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The map label for this gene is pgsA [H]

Identifier: 209548688

GI number: 209548688

Start: 1103481

End: 1104071

Strand: Reverse

Name: pgsA [H]

Synonym: Rleg2_1085

Alternate gene names: 209548688

Gene position: 1104071-1103481 (Counterclockwise)

Preceding gene: 209548689

Following gene: 209548687

Centisome position: 24.33

GC content: 60.58

Gene sequence:

>591_bases
ATGGCATCGCGTGCGTACAGCATCCCCAACCTCCTGACCTACGGCCGTATCCTCGCGGTACCGCTGATCGTTCTCTGCTT
CTTCATCGAGGGCAGGCTGTCGATCAGCAACACGGCGCGCTGGGTGGCACTGTGGATCTTCGTCATCGCCTCGATCACCG
ATTTCCTCGACGGCTATCTCGCGCGCATCTGGAATCAGACCTCGAATATCGGCCGCATGCTCGATCCGATTGCCGACAAG
CTGCTGGTCGCCTCGATCCTGCTGCTGGTCGCCGCCGACCAGACGATTGCCGGCTGGTCGATCTGGGCGGCGATCACCAT
TCTCTGCCGCGAGATCCTGGTGTCCGGCTTGCGCGAATATCTGGCGGCGCTGAAAGTCAGCGTGCCGGTGACGCGGATCG
CCAAGTGGAAGACGACGCTGCAACTCGTCGCCATCGCCTTCCTGCTCGCGGGACCTGCCGGCGACGAGATTTTCCCCTAT
ACGACGCAGACCGGCATCGCGCTGCTGTGGATTGCCGCACTGCTGACTATCTATACAGGCTATGATTATTTCCGTGCCGG
GCTGAAACATATCGTGGATGACGAGGAATGA

Upstream 100 bases:

>100_bases
CTCGATATCAGAAAAGCCCGATGCGTCGATTCAAAGTGTTACAGCGTCCTGAAAAGACGCGCGGCGCTGCAGCGGCGCAT
CAAGTCAGAGAAACGATCCC

Downstream 100 bases:

>100_bases
CGCGGCTTGTCTATTTCGCATGGGTGCGCGAGCGCATCGGCAAAGGCGAGGAGGAGATCGACCTCCCCTCCTCCGTCGTT
ACCGTGACCGATCTTCTGAA

Product: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MASRAYSIPNLLTYGRILAVPLIVLCFFIEGRLSISNTARWVALWIFVIASITDFLDGYLARIWNQTSNIGRMLDPIADK
LLVASILLLVAADQTIAGWSIWAAITILCREILVSGLREYLAALKVSVPVTRIAKWKTTLQLVAIAFLLAGPAGDEIFPY
TTQTGIALLWIAALLTIYTGYDYFRAGLKHIVDDEE

Sequences:

>Translated_196_residues
MASRAYSIPNLLTYGRILAVPLIVLCFFIEGRLSISNTARWVALWIFVIASITDFLDGYLARIWNQTSNIGRMLDPIADK
LLVASILLLVAADQTIAGWSIWAAITILCREILVSGLREYLAALKVSVPVTRIAKWKTTLQLVAIAFLLAGPAGDEIFPY
TTQTGIALLWIAALLTIYTGYDYFRAGLKHIVDDEE
>Mature_195_residues
ASRAYSIPNLLTYGRILAVPLIVLCFFIEGRLSISNTARWVALWIFVIASITDFLDGYLARIWNQTSNIGRMLDPIADKL
LVASILLLVAADQTIAGWSIWAAITILCREILVSGLREYLAALKVSVPVTRIAKWKTTLQLVAIAFLLAGPAGDEIFPYT
TQTGIALLWIAALLTIYTGYDYFRAGLKHIVDDEE

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI188536108, Length=204, Percent_Identity=28.4313725490196, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI10092647, Length=205, Percent_Identity=28.2926829268293, Blast_Score=64, Evalue=6e-11,
Organism=Escherichia coli, GI1788220, Length=191, Percent_Identity=39.2670157068063, Blast_Score=120, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6320059, Length=165, Percent_Identity=31.5151515151515, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21706; Mature: 21575

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRAYSIPNLLTYGRILAVPLIVLCFFIEGRLSISNTARWVALWIFVIASITDFLDGYL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARIWNQTSNIGRMLDPIADKLLVASILLLVAADQTIAGWSIWAAITILCREILVSGLREY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAALKVSVPVTRIAKWKTTLQLVAIAFLLAGPAGDEIFPYTTQTGIALLWIAALLTIYTG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
YDYFRAGLKHIVDDEE
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASRAYSIPNLLTYGRILAVPLIVLCFFIEGRLSISNTARWVALWIFVIASITDFLDGYL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARIWNQTSNIGRMLDPIADKLLVASILLLVAADQTIAGWSIWAAITILCREILVSGLREY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAALKVSVPVTRIAKWKTTLQLVAIAFLLAGPAGDEIFPYTTQTGIALLWIAALLTIYTG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
YDYFRAGLKHIVDDEE
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA