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The map label for this gene is bioH [C]

Identifier: 209548970

GI number: 209548970

Start: 1385893

End: 1386825

Strand: Direct

Name: bioH [C]

Synonym: Rleg2_1367

Alternate gene names: 209548970

Gene position: 1385893-1386825 (Clockwise)

Preceding gene: 209548968

Following gene: 209548972

Centisome position: 30.54

GC content: 64.09

Gene sequence:

>933_bases
ATGAGGCTGATTTCGATGATCGCAACCGCTGCCGCATTCCTGGCCGCGCCCGATATGGCGGGCGCCGGCGGCGCGCCGGC
GAGCGAGGATAAGGCGGTCGCGCCGATCGTCAGGAAGGGAAGCGTGCCGGTCAACGGTATCGACTATTATTACGAAATCC
GCGGGGAGGGCGAACCGCTGCTGCTTTTGCACGGCGGCCTCGGGCAGATCGAGATGTTCGCGCCGGTCATGCCCGTTTTC
GCGGACCACCGGCAGGTGATCGCCGTCGATCTGCAGGGCCATGGCCGCACGCCGCTCGGCAATCGGCCGATCGACCTTGC
GGCAATCGGCGCCGATCTCGCAATCCTGGTGAAGCAACTCGGCTACGACAAGCTCGACGTCTTCGGTTATTCCTTCGGCG
GCGGAGTGGCGCTGAACATGGCGGCGAATGCACCCGACCAGGTGCGCCGCCTGGTGATCCTCTCGGCGCCCTATGCGCAG
AACGGCTTCTTCCCGGAGATGCTGCCGCAGCAGGCGGCCGTCGGCGCCGGCATGGCCGAGATGATGAAGGACACGCCGAT
GTTCCTCTCCTACAAGGCGGTGGCGCCCGACGTGTCCGAATTTCCGAAGCTGCTCGACGCCATGGGTGCGCTGATGCGCG
AACCCAAGGATTATAGCGATGCCGTCGCCAAGCTCACCATGCCCGTGATGCTGATCTATGGCGACGCCGATATGATCCGC
CCCGAGCATATAATCGACTTCTATCACAAGCTCGGCGGCGGTCTGCGCGATGCGGGCTGGATGCGGGAGAACATGTCGAA
GAACCGGCTGGCGATCCTGCCGGATCTCACTCACTACGAGACCTTCGCTTCGCCGCTCATGGCGAACGTGGCGATGACTT
TCCTCGATGGCGGCGGCAAGACGCCGAACTGGGCCGAGCAGGTCGGCAAATGA

Upstream 100 bases:

>100_bases
AACGCCCGATCGGAGAAATTTCGAAGTGTAGTGTCGGGAAAGCCTGGCCGTCGCCGTCCTTGCGGTATCGATGCAAAAAC
GGAGCAAGGACATGTCGAAG

Downstream 100 bases:

>100_bases
AGTGAGGCGGTCGGCCTTCTGGTCACGAGCGAACCTGCGCCGCACCCCGATATCCGGAAAGCGGCGCAGGTTATAGTCTT
GGGTATCAGGCCGAGGCCGT

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: SEH; Cytosolic epoxide hydrolase; cEH; Epoxide hydratase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MRLISMIATAAAFLAAPDMAGAGGAPASEDKAVAPIVRKGSVPVNGIDYYYEIRGEGEPLLLLHGGLGQIEMFAPVMPVF
ADHRQVIAVDLQGHGRTPLGNRPIDLAAIGADLAILVKQLGYDKLDVFGYSFGGGVALNMAANAPDQVRRLVILSAPYAQ
NGFFPEMLPQQAAVGAGMAEMMKDTPMFLSYKAVAPDVSEFPKLLDAMGALMREPKDYSDAVAKLTMPVMLIYGDADMIR
PEHIIDFYHKLGGGLRDAGWMRENMSKNRLAILPDLTHYETFASPLMANVAMTFLDGGGKTPNWAEQVGK

Sequences:

>Translated_310_residues
MRLISMIATAAAFLAAPDMAGAGGAPASEDKAVAPIVRKGSVPVNGIDYYYEIRGEGEPLLLLHGGLGQIEMFAPVMPVF
ADHRQVIAVDLQGHGRTPLGNRPIDLAAIGADLAILVKQLGYDKLDVFGYSFGGGVALNMAANAPDQVRRLVILSAPYAQ
NGFFPEMLPQQAAVGAGMAEMMKDTPMFLSYKAVAPDVSEFPKLLDAMGALMREPKDYSDAVAKLTMPVMLIYGDADMIR
PEHIIDFYHKLGGGLRDAGWMRENMSKNRLAILPDLTHYETFASPLMANVAMTFLDGGGKTPNWAEQVGK
>Mature_310_residues
MRLISMIATAAAFLAAPDMAGAGGAPASEDKAVAPIVRKGSVPVNGIDYYYEIRGEGEPLLLLHGGLGQIEMFAPVMPVF
ADHRQVIAVDLQGHGRTPLGNRPIDLAAIGADLAILVKQLGYDKLDVFGYSFGGGVALNMAANAPDQVRRLVILSAPYAQ
NGFFPEMLPQQAAVGAGMAEMMKDTPMFLSYKAVAPDVSEFPKLLDAMGALMREPKDYSDAVAKLTMPVMLIYGDADMIR
PEHIIDFYHKLGGGLRDAGWMRENMSKNRLAILPDLTHYETFASPLMANVAMTFLDGGGKTPNWAEQVGK

Specific function: Involved in catabolic degradation of epoxides. Shows highest activity towards C6 and C7 carbocyclic epoxides. Also active towards linear 1,2-epoxyalkanes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR010497 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF06441 EHN [H]

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 33299; Mature: 33299

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLISMIATAAAFLAAPDMAGAGGAPASEDKAVAPIVRKGSVPVNGIDYYYEIRGEGEPL
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEEECCCCEE
LLLHGGLGQIEMFAPVMPVFADHRQVIAVDLQGHGRTPLGNRPIDLAAIGADLAILVKQL
EEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEHEEHHHHHHHHHHHH
GYDKLDVFGYSFGGGVALNMAANAPDQVRRLVILSAPYAQNGFFPEMLPQQAAVGAGMAE
CCCEEEEEEEECCCCEEEEECCCCHHHHEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHH
MMKDTPMFLSYKAVAPDVSEFPKLLDAMGALMREPKDYSDAVAKLTMPVMLIYGDADMIR
HHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEEECCCHHCC
PEHIIDFYHKLGGGLRDAGWMRENMSKNRLAILPDLTHYETFASPLMANVAMTFLDGGGK
HHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
TPNWAEQVGK
CCCHHHHHCC
>Mature Secondary Structure
MRLISMIATAAAFLAAPDMAGAGGAPASEDKAVAPIVRKGSVPVNGIDYYYEIRGEGEPL
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEEECCCCEE
LLLHGGLGQIEMFAPVMPVFADHRQVIAVDLQGHGRTPLGNRPIDLAAIGADLAILVKQL
EEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEHEEHHHHHHHHHHHH
GYDKLDVFGYSFGGGVALNMAANAPDQVRRLVILSAPYAQNGFFPEMLPQQAAVGAGMAE
CCCEEEEEEEECCCCEEEEECCCCHHHHEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHH
MMKDTPMFLSYKAVAPDVSEFPKLLDAMGALMREPKDYSDAVAKLTMPVMLIYGDADMIR
HHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEEECCCHHCC
PEHIIDFYHKLGGGLRDAGWMRENMSKNRLAILPDLTHYETFASPLMANVAMTFLDGGGK
HHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
TPNWAEQVGK
CCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9578475 [H]