Click here to switch to the map view.

The map label for this gene is guaA [H]

Identifier: 209548790

GI number: 209548790

Start: 1198922

End: 1199437

Strand: Reverse

Name: guaA [H]

Synonym: Rleg2_1187

Alternate gene names: 209548790

Gene position: 1199437-1198922 (Counterclockwise)

Preceding gene: 209548791

Following gene: 209548789

Centisome position: 26.43

GC content: 62.79

Gene sequence:

>516_bases
ATGACCGATATTCCAACCCTCGAAACCGAGCGGCTGACGCTCCGCCCGCACCGCCTCGACGATTTCGAGGCGCATGCGGC
ACTCTGGGCAGACGAAGATGTCGTCCGCTTCATCAGCGGCATCCCATCGACGCGCGAGCAGAGCTGGAGCCGCATGCTGC
GGATTGCCGGCATGTGGCACCATATGGGCTTCGGCTTTCTGGCAATCGAGGAAAAGGCGAGCGGCCGGTTCATCGGCGAA
GCGGGCTTCATGGAATCCCGCCGCGAGATGGAACCGTCGACCGAGGGAACGATGGAACTCGGCTGGGCGCTGATGCCCTC
GGTACACGGCGGCGGTTATGCCACCGAGGCGCTGACCGCGCTGATCGGTTGGGCGGAGCGCTATTTCCCCGGAAAACCGA
TGAGCTGCATCATCAGCCCGGAGAACCAGGCCTCGTTGAGGGTCGCAGCCAAACTCGGTTTTAGCGAGACCACGCGCACC
CAGTACAACGGCGAGATCATTCAGTTTTCGCGGTAG

Upstream 100 bases:

>100_bases
AACGAGGAAGGTTCCGAACCTCTGCGCTTCCGCCATATCTGCCGGCCGGAAAGCGATCTCGACTATTGGGACGGCGAACC
CGGCGCTTGAAGGACCCGAA

Downstream 100 bases:

>100_bases
GCAAGCGCAAGCAAGGGGATAGCGACGACCTCGGCTTGCGGCACCCGACCTCCTCCTCGGATGGGTGCGGGCGTCGCACC
TGCTACGCGCAAGGAACGCG

Product: GCN5-like N-acetyltransferase

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MTDIPTLETERLTLRPHRLDDFEAHAALWADEDVVRFISGIPSTREQSWSRMLRIAGMWHHMGFGFLAIEEKASGRFIGE
AGFMESRREMEPSTEGTMELGWALMPSVHGGGYATEALTALIGWAERYFPGKPMSCIISPENQASLRVAAKLGFSETTRT
QYNGEIIQFSR

Sequences:

>Translated_171_residues
MTDIPTLETERLTLRPHRLDDFEAHAALWADEDVVRFISGIPSTREQSWSRMLRIAGMWHHMGFGFLAIEEKASGRFIGE
AGFMESRREMEPSTEGTMELGWALMPSVHGGGYATEALTALIGWAERYFPGKPMSCIISPENQASLRVAAKLGFSETTRT
QYNGEIIQFSR
>Mature_170_residues
TDIPTLETERLTLRPHRLDDFEAHAALWADEDVVRFISGIPSTREQSWSRMLRIAGMWHHMGFGFLAIEEKASGRFIGEA
GFMESRREMEPSTEGTMELGWALMPSVHGGGYATEALTALIGWAERYFPGKPMSCIISPENQASLRVAAKLGFSETTRTQ
YNGEIIQFSR

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 19229; Mature: 19098

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIPTLETERLTLRPHRLDDFEAHAALWADEDVVRFISGIPSTREQSWSRMLRIAGMWH
CCCCCCCCCCEEEECCCCCCCCHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
HMGFGFLAIEEKASGRFIGEAGFMESRREMEPSTEGTMELGWALMPSVHGGGYATEALTA
HCCCEEEEEECCCCCCEECCCCCHHHHHHCCCCCCCCHHCCCEECCCCCCCCHHHHHHHH
LIGWAERYFPGKPMSCIISPENQASLRVAAKLGFSETTRTQYNGEIIQFSR
HHHHHHHHCCCCCCEEEECCCCCCCEEEEEECCCCCCCCEECCCEEEEECC
>Mature Secondary Structure 
TDIPTLETERLTLRPHRLDDFEAHAALWADEDVVRFISGIPSTREQSWSRMLRIAGMWH
CCCCCCCCCEEEECCCCCCCCHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
HMGFGFLAIEEKASGRFIGEAGFMESRREMEPSTEGTMELGWALMPSVHGGGYATEALTA
HCCCEEEEEECCCCCCEECCCCCHHHHHHCCCCCCCCHHCCCEECCCCCCCCHHHHHHHH
LIGWAERYFPGKPMSCIISPENQASLRVAAKLGFSETTRTQYNGEIIQFSR
HHHHHHHHCCCCCCEEEECCCCCCCEEEEEECCCCCCCCEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]