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The map label for this gene is yhcK [H]

Identifier: 209549026

GI number: 209549026

Start: 1447352

End: 1448626

Strand: Direct

Name: yhcK [H]

Synonym: Rleg2_1423

Alternate gene names: 209549026

Gene position: 1447352-1448626 (Clockwise)

Preceding gene: 209549025

Following gene: 209549027

Centisome position: 31.89

GC content: 61.41

Gene sequence:

>1275_bases
ATGGTGATGGAGACGCTCAACCTCGCTCTTTTCGTCGTCGAAGCCGTCGCCTATTTCGTGCTGATGGTGACGCTTCTGCA
TTTCCGTCATCGGCTCGGGCTCGGGGTTTTCCTGACGGCGCTCGGCGTCATGCATTTCATGGAAACCTATCTGGCGGCGG
TCTTCTATGTCTCGCTGCCGTTCGGCGATGTGTCGCCGGGCTCGTCGGTCTTCTTCTCCGGCAAGTTGATGATGATCCTG
ATGCTTTACCGGCAGGAGGATGCCGCGACGGTGCGCCAGCCGATCTATGGCCTGTTCCTTGGTAACCTGCTCACCGTCGG
CATTGCCTGGGTGCTGCAGCTGCACCTGCCGCTGCAGATGTCGCCCGCCCACACGCCTGATGTCGATTTCCTGCAGGAGA
TGGGCTGGCTGATGGTCTGGGGCACGGCGCTGCTCTATGTCGATTCGCTCGGCATCATTCTGCTTTACGAAAAGCTCGGC
GATTTCTTCCGTCGGCGCGTCGTCCTGCGTTTCCTGATTTCGGGCTTCGTGCTGCTGACCTTCGACCAGATCGGCTTCTT
TGCCGCGCTGCATTATTTTCTGGACGTGCCGATCGCCGCATTCTGGGCAGGTTGGAAGGCGAAAATGCTTGCCGTCTGCC
TCTATGCGGCAATGTTTGCAATCTATGAATATCGTATTCGCCGCGGCGGCAAGGCCGTCTCCGCGCGTTCGATCAGCGAC
GTGTTCGGCGACCTGACGTTCCGCGAGCGCTACAACGATCTTCTGGAGCGTACCGGACGCGACATGCTGACCGGCGTCTA
TGACCGGACGCGCATGGAGGTGGAGGCGCCGCTGATGATGCGTGAGGCGCTGAGGCAGGGTCTCTACGCCACGGTGCTCA
TCATCGATGCCGATCACTTCAAGGATGTCAACGACGGCTATGGGCATCTTCAGGGTGACGAGGTGCTGAAGGCGATCGCC
GCCCGGCTCGGTACGACGCTACGCTCGAGCGACCGCATCTTCCGCTTCGGCGGCGAGGAATTCGTCGCCGTCTGCCCCGG
CACCGATCACGAGGAAGCTTTGCTGCTGGCCGAACGGCTGCGCTGGACGATCGCCACCAGCGTCAAGACGCCGGATGACA
AGCCGGTGACGGTCAGCATCGGCGTGGCGACAGCCGACGAGGACGGCGTCGATTTCACCGCCGTGCTCACGGCTGCGGAC
GGCAGGCTCTACGCGGCAAAGAAGAGTGGCCGCAATTGTGTCGTCGGCCGTTCCGGTGTCGTGAAACTCGGTTGA

Upstream 100 bases:

>100_bases
CCGCCCTCGTGTTTGACTTTTTCGGACAATCGACCAAAGCATCCGCTGTCGCGACCGTTGCGCCCGCGTTCCGTCCAGGG
CGCCGGCCTGAAGCCGGGGT

Downstream 100 bases:

>100_bases
CCCGATCAATGCAGTGCGTTGGTTGCCGGTGTTTGTGATGTTGCATAAAGCAAAACATCTGCCGCCAACATCATTATTTT
TCAATATGTTATAAGGACAA

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MVMETLNLALFVVEAVAYFVLMVTLLHFRHRLGLGVFLTALGVMHFMETYLAAVFYVSLPFGDVSPGSSVFFSGKLMMIL
MLYRQEDAATVRQPIYGLFLGNLLTVGIAWVLQLHLPLQMSPAHTPDVDFLQEMGWLMVWGTALLYVDSLGIILLYEKLG
DFFRRRVVLRFLISGFVLLTFDQIGFFAALHYFLDVPIAAFWAGWKAKMLAVCLYAAMFAIYEYRIRRGGKAVSARSISD
VFGDLTFRERYNDLLERTGRDMLTGVYDRTRMEVEAPLMMREALRQGLYATVLIIDADHFKDVNDGYGHLQGDEVLKAIA
ARLGTTLRSSDRIFRFGGEEFVAVCPGTDHEEALLLAERLRWTIATSVKTPDDKPVTVSIGVATADEDGVDFTAVLTAAD
GRLYAAKKSGRNCVVGRSGVVKLG

Sequences:

>Translated_424_residues
MVMETLNLALFVVEAVAYFVLMVTLLHFRHRLGLGVFLTALGVMHFMETYLAAVFYVSLPFGDVSPGSSVFFSGKLMMIL
MLYRQEDAATVRQPIYGLFLGNLLTVGIAWVLQLHLPLQMSPAHTPDVDFLQEMGWLMVWGTALLYVDSLGIILLYEKLG
DFFRRRVVLRFLISGFVLLTFDQIGFFAALHYFLDVPIAAFWAGWKAKMLAVCLYAAMFAIYEYRIRRGGKAVSARSISD
VFGDLTFRERYNDLLERTGRDMLTGVYDRTRMEVEAPLMMREALRQGLYATVLIIDADHFKDVNDGYGHLQGDEVLKAIA
ARLGTTLRSSDRIFRFGGEEFVAVCPGTDHEEALLLAERLRWTIATSVKTPDDKPVTVSIGVATADEDGVDFTAVLTAAD
GRLYAAKKSGRNCVVGRSGVVKLG
>Mature_424_residues
MVMETLNLALFVVEAVAYFVLMVTLLHFRHRLGLGVFLTALGVMHFMETYLAAVFYVSLPFGDVSPGSSVFFSGKLMMIL
MLYRQEDAATVRQPIYGLFLGNLLTVGIAWVLQLHLPLQMSPAHTPDVDFLQEMGWLMVWGTALLYVDSLGIILLYEKLG
DFFRRRVVLRFLISGFVLLTFDQIGFFAALHYFLDVPIAAFWAGWKAKMLAVCLYAAMFAIYEYRIRRGGKAVSARSISD
VFGDLTFRERYNDLLERTGRDMLTGVYDRTRMEVEAPLMMREALRQGLYATVLIIDADHFKDVNDGYGHLQGDEVLKAIA
ARLGTTLRSSDRIFRFGGEEFVAVCPGTDHEEALLLAERLRWTIATSVKTPDDKPVTVSIGVATADEDGVDFTAVLTAAD
GRLYAAKKSGRNCVVGRSGVVKLG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=155, Percent_Identity=41.2903225806452, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787262, Length=168, Percent_Identity=37.5, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=36.0759493670886, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=38.5474860335196, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI87082007, Length=159, Percent_Identity=37.1069182389937, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1787802, Length=162, Percent_Identity=35.8024691358025, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=33.9622641509434, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788381, Length=206, Percent_Identity=27.1844660194175, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787541, Length=163, Percent_Identity=30.6748466257669, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788085, Length=162, Percent_Identity=30.8641975308642, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787056, Length=121, Percent_Identity=36.3636363636364, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87081974, Length=159, Percent_Identity=26.4150943396226, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 47344; Mature: 47344

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EECC
>Mature Secondary Structure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EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]