCGGTCAGGAAGTGGCAGCCGGCGTCGGGCTGGTGAACGAAACCGGCGATGCCCTCTTGAA
GATCGAGGAGCAGATCAACCGCATCAGCGACAGCATCGCCTCGATTGTCCATTCTTATCGCGAACAGGCGACCGGCCTCC
AGGAAATCAATGGCGCCATCAATCAGATGGATCAGGCCACACAGCAGAACGCGGCCATGGTCGAAGAGACCAACGCGGCT
TGCCAAGAGCTGCGCACACAGGGACGCCTTCTGCAGGATTCGGCCGGCAGGTTCACTGTCGCAACCTACGCCGCCAGCCA
GCCCAAAGCGGCTCAACCCGTTCGTCAATCTCGCCCGGAACAGAGAGTATTTTCGCAGCGCCATGCGGGCAACACCGCCA
TCGCCGCTTCTCCCGATGCCTGGGAAGAGTTCTGA

Upstream 100 bases:

>100_bases
TGGGCATGAGCGCTCGTGATGTGACCGTCAGCGTGGATGCCCGTGTTGATACGCCGGTCGGGAACAGATCCGACTGAGCC
GCAATTCCAGGCCCCGCGGA

Downstream 100 bases:

>100_bases
CGCCAACTTCACTCGATAAGCTTTCAATCCTCAATACCCCAAAATCGGGAAGGGAACAGTTATGAAGAAAGTCGTGACCG
CATTTCTTTTGGCCTGCACC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MFQFLKTMPLTAKLAAIIVTVNLCGISAFATYTWMYETKALIDGAKANWSKDAEQFASLAAGGVKWGKANAVREAYSLYR
DDPSLDLVQFAAFNAEPAAVDTWTRDGISGLPAPADLAKSLSAKPEKTTIDDSGISAGVVTIIAPLPLDKSGKATGYVVT
NWSVEKIAAEVKQKVLISLLTQFVITALAVVAFLLAMRSLVGRPLRVLSERISALQKGDLASPVTYRENGDEIGFLARAL
EVFRNEAIAKVEREQAAAEQSASFDAERARNASLTEEASNAQRLVMTALANELEKLAAGDFSIHLADLGPEFDKLRQDFN
RMVEAVAAALTEIKIASVAVEGGSSELASSADQLAKRTEQQAAALEQTAAALDEVTTTVRTSSQRAESAGKLVEETKRSA
HVSATVVRDAIGAMDRIQTSSSQIGRIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAKEI
KNLISVSGQEVAAGVGLVNETGDALLKIEEQINRISDSIASIVHSYREQATGLQEINGAINQMDQATQQNAAMVEETNAA
CQELRTQGRLLQDSAGRFTVATYAASQPKAAQPVRQSRPEQRVFSQRHAGNTAIAASPDAWEEF

Sequences:

>Translated_624_residues
MFQFLKTMPLTAKLAAIIVTVNLCGISAFATYTWMYETKALIDGAKANWSKDAEQFASLAAGGVKWGKANAVREAYSLYR
DDPSLDLVQFAAFNAEPAAVDTWTRDGISGLPAPADLAKSLSAKPEKTTIDDSGISAGVVTIIAPLPLDKSGKATGYVVT
NWSVEKIAAEVKQKVLISLLTQFVITALAVVAFLLAMRSLVGRPLRVLSERISALQKGDLASPVTYRENGDEIGFLARAL
EVFRNEAIAKVEREQAAAEQSASFDAERARNASLTEEASNAQRLVMTALANELEKLAAGDFSIHLADLGPEFDKLRQDFN
RMVEAVAAALTEIKIASVAVEGGSSELASSADQLAKRTEQQAAALEQTAAALDEVTTTVRTSSQRAESAGKLVEETKRSA
HVSATVVRDAIGAMDRIQTSSSQIGRIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAKEI
KNLISVSGQEVAAGVGLVNETGDALLKIEEQINRISDSIASIVHSYREQATGLQEINGAINQMDQATQQNAAMVEETNAA
CQELRTQGRLLQDSAGRFTVATYAASQPKAAQPVRQSRPEQRVFSQRHAGNTAIAASPDAWEEF
>Mature_624_residues
MFQFLKTMPLTAKLAAIIVTVNLCGISAFATYTWMYETKALIDGAKANWSKDAEQFASLAAGGVKWGKANAVREAYSLYR
DDPSLDLVQFAAFNAEPAAVDTWTRDGISGLPAPADLAKSLSAKPEKTTIDDSGISAGVVTIIAPLPLDKSGKATGYVVT
NWSVEKIAAEVKQKVLISLLTQFVITALAVVAFLLAMRSLVGRPLRVLSERISALQKGDLASPVTYRENGDEIGFLARAL
EVFRNEAIAKVEREQAAAEQSASFDAERARNASLTEEASNAQRLVMTALANELEKLAAGDFSIHLADLGPEFDKLRQDFN
RMVEAVAAALTEIKIASVAVEGGSSELASSADQLAKRTEQQAAALEQTAAALDEVTTTVRTSSQRAESAGKLVEETKRSA
HVSATVVRDAIGAMDRIQTSSSQIGRIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAKEI
KNLISVSGQEVAAGVGLVNETGDALLKIEEQINRISDSIASIVHSYREQATGLQEINGAINQMDQATQQNAAMVEETNAA
CQELRTQGRLLQDSAGRFTVATYAASQPKAAQPVRQSRPEQRVFSQRHAGNTAIAASPDAWEEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=305, Percent_Identity=39.0163934426229, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1787690, Length=326, Percent_Identity=38.3435582822086, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI1788195, Length=322, Percent_Identity=39.4409937888199, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI2367378, Length=266, Percent_Identity=40.9774436090226, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1789453, Length=236, Percent_Identity=40.6779661016949, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 66511; Mature: 66511

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQFLKTMPLTAKLAAIIVTVNLCGISAFATYTWMYETKALIDGAKANWSKDAEQFASLA
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
AGGVKWGKANAVREAYSLYRDDPSLDLVQFAAFNAEPAAVDTWTRDGISGLPAPADLAKS
HCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LSAKPEKTTIDDSGISAGVVTIIAPLPLDKSGKATGYVVTNWSVEKIAAEVKQKVLISLL
HCCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
TQFVITALAVVAFLLAMRSLVGRPLRVLSERISALQKGDLASPVTYRENGDEIGFLARAL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
EVFRNEAIAKVEREQAAAEQSASFDAERARNASLTEEASNAQRLVMTALANELEKLAAGD
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
FSIHLADLGPEFDKLRQDFNRMVEAVAAALTEIKIASVAVEGGSSELASSADQLAKRTEQ
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHH
QAAALEQTAAALDEVTTTVRTSSQRAESAGKLVEETKRSAHVSATVVRDAIGAMDRIQTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SSQIGRIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAKEI
HHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KNLISVSGQEVAAGVGLVNETGDALLKIEEQINRISDSIASIVHSYREQATGLQEINGAI
HHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
NQMDQATQQNAAMVEETNAACQELRTQGRLLQDSAGRFTVATYAASQPKAAQPVRQSRPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCCCCCCCHHHCCCH
QRVFSQRHAGNTAIAASPDAWEEF
HHHHHHHCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MFQFLKTMPLTAKLAAIIVTVNLCGISAFATYTWMYETKALIDGAKANWSKDAEQFASLA
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
AGGVKWGKANAVREAYSLYRDDPSLDLVQFAAFNAEPAAVDTWTRDGISGLPAPADLAKS
HCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LSAKPEKTTIDDSGISAGVVTIIAPLPLDKSGKATGYVVTNWSVEKIAAEVKQKVLISLL
HCCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
TQFVITALAVVAFLLAMRSLVGRPLRVLSERISALQKGDLASPVTYRENGDEIGFLARAL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
EVFRNEAIAKVEREQAAAEQSASFDAERARNASLTEEASNAQRLVMTALANELEKLAAGD
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
FSIHLADLGPEFDKLRQDFNRMVEAVAAALTEIKIASVAVEGGSSELASSADQLAKRTEQ
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHH
QAAALEQTAAALDEVTTTVRTSSQRAESAGKLVEETKRSAHVSATVVRDAIGAMDRIQTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SSQIGRIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAKEI
HHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KNLISVSGQEVAAGVGLVNETGDALLKIEEQINRISDSIASIVHSYREQATGLQEINGAI
HHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
NQMDQATQQNAAMVEETNAACQELRTQGRLLQDSAGRFTVATYAASQPKAAQPVRQSRPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCCCCCCCHHHCCCH
QRVFSQRHAGNTAIAASPDAWEEF
HHHHHHHCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]