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The map label for this gene is nuoC1 [H]

Identifier: 209548864

GI number: 209548864

Start: 1277806

End: 1278408

Strand: Direct

Name: nuoC1 [H]

Synonym: Rleg2_1261

Alternate gene names: 209548864

Gene position: 1277806-1278408 (Clockwise)

Preceding gene: 209548863

Following gene: 209548865

Centisome position: 28.16

GC content: 60.36

Gene sequence:

>603_bases
ATGAGTGAAGCCCTGACTGAGCTTGCGTCCTACCTTGGCGAAGCGCGCGGCAATCTGATCGCCGCATCGCAGATGAAGTA
TGGCGAGCTGACGCTGACGACGACGGGTGAAAACCTGATCGCGCTTTTGACCTTCCTGCGTGACGACGCCAAATGCGGTT
TCGTCAACCTGATCGATATTTGCGGCGTCGACTGGCCGCAGCGCGAGCTGCGTTTCGACGTCGTCTATCACCTGCTGTCG
CCGAAGCAGAATGTGCGCATCCGCGTCAAGGTCGCGACCGACGAAGATACGCCGGTTCCCTCGGCCTGTGCCGTCCATCC
CGGTGCCGACTGGTTCGAGCGCGAAACCTGGGACATGTACGGCGTGCTCTTCACCGGCCATCCGGACCTGCGCCGCATCC
TGACCGACTACGGCTTCGAAGGCCATCCGCTGCGCAAGGACTTCCCGACCACCGGTTTCGTCGAGGTCCGCTACGACGAC
GCCGCCAAGCGAGTCGTCTATGAGCCGGTTGAGCTCAAACAGGAATTCCGCAATTTCGATTTTATGTCGCCCTGGGAAGG
CACGGACTACGTGCTGCCCGGCGATGAAAAAGCGAAGCAATAA

Upstream 100 bases:

>100_bases
TCCCCCCACGGCAGAGGCGCTGCTTTACGGCGTGCTTCTGCTGCAGAAGAAGATCCGGCGCACCGGCACGATCGAACGCT
AAGGGTTAAGGACAAGGCAT

Downstream 100 bases:

>100_bases
ATTCAAGGCGGCTGGTGGGTTTGTGCCTGCCATTCACTGGTTATCTGAGAACGCGAGCGCATCGCCATGACAGAACATAA
CGTCCGCAACTTCAACATCA

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C 1; NDH-1 subunit C 1 [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSEALTELASYLGEARGNLIAASQMKYGELTLTTTGENLIALLTFLRDDAKCGFVNLIDICGVDWPQRELRFDVVYHLLS
PKQNVRIRVKVATDEDTPVPSACAVHPGADWFERETWDMYGVLFTGHPDLRRILTDYGFEGHPLRKDFPTTGFVEVRYDD
AAKRVVYEPVELKQEFRNFDFMSPWEGTDYVLPGDEKAKQ

Sequences:

>Translated_200_residues
MSEALTELASYLGEARGNLIAASQMKYGELTLTTTGENLIALLTFLRDDAKCGFVNLIDICGVDWPQRELRFDVVYHLLS
PKQNVRIRVKVATDEDTPVPSACAVHPGADWFERETWDMYGVLFTGHPDLRRILTDYGFEGHPLRKDFPTTGFVEVRYDD
AAKRVVYEPVELKQEFRNFDFMSPWEGTDYVLPGDEKAKQ
>Mature_199_residues
SEALTELASYLGEARGNLIAASQMKYGELTLTTTGENLIALLTFLRDDAKCGFVNLIDICGVDWPQRELRFDVVYHLLSP
KQNVRIRVKVATDEDTPVPSACAVHPGADWFERETWDMYGVLFTGHPDLRRILTDYGFEGHPLRKDFPTTGFVEVRYDDA
AKRVVYEPVELKQEFRNFDFMSPWEGTDYVLPGDEKAKQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=186, Percent_Identity=53.763440860215, Blast_Score=209, Evalue=1e-54,
Organism=Escherichia coli, GI145693162, Length=163, Percent_Identity=37.4233128834356, Blast_Score=98, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71990788, Length=185, Percent_Identity=51.3513513513513, Blast_Score=195, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI32563621, Length=185, Percent_Identity=51.3513513513513, Blast_Score=194, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24656494, Length=183, Percent_Identity=56.2841530054645, Blast_Score=218, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 22816; Mature: 22685

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEALTELASYLGEARGNLIAASQMKYGELTLTTTGENLIALLTFLRDDAKCGFVNLIDI
CCHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEHHHH
CGVDWPQRELRFDVVYHLLSPKQNVRIRVKVATDEDTPVPSACAVHPGADWFERETWDMY
HCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEECCCCHHHHCCCCEEE
GVLFTGHPDLRRILTDYGFEGHPLRKDFPTTGFVEVRYDDAAKRVVYEPVELKQEFRNFD
EEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCHHHHHEECCHHHHHHHHCCC
FMSPWEGTDYVLPGDEKAKQ
CCCCCCCCCEEECCCHHCCC
>Mature Secondary Structure 
SEALTELASYLGEARGNLIAASQMKYGELTLTTTGENLIALLTFLRDDAKCGFVNLIDI
CHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEHHHH
CGVDWPQRELRFDVVYHLLSPKQNVRIRVKVATDEDTPVPSACAVHPGADWFERETWDMY
HCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEECCCCHHHHCCCCEEE
GVLFTGHPDLRRILTDYGFEGHPLRKDFPTTGFVEVRYDDAAKRVVYEPVELKQEFRNFD
EEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCHHHHHEECCHHHHHHHHCCC
FMSPWEGTDYVLPGDEKAKQ
CCCCCCCCCEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA