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The map label for this gene is iolS [H]

Identifier: 209548856

GI number: 209548856

Start: 1271591

End: 1272577

Strand: Reverse

Name: iolS [H]

Synonym: Rleg2_1253

Alternate gene names: 209548856

Gene position: 1272577-1271591 (Counterclockwise)

Preceding gene: 209548858

Following gene: 209548849

Centisome position: 28.04

GC content: 64.64

Gene sequence:

>987_bases
ATGAAACACCATGCTTTCGGCCGCATGCCCTTCACCATCACCAATGTCGGCTTCGGCGCCTGGCAGATCGGCGGCTCCTG
GGGCGATATCAGCGAAGCGGATGGCCGTGCGGCGCTGAATGCCGCGCTCGATGCCGGCATGACCTTCATCGACACGGCTG
ACGTCTATGGCGACGGCCGCTCGGAAAAGATCATCGCCGACGTGCTGAAGACGCGCGGCGGCGAGCGGCCGATGGTCGCC
ACCAAGGCGGGCCGCCGGCTCAATCCGCATGTCGCCGAAGGATATACCAAGGCCAATCTCGAAGGCTTCATCGACCGCAG
CCTCAAGAATCTTGCCGTCGACAGCCTCGACCTCGTGCAGCTTCACTGCCCGCCGCGCGAGGTGTTTTACCAGCCCGAGG
TCTTCGAAAGTCTCGATGCGCTGCAGAAGGCCGGCAAGATCAAGGGGTACGGCGTCAGCGTCGAAAAGGTCGAGGACGGG
CTGAAGGCGATCGAATATCCCGGCGTCGTCAGCATCCAGATCATCTACAACATCTTCCGCCAGCGCCCCGACCACCTGTT
CTTCGAGGAGGCGCGCCGTAAAAACGTGGCGATCATCGCCCGCGTGCCGCTGGCCAGCGGTCTGCTCTCCGGCAAGATCA
CCCGGGAAACGCACTTTGCCAGCGACGACCACCGCAATTTCAACCGTCACGGTGAAGCCTTCGATGTCGGCGAGACCTTT
GCCGGCGTACCCTTCGAGGTCGGCCTGCAGGCGGTCGAGGAGGTGCGCAAGCTGGTGCCCGCAGGCGCCACCATGGCGGC
CTTCGCGCTGCGCTGGATCCTGATGGCAGAAGCCGTCACCGTCGTCATCCCCGGCGCCCGCAATGGCGAACAGGCAAGAG
CCAATGCGGCCGCCGCCGACCTGGCACCGCTTGCGGCCGATGTCATGGCGGCAACGCGCGAGATCTACGAGCGGCTGATC
GCGCCGCATGTGCATCAGCGCTGGTAG

Upstream 100 bases:

>100_bases
ACTTGGTTGATGCGACGCGCTTTAGTTCTCTGTTTTTACGCATGTCGTTATTCCGGAATCGCTGCACACTTCCGGGCAAC
ATGCATTGGGAGAATTTCTC

Downstream 100 bases:

>100_bases
GGTTGGGGCTGCTTGTTTTTGAGGGCTGCGGGAAGCGTCGATGACTCGCCGTTGTTGAAGGTCTCACAACTTTCGTCCGT
CATATTCCAGGCCTTGCGCC

Product: aldo/keto reductase

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKHHAFGRMPFTITNVGFGAWQIGGSWGDISEADGRAALNAALDAGMTFIDTADVYGDGRSEKIIADVLKTRGGERPMVA
TKAGRRLNPHVAEGYTKANLEGFIDRSLKNLAVDSLDLVQLHCPPREVFYQPEVFESLDALQKAGKIKGYGVSVEKVEDG
LKAIEYPGVVSIQIIYNIFRQRPDHLFFEEARRKNVAIIARVPLASGLLSGKITRETHFASDDHRNFNRHGEAFDVGETF
AGVPFEVGLQAVEEVRKLVPAGATMAAFALRWILMAEAVTVVIPGARNGEQARANAAAADLAPLAADVMAATREIYERLI
APHVHQRW

Sequences:

>Translated_328_residues
MKHHAFGRMPFTITNVGFGAWQIGGSWGDISEADGRAALNAALDAGMTFIDTADVYGDGRSEKIIADVLKTRGGERPMVA
TKAGRRLNPHVAEGYTKANLEGFIDRSLKNLAVDSLDLVQLHCPPREVFYQPEVFESLDALQKAGKIKGYGVSVEKVEDG
LKAIEYPGVVSIQIIYNIFRQRPDHLFFEEARRKNVAIIARVPLASGLLSGKITRETHFASDDHRNFNRHGEAFDVGETF
AGVPFEVGLQAVEEVRKLVPAGATMAAFALRWILMAEAVTVVIPGARNGEQARANAAAADLAPLAADVMAATREIYERLI
APHVHQRW
>Mature_328_residues
MKHHAFGRMPFTITNVGFGAWQIGGSWGDISEADGRAALNAALDAGMTFIDTADVYGDGRSEKIIADVLKTRGGERPMVA
TKAGRRLNPHVAEGYTKANLEGFIDRSLKNLAVDSLDLVQLHCPPREVFYQPEVFESLDALQKAGKIKGYGVSVEKVEDG
LKAIEYPGVVSIQIIYNIFRQRPDHLFFEEARRKNVAIIARVPLASGLLSGKITRETHFASDDHRNFNRHGEAFDVGETF
AGVPFEVGLQAVEEVRKLVPAGATMAAFALRWILMAEAVTVVIPGARNGEQARANAAAADLAPLAADVMAATREIYERLI
APHVHQRW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436971, Length=314, Percent_Identity=23.5668789808917, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI223718702, Length=303, Percent_Identity=27.0627062706271, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081735, Length=321, Percent_Identity=27.4143302180685, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788070, Length=344, Percent_Identity=26.1627906976744, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789375, Length=318, Percent_Identity=25.7861635220126, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789199, Length=359, Percent_Identity=24.2339832869081, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788081, Length=221, Percent_Identity=28.0542986425339, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646159, Length=185, Percent_Identity=28.6486486486486, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646155, Length=281, Percent_Identity=24.9110320284698, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35857; Mature: 35857

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHHAFGRMPFTITNVGFGAWQIGGSWGDISEADGRAALNAALDAGMTFIDTADVYGDGR
CCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEECHHHCCCCC
SEKIIADVLKTRGGERPMVATKAGRRLNPHVAEGYTKANLEGFIDRSLKNLAVDSLDLVQ
CHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEE
LHCPPREVFYQPEVFESLDALQKAGKIKGYGVSVEKVEDGLKAIEYPGVVSIQIIYNIFR
EECCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
QRPDHLFFEEARRKNVAIIARVPLASGLLSGKITRETHFASDDHRNFNRHGEAFDVGETF
CCCCHHHHHHHCCCCEEEEEECCHHHHHHCCCCCHHHCCCCCCCCCCCCCCCEEECCCHH
AGVPFEVGLQAVEEVRKLVPAGATMAAFALRWILMAEAVTVVIPGARNGEQARANAAAAD
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHH
LAPLAADVMAATREIYERLIAPHVHQRW
HHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MKHHAFGRMPFTITNVGFGAWQIGGSWGDISEADGRAALNAALDAGMTFIDTADVYGDGR
CCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEECHHHCCCCC
SEKIIADVLKTRGGERPMVATKAGRRLNPHVAEGYTKANLEGFIDRSLKNLAVDSLDLVQ
CHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEE
LHCPPREVFYQPEVFESLDALQKAGKIKGYGVSVEKVEDGLKAIEYPGVVSIQIIYNIFR
EECCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
QRPDHLFFEEARRKNVAIIARVPLASGLLSGKITRETHFASDDHRNFNRHGEAFDVGETF
CCCCHHHHHHHCCCCEEEEEECCHHHHHHCCCCCHHHCCCCCCCCCCCCCCCEEECCCHH
AGVPFEVGLQAVEEVRKLVPAGATMAAFALRWILMAEAVTVVIPGARNGEQARANAAAAD
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHH
LAPLAADVMAATREIYERLIAPHVHQRW
HHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]