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The map label for this gene is ppiD [H]

Identifier: 209549414

GI number: 209549414

Start: 1866190

End: 1868082

Strand: Direct

Name: ppiD [H]

Synonym: Rleg2_1820

Alternate gene names: 209549414

Gene position: 1866190-1868082 (Clockwise)

Preceding gene: 209549412

Following gene: 209549415

Centisome position: 41.12

GC content: 63.13

Gene sequence:

>1893_bases
ATGTTCCATATCCTGAGAAGAGCCGCTCAGACTTGGGTCGCCAAGCTGCTGATGCTTCTGCTGGTCGCGTCCTTCGGCAT
CTGGGGCGTCTCCCGGTCGCTGATTACCGGCAGCAACAGCACCACGGTCGTGACCGTCGGCGATCAGCATGTGGACGTCA
ACGAATTCCACCTCGCCTACCAGCGCCAGGTGGCAAGCCTCGGCCAGCAGTTCGGCACGCGTCTCACTCCGGAACAGGCT
CGCGCTTTCGGCGTCGAGCAGCAGGTGCTTGCCCAGCTCGTCGCCGGCGCCTCGCTCGACCAGCTCGCCGAAGACATGAA
CCTCGGCCTGTCCGAAGATCGCCTCGCCCAGCTGATCGCCGACGATCCGGCTTTCAAGGCCGTCAACGGCAAGTTCGATC
GTGAACTCTTCATCTCGCGCCTGCGCAACGCCAATATCCGCCAGGACGATTACATCAAGGAGCGCAGCAAGGTCGCTGTC
CGCAGCCAGGTCGTCGATGCCATCTCGAACGGCTTCACCGCCCCGAAGACGCTGATCGACGCTCTGAAGCTCTATGGCAA
TGAAAGCCGCAGCATCGACTATCTGCTGCTCACCAACGCCAATATCGAGCCGATCAAAGCGCCTGCCGACGACGTGCTGG
CGGCATGGTTCGACGGCGTCAAGCAGCGCTACCAGGCGCCTGAATACCGCAAGCTCGTCTATCTCTCGCTGCAGCCCGCC
GATATCGCCGACGCTGCGACCGTCACCGACGACCAGATCCACGAAGCTTTCGACAAGAGCAAGGACACCTACCGCACGCC
GGAAAGCCGCACCATCGAACAGCTGACTTTCACCAGCAAGGATCTTGCCGTTGCCGCCGAAACGGCGCTGAAGGGCGGCA
CCAGCTTCGACCAGCTGGTCTCCGACCAGGGCAAGACGGCAAGCGACGTGCTGCTCGGCGAATTCACCAAGGACAAGGTT
CCCGACCAGGCCGTTGCCGATGCGGCCTTCGCCGTTTCGAAGGACGGCGGCACGACACCTGTCGTCGAGGGCTCCTTCGG
CTCCGTCATCCTGCGCATCACCAACATCAAGCCGGAAACCACCAAGAATTTCGACGAGGTGAAGGAGGATATCCGCAAGC
AGCTGGCGCTTTCCAATGCCTCGCAGGAGGTGATCAACGTTCATGACCGCATCGAGGATCTGCGCGCCGGCGGCGCCACG
CTCGAGGATATTGCCGGCCAGCTGAAGCTCAAGGCCGTGACCGTCGACGCCGTCGATATGACCGGCGCCGACAAGGACGG
CAAAGAGGTCAAGGATATTCCCGTCAAGCAGCAGTTGCTCGGCGAAGCCTTCAAGACCGAAGTCGGCGTCGATGCGCCGC
CGCTGCCGATCGGCAATGACGGCTATGTCTGGTTCAACGTCCGCGAAATTACCCCGACCCGCGAGCGCCCGGTCGCCGAA
GTGCGCGAAAAGGCGGTCGAAGACTGGACGGCTGAACAGCAGAAGGCCGAACTTGCCAAAAAGGCCGAGGCATTGAAGGC
CGAGGCCGCCAAGGGTACGGCGCTTGCCGATATCGCAACGCCGCTCGGCATCGCCGTTGAAAGCAAGAGCGGCGTTACCC
GCGCCACCGATGATCCGGTGCTTGGCCGCGCCGGCGTCACCGCCGCCTTCTCCGGCCCCGTCGACGCGGTCGCGAGTGCC
GTCGGCGCCGATCCGTCGACGCAGATCCTGATGAAGGTCACCGAGGTCAACAGCGAGCCGACCAGCGACGCGCTGAACAA
CCGCGATGCCCAGATCACCGCCATGGCCAATGCCGCCGGCGACGATATTCTCGATCAGATGGTCAACCTGCTGCAGACGC
AGTACGGCGCTCAGATCAACCAGACGCTCGCCGAGCAGGCGACGCTTCGCTAG

Upstream 100 bases:

>100_bases
TTTCGCGCGACAAACTCTTCATTTCCTGTCGGGTTTGTTCTAAGGAACGTCGAATGTCCGCCCGCGCGCGGCTCAATGAT
ACTGCGAGGTTTGCGTTTCT

Downstream 100 bases:

>100_bases
GAGGCCTTATGACCGATCTGAAGCCGTTCCTGGCCAAGGCCGCAAGCCGCGAGCCGCTGACGCGTGACGAGGCGCGCGCC
GCCTTCGACATTCTGATGTC

Product: peptidyl-prolyl cis-trans isomerase D signal peptide protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MFHILRRAAQTWVAKLLMLLLVASFGIWGVSRSLITGSNSTTVVTVGDQHVDVNEFHLAYQRQVASLGQQFGTRLTPEQA
RAFGVEQQVLAQLVAGASLDQLAEDMNLGLSEDRLAQLIADDPAFKAVNGKFDRELFISRLRNANIRQDDYIKERSKVAV
RSQVVDAISNGFTAPKTLIDALKLYGNESRSIDYLLLTNANIEPIKAPADDVLAAWFDGVKQRYQAPEYRKLVYLSLQPA
DIADAATVTDDQIHEAFDKSKDTYRTPESRTIEQLTFTSKDLAVAAETALKGGTSFDQLVSDQGKTASDVLLGEFTKDKV
PDQAVADAAFAVSKDGGTTPVVEGSFGSVILRITNIKPETTKNFDEVKEDIRKQLALSNASQEVINVHDRIEDLRAGGAT
LEDIAGQLKLKAVTVDAVDMTGADKDGKEVKDIPVKQQLLGEAFKTEVGVDAPPLPIGNDGYVWFNVREITPTRERPVAE
VREKAVEDWTAEQQKAELAKKAEALKAEAAKGTALADIATPLGIAVESKSGVTRATDDPVLGRAGVTAAFSGPVDAVASA
VGADPSTQILMKVTEVNSEPTSDALNNRDAQITAMANAAGDDILDQMVNLLQTQYGAQINQTLAEQATLR

Sequences:

>Translated_630_residues
MFHILRRAAQTWVAKLLMLLLVASFGIWGVSRSLITGSNSTTVVTVGDQHVDVNEFHLAYQRQVASLGQQFGTRLTPEQA
RAFGVEQQVLAQLVAGASLDQLAEDMNLGLSEDRLAQLIADDPAFKAVNGKFDRELFISRLRNANIRQDDYIKERSKVAV
RSQVVDAISNGFTAPKTLIDALKLYGNESRSIDYLLLTNANIEPIKAPADDVLAAWFDGVKQRYQAPEYRKLVYLSLQPA
DIADAATVTDDQIHEAFDKSKDTYRTPESRTIEQLTFTSKDLAVAAETALKGGTSFDQLVSDQGKTASDVLLGEFTKDKV
PDQAVADAAFAVSKDGGTTPVVEGSFGSVILRITNIKPETTKNFDEVKEDIRKQLALSNASQEVINVHDRIEDLRAGGAT
LEDIAGQLKLKAVTVDAVDMTGADKDGKEVKDIPVKQQLLGEAFKTEVGVDAPPLPIGNDGYVWFNVREITPTRERPVAE
VREKAVEDWTAEQQKAELAKKAEALKAEAAKGTALADIATPLGIAVESKSGVTRATDDPVLGRAGVTAAFSGPVDAVASA
VGADPSTQILMKVTEVNSEPTSDALNNRDAQITAMANAAGDDILDQMVNLLQTQYGAQINQTLAEQATLR
>Mature_630_residues
MFHILRRAAQTWVAKLLMLLLVASFGIWGVSRSLITGSNSTTVVTVGDQHVDVNEFHLAYQRQVASLGQQFGTRLTPEQA
RAFGVEQQVLAQLVAGASLDQLAEDMNLGLSEDRLAQLIADDPAFKAVNGKFDRELFISRLRNANIRQDDYIKERSKVAV
RSQVVDAISNGFTAPKTLIDALKLYGNESRSIDYLLLTNANIEPIKAPADDVLAAWFDGVKQRYQAPEYRKLVYLSLQPA
DIADAATVTDDQIHEAFDKSKDTYRTPESRTIEQLTFTSKDLAVAAETALKGGTSFDQLVSDQGKTASDVLLGEFTKDKV
PDQAVADAAFAVSKDGGTTPVVEGSFGSVILRITNIKPETTKNFDEVKEDIRKQLALSNASQEVINVHDRIEDLRAGGAT
LEDIAGQLKLKAVTVDAVDMTGADKDGKEVKDIPVKQQLLGEAFKTEVGVDAPPLPIGNDGYVWFNVREITPTRERPVAE
VREKAVEDWTAEQQKAELAKKAEALKAEAAKGTALADIATPLGIAVESKSGVTRATDDPVLGRAGVTAAFSGPVDAVASA
VGADPSTQILMKVTEVNSEPTSDALNNRDAQITAMANAAGDDILDQMVNLLQTQYGAQINQTLAEQATLR

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=576, Percent_Identity=23.9583333333333, Blast_Score=129, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68022; Mature: 68022

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHILRRAAQTWVAKLLMLLLVASFGIWGVSRSLITGSNSTTVVTVGDQHVDVNEFHLAY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCEEEEEECCCCCCHHHHHHHH
QRQVASLGQQFGTRLTPEQARAFGVEQQVLAQLVAGASLDQLAEDMNLGLSEDRLAQLIA
HHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHH
DDPAFKAVNGKFDRELFISRLRNANIRQDDYIKERSKVAVRSQVVDAISNGFTAPKTLID
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALKLYGNESRSIDYLLLTNANIEPIKAPADDVLAAWFDGVKQRYQAPEYRKLVYLSLQPA
HHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
DIADAATVTDDQIHEAFDKSKDTYRTPESRTIEQLTFTSKDLAVAAETALKGGTSFDQLV
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCHHHHH
SDQGKTASDVLLGEFTKDKVPDQAVADAAFAVSKDGGTTPVVEGSFGSVILRITNIKPET
HCCCCCHHHHHHHCCHHCCCCCHHHHHHHHEEECCCCCCCEEECCCCEEEEEEECCCCCC
TKNFDEVKEDIRKQLALSNASQEVINVHDRIEDLRAGGATLEDIAGQLKLKAVTVDAVDM
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCEEEEEEEEEEEEC
TGADKDGKEVKDIPVKQQLLGEAFKTEVGVDAPPLPIGNDGYVWFNVREITPTRERPVAE
CCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHH
VREKAVEDWTAEQQKAELAKKAEALKAEAAKGTALADIATPLGIAVESKSGVTRATDDPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEECCCCCCCCCCCCC
LGRAGVTAAFSGPVDAVASAVGADPSTQILMKVTEVNSEPTSDALNNRDAQITAMANAAG
CCCCCCCEECCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHCCCCCEEEEECCCCC
DDILDQMVNLLQTQYGAQINQTLAEQATLR
HHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure
MFHILRRAAQTWVAKLLMLLLVASFGIWGVSRSLITGSNSTTVVTVGDQHVDVNEFHLAY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCEEEEEECCCCCCHHHHHHHH
QRQVASLGQQFGTRLTPEQARAFGVEQQVLAQLVAGASLDQLAEDMNLGLSEDRLAQLIA
HHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHH
DDPAFKAVNGKFDRELFISRLRNANIRQDDYIKERSKVAVRSQVVDAISNGFTAPKTLID
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALKLYGNESRSIDYLLLTNANIEPIKAPADDVLAAWFDGVKQRYQAPEYRKLVYLSLQPA
HHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
DIADAATVTDDQIHEAFDKSKDTYRTPESRTIEQLTFTSKDLAVAAETALKGGTSFDQLV
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCHHHHH
SDQGKTASDVLLGEFTKDKVPDQAVADAAFAVSKDGGTTPVVEGSFGSVILRITNIKPET
HCCCCCHHHHHHHCCHHCCCCCHHHHHHHHEEECCCCCCCEEECCCCEEEEEEECCCCCC
TKNFDEVKEDIRKQLALSNASQEVINVHDRIEDLRAGGATLEDIAGQLKLKAVTVDAVDM
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCEEEEEEEEEEEEC
TGADKDGKEVKDIPVKQQLLGEAFKTEVGVDAPPLPIGNDGYVWFNVREITPTRERPVAE
CCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHH
VREKAVEDWTAEQQKAELAKKAEALKAEAAKGTALADIATPLGIAVESKSGVTRATDDPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEECCCCCCCCCCCCC
LGRAGVTAAFSGPVDAVASAVGADPSTQILMKVTEVNSEPTSDALNNRDAQITAMANAAG
CCCCCCCEECCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHCCCCCEEEEECCCCC
DDILDQMVNLLQTQYGAQINQTLAEQATLR
HHHHHHHHHHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]