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The map label for this gene is speB [H]

Identifier: 209548834

GI number: 209548834

Start: 1244172

End: 1245134

Strand: Reverse

Name: speB [H]

Synonym: Rleg2_1231

Alternate gene names: 209548834

Gene position: 1245134-1244172 (Counterclockwise)

Preceding gene: 209548835

Following gene: 209548833

Centisome position: 27.44

GC content: 64.38

Gene sequence:

>963_bases
TTGGCGAACAAGTCCATTGATCATGCCTTCACGGCGACCAGCCTCACTTCCGCCGCCAGCGACCCGACCTTTGCCGGCGC
GCTGTCGTTCATGCGCCGCCGCTTCACCAAGGAGCTCGCCGGCGTCGACGTGGCCGTCTGGGGCATTCCCTTCGATGCGG
CAACCTCGAACAGGCCAGGTACGCGCTTCGGGCCGCAGGCGATCCGCCGCGCCTCGGCGATCTTCGACAATGATGCGCAA
TATCCCTTCAACCGCGATCTGTTCGCCGAGATGGCCGTGATCGACTACGGCGACTGCCTGCTCGATTACGGCAATCATCA
GGATACGCCTGCCGCCATCGAACGTCAGGCGAATGTCATTCTCGACAGCGGCGCCTTCCTGCTGACGCTCGGCGGCGATC
ACTATGTCACCTGGCCGCTGCTGAAAGCGCATGCGGCAAAACATGGGCCGCTCGCCCTTGTGCAGTTCGACGCGCACCAG
GACACCTGGTTCGACGAAGACCGGCGCATCGACCACGGTTCCTTCGTGGCACGCGCCGCCCGCGAGGGCATCATCGATCC
CGACCGCTCGATCCAGATCGGCATCCGCACCCATGCGCCGGAGGATTTCGGCGTCAATATTCTCTACGGCCATCAGGTCG
AGGAAATGAGCGCCGGCGATATCGCCTCGGCGATCATCTCGCATACGCGCGGCGCGCCTGCCTATCTCACCTTCGATATC
GATTGCCTCGACCCGGCCTTTGCGCCGGGCACCGGCACACCGGTCGCCGGCGGACCATCGAGCGCCAAGATCCTCTCGGT
GCTGCAGCGCCTGCACCAGCTCGATATCCGCGGCGCCGATATCGTCGAGGTATCGCCGCCCTACGACCATGCCGATATCA
CCGCCATTGCGGGGGCAACGGTGGCGATGTATATGCTGGGGCTTCATGCCGAGCGACGCGCCATCGCCGTGTCACAAGGC
TGA

Upstream 100 bases:

>100_bases
ATTTCGTCGCCCGGCGGTTTGGTCGTGACCGGTGACCGGCCGATATAAGGTCGACATCGAAAGCGGCTATGGTTCAGCGC
CCATAGAGAAGGAGCCCCTC

Downstream 100 bases:

>100_bases
CCTATTATCCCAAAATGAATCCGGAAACCTTCTGAACCCATTGAAAGCGCAGGTTAACATGGCACCGAAAATCTTCATCG
ACGGCGAACACGGCACGACG

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MANKSIDHAFTATSLTSAASDPTFAGALSFMRRRFTKELAGVDVAVWGIPFDAATSNRPGTRFGPQAIRRASAIFDNDAQ
YPFNRDLFAEMAVIDYGDCLLDYGNHQDTPAAIERQANVILDSGAFLLTLGGDHYVTWPLLKAHAAKHGPLALVQFDAHQ
DTWFDEDRRIDHGSFVARAAREGIIDPDRSIQIGIRTHAPEDFGVNILYGHQVEEMSAGDIASAIISHTRGAPAYLTFDI
DCLDPAFAPGTGTPVAGGPSSAKILSVLQRLHQLDIRGADIVEVSPPYDHADITAIAGATVAMYMLGLHAERRAIAVSQG

Sequences:

>Translated_320_residues
MANKSIDHAFTATSLTSAASDPTFAGALSFMRRRFTKELAGVDVAVWGIPFDAATSNRPGTRFGPQAIRRASAIFDNDAQ
YPFNRDLFAEMAVIDYGDCLLDYGNHQDTPAAIERQANVILDSGAFLLTLGGDHYVTWPLLKAHAAKHGPLALVQFDAHQ
DTWFDEDRRIDHGSFVARAAREGIIDPDRSIQIGIRTHAPEDFGVNILYGHQVEEMSAGDIASAIISHTRGAPAYLTFDI
DCLDPAFAPGTGTPVAGGPSSAKILSVLQRLHQLDIRGADIVEVSPPYDHADITAIAGATVAMYMLGLHAERRAIAVSQG
>Mature_319_residues
ANKSIDHAFTATSLTSAASDPTFAGALSFMRRRFTKELAGVDVAVWGIPFDAATSNRPGTRFGPQAIRRASAIFDNDAQY
PFNRDLFAEMAVIDYGDCLLDYGNHQDTPAAIERQANVILDSGAFLLTLGGDHYVTWPLLKAHAAKHGPLALVQFDAHQD
TWFDEDRRIDHGSFVARAAREGIIDPDRSIQIGIRTHAPEDFGVNILYGHQVEEMSAGDIASAIISHTRGAPAYLTFDID
CLDPAFAPGTGTPVAGGPSSAKILSVLQRLHQLDIRGADIVEVSPPYDHADITAIAGATVAMYMLGLHAERRAIAVSQG

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=291, Percent_Identity=37.8006872852234, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI10947139, Length=285, Percent_Identity=27.3684210526316, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4502215, Length=305, Percent_Identity=29.1803278688525, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789306, Length=305, Percent_Identity=40.9836065573771, Blast_Score=221, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 34453; Mature: 34322

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKSIDHAFTATSLTSAASDPTFAGALSFMRRRFTKELAGVDVAVWGIPFDAATSNRPG
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCC
TRFGPQAIRRASAIFDNDAQYPFNRDLFAEMAVIDYGDCLLDYGNHQDTPAAIERQANVI
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHEECCCCCCCHHHHHHCCCEE
LDSGAFLLTLGGDHYVTWPLLKAHAAKHGPLALVQFDAHQDTWFDEDRRIDHGSFVARAA
EECCCEEEEECCCCEEEHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
REGIIDPDRSIQIGIRTHAPEDFGVNILYGHQVEEMSAGDIASAIISHTRGAPAYLTFDI
HCCCCCCCCCEEEEEEECCCCCCCCEEEECCCHHHCCHHHHHHHHHHHCCCCCEEEEEEE
DCLDPAFAPGTGTPVAGGPSSAKILSVLQRLHQLDIRGADIVEVSPPYDHADITAIAGAT
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHH
VAMYMLGLHAERRAIAVSQG
HHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure 
ANKSIDHAFTATSLTSAASDPTFAGALSFMRRRFTKELAGVDVAVWGIPFDAATSNRPG
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCC
TRFGPQAIRRASAIFDNDAQYPFNRDLFAEMAVIDYGDCLLDYGNHQDTPAAIERQANVI
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHEECCCCCCCHHHHHHCCCEE
LDSGAFLLTLGGDHYVTWPLLKAHAAKHGPLALVQFDAHQDTWFDEDRRIDHGSFVARAA
EECCCEEEEECCCCEEEHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
REGIIDPDRSIQIGIRTHAPEDFGVNILYGHQVEEMSAGDIASAIISHTRGAPAYLTFDI
HCCCCCCCCCEEEEEEECCCCCCCCEEEECCCHHHCCHHHHHHHHHHHCCCCCEEEEEEE
DCLDPAFAPGTGTPVAGGPSSAKILSVLQRLHQLDIRGADIVEVSPPYDHADITAIAGAT
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHH
VAMYMLGLHAERRAIAVSQG
HHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]