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The map label for this gene is moaE [H]

Identifier: 209548686

GI number: 209548686

Start: 1102575

End: 1103036

Strand: Reverse

Name: moaE [H]

Synonym: Rleg2_1083

Alternate gene names: 209548686

Gene position: 1103036-1102575 (Counterclockwise)

Preceding gene: 209548687

Following gene: 209548684

Centisome position: 24.31

GC content: 64.94

Gene sequence:

>462_bases
TTGACCCTCCCCCCCACCATCCGCGTTCAACGCGAAGACTTCGACCTTCAAGCCGAAGTCGACCGCCTTTCTAAAAACAA
CCCCGGCGTCGGCGCCATTGTCACCTTCTCCGGCCTCTGCCGCGATGACGGCGGAACCCTCGCCGCCCTTGAACTCGAAC
ATTACCCCGGCATGGCCGAAGCCGCGATGACCCGCATCGGCGAACTCGCCATCGAGCGCTTCGGGCTGCTCGGCCTCACC
GCCATCCACCGCTACGGCAAGATCGCCGTGGGCGAGAATATCGTCCTCGTCGTCGCGGTCGCGCCGCATCGGCAGGCGGC
ATTCGACGGCGCCAATTTTGTCATGGACTTCCTGAAGACCGCAGCCCCCTTCTGGAAGAAGGAGCACAGTCGGGATGGCG
CCGAGGGCGACTGGGTCGCGGCGAAAGACGCCGACGACGCGGCGCGCGACAAGTGGAAATAG

Upstream 100 bases:

>100_bases
CCCTTCGCTTGCGCTCAGTGCGTTCGCGGCTTTTGCCGCTCACCCCCCTCATCTGTCCTTCGGACATCTTCTCCCCGCTG
GGGAGAAGGGGGAGGTTGCA

Downstream 100 bases:

>100_bases
GCTAAAGCACCACCCGCTCCCTGCGGCTCATGACCAAGAGCAGAACGAGCAGCGAAAAGATGACGAAATCGCGCCAGACG
AAGGGGCCATAGGCGCCCCA

Product: molybdopterin biosynthesis MoaE protein

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MTLPPTIRVQREDFDLQAEVDRLSKNNPGVGAIVTFSGLCRDDGGTLAALELEHYPGMAEAAMTRIGELAIERFGLLGLT
AIHRYGKIAVGENIVLVVAVAPHRQAAFDGANFVMDFLKTAAPFWKKEHSRDGAEGDWVAAKDADDAARDKWK

Sequences:

>Translated_153_residues
MTLPPTIRVQREDFDLQAEVDRLSKNNPGVGAIVTFSGLCRDDGGTLAALELEHYPGMAEAAMTRIGELAIERFGLLGLT
AIHRYGKIAVGENIVLVVAVAPHRQAAFDGANFVMDFLKTAAPFWKKEHSRDGAEGDWVAAKDADDAARDKWK
>Mature_152_residues
TLPPTIRVQREDFDLQAEVDRLSKNNPGVGAIVTFSGLCRDDGGTLAALELEHYPGMAEAAMTRIGELAIERFGLLGLTA
IHRYGKIAVGENIVLVVAVAPHRQAAFDGANFVMDFLKTAAPFWKKEHSRDGAEGDWVAAKDADDAARDKWK

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Escherichia coli, GI1787003, Length=125, Percent_Identity=45.6, Blast_Score=108, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21356259, Length=119, Percent_Identity=33.6134453781513, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16664; Mature: 16533

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPPTIRVQREDFDLQAEVDRLSKNNPGVGAIVTFSGLCRDDGGTLAALELEHYPGMAE
CCCCCCEEEECCCCCHHHHHHHHCCCCCCEEEEEEECCEEECCCCEEEEEEECCCCCHHH
AAMTRIGELAIERFGLLGLTAIHRYGKIAVGENIVLVVAVAPHRQAAFDGANFVMDFLKT
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEECCCCCHHCCHHHHHHHHHHH
AAPFWKKEHSRDGAEGDWVAAKDADDAARDKWK
HCHHHHHHCCCCCCCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TLPPTIRVQREDFDLQAEVDRLSKNNPGVGAIVTFSGLCRDDGGTLAALELEHYPGMAE
CCCCCEEEECCCCCHHHHHHHHCCCCCCEEEEEEECCEEECCCCEEEEEEECCCCCHHH
AAMTRIGELAIERFGLLGLTAIHRYGKIAVGENIVLVVAVAPHRQAAFDGANFVMDFLKT
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEECCCCCHHCCHHHHHHHHHHH
AAPFWKKEHSRDGAEGDWVAAKDADDAARDKWK
HCHHHHHHCCCCCCCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]