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The map label for this gene is rpoC [H]

Identifier: 209548928

GI number: 209548928

Start: 1352690

End: 1356898

Strand: Direct

Name: rpoC [H]

Synonym: Rleg2_1325

Alternate gene names: 209548928

Gene position: 1352690-1356898 (Clockwise)

Preceding gene: 209548927

Following gene: 209548930

Centisome position: 29.81

GC content: 60.85

Gene sequence:

>4209_bases
ATGAACCAAGAGGTCATGAATCTTTTCAATCCGCAGGTGCCTGCACAGAATTTCGATTCCATTCGGATTTCGATCGCATC
TCCGGAGAAGATCCTCTCCTGGTCTTACGGTGAGATCAAGAAGCCGGAAACCATCAACTACCGAACGTTCAAGCCGGAAC
GCGACGGTCTGTTCTGCGCGCGCATCTTCGGGCCGATCAAGGACTACGAATGCCTGTGCGGCAAGTACAAGCGCATGAAG
TACAAGGGCATCATCTGCGAAAAGTGCGGCGTCGAAGTCACGCTGTCACGCGTTCGCCGTGAGCGCATGGGCCATATCGA
GCTCGCCGCTCCCGTTGCCCATATCTGGTTCCTGAAGTCGCTGCCGTCGCGCATTTCGACGCTGCTCGACATGACGCTGA
AGGATGTCGAGCGCGTCCTCTATTTCGAAAACTACATCGTCACCGAGCCGGGCCTGACTGCTCTGAAGGAGCACCAGCTC
CTCTCGGAAGAAGAGTACATGCTGGCCGTTGACGAATACGGCGAAGACCAGTTCACCGCGATGATCGGCGCTGAGGCGAT
CTACGAGATGCTGGCCTCGATGAACCTCGAAAAGATCGCTGGCGACCTGCGCTCCGAGCTTGCCGACACCACGTCGGACC
TCAAGCAGAAGAAGCTGATGAAGCGCCTGAAGATCGTCGAGAACTTCATGGAGTCGGGCAACCGTCCGGAATGGATGATC
ATGAAGGTCGTTCCGGTGATCCCGCCGGATCTGCGTCCGCTGGTGCCGCTCGACGGCGGCCGTTTCGCGACGTCGGATCT
GAACGATCTCTACCGCCGCGTCATCAACCGCAACAACCGTCTGAAGCGTCTGATCGAGCTCCGTGCACCGGGCATCATCA
TCCGCAATGAAAAGCGCATGCTGCAGGAATCGGTTGACGCGCTGTTCGACAACGGCCGTCGCGGCCGCGTCATCACCGGC
GCCAACAAGCGTCCGCTGAAGTCGCTGTCCGACATGCTGAAGGGCAAGCAGGGCCGCTTCCGCCAGAACCTGCTCGGCAA
GCGCGTCGACTATTCCGGCCGTTCGGTCATCGTGACCGGTCCGGAACTGAAGCTGCACCAGTGCGGCCTGCCGAAGAAGA
TGGCGCTCGAGCTCTTCAAGCCGTTCATCTACGCCCGCCTCGACGCCAAGGGTTACTCCTCGACCGTCAAGCAGGCCAAG
AAGCTGGTCGAAAAGGAAAAGCCGGAAGTCTGGGATATCCTCGACGAGGTCATCCGCGAGCATCCGGTTCTGCTGAACCG
CGCACCGACGCTGCACCGCCTGGGCATCCAGGCCTTCGAACCCACCCTGGTCGAAGGCAAGGCGATCCAGCTGCATCCGC
TCGTCTGCACGGCCTTCAACGCCGACTTCGACGGCGACCAGATGGCCGTTCACGTGCCGCTGTCGCTCGAAGCCCAGCTC
GAAGCCCGCGTGCTGATGATGTCGACCAACAACATCCTGCATCCGGCCAACGGCGCGCCGATCATCGTTCCCTCGCAGGA
CATGGTTCTCGGCCTCTATTACCTGTCGATCCTCAACCAGAACGAACCGGGCGAAGGCATGGCTTTCTCCGATCTCGGCG
AACTGCATCACGCCCTCGAAAGCAAGGTCGTGACGCTGCACACCAAGATCCGCGGCCGTTTCAAGTCGGTCGACGAGGAT
GGCAAGCCCTACTCGAAGATCTATGAGACGACGCCTGGCCGTCTGCTCATCGGCGAACTGCTGCCGAAGAACGGCAAGGT
GCCCTTCGACATCTGCAACCAGGAAATGACCAAGAAGAACATCTCCAAGATGATCGACACGGTCTACCGCCATTGCGGCC
AGAAGGACACGGTCATCTTCTGCGACCGCATCATGCAGCTCGGCTTCTCCCATGCCTGCCGCGCCGGCATTTCGTTCGGC
AAGGACGACATGGTCATTCCGGATGCCAAGGCCAAGATCGTTGCCGACACCGAAACCCTGGTGAAGGAATACGAGCAGCA
GTACAATGACGGCCTGATCACTCAGGGCGAAAAGTACAACAAGGTTGTCGACGCCTGGGGCAAGGCCACCGAAAAGGTCG
CCGAAGAGATGATGGCCCGCATTAAGGCCGTCGAATTCGACGAGAACACCGGCCGTCAGAAGCCGATGAACTCGATCTAC
ATGATGAGCCATTCCGGCGCCCGCGGTTCTCCGAACCAGATGCGTCAGTTGGGCGGCATGCGCGGCCTCATGGCCAAGCC
GTCGGGTGAAATCATCGAGACGCCGATCATCTCGAACTTCAAGGAAGGCCTGACCGTCAACGAGTACTTCAACTCGACGC
ACGGCGCCCGAAAGGGTCTGGCAGACACTGCCTTGAAGACCGCCAACTCCGGTTACCTGACCCGCCGTCTCGTCGACGTC
GCGCAGGATTGCATCGTCACGCACGTCGATTGCGGCACCGAAACCGGCCTCACCATGACCGCCATCGTCGATGCCGGCCA
GGTGGTTGCCTCGATCGGCGTCCGCATCCTCGGCCGCACGGCACTTGATGACATCGATCATCCGATCACGGGTGAGCGCA
TCGTCGATGCCGGCCGGATGATCCTCGAGCCCGATGTCGTCGAAATCGAGAAGGCCGGTATCCAGTCGATCCGCATCCGC
TCGGCGCTGACCTGCGAAATCCAGACGGGCGTCTGCGCAGTCTGCTACGGCCGCGACCTGGCCCGTGGTACGCCTGTGAA
CATGGGCGAAGCCGTCGGCGTCATCGCTGCTCAGTCGATCGGTGAACCGGGCACCCAGCTCACCATGCGTACCTTCCACC
TTGGCGGTACGGCAACCGTGGTCGACCAGTCGTTCCTGGAAGCCTCGTACGAAGGTACGGTGCAGATCAAGAACCGCAAC
ATCCTGCGCAACTCCGATGGCAACCTCGTCGCCATGGGCCGCAACATGACCGTCCAGATCCTGGACGAGCGTGGCGTGGA
ACGGTCTTCGCAGCGTGTCGCCTACGGTTCGAAGCTGCATGTCGACGAAGGCGACAAGGTCAAGCGCGGCCAGCGTCTGG
CCGAGTGGGATCCTTACACCCGTCCGATGATGACCGAAGTTGCTGGTACCGTTCAGTTCGAAGACCTGGTCGACGGTCTC
TCGGTTCTGGAAGCGACCGACGAATCCACCGGCATCACCAAGCGCCAGGTCATCGACTGGCGTTCGACCCCGCGCGGTTC
GGACCTCAAGCCGGCGATCGTCATCAAGGATGCCAGCGGCAATGTCATGAAGCTGTCGCGTGGCGGTGACGCCCGCTTCA
TGCTCTCGGTCGACGCTATTCTGTCGGTTGAGCCGGGCACCAAGGTCTCCCAGGGTGACGTTCTCGCGCGTTCGCCGCTG
GAAAGCGCCAAGACCAAGGACATCACCGGCGGTCTGCCGCGTGTTGCCGAGCTCTTCGAAGCCCGCCGTCCGAAGGACCA
TGCCATCATCGCAGAGATCGATGGTACGATCCGCCTCGGCCGCGACTACAAGAACAAGCGCCGCGTCATCATCGAGCCGG
CGGAAGACGGTGTCGAGCCTGTCGAATACCTGATCCCGAAGGGCAAGCCCTTCCACCTTCAGGAAGGCGACTATATCGAA
AAGGGTGACTACATCCTCGACGGTAACCCGGCTCCGCACGACATCCTGGCGATCAAGGGCGTGGAGGCTCTGGCCTCCTA
CCTCGTCAACGAGATCCAGGAAGTCTACCGCCTGCAGGGTGTTGTCATCAACGACAAGCACATCGAGGTGATTGTCCGTC
AGATGCTGCAGAAGGTGGAGATCACCGATGCAGGCGACTCGACCTATATCGTCGGCGACAACGTCGACCGGATCGAGCTC
GAAGACGTCAACGATCACCTGATCGAGCAGGGCAAGAAGCCGGCCTACGGCGATCCGGTTCTTCTCGGCATCACCAAGGC
GTCGCTGCAGACCCCGTCCTTCATCTCGGCCGCATCCTTCCAGGAAACGACCAAGGTGCTGACGGAAGCTGCGATCGCCG
GCAAGACCGACGGTCTGCAGGGTCTGAAGGAAAACGTCATCGTCGGCCGTCTCATCCCGGCCGGTACCGGCGGCACCATG
ACCCAGATCCGCCGTATCGCCACGTCGCGCGACGAGCTGATCCTCGAAGAGCGCCGCAAGGGCACGGGTGCTGCGGTTGC
CACGCCGATGCTGCAGGACATGGCCGAAAAGGCTCCGGCTGCGGAATAA

Upstream 100 bases:

>100_bases
ATCTTGCGGTTATTCTCGTTTAAGCGAGGGAGGCGGCTCCCGGGAATTTGCCGCCGACCATCGCATTTTGAGGGCGCTTT
AGCCCATGAAGGAGACAGGC

Downstream 100 bases:

>100_bases
TCCGCAGCCGACGACCACCACTCAGGTGGCACGCGAATTGAAAAACCGCCCGGAGCGATCCGGGCGGTTTTTGTTTTTGG
TCTGCAGGTAGGTTGGGGGA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1402; Mature: 1402

Protein sequence:

>1402_residues
MNQEVMNLFNPQVPAQNFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRISTLLDMTLKDVERVLYFENYIVTEPGLTALKEHQL
LSEEEYMLAVDEYGEDQFTAMIGAEAIYEMLASMNLEKIAGDLRSELADTTSDLKQKKLMKRLKIVENFMESGNRPEWMI
MKVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQESVDALFDNGRRGRVITG
ANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAK
KLVEKEKPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPTLVEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSILNQNEPGEGMAFSDLGELHHALESKVVTLHTKIRGRFKSVDED
GKPYSKIYETTPGRLLIGELLPKNGKVPFDICNQEMTKKNISKMIDTVYRHCGQKDTVIFCDRIMQLGFSHACRAGISFG
KDDMVIPDAKAKIVADTETLVKEYEQQYNDGLITQGEKYNKVVDAWGKATEKVAEEMMARIKAVEFDENTGRQKPMNSIY
MMSHSGARGSPNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDV
AQDCIVTHVDCGTETGLTMTAIVDAGQVVASIGVRILGRTALDDIDHPITGERIVDAGRMILEPDVVEIEKAGIQSIRIR
SALTCEIQTGVCAVCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHLGGTATVVDQSFLEASYEGTVQIKNRN
ILRNSDGNLVAMGRNMTVQILDERGVERSSQRVAYGSKLHVDEGDKVKRGQRLAEWDPYTRPMMTEVAGTVQFEDLVDGL
SVLEATDESTGITKRQVIDWRSTPRGSDLKPAIVIKDASGNVMKLSRGGDARFMLSVDAILSVEPGTKVSQGDVLARSPL
ESAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGTIRLGRDYKNKRRVIIEPAEDGVEPVEYLIPKGKPFHLQEGDYIE
KGDYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVVINDKHIEVIVRQMLQKVEITDAGDSTYIVGDNVDRIEL
EDVNDHLIEQGKKPAYGDPVLLGITKASLQTPSFISAASFQETTKVLTEAAIAGKTDGLQGLKENVIVGRLIPAGTGGTM
TQIRRIATSRDELILEERRKGTGAAVATPMLQDMAEKAPAAE

Sequences:

>Translated_1402_residues
MNQEVMNLFNPQVPAQNFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRISTLLDMTLKDVERVLYFENYIVTEPGLTALKEHQL
LSEEEYMLAVDEYGEDQFTAMIGAEAIYEMLASMNLEKIAGDLRSELADTTSDLKQKKLMKRLKIVENFMESGNRPEWMI
MKVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQESVDALFDNGRRGRVITG
ANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAK
KLVEKEKPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPTLVEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSILNQNEPGEGMAFSDLGELHHALESKVVTLHTKIRGRFKSVDED
GKPYSKIYETTPGRLLIGELLPKNGKVPFDICNQEMTKKNISKMIDTVYRHCGQKDTVIFCDRIMQLGFSHACRAGISFG
KDDMVIPDAKAKIVADTETLVKEYEQQYNDGLITQGEKYNKVVDAWGKATEKVAEEMMARIKAVEFDENTGRQKPMNSIY
MMSHSGARGSPNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDV
AQDCIVTHVDCGTETGLTMTAIVDAGQVVASIGVRILGRTALDDIDHPITGERIVDAGRMILEPDVVEIEKAGIQSIRIR
SALTCEIQTGVCAVCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHLGGTATVVDQSFLEASYEGTVQIKNRN
ILRNSDGNLVAMGRNMTVQILDERGVERSSQRVAYGSKLHVDEGDKVKRGQRLAEWDPYTRPMMTEVAGTVQFEDLVDGL
SVLEATDESTGITKRQVIDWRSTPRGSDLKPAIVIKDASGNVMKLSRGGDARFMLSVDAILSVEPGTKVSQGDVLARSPL
ESAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGTIRLGRDYKNKRRVIIEPAEDGVEPVEYLIPKGKPFHLQEGDYIE
KGDYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVVINDKHIEVIVRQMLQKVEITDAGDSTYIVGDNVDRIEL
EDVNDHLIEQGKKPAYGDPVLLGITKASLQTPSFISAASFQETTKVLTEAAIAGKTDGLQGLKENVIVGRLIPAGTGGTM
TQIRRIATSRDELILEERRKGTGAAVATPMLQDMAEKAPAAE
>Mature_1402_residues
MNQEVMNLFNPQVPAQNFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRISTLLDMTLKDVERVLYFENYIVTEPGLTALKEHQL
LSEEEYMLAVDEYGEDQFTAMIGAEAIYEMLASMNLEKIAGDLRSELADTTSDLKQKKLMKRLKIVENFMESGNRPEWMI
MKVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQESVDALFDNGRRGRVITG
ANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAK
KLVEKEKPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPTLVEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSILNQNEPGEGMAFSDLGELHHALESKVVTLHTKIRGRFKSVDED
GKPYSKIYETTPGRLLIGELLPKNGKVPFDICNQEMTKKNISKMIDTVYRHCGQKDTVIFCDRIMQLGFSHACRAGISFG
KDDMVIPDAKAKIVADTETLVKEYEQQYNDGLITQGEKYNKVVDAWGKATEKVAEEMMARIKAVEFDENTGRQKPMNSIY
MMSHSGARGSPNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDV
AQDCIVTHVDCGTETGLTMTAIVDAGQVVASIGVRILGRTALDDIDHPITGERIVDAGRMILEPDVVEIEKAGIQSIRIR
SALTCEIQTGVCAVCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHLGGTATVVDQSFLEASYEGTVQIKNRN
ILRNSDGNLVAMGRNMTVQILDERGVERSSQRVAYGSKLHVDEGDKVKRGQRLAEWDPYTRPMMTEVAGTVQFEDLVDGL
SVLEATDESTGITKRQVIDWRSTPRGSDLKPAIVIKDASGNVMKLSRGGDARFMLSVDAILSVEPGTKVSQGDVLARSPL
ESAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGTIRLGRDYKNKRRVIIEPAEDGVEPVEYLIPKGKPFHLQEGDYIE
KGDYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVVINDKHIEVIVRQMLQKVEITDAGDSTYIVGDNVDRIEL
EDVNDHLIEQGKKPAYGDPVLLGITKASLQTPSFISAASFQETTKVLTEAAIAGKTDGLQGLKENVIVGRLIPAGTGGTM
TQIRRIATSRDELILEERRKGTGAAVATPMLQDMAEKAPAAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=917, Percent_Identity=25.4089422028353, Blast_Score=185, Evalue=3e-46,
Organism=Homo sapiens, GI39725938, Length=844, Percent_Identity=25.9478672985782, Blast_Score=175, Evalue=3e-43,
Organism=Homo sapiens, GI103471997, Length=250, Percent_Identity=30.4, Blast_Score=91, Evalue=7e-18,
Organism=Escherichia coli, GI2367335, Length=1410, Percent_Identity=58.5106382978723, Blast_Score=1656, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=923, Percent_Identity=24.4853737811484, Blast_Score=166, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI25145495, Length=310, Percent_Identity=31.6129032258064, Blast_Score=136, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6320061, Length=903, Percent_Identity=23.0343300110742, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6324690, Length=357, Percent_Identity=31.6526610644258, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281360912, Length=868, Percent_Identity=25.5760368663594, Blast_Score=163, Evalue=7e-40,
Organism=Drosophila melanogaster, GI17530899, Length=491, Percent_Identity=27.0875763747454, Blast_Score=149, Evalue=1e-35,
Organism=Drosophila melanogaster, GI17647875, Length=712, Percent_Identity=22.8932584269663, Blast_Score=120, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 155554; Mature: 155554

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQEVMNLFNPQVPAQNFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCA
CCHHHHHHCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHHCCCEEHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
LPSRISTLLDMTLKDVERVLYFENYIVTEPGLTALKEHQLLSEEEYMLAVDEYGEDQFTA
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHCCCCCEEEEEECCCCCHHHH
MIGAEAIYEMLASMNLEKIAGDLRSELADTTSDLKQKKLMKRLKIVENFMESGNRPEWMI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
MKVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRM
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQESVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKEKPEVWDILDEVIRE
CCEEEHHCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFEPTLVEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHCCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEECCEECCCC
EARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSILNQNEPGEGMAFSDLGELHHALE
CEEEEEEECCCEEECCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
SKVVTLHTKIRGRFKSVDEDGKPYSKIYETTPGRLLIGELLPKNGKVPFDICNQEMTKKN
CCEEEEEHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEHHHCCCCCCCCHHHHCHHHHHHH
ISKMIDTVYRHCGQKDTVIFCDRIMQLGFSHACRAGISFGKDDMVIPDAKAKIVADTETL
HHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCEECCCCCCEEEECHHHH
VKEYEQQYNDGLITQGEKYNKVVDAWGKATEKVAEEMMARIKAVEFDENTGRQKPMNSIY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEE
MMSHSGARGSPNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGL
EEECCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHCCCHHHHHCCCCHHHCCH
ADTALKTANSGYLTRRLVDVAQDCIVTHVDCGTETGLTMTAIVDAGQVVASIGVRILGRT
HHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
ALDDIDHPITGERIVDAGRMILEPDVVEIEKAGIQSIRIRSALTCEIQTGVCAVCYGRDL
HHHHCCCCCCCCHHHHCCCEEECCCHHHHHHHCCHHEEECEEEEEEECCCEEEEEECCHH
ARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHLGGTATVVDQSFLEASYEGTVQIKNRN
CCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCC
ILRNSDGNLVAMGRNMTVQILDERGVERSSQRVAYGSKLHVDEGDKVKRGQRLAEWDPYT
EEECCCCCEEEECCCCEEEEECCCCCCCCCCCEECCCEEECCCCCHHHHCCCCCCCCCCC
RPMMTEVAGTVQFEDLVDGLSVLEATDESTGITKRQVIDWRSTPRGSDLKPAIVIKDASG
CHHHHHHHCCEEHHHHHHHHHHHHCCCCCCCCCHHHEECCCCCCCCCCCCCEEEEECCCC
NVMKLSRGGDARFMLSVDAILSVEPGTKVSQGDVLARSPLESAKTKDITGGLPRVAELFE
CEEEEECCCCEEEEEEEEEEEEECCCCCCCCCCCEECCCHHHCCCCCCCCCCHHHHHHHH
ARRPKDHAIIAEIDGTIRLGRDYKNKRRVIIEPAEDGVEPVEYLIPKGKPFHLQEGDYIE
HCCCCCCEEEEEECCEEEECCCCCCCCEEEEECCCCCCCHHHHHCCCCCEEECCCCCEEE
KGDYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVVINDKHIEVIVRQMLQKVE
CCCEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHCC
ITDAGDSTYIVGDNVDRIELEDVNDHLIEQGKKPAYGDPVLLGITKASLQTPSFISAASF
CCCCCCCEEEECCCCCEEEECCCHHHHHHCCCCCCCCCCEEEEEEHHCCCCCCHHHHHHH
QETTKVLTEAAIAGKTDGLQGLKENVIVGRLIPAGTGGTMTQIRRIATSRDELILEERRK
HHHHHHHHHHHHCCCCCCHHHHHHCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHCC
GTGAAVATPMLQDMAEKAPAAE
CCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNQEVMNLFNPQVPAQNFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCA
CCHHHHHHCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHHCCCEEHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
LPSRISTLLDMTLKDVERVLYFENYIVTEPGLTALKEHQLLSEEEYMLAVDEYGEDQFTA
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHCCCCCEEEEEECCCCCHHHH
MIGAEAIYEMLASMNLEKIAGDLRSELADTTSDLKQKKLMKRLKIVENFMESGNRPEWMI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
MKVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRM
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQESVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKEKPEVWDILDEVIRE
CCEEEHHCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFEPTLVEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHCCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEECCEECCCC
EARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSILNQNEPGEGMAFSDLGELHHALE
CEEEEEEECCCEEECCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
SKVVTLHTKIRGRFKSVDEDGKPYSKIYETTPGRLLIGELLPKNGKVPFDICNQEMTKKN
CCEEEEEHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEHHHCCCCCCCCHHHHCHHHHHHH
ISKMIDTVYRHCGQKDTVIFCDRIMQLGFSHACRAGISFGKDDMVIPDAKAKIVADTETL
HHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCEECCCCCCEEEECHHHH
VKEYEQQYNDGLITQGEKYNKVVDAWGKATEKVAEEMMARIKAVEFDENTGRQKPMNSIY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEE
MMSHSGARGSPNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGL
EEECCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHCCCHHHHHCCCCHHHCCH
ADTALKTANSGYLTRRLVDVAQDCIVTHVDCGTETGLTMTAIVDAGQVVASIGVRILGRT
HHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
ALDDIDHPITGERIVDAGRMILEPDVVEIEKAGIQSIRIRSALTCEIQTGVCAVCYGRDL
HHHHCCCCCCCCHHHHCCCEEECCCHHHHHHHCCHHEEECEEEEEEECCCEEEEEECCHH
ARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHLGGTATVVDQSFLEASYEGTVQIKNRN
CCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCC
ILRNSDGNLVAMGRNMTVQILDERGVERSSQRVAYGSKLHVDEGDKVKRGQRLAEWDPYT
EEECCCCCEEEECCCCEEEEECCCCCCCCCCCEECCCEEECCCCCHHHHCCCCCCCCCCC
RPMMTEVAGTVQFEDLVDGLSVLEATDESTGITKRQVIDWRSTPRGSDLKPAIVIKDASG
CHHHHHHHCCEEHHHHHHHHHHHHCCCCCCCCCHHHEECCCCCCCCCCCCCEEEEECCCC
NVMKLSRGGDARFMLSVDAILSVEPGTKVSQGDVLARSPLESAKTKDITGGLPRVAELFE
CEEEEECCCCEEEEEEEEEEEEECCCCCCCCCCCEECCCHHHCCCCCCCCCCHHHHHHHH
ARRPKDHAIIAEIDGTIRLGRDYKNKRRVIIEPAEDGVEPVEYLIPKGKPFHLQEGDYIE
HCCCCCCEEEEEECCEEEECCCCCCCCEEEEECCCCCCCHHHHHCCCCCEEECCCCCEEE
KGDYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVVINDKHIEVIVRQMLQKVE
CCCEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHCC
ITDAGDSTYIVGDNVDRIELEDVNDHLIEQGKKPAYGDPVLLGITKASLQTPSFISAASF
CCCCCCCEEEECCCCCEEEECCCHHHHHHCCCCCCCCCCEEEEEEHHCCCCCCHHHHHHH
QETTKVLTEAAIAGKTDGLQGLKENVIVGRLIPAGTGGTMTQIRRIATSRDELILEERRK
HHHHHHHHHHHHCCCCCCHHHHHHCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHCC
GTGAAVATPMLQDMAEKAPAAE
CCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]