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The map label for this gene is tig [H]

Identifier: 209549106

GI number: 209549106

Start: 1537046

End: 1538533

Strand: Direct

Name: tig [H]

Synonym: Rleg2_1505

Alternate gene names: 209549106

Gene position: 1537046-1538533 (Clockwise)

Preceding gene: 209549105

Following gene: 209549107

Centisome position: 33.87

GC content: 60.95

Gene sequence:

>1488_bases
ATGCAGGTTATCGAAACGCTCGCTGAAGGGCTGAAGCGCGAAATCAAGGTCGTTATCCCGGCCAAGGACATGCAAGACAA
GATGAATGAGCGTCTTGCCGATGTGAAGGACAAGGTCCGCATCAACGGCTTCCGTCCGGGCAAGGTACCCGCTGCTCACC
TGAAGAAGGTCTACGGCAAGTCGATCATGGCCGAACTCGTCAACGAGATCGTCCGCGAGCAGCCGTCGGCCATCCTCTCC
AGCCGCGGCGAAAAGTCGGCCACGCAGCCGGAAATCGCCATGACCGAGGACAAGGACGAAGCCGACAAGATCCTCGCCGC
CGAGCAGGATTTCGAATTCACGCTCTCCTATGAAGTGCTGCCGCCGATCGAACTGAAGTCGGTCAAGGGCATCAAGGTCA
CGCGCGAAGTCATCGACATCTCGGACGACGAAGTCACCGAGCAGGTCCTGAAGGTCGCCGAAAGCGCCCGCGCTTACGAG
ACCAAGACCGGCAAGGCCGCCAACGGCGACCGCATCACCATGGATTACCTCGGCAAGGTCGACGGCGAAGCCTTTGAAGG
CGGCACCGACCAGGGCGCCGAACTGGTGCTCGGCTCCGGCCGCTTCATTCCGGGCTTCGAAGACCAGCTCGTCGGCGTCA
AGGCCGGCGACGAGAAGACCATCACCGTGACCTTCCCGGCCGACTATCCGGCCAAGAACCTCGCCGGCAAGGAAGCCACC
TTCGACGTATCGGTCAAGGATGTTGCAGCCCCCGGCGCCGTCGAGATCAATGACGAACTCGCCTCCAAGCTCGGCATCGA
ATCCGCCGATCGCCTGAAGGAAATCGTCCGCGGCCAGATCGAATCGCAGTACGGTTCGCTGACCCGCCAGAAGCTGAAGC
GCCAGATCCTCGACCAGCTCGACGAGATGTACAAGTTCGAGACCCCGACCTCGCTCGTCGACGCCGAATATAACGGCATC
TGGAGCCAGGTGAACAACGACCTCGCTCAATCCGGCAAGACCTTCGAGGACGAAGAGACGACCGAAGAGAAGGCACGTGA
GGAATACAAGACGCTTGCAGAGCGTCGCGTCCGCCTCGGCCTCGTTCTCTCCGAAATCGGCGAAAAGGCCGGCGTCGAAG
TCACCGAAGACGAGATGCAGCGCGCCATCTACGATCAGCTGCGCCAGTATCCGGGTCAGGAAAAGCAGATCCTCGAATTC
TTCCGCAGCCAGCCGGGCGCCGCAGCTTCGATCCGCGCGCCGATCTTCGAAGAGAAGGTCATCGATCATCTGCTGACCGA
AATCGACGTCACCGACAAGAAGGTGACCAAGGAAGAACTGCTCGCCGAGGAAGAAGGCGAGGCGAAGGCTGAAACCAAGA
AGGCCGCCCCGAAGAAGAAGGCCGCCGCCAAGGCTGAAGCTGCCGACGCCGGCGAAGGCGAAGAAGCCGCCGCTCCGAAG
AAGAAGGCCGCTCCGAAGAAGAAGGCAGCCGACGAAAGCGCCGAATAA

Upstream 100 bases:

>100_bases
CAGGAATTGGGAAAAGCCACGCGCGGCACGCTGCCGGCGTCGTGCTCATTGAAACGAACGGCGTCTGGGCACGGCCGCCA
GGACATGAAGGTAGGAAGAC

Downstream 100 bases:

>100_bases
TCGCTTCCTGGTTCTGATGTTTGAAGGCCCCGCCATCGTGCGGGGCCTTTTCTATTGCGGGCATCCGGCAGTCCCCCGTC
TTCATCCGCAACAACAAATA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MQVIETLAEGLKREIKVVIPAKDMQDKMNERLADVKDKVRINGFRPGKVPAAHLKKVYGKSIMAELVNEIVREQPSAILS
SRGEKSATQPEIAMTEDKDEADKILAAEQDFEFTLSYEVLPPIELKSVKGIKVTREVIDISDDEVTEQVLKVAESARAYE
TKTGKAANGDRITMDYLGKVDGEAFEGGTDQGAELVLGSGRFIPGFEDQLVGVKAGDEKTITVTFPADYPAKNLAGKEAT
FDVSVKDVAAPGAVEINDELASKLGIESADRLKEIVRGQIESQYGSLTRQKLKRQILDQLDEMYKFETPTSLVDAEYNGI
WSQVNNDLAQSGKTFEDEETTEEKAREEYKTLAERRVRLGLVLSEIGEKAGVEVTEDEMQRAIYDQLRQYPGQEKQILEF
FRSQPGAAASIRAPIFEEKVIDHLLTEIDVTDKKVTKEELLAEEEGEAKAETKKAAPKKKAAAKAEAADAGEGEEAAAPK
KKAAPKKKAADESAE

Sequences:

>Translated_495_residues
MQVIETLAEGLKREIKVVIPAKDMQDKMNERLADVKDKVRINGFRPGKVPAAHLKKVYGKSIMAELVNEIVREQPSAILS
SRGEKSATQPEIAMTEDKDEADKILAAEQDFEFTLSYEVLPPIELKSVKGIKVTREVIDISDDEVTEQVLKVAESARAYE
TKTGKAANGDRITMDYLGKVDGEAFEGGTDQGAELVLGSGRFIPGFEDQLVGVKAGDEKTITVTFPADYPAKNLAGKEAT
FDVSVKDVAAPGAVEINDELASKLGIESADRLKEIVRGQIESQYGSLTRQKLKRQILDQLDEMYKFETPTSLVDAEYNGI
WSQVNNDLAQSGKTFEDEETTEEKAREEYKTLAERRVRLGLVLSEIGEKAGVEVTEDEMQRAIYDQLRQYPGQEKQILEF
FRSQPGAAASIRAPIFEEKVIDHLLTEIDVTDKKVTKEELLAEEEGEAKAETKKAAPKKKAAAKAEAADAGEGEEAAAPK
KKAAPKKKAADESAE
>Mature_495_residues
MQVIETLAEGLKREIKVVIPAKDMQDKMNERLADVKDKVRINGFRPGKVPAAHLKKVYGKSIMAELVNEIVREQPSAILS
SRGEKSATQPEIAMTEDKDEADKILAAEQDFEFTLSYEVLPPIELKSVKGIKVTREVIDISDDEVTEQVLKVAESARAYE
TKTGKAANGDRITMDYLGKVDGEAFEGGTDQGAELVLGSGRFIPGFEDQLVGVKAGDEKTITVTFPADYPAKNLAGKEAT
FDVSVKDVAAPGAVEINDELASKLGIESADRLKEIVRGQIESQYGSLTRQKLKRQILDQLDEMYKFETPTSLVDAEYNGI
WSQVNNDLAQSGKTFEDEETTEEKAREEYKTLAERRVRLGLVLSEIGEKAGVEVTEDEMQRAIYDQLRQYPGQEKQILEF
FRSQPGAAASIRAPIFEEKVIDHLLTEIDVTDKKVTKEELLAEEEGEAKAETKKAAPKKKAAAKAEAADAGEGEEAAAPK
KKAAPKKKAADESAE

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=447, Percent_Identity=30.4250559284116, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 54442; Mature: 54442

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVIETLAEGLKREIKVVIPAKDMQDKMNERLADVKDKVRINGFRPGKVPAAHLKKVYGK
CHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHH
SIMAELVNEIVREQPSAILSSRGEKSATQPEIAMTEDKDEADKILAAEQDFEFTLSYEVL
HHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHCCCCCEEEEEEECC
PPIELKSVKGIKVTREVIDISDDEVTEQVLKVAESARAYETKTGKAANGDRITMDYLGKV
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHCC
DGEAFEGGTDQGAELVLGSGRFIPGFEDQLVGVKAGDEKTITVTFPADYPAKNLAGKEAT
CCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCEEEEEEECCCCCHHHCCCCCCE
FDVSVKDVAAPGAVEINDELASKLGIESADRLKEIVRGQIESQYGSLTRQKLKRQILDQL
EEEEHHHHCCCCCEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEMYKFETPTSLVDAEYNGIWSQVNNDLAQSGKTFEDEETTEEKAREEYKTLAERRVRLG
HHHHHCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVLSEIGEKAGVEVTEDEMQRAIYDQLRQYPGQEKQILEFFRSQPGAAASIRAPIFEEKV
HHHHHHHHHCCCEECHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHH
IDHLLTEIDVTDKKVTKEELLAEEEGEAKAETKKAAPKKKAAAKAEAADAGEGEEAAAPK
HHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCHHCCCC
KKAAPKKKAADESAE
HHCCCCHHCCCCCCC
>Mature Secondary Structure
MQVIETLAEGLKREIKVVIPAKDMQDKMNERLADVKDKVRINGFRPGKVPAAHLKKVYGK
CHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHH
SIMAELVNEIVREQPSAILSSRGEKSATQPEIAMTEDKDEADKILAAEQDFEFTLSYEVL
HHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHCCCCCEEEEEEECC
PPIELKSVKGIKVTREVIDISDDEVTEQVLKVAESARAYETKTGKAANGDRITMDYLGKV
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHCC
DGEAFEGGTDQGAELVLGSGRFIPGFEDQLVGVKAGDEKTITVTFPADYPAKNLAGKEAT
CCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCEEEEEEECCCCCHHHCCCCCCE
FDVSVKDVAAPGAVEINDELASKLGIESADRLKEIVRGQIESQYGSLTRQKLKRQILDQL
EEEEHHHHCCCCCEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEMYKFETPTSLVDAEYNGIWSQVNNDLAQSGKTFEDEETTEEKAREEYKTLAERRVRLG
HHHHHCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVLSEIGEKAGVEVTEDEMQRAIYDQLRQYPGQEKQILEFFRSQPGAAASIRAPIFEEKV
HHHHHHHHHCCCEECHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHH
IDHLLTEIDVTDKKVTKEELLAEEEGEAKAETKKAAPKKKAAAKAEAADAGEGEEAAAPK
HHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCHHCCCC
KKAAPKKKAADESAE
HHCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA