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The map label for this gene is hcaT [H]

Identifier: 209549580

GI number: 209549580

Start: 2038803

End: 2040020

Strand: Reverse

Name: hcaT [H]

Synonym: Rleg2_1986

Alternate gene names: 209549580

Gene position: 2040020-2038803 (Counterclockwise)

Preceding gene: 209549581

Following gene: 209549578

Centisome position: 44.95

GC content: 63.38

Gene sequence:

>1218_bases
ATGATTCCCGCTCAACATTCCCCGGGTGAGGGAGCGCCGCCGCGCTTCCGGCTGCTCAGCGCGCTTTCCTATTGCGCACC
GCTGCTCGTCAACGGCATCGTTCTGCCGTTCTTTCCGGTCTGGCTCGCGACCCACAGCTTCAGCGACCACGAGATCGGCA
TCATCCTTGCCATACCGATGGTGGTGCGCGTGCTGGTGGCGCCCGTCGTTGCGATGATCGCCGACCGTCTGAAGGAGCGC
GCCGACGTGCTGCTCTGGTCAGGCAGCCTGTCGCTGCTGACGGCGATCGCGCTTTTCTGGACCACGAGCTTCTGGCCGGT
GACGATCGTCTATGCGCTGCAGGGCGCCACCTTCGCGCCCTATGTGCCCGTCGTCGAATCGATCGTCATTTCGGGCGTGC
GCCGCTGGGGGCTCGATTACGGGTCGATGCGCGTCTGGGGCTCGATTGCCTTCATCGTCTCGACACTGGTCGGTGGCCAG
CTGATCAGCCGTTGGGGCGGTGGATTGGTGCTCGACGTCATGGTGTTCGGCTTTGCCATGACCGTTGTCATGGCGATCTT
CTGTCCGCGCATCGGGCCGACGCGGCGGCGCGGTCAGCCGATCAACATTCCGGCCGCCACCGGCAGCGGACTGCGCGAGC
CGCATTTGCTGCTGCTGTTGATCGGTGTCGCCATCCAGCAGTCGAGCCATGCGGTGCTCAACGCGTTTTCGTCGATCTAC
TGGCATCATCTCGGCTTTTCCGGCACGGAGGTCGGCCTGCTCTGGAGCGCCGGCGTTGCTTCCGAAGTGACGGTGTTCTT
CCTGTCGAAGCGTCTCAACCGGCGCTTCGACGCCTGGACGCTGATCCGCTTCGGCTGTGCCGTCAGCGTCTGCCGCTGGA
TCCTGTTTCCCATGAATGCGGGTTTTGCCGGGTTTTTCCTGCTGCAGTGTTTCCATGGCTTCACTTATGCCTTCGTTCAT
ACCGGCGTGCAGCGGCGGATCATGGCGACGGTGCAGGAGACGCAGGAATCCTCGGCGCAAGGCGCCTACTTCTTCTATGT
CGGCATGGCGATGGCGCTGATGACGCTGGCGTCGGGTTATCTCTATGCCTGGCTCGGCGTCGTCAGCTATTACGTCATGG
CGCTGGTCGCATTCTCCGGCCTCGGTCTGGTCATCTCGGCCTACTACCTTCAGCCCCAGAGCGTGCTTTCGGGCGGAAAG
ACCAGGGAGGCGGCGTAG

Upstream 100 bases:

>100_bases
CCTATTTATTTTCTAAAACGTTTCAGTGTGGCTATTTCTCGCAATAGTCGCCTCCTGGGTGGTGTGTTAGGACAACGACC
AGTTTCCTTCAGGTCCACCA

Downstream 100 bases:

>100_bases
CGCAAGCCGGGTTCGCGGTCGCGGGCAAGCAGCAGCGGGCCGTCGAGATCGACGAAATCGGCATTCTGGGCGAGCAGCAC
CGCCGGCGCCATGGCAAGCG

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MIPAQHSPGEGAPPRFRLLSALSYCAPLLVNGIVLPFFPVWLATHSFSDHEIGIILAIPMVVRVLVAPVVAMIADRLKER
ADVLLWSGSLSLLTAIALFWTTSFWPVTIVYALQGATFAPYVPVVESIVISGVRRWGLDYGSMRVWGSIAFIVSTLVGGQ
LISRWGGGLVLDVMVFGFAMTVVMAIFCPRIGPTRRRGQPINIPAATGSGLREPHLLLLLIGVAIQQSSHAVLNAFSSIY
WHHLGFSGTEVGLLWSAGVASEVTVFFLSKRLNRRFDAWTLIRFGCAVSVCRWILFPMNAGFAGFFLLQCFHGFTYAFVH
TGVQRRIMATVQETQESSAQGAYFFYVGMAMALMTLASGYLYAWLGVVSYYVMALVAFSGLGLVISAYYLQPQSVLSGGK
TREAA

Sequences:

>Translated_405_residues
MIPAQHSPGEGAPPRFRLLSALSYCAPLLVNGIVLPFFPVWLATHSFSDHEIGIILAIPMVVRVLVAPVVAMIADRLKER
ADVLLWSGSLSLLTAIALFWTTSFWPVTIVYALQGATFAPYVPVVESIVISGVRRWGLDYGSMRVWGSIAFIVSTLVGGQ
LISRWGGGLVLDVMVFGFAMTVVMAIFCPRIGPTRRRGQPINIPAATGSGLREPHLLLLLIGVAIQQSSHAVLNAFSSIY
WHHLGFSGTEVGLLWSAGVASEVTVFFLSKRLNRRFDAWTLIRFGCAVSVCRWILFPMNAGFAGFFLLQCFHGFTYAFVH
TGVQRRIMATVQETQESSAQGAYFFYVGMAMALMTLASGYLYAWLGVVSYYVMALVAFSGLGLVISAYYLQPQSVLSGGK
TREAA
>Mature_405_residues
MIPAQHSPGEGAPPRFRLLSALSYCAPLLVNGIVLPFFPVWLATHSFSDHEIGIILAIPMVVRVLVAPVVAMIADRLKER
ADVLLWSGSLSLLTAIALFWTTSFWPVTIVYALQGATFAPYVPVVESIVISGVRRWGLDYGSMRVWGSIAFIVSTLVGGQ
LISRWGGGLVLDVMVFGFAMTVVMAIFCPRIGPTRRRGQPINIPAATGSGLREPHLLLLLIGVAIQQSSHAVLNAFSSIY
WHHLGFSGTEVGLLWSAGVASEVTVFFLSKRLNRRFDAWTLIRFGCAVSVCRWILFPMNAGFAGFFLLQCFHGFTYAFVH
TGVQRRIMATVQETQESSAQGAYFFYVGMAMALMTLASGYLYAWLGVVSYYVMALVAFSGLGLVISAYYLQPQSVLSGGK
TREAA

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=384, Percent_Identity=29.1666666666667, Blast_Score=135, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 44209; Mature: 44209

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPAQHSPGEGAPPRFRLLSALSYCAPLLVNGIVLPFFPVWLATHSFSDHEIGIILAIPM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VVRVLVAPVVAMIADRLKERADVLLWSGSLSLLTAIALFWTTSFWPVTIVYALQGATFAP
HHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
YVPVVESIVISGVRRWGLDYGSMRVWGSIAFIVSTLVGGQLISRWGGGLVLDVMVFGFAM
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TVVMAIFCPRIGPTRRRGQPINIPAATGSGLREPHLLLLLIGVAIQQSSHAVLNAFSSIY
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
WHHLGFSGTEVGLLWSAGVASEVTVFFLSKRLNRRFDAWTLIRFGCAVSVCRWILFPMNA
HHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GFAGFFLLQCFHGFTYAFVHTGVQRRIMATVQETQESSAQGAYFFYVGMAMALMTLASGY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LYAWLGVVSYYVMALVAFSGLGLVISAYYLQPQSVLSGGKTREAA
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MIPAQHSPGEGAPPRFRLLSALSYCAPLLVNGIVLPFFPVWLATHSFSDHEIGIILAIPM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VVRVLVAPVVAMIADRLKERADVLLWSGSLSLLTAIALFWTTSFWPVTIVYALQGATFAP
HHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
YVPVVESIVISGVRRWGLDYGSMRVWGSIAFIVSTLVGGQLISRWGGGLVLDVMVFGFAM
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TVVMAIFCPRIGPTRRRGQPINIPAATGSGLREPHLLLLLIGVAIQQSSHAVLNAFSSIY
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
WHHLGFSGTEVGLLWSAGVASEVTVFFLSKRLNRRFDAWTLIRFGCAVSVCRWILFPMNA
HHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GFAGFFLLQCFHGFTYAFVHTGVQRRIMATVQETQESSAQGAYFFYVGMAMALMTLASGY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LYAWLGVVSYYVMALVAFSGLGLVISAYYLQPQSVLSGGKTREAA
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]