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The map label for this gene is gpt [H]

Identifier: 209549018

GI number: 209549018

Start: 1438901

End: 1439395

Strand: Reverse

Name: gpt [H]

Synonym: Rleg2_1415

Alternate gene names: 209549018

Gene position: 1439395-1438901 (Counterclockwise)

Preceding gene: 209549019

Following gene: 209549017

Centisome position: 31.72

GC content: 62.22

Gene sequence:

>495_bases
ATGTCCCTTCCCGATAAAGCCTTTCCCGTTTCCTGGGATCAGTTCCACCGCGATGCGCGCGCCCTTGCCTGGCGGCTTGC
CGGCCTCGATCAGACGTTCAAGGCGATCGTCTGCATCACCCGCGGCGGCCTCGTTCCGGCCGCGATCATCTCGCGCGAAC
TGAACATCCGGCTGATCGAGACCGTCTGCGTCGCCTCCTATCATGACTATGTGAACCAGGGCGACATGACGCTGCTCAAG
GGAATAGCGCCGGAGCTTGCCGAAAACGGCGGCGAAGGCGTGCTCGTCGTCGACGATCTGACCGATACCGGCAAGACCGC
CGTCCAGGTGCGCACCATGCTGCCGCAGGCCCATTTCGCCTGCGTCTATGCCAAGCCGAAGGGTGTTCCTACCATCGATA
CCTTCATCACCGAGGTGAGCCAGGATACCTGGATCTACTTCCCTTGGGACATGGGCTTCACCTACCAGGAGCCGATCGCC
AAGGGCGCCCGCTGA

Upstream 100 bases:

>100_bases
GTTGCAACTCGCGCGATTTCTTGTTTTGCCGATCGCCGCCTCAAGCCCCTCCGGTCGCCGGCAAACGGCGTGTTGATTTT
TCATGCCGCGGAGCAGCCCG

Downstream 100 bases:

>100_bases
TCGCCGATCAGAGCGCGTGATCCTCGTATTTACCACTTGAAATTGTTCCAGATTTTGTCTGCGGATTTCGCGAATCCGCT
ATCGGGATTCACACATCTAT

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MSLPDKAFPVSWDQFHRDARALAWRLAGLDQTFKAIVCITRGGLVPAAIISRELNIRLIETVCVASYHDYVNQGDMTLLK
GIAPELAENGGEGVLVVDDLTDTGKTAVQVRTMLPQAHFACVYAKPKGVPTIDTFITEVSQDTWIYFPWDMGFTYQEPIA
KGAR

Sequences:

>Translated_164_residues
MSLPDKAFPVSWDQFHRDARALAWRLAGLDQTFKAIVCITRGGLVPAAIISRELNIRLIETVCVASYHDYVNQGDMTLLK
GIAPELAENGGEGVLVVDDLTDTGKTAVQVRTMLPQAHFACVYAKPKGVPTIDTFITEVSQDTWIYFPWDMGFTYQEPIA
KGAR
>Mature_163_residues
SLPDKAFPVSWDQFHRDARALAWRLAGLDQTFKAIVCITRGGLVPAAIISRELNIRLIETVCVASYHDYVNQGDMTLLKG
IAPELAENGGEGVLVVDDLTDTGKTAVQVRTMLPQAHFACVYAKPKGVPTIDTFITEVSQDTWIYFPWDMGFTYQEPIAK
GAR

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=155, Percent_Identity=47.0967741935484, Blast_Score=150, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 18146; Mature: 18015

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00847 MCM_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPDKAFPVSWDQFHRDARALAWRLAGLDQTFKAIVCITRGGLVPAAIISRELNIRLIE
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCCCHHHHHHCCCCEEEHH
TVCVASYHDYVNQGDMTLLKGIAPELAENGGEGVLVVDDLTDTGKTAVQVRTMLPQAHFA
HHHHHHHHHHHCCCCHHHHHHCCHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEE
CVYAKPKGVPTIDTFITEVSQDTWIYFPWDMGFTYQEPIAKGAR
EEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCC
>Mature Secondary Structure 
SLPDKAFPVSWDQFHRDARALAWRLAGLDQTFKAIVCITRGGLVPAAIISRELNIRLIE
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCCCHHHHHHCCCCEEEHH
TVCVASYHDYVNQGDMTLLKGIAPELAENGGEGVLVVDDLTDTGKTAVQVRTMLPQAHFA
HHHHHHHHHHHCCCCHHHHHHCCHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEE
CVYAKPKGVPTIDTFITEVSQDTWIYFPWDMGFTYQEPIAKGAR
EEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA