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The map label for this gene is yheS [H]

Identifier: 209548678

GI number: 209548678

Start: 1095483

End: 1097366

Strand: Reverse

Name: yheS [H]

Synonym: Rleg2_1075

Alternate gene names: 209548678

Gene position: 1097366-1095483 (Counterclockwise)

Preceding gene: 209548679

Following gene: 209548677

Centisome position: 24.18

GC content: 62.85

Gene sequence:

>1884_bases
ATGATCACGCTCACCGATATTTCCGCCCGCATTGCCGGGCGCCTGCTTCTCGACAATGCCAGCATTTCGCTGCCTTCGGG
CACGAAGGCGGGGCTGGTCGGGCGCAACGGCGCCGGCAAGTCGACCCTGTTTCGCGTCATCACCGGCGATCTCGGCTCGG
AGACCGGATCGGTGTCGATCCCGAAGGCGGCGCGCATCGGCCAGGTGGCGCAGGAAGCGCCGGCGACTGAGGAATCCCTG
ATCGAGATCGTGCTGTCAGCAGACAAGGAACGCGCCGCCCTCGTTGCCGAGGCGGAAACGGCGACCGATCCGCACCGCAT
CGCCGAAATCCAGATGCGTCTCGTCGATATCGACGCGCATTCGGCCGAAGCGCGCGCGGCAAGCATTCTGGCCGGCCTCG
GCTTCGACCAGGCAGCGCAGGCCCGCCCCGCCTCCTCCTTCTCAGGCGGTTGGCGCATGCGCGTGGCACTGGCCGCCGTG
CTGTTTTCCGAGCCGGATCTGCTGCTGCTCGACGAACCCACAAACTATCTCGACCTCGAAGGCACGCTGTGGCTGGAAGA
TTATGTCCGGCGCTATCCGCACACGGTCATCATCATCAGCCACGATCGCGACCTCTTGAACAACGCGGTCAACGCGATCG
TCCATCTCGACCAGAAGAAGCTGACCTTCTATCGCGGCGGCTACGACCAGTTCGAGCGGCAGAAGGCGGAAGCCGACGAG
CTGCAGACCAAGGCCAAGGCCAAGAACGACGCGGCCCGCAAACATCTGCAGAGCTTCATCGATCGCTTCAAGGCCAAGGC
TTCCAAGGCCCGGCAGGCGCAATCGCGCGTCAAGGCGCTCGAGCGCATGGGAACCGTCGCCGCGGTGATCGAAGACCACG
TGCAGCCGATCACTTTCCCCGAGCCGGAAAAGCAGCCGGCCTCGCCGATCGTCGCGATCCAGAGCGGCGCCGTCGGTTAC
GAGCCCGGCAATCCGATCCTGAAGAACCTCAACCTGCGGATCGACAATGACGACCGCATCGCCCTGCTCGGCTCGAACGG
CAACGGCAAATCGACCTTCGCCAAATTCATCTCCGGCCGGCTTGCGCCGGAAAGCGGCGAAGTCAAGCTGGCGCCGAGCC
TGAAGATCGGCTTCTTCGCGCAGCATCAGCTCGACGACCTCATTCCCGAGCAATCGCCGGTCGAACATGTGCGCCGGCTG
ATGCCCGGCGCGCCGGAGCCCAAGGTGCGCGCTCGCGTCGCCCAGATGGGGCTTGCGACCGAGAAGATGGCGACAGCCGC
CAAGGATCTTTCCGGCGGCGAAAAGGCCCGCTTGTTGATGGGGCTTGCCGCCTTCAATGCGCCCAATCTGCTGATCCTCG
ACGAACCCACAAACCACCTCGATATCGATAGCCGCCGGGCGCTGATCGAGGCGCTGAACGATTACGAAGGCGCCGTCATC
CTGATCTCGCACGACCGACATCTGATCGAGGCGACGGTCGATCGGCTGTGGCTGGTCAATGGCGGCACGGTGACGACCTT
CGAAGGCGATATGGACGAATATCGCGACCTGATCGTCACATCCGGTAAAAAAAAAGAAGAAAAGCCGCAGCTGACTGAAG
ACGCGACATCGAAGGCCGACCAGCGCAAGCTCAATGCCGAACGGCGCGCCTCGCTGACCCCGCTCAAGAAAAAGATCAAC
GAAATCGAATCCTTGACGGCGAAGCTGGAGAAACAGATTCAGGCGCTTGACGCAGAACTTGCAAATCCCGCCCTTTACGA
AAAGACGCCGGCCAAGGCCGCCGAGAAGGCAAAGCAGCGCGGCGAGGCTGCAGCAAAACTGGCTGCCGCCGAGGAAGACT
GGCTGATGCTTTCGGCCGAATACGAAGAAGCTATGGCGGGATAG

Upstream 100 bases:

>100_bases
GGCCACTGAAGGCGCGGACAGCGCTCTTACGGCGACAAGCAGGCTTGTCGCGGGACGAGCGCTCTTGCCTTAGCGGGCGC
TTTCGGCCAAAACGCCGGCC

Downstream 100 bases:

>100_bases
CCACAGGCTTTATGGAAAGCGTGGCGAAGTGCCGCGGATCGGCACAATTCGAGCCACTATCAACCAATCGTTAACCATAA
TTCGAAAGGTTGCCTCAACA

Product: ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MITLTDISARIAGRLLLDNASISLPSGTKAGLVGRNGAGKSTLFRVITGDLGSETGSVSIPKAARIGQVAQEAPATEESL
IEIVLSADKERAALVAEAETATDPHRIAEIQMRLVDIDAHSAEARAASILAGLGFDQAAQARPASSFSGGWRMRVALAAV
LFSEPDLLLLDEPTNYLDLEGTLWLEDYVRRYPHTVIIISHDRDLLNNAVNAIVHLDQKKLTFYRGGYDQFERQKAEADE
LQTKAKAKNDAARKHLQSFIDRFKAKASKARQAQSRVKALERMGTVAAVIEDHVQPITFPEPEKQPASPIVAIQSGAVGY
EPGNPILKNLNLRIDNDDRIALLGSNGNGKSTFAKFISGRLAPESGEVKLAPSLKIGFFAQHQLDDLIPEQSPVEHVRRL
MPGAPEPKVRARVAQMGLATEKMATAAKDLSGGEKARLLMGLAAFNAPNLLILDEPTNHLDIDSRRALIEALNDYEGAVI
LISHDRHLIEATVDRLWLVNGGTVTTFEGDMDEYRDLIVTSGKKKEEKPQLTEDATSKADQRKLNAERRASLTPLKKKIN
EIESLTAKLEKQIQALDAELANPALYEKTPAKAAEKAKQRGEAAAKLAAAEEDWLMLSAEYEEAMAG

Sequences:

>Translated_627_residues
MITLTDISARIAGRLLLDNASISLPSGTKAGLVGRNGAGKSTLFRVITGDLGSETGSVSIPKAARIGQVAQEAPATEESL
IEIVLSADKERAALVAEAETATDPHRIAEIQMRLVDIDAHSAEARAASILAGLGFDQAAQARPASSFSGGWRMRVALAAV
LFSEPDLLLLDEPTNYLDLEGTLWLEDYVRRYPHTVIIISHDRDLLNNAVNAIVHLDQKKLTFYRGGYDQFERQKAEADE
LQTKAKAKNDAARKHLQSFIDRFKAKASKARQAQSRVKALERMGTVAAVIEDHVQPITFPEPEKQPASPIVAIQSGAVGY
EPGNPILKNLNLRIDNDDRIALLGSNGNGKSTFAKFISGRLAPESGEVKLAPSLKIGFFAQHQLDDLIPEQSPVEHVRRL
MPGAPEPKVRARVAQMGLATEKMATAAKDLSGGEKARLLMGLAAFNAPNLLILDEPTNHLDIDSRRALIEALNDYEGAVI
LISHDRHLIEATVDRLWLVNGGTVTTFEGDMDEYRDLIVTSGKKKEEKPQLTEDATSKADQRKLNAERRASLTPLKKKIN
EIESLTAKLEKQIQALDAELANPALYEKTPAKAAEKAKQRGEAAAKLAAAEEDWLMLSAEYEEAMAG
>Mature_627_residues
MITLTDISARIAGRLLLDNASISLPSGTKAGLVGRNGAGKSTLFRVITGDLGSETGSVSIPKAARIGQVAQEAPATEESL
IEIVLSADKERAALVAEAETATDPHRIAEIQMRLVDIDAHSAEARAASILAGLGFDQAAQARPASSFSGGWRMRVALAAV
LFSEPDLLLLDEPTNYLDLEGTLWLEDYVRRYPHTVIIISHDRDLLNNAVNAIVHLDQKKLTFYRGGYDQFERQKAEADE
LQTKAKAKNDAARKHLQSFIDRFKAKASKARQAQSRVKALERMGTVAAVIEDHVQPITFPEPEKQPASPIVAIQSGAVGY
EPGNPILKNLNLRIDNDDRIALLGSNGNGKSTFAKFISGRLAPESGEVKLAPSLKIGFFAQHQLDDLIPEQSPVEHVRRL
MPGAPEPKVRARVAQMGLATEKMATAAKDLSGGEKARLLMGLAAFNAPNLLILDEPTNHLDIDSRRALIEALNDYEGAVI
LISHDRHLIEATVDRLWLVNGGTVTTFEGDMDEYRDLIVTSGKKKEEKPQLTEDATSKADQRKLNAERRASLTPLKKKIN
EIESLTAKLEKQIQALDAELANPALYEKTPAKAAEKAKQRGEAAAKLAAAEEDWLMLSAEYEEAMAG

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=528, Percent_Identity=38.0681818181818, Blast_Score=376, Evalue=1e-104,
Organism=Homo sapiens, GI27881506, Length=542, Percent_Identity=36.7158671586716, Blast_Score=356, Evalue=4e-98,
Organism=Homo sapiens, GI10947137, Length=542, Percent_Identity=36.7158671586716, Blast_Score=355, Evalue=6e-98,
Organism=Homo sapiens, GI10947135, Length=537, Percent_Identity=35.9404096834264, Blast_Score=299, Evalue=6e-81,
Organism=Homo sapiens, GI69354671, Length=537, Percent_Identity=35.9404096834264, Blast_Score=299, Evalue=7e-81,
Organism=Homo sapiens, GI105990541, Length=247, Percent_Identity=27.9352226720648, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI21536376, Length=212, Percent_Identity=29.7169811320755, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI171184400, Length=264, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI150417984, Length=240, Percent_Identity=27.9166666666667, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI27881501, Length=194, Percent_Identity=29.3814432989691, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI30795238, Length=194, Percent_Identity=29.3814432989691, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789751, Length=633, Percent_Identity=41.2322274881517, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1787041, Length=524, Percent_Identity=34.5419847328244, Blast_Score=327, Evalue=2e-90,
Organism=Escherichia coli, GI1787182, Length=632, Percent_Identity=29.2721518987342, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI2367384, Length=527, Percent_Identity=29.9810246679317, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1788165, Length=180, Percent_Identity=31.6666666666667, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786319, Length=188, Percent_Identity=32.9787234042553, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081834, Length=200, Percent_Identity=29.5, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789891, Length=214, Percent_Identity=27.1028037383178, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786398, Length=204, Percent_Identity=26.9607843137255, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787164, Length=189, Percent_Identity=31.2169312169312, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081709, Length=210, Percent_Identity=25.2380952380952, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787370, Length=220, Percent_Identity=27.7272727272727, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787029, Length=236, Percent_Identity=25.8474576271186, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787758, Length=199, Percent_Identity=25.6281407035176, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=531, Percent_Identity=37.0998116760829, Blast_Score=348, Evalue=7e-96,
Organism=Caenorhabditis elegans, GI17555318, Length=522, Percent_Identity=34.6743295019157, Blast_Score=332, Evalue=4e-91,
Organism=Caenorhabditis elegans, GI17559834, Length=541, Percent_Identity=36.7837338262477, Blast_Score=330, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI115533608, Length=226, Percent_Identity=31.4159292035398, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17565586, Length=189, Percent_Identity=30.6878306878307, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=243, Percent_Identity=29.2181069958848, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533592, Length=187, Percent_Identity=32.0855614973262, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=540, Percent_Identity=37.4074074074074, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6320874, Length=528, Percent_Identity=33.3333333333333, Blast_Score=317, Evalue=5e-87,
Organism=Saccharomyces cerevisiae, GI6325030, Length=384, Percent_Identity=30.46875, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6323278, Length=403, Percent_Identity=26.302729528536, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324314, Length=508, Percent_Identity=25, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24666836, Length=528, Percent_Identity=39.9621212121212, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24642252, Length=542, Percent_Identity=37.4538745387454, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI18859989, Length=542, Percent_Identity=37.4538745387454, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24641342, Length=541, Percent_Identity=36.4140480591497, Blast_Score=345, Evalue=4e-95,
Organism=Drosophila melanogaster, GI28574150, Length=189, Percent_Identity=31.7460317460317, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007328, Length=189, Percent_Identity=31.7460317460317, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007184, Length=173, Percent_Identity=32.9479768786127, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI221500365, Length=173, Percent_Identity=32.9479768786127, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 68188; Mature: 68188

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLTDISARIAGRLLLDNASISLPSGTKAGLVGRNGAGKSTLFRVITGDLGSETGSVSI
CEEEEECHHHHHCEEEEECCCEECCCCCCCCCCCCCCCCHHHHHHEEECCCCCCCCCEEC
PKAARIGQVAQEAPATEESLIEIVLSADKERAALVAEAETATDPHRIAEIQMRLVDIDAH
CCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHEEEEECCCCCCCHHHHEEEEEEEEECCC
SAEARAASILAGLGFDQAAQARPASSFSGGWRMRVALAAVLFSEPDLLLLDEPTNYLDLE
CCHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEECC
GTLWLEDYVRRYPHTVIIISHDRDLLNNAVNAIVHLDQKKLTFYRGGYDQFERQKAEADE
CEEEHHHHHHHCCCEEEEEECCHHHHHHHHHHHEECCCHHEEEEECCHHHHHHHHHHHHH
LQTKAKAKNDAARKHLQSFIDRFKAKASKARQAQSRVKALERMGTVAAVIEDHVQPITFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EPEKQPASPIVAIQSGAVGYEPGNPILKNLNLRIDNDDRIALLGSNGNGKSTFAKFISGR
CCCCCCCCCEEEEECCCCCCCCCCHHHHCCEEEECCCCEEEEEECCCCCHHHHHHHHHCC
LAPESGEVKLAPSLKIGFFAQHQLDDLIPEQSPVEHVRRLMPGAPEPKVRARVAQMGLAT
CCCCCCCEEECCCCEEEEEHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCHH
EKMATAAKDLSGGEKARLLMGLAAFNAPNLLILDEPTNHLDIDSRRALIEALNDYEGAVI
HHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEE
LISHDRHLIEATVDRLWLVNGGTVTTFEGDMDEYRDLIVTSGKKKEEKPQLTEDATSKAD
EEECCCHHHHHHHHHEEEEECCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
QRKLNAERRASLTPLKKKINEIESLTAKLEKQIQALDAELANPALYEKTPAKAAEKAKQR
HHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHH
GEAAAKLAAAEEDWLMLSAEYEEAMAG
HHHHHHHHCCCCCEEEEEECHHHHHCC
>Mature Secondary Structure
MITLTDISARIAGRLLLDNASISLPSGTKAGLVGRNGAGKSTLFRVITGDLGSETGSVSI
CEEEEECHHHHHCEEEEECCCEECCCCCCCCCCCCCCCCHHHHHHEEECCCCCCCCCEEC
PKAARIGQVAQEAPATEESLIEIVLSADKERAALVAEAETATDPHRIAEIQMRLVDIDAH
CCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHEEEEECCCCCCCHHHHEEEEEEEEECCC
SAEARAASILAGLGFDQAAQARPASSFSGGWRMRVALAAVLFSEPDLLLLDEPTNYLDLE
CCHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEECC
GTLWLEDYVRRYPHTVIIISHDRDLLNNAVNAIVHLDQKKLTFYRGGYDQFERQKAEADE
CEEEHHHHHHHCCCEEEEEECCHHHHHHHHHHHEECCCHHEEEEECCHHHHHHHHHHHHH
LQTKAKAKNDAARKHLQSFIDRFKAKASKARQAQSRVKALERMGTVAAVIEDHVQPITFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EPEKQPASPIVAIQSGAVGYEPGNPILKNLNLRIDNDDRIALLGSNGNGKSTFAKFISGR
CCCCCCCCCEEEEECCCCCCCCCCHHHHCCEEEECCCCEEEEEECCCCCHHHHHHHHHCC
LAPESGEVKLAPSLKIGFFAQHQLDDLIPEQSPVEHVRRLMPGAPEPKVRARVAQMGLAT
CCCCCCCEEECCCCEEEEEHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCHH
EKMATAAKDLSGGEKARLLMGLAAFNAPNLLILDEPTNHLDIDSRRALIEALNDYEGAVI
HHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEE
LISHDRHLIEATVDRLWLVNGGTVTTFEGDMDEYRDLIVTSGKKKEEKPQLTEDATSKAD
EEECCCHHHHHHHHHEEEEECCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
QRKLNAERRASLTPLKKKINEIESLTAKLEKQIQALDAELANPALYEKTPAKAAEKAKQR
HHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHH
GEAAAKLAAAEEDWLMLSAEYEEAMAG
HHHHHHHHCCCCCEEEEEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]