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The map label for this gene is sugE [H]

Identifier: 209549472

GI number: 209549472

Start: 1924530

End: 1924844

Strand: Direct

Name: sugE [H]

Synonym: Rleg2_1878

Alternate gene names: 209549472

Gene position: 1924530-1924844 (Clockwise)

Preceding gene: 209549471

Following gene: 209549480

Centisome position: 42.41

GC content: 62.22

Gene sequence:

>315_bases
ATGGCCTGGTTTCTGCTTTTTCTCGCCGGTCTTTTCGAATGTGGCTGGGCGATCGGCCTTAAATACACCGATGGTTTCAC
GCGGCCGCTGCCGACCGCGTTGACTGTCATATCCATGGTGGTCAGCGTCGTCCTGCTCGGCCTGGCGGTGAAGCACCTGC
CGATCGGCACCGCCTATGCGGTGTGGACCGGTATCGGCACAGTCGGCACCGTGCTCCTCGGCATCTGGCTGCTTGGCGAT
CAGGCAAGTGTCTCCCGCCTTGCCTGCATCATGCTGATCGTCGGCGGCATCGCCGGCCTCAAACTCACGGCCTGA

Upstream 100 bases:

>100_bases
GCCGTCTCCTCACGCATATAGACGTCATCGCAGACGACTGCGGCATCTTACCGATGCAACCGTCGCGGGGACGGCCTCGC
TCTTGAACAAGGAGAGTCGT

Downstream 100 bases:

>100_bases
CGAAGAAAATGCTGCGGGGCATCGCAAATGCCCCGCAGTCTGTGTCGGCTCAGGCTGCCTTGCGGTTATCGACGGAAAAT
GCGCCGGGACCGGAGAAGAA

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MAWFLLFLAGLFECGWAIGLKYTDGFTRPLPTALTVISMVVSVVLLGLAVKHLPIGTAYAVWTGIGTVGTVLLGIWLLGD
QASVSRLACIMLIVGGIAGLKLTA

Sequences:

>Translated_104_residues
MAWFLLFLAGLFECGWAIGLKYTDGFTRPLPTALTVISMVVSVVLLGLAVKHLPIGTAYAVWTGIGTVGTVLLGIWLLGD
QASVSRLACIMLIVGGIAGLKLTA
>Mature_103_residues
AWFLLFLAGLFECGWAIGLKYTDGFTRPLPTALTVISMVVSVVLLGLAVKHLPIGTAYAVWTGIGTVGTVLLGIWLLGDQ
ASVSRLACIMLIVGGIAGLKLTA

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=103, Percent_Identity=58.252427184466, Blast_Score=114, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 10875; Mature: 10744

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWFLLFLAGLFECGWAIGLKYTDGFTRPLPTALTVISMVVSVVLLGLAVKHLPIGTAYA
CHHHHHHHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VWTGIGTVGTVLLGIWLLGDQASVSRLACIMLIVGGIAGLKLTA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure 
AWFLLFLAGLFECGWAIGLKYTDGFTRPLPTALTVISMVVSVVLLGLAVKHLPIGTAYA
HHHHHHHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VWTGIGTVGTVLLGIWLLGDQASVSRLACIMLIVGGIAGLKLTA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]