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The map label for this gene is yhdN [H]

Identifier: 209548607

GI number: 209548607

Start: 1025909

End: 1026904

Strand: Direct

Name: yhdN [H]

Synonym: Rleg2_1004

Alternate gene names: 209548607

Gene position: 1025909-1026904 (Clockwise)

Preceding gene: 209548606

Following gene: 209548611

Centisome position: 22.61

GC content: 64.56

Gene sequence:

>996_bases
ATGCTGACCAAGACCGCAACACCGACCACGATCACGCTCTGGAACGGCCGCGAAATTCCGCGTCTCGGCATGGGATGCTG
GGCGATCGGCGGCCCCTTCTTTGCCGGCGACACGCCGCTCGGCTGGGGCGAAGTCGACGACGATGAATCCGTCGAAGCGA
TCGGCAGCGCCATCGACCTCGGCATCCGCTTCTTCGATACCGCCTCGAATTACGGCGCCGGCCATTCCGAAGAAGTGCTC
GGCCGGGCGATCGGCAATCGCGACGATATTATTGTTGCCACCAAATTCGGCTTTGCCACCGATGCCGCCACCAAGCAGGC
TACCGGCGCCTTTGCCGATGAAGCCTTCATCCGCCGTTCGGTCGAGACCTCGCTGCGCCGCCTCAAGCGTGACCGCCTCG
ATCTCCTACAGTTCCACATCAATGATTTTCCGTTGGAACAGTCCGATGCCGTCTTCGACGTGCTGGAGGCGTTGCGCGTC
GAAGGCAAGATCGACGCATTCGGCTGGAGCACCGATTCTCCCGATCGCGCCGCCCGCCATGCCGGCCGCCAGGGCTATGT
CTCGGTGCAGCATACGATGAACGTCTTCGAGCCGGTGCCGGAGATGATCGCAGTGATCGAAAGGCAGGAACTGATCTCGA
TCAATCGCGGTCCGCTGGCCATGGGGCTGCTGACCGGCAAGTTCACCGCCGACAAGGCGGTGGGCGCCAAGGATGTCCGC
GGCGCGGCCCTCGACTGGATGGTCTACTTCAAGGACGGGCGCATGGCCCCGGAATTTGCCGCAAGGCTCGACGCCGTCCG
CGATCTCCTGACCTCGGGCGGCCGCACACTGACGCAAGGGGCGCTCGCCTGGCTCTGGGCAAAGTCGCCGCGCACCCTCC
CCATTCCAGGCTTCCGCACCGTCGCCCAGGTGGAGGAAAATGCCGGCGCACTGGAAAAGGGACCGCTGCCGGCCGATGTC
ATGGCGGGGATCGACGCCGCACTCGGGCATCAGTGA

Upstream 100 bases:

>100_bases
CTCGGTTTTTTACCGGTGCAAAACATCCTCCGGATTTGGCGGTTTACCCGCATGGGAGCCCTTCCTATGTCTTGGAAGAC
TGCCAGCCAAGGAGGATCCC

Downstream 100 bases:

>100_bases
GAGTCGGTGACGCTCCCCCACGCTCCCTCATTCCTGTGCTCGTCACAGGAAACCAGCCACCGCGCGTCTGCGCGGTGAAT
GACTCAATGCGAATTTGAAA

Product: aldo/keto reductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MLTKTATPTTITLWNGREIPRLGMGCWAIGGPFFAGDTPLGWGEVDDDESVEAIGSAIDLGIRFFDTASNYGAGHSEEVL
GRAIGNRDDIIVATKFGFATDAATKQATGAFADEAFIRRSVETSLRRLKRDRLDLLQFHINDFPLEQSDAVFDVLEALRV
EGKIDAFGWSTDSPDRAARHAGRQGYVSVQHTMNVFEPVPEMIAVIERQELISINRGPLAMGLLTGKFTADKAVGAKDVR
GAALDWMVYFKDGRMAPEFAARLDAVRDLLTSGGRTLTQGALAWLWAKSPRTLPIPGFRTVAQVEENAGALEKGPLPADV
MAGIDAALGHQ

Sequences:

>Translated_331_residues
MLTKTATPTTITLWNGREIPRLGMGCWAIGGPFFAGDTPLGWGEVDDDESVEAIGSAIDLGIRFFDTASNYGAGHSEEVL
GRAIGNRDDIIVATKFGFATDAATKQATGAFADEAFIRRSVETSLRRLKRDRLDLLQFHINDFPLEQSDAVFDVLEALRV
EGKIDAFGWSTDSPDRAARHAGRQGYVSVQHTMNVFEPVPEMIAVIERQELISINRGPLAMGLLTGKFTADKAVGAKDVR
GAALDWMVYFKDGRMAPEFAARLDAVRDLLTSGGRTLTQGALAWLWAKSPRTLPIPGFRTVAQVEENAGALEKGPLPADV
MAGIDAALGHQ
>Mature_331_residues
MLTKTATPTTITLWNGREIPRLGMGCWAIGGPFFAGDTPLGWGEVDDDESVEAIGSAIDLGIRFFDTASNYGAGHSEEVL
GRAIGNRDDIIVATKFGFATDAATKQATGAFADEAFIRRSVETSLRRLKRDRLDLLQFHINDFPLEQSDAVFDVLEALRV
EGKIDAFGWSTDSPDRAARHAGRQGYVSVQHTMNVFEPVPEMIAVIERQELISINRGPLAMGLLTGKFTADKAVGAKDVR
GAALDWMVYFKDGRMAPEFAARLDAVRDLLTSGGRTLTQGALAWLWAKSPRTLPIPGFRTVAQVEENAGALEKGPLPADV
MAGIDAALGHQ

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Escherichia coli, GI87081735, Length=317, Percent_Identity=31.5457413249211, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788070, Length=308, Percent_Identity=27.9220779220779, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789375, Length=337, Percent_Identity=25.5192878338279, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI48994888, Length=295, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35818; Mature: 35818

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKTATPTTITLWNGREIPRLGMGCWAIGGPFFAGDTPLGWGEVDDDESVEAIGSAIDL
CCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
GIRFFDTASNYGAGHSEEVLGRAIGNRDDIIVATKFGFATDAATKQATGAFADEAFIRRS
CCCEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCCHHHHHHHHHH
VETSLRRLKRDRLDLLQFHINDFPLEQSDAVFDVLEALRVEGKIDAFGWSTDSPDRAARH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHH
AGRQGYVSVQHTMNVFEPVPEMIAVIERQELISINRGPLAMGLLTGKFTADKAVGAKDVR
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHCC
GAALDWMVYFKDGRMAPEFAARLDAVRDLLTSGGRTLTQGALAWLWAKSPRTLPIPGFRT
CCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHEEECCCCCCCCCCCCHH
VAQVEENAGALEKGPLPADVMAGIDAALGHQ
HHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTKTATPTTITLWNGREIPRLGMGCWAIGGPFFAGDTPLGWGEVDDDESVEAIGSAIDL
CCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
GIRFFDTASNYGAGHSEEVLGRAIGNRDDIIVATKFGFATDAATKQATGAFADEAFIRRS
CCCEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCCHHHHHHHHHH
VETSLRRLKRDRLDLLQFHINDFPLEQSDAVFDVLEALRVEGKIDAFGWSTDSPDRAARH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHH
AGRQGYVSVQHTMNVFEPVPEMIAVIERQELISINRGPLAMGLLTGKFTADKAVGAKDVR
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHCC
GAALDWMVYFKDGRMAPEFAARLDAVRDLLTSGGRTLTQGALAWLWAKSPRTLPIPGFRT
CCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHEEECCCCCCCCCCCCHH
VAQVEENAGALEKGPLPADVMAGIDAALGHQ
HHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]