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The map label for this gene is tas [H]

Identifier: 209548658

GI number: 209548658

Start: 1072883

End: 1073926

Strand: Reverse

Name: tas [H]

Synonym: Rleg2_1055

Alternate gene names: 209548658

Gene position: 1073926-1072883 (Counterclockwise)

Preceding gene: 209548666

Following gene: 209548657

Centisome position: 23.67

GC content: 61.78

Gene sequence:

>1044_bases
ATGAAGTACAATTCACTCGGCCGCACCGACATTTCCGTTTCAGAAATCTGCCTTGGCACCATGACCTGGGGTTCGCAGAA
CAGCGAAACCGACGCCCATGCGCAGATGGATTACGCCGTCGAAAAGGGCGTCAACTTCTTCGATACCGCCGAACTCTACC
CGACCACCCCGGTTTCGCCGGAAACGCAGGGCCGGACCGAAGACTATATCGGCAGCTGGTTCGGCAAATCAGGCAAGCGC
GGAGATATCGTGCTTGCCACCAAGGTCGCCGGCCGCGGCCGCGAGTATCTGCGCGGCGGCGAAGGTGCGGATGCCAGGAA
TATCCGGCTGGCGCTCGAGGCCAGCCTGAAGCGGCTGCGGACGGATTATGTCGACCTCTACCAGATCCACTGGCCGAACC
GCGGCCATTTCCATTTCCGCCAGAACTGGAGCTACAATCCCTTCAGCCAGGATCGCGACAAGGCCGTCGCCAATATGCTC
GACATTCTGGAAACGCTCGGCGCCCTGGTGAAGGAAGGCAAGATCCGGGCGATTGGCCTTTCCAACGAAACCACCTGGGG
CATCCAGAAATATCTGACGCTGTCGGAACAGAAGAGCCTGCCGCGCGTTGCCAGCGTCCAGAACGAATATAATCTGCTCT
ACCGCCATTTCGACCTCGATCTGGCCGAGCTCTCGCATCACGAGGATGTTGGGCTGCTCGCCTATTCGCCGCTCGCCGGC
GGCATCCTGTCGGGTAAATACGTCGATGGCGCCAGGCCGAAGGGCTCGCGCGGCTCGATCAACCACGATATCGGCGGCCG
CCTCCAGCCGCTGCAGGAGCCGGCGACCAAGGCCTATCTAGGGATCGCAGCAAGATACGGCCTCGACCCGGCGGCCATGG
CGCTCGCCTTCTGCCTGTCCAGGCCCTTCATGGCCTCGGCCATCATCGGCGCCACCTCGATGGAGCAACTGAAGGTCGAT
ATCGGCGCGGCCGACCTTACGCTTTCGGCCGAGATACTGGCGGAGATCGCCAAGGTGCATCGGCAGTATCCGCTGCCGCT
CTGA

Upstream 100 bases:

>100_bases
ACCGGCATAAAAGCCCGGTTTTTACTCTTGCGCTCCGCCAAATCCGGCCTAGATTTGCCCGGTCCTTCCCAAGGCGTCAG
CTCTCTCCCAAGGTTTTCTC

Downstream 100 bases:

>100_bases
CCCTGTTCCTCTCGTCCGGCCCGACGCGACCGATCGGCCTGCGTCGGGCTTGCATGTCCGATTGGGCTTGCCTTCCCGTG
AAAAATCCGTATAAGCCGCC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKYNSLGRTDISVSEICLGTMTWGSQNSETDAHAQMDYAVEKGVNFFDTAELYPTTPVSPETQGRTEDYIGSWFGKSGKR
GDIVLATKVAGRGREYLRGGEGADARNIRLALEASLKRLRTDYVDLYQIHWPNRGHFHFRQNWSYNPFSQDRDKAVANML
DILETLGALVKEGKIRAIGLSNETTWGIQKYLTLSEQKSLPRVASVQNEYNLLYRHFDLDLAELSHHEDVGLLAYSPLAG
GILSGKYVDGARPKGSRGSINHDIGGRLQPLQEPATKAYLGIAARYGLDPAAMALAFCLSRPFMASAIIGATSMEQLKVD
IGAADLTLSAEILAEIAKVHRQYPLPL

Sequences:

>Translated_347_residues
MKYNSLGRTDISVSEICLGTMTWGSQNSETDAHAQMDYAVEKGVNFFDTAELYPTTPVSPETQGRTEDYIGSWFGKSGKR
GDIVLATKVAGRGREYLRGGEGADARNIRLALEASLKRLRTDYVDLYQIHWPNRGHFHFRQNWSYNPFSQDRDKAVANML
DILETLGALVKEGKIRAIGLSNETTWGIQKYLTLSEQKSLPRVASVQNEYNLLYRHFDLDLAELSHHEDVGLLAYSPLAG
GILSGKYVDGARPKGSRGSINHDIGGRLQPLQEPATKAYLGIAARYGLDPAAMALAFCLSRPFMASAIIGATSMEQLKVD
IGAADLTLSAEILAEIAKVHRQYPLPL
>Mature_347_residues
MKYNSLGRTDISVSEICLGTMTWGSQNSETDAHAQMDYAVEKGVNFFDTAELYPTTPVSPETQGRTEDYIGSWFGKSGKR
GDIVLATKVAGRGREYLRGGEGADARNIRLALEASLKRLRTDYVDLYQIHWPNRGHFHFRQNWSYNPFSQDRDKAVANML
DILETLGALVKEGKIRAIGLSNETTWGIQKYLTLSEQKSLPRVASVQNEYNLLYRHFDLDLAELSHHEDVGLLAYSPLAG
GILSGKYVDGARPKGSRGSINHDIGGRLQPLQEPATKAYLGIAARYGLDPAAMALAFCLSRPFMASAIIGATSMEQLKVD
IGAADLTLSAEILAEIAKVHRQYPLPL

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=355, Percent_Identity=29.8591549295775, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI27436962, Length=355, Percent_Identity=29.5774647887324, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436966, Length=355, Percent_Identity=29.2957746478873, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436969, Length=355, Percent_Identity=29.0140845070423, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4504825, Length=353, Percent_Identity=28.6118980169972, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI27436971, Length=347, Percent_Identity=28.5302593659942, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI223718702, Length=331, Percent_Identity=26.2839879154079, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI41327764, Length=242, Percent_Identity=28.099173553719, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI41152114, Length=249, Percent_Identity=27.3092369477912, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1789199, Length=352, Percent_Identity=47.1590909090909, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI87081735, Length=359, Percent_Identity=31.4763231197772, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788070, Length=357, Percent_Identity=29.1316526610644, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789375, Length=352, Percent_Identity=28.125, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17564128, Length=318, Percent_Identity=27.6729559748428, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323998, Length=339, Percent_Identity=27.4336283185841, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319958, Length=317, Percent_Identity=24.6056782334385, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319951, Length=339, Percent_Identity=24.188790560472, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=261, Percent_Identity=23.7547892720307, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=372, Percent_Identity=24.1935483870968, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324694, Length=341, Percent_Identity=25.2199413489736, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646155, Length=336, Percent_Identity=25.297619047619, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38283; Mature: 38283

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYNSLGRTDISVSEICLGTMTWGSQNSETDAHAQMDYAVEKGVNFFDTAELYPTTPVSP
CCCCCCCCCCCCHHHHHEEEECCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCC
ETQGRTEDYIGSWFGKSGKRGDIVLATKVAGRGREYLRGGEGADARNIRLALEASLKRLR
CCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCEEEHHHHHHHHHH
TDYVDLYQIHWPNRGHFHFRQNWSYNPFSQDRDKAVANMLDILETLGALVKEGKIRAIGL
HHHEEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
SNETTWGIQKYLTLSEQKSLPRVASVQNEYNLLYRHFDLDLAELSHHEDVGLLAYSPLAG
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEECCCCC
GILSGKYVDGARPKGSRGSINHDIGGRLQPLQEPATKAYLGIAARYGLDPAAMALAFCLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
RPFMASAIIGATSMEQLKVDIGAADLTLSAEILAEIAKVHRQYPLPL
CCHHHHHHHCCCCHHHHEEECCCCCEEHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKYNSLGRTDISVSEICLGTMTWGSQNSETDAHAQMDYAVEKGVNFFDTAELYPTTPVSP
CCCCCCCCCCCCHHHHHEEEECCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCC
ETQGRTEDYIGSWFGKSGKRGDIVLATKVAGRGREYLRGGEGADARNIRLALEASLKRLR
CCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCEEEHHHHHHHHHH
TDYVDLYQIHWPNRGHFHFRQNWSYNPFSQDRDKAVANMLDILETLGALVKEGKIRAIGL
HHHEEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
SNETTWGIQKYLTLSEQKSLPRVASVQNEYNLLYRHFDLDLAELSHHEDVGLLAYSPLAG
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEECCCCC
GILSGKYVDGARPKGSRGSINHDIGGRLQPLQEPATKAYLGIAARYGLDPAAMALAFCLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
RPFMASAIIGATSMEQLKVDIGAADLTLSAEILAEIAKVHRQYPLPL
CCHHHHHHHCCCCHHHHEEECCCCCEEHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]