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The map label for this gene is lepB [H]

Identifier: 209548600

GI number: 209548600

Start: 1019938

End: 1020681

Strand: Direct

Name: lepB [H]

Synonym: Rleg2_0997

Alternate gene names: 209548600

Gene position: 1019938-1020681 (Clockwise)

Preceding gene: 209548599

Following gene: 209548601

Centisome position: 22.48

GC content: 57.8

Gene sequence:

>744_bases
GTGTCCGAAAAAGTCGAAGCCAAGCCGAACGCCCTCTGGGAAAATATCAAAGTCATCATCCAGGCGCTGATTTTGGCGAT
GGTGATCCGTACGGTGCTGTTCCAGCCCTTTACCATTCCGTCCGGTTCGATGATGCCGACGCTGCTCGTCGGCGATTACA
TCTTCGTCAATAAGTTCGCCTACGGCTATTCGAAATATTCGCTGCCCTTCTCGCCAGACATCTTCAGCGGCCGTCTGTTC
GGCGCCGATCCGAAGCGCGGCGATATCGTCGTCTTCCGCTTCCCGCCTAACCCCGAGATCGACTACATCAAGCGCTGCAT
CGGCCTGCCGGGCGACCACATCCAGGTCACCGACGGCGTGCTCTATGTCAATGGAAAGCCGGTTCCGAAGGTAGCGGACG
GTACCTTCACCTCGGATTACAAGCTCGATCCGGGTGCGGATGTGCCGGTGTTCCGCGAAACGCTCGACAATGGCAAGACT
TACGACACGCTCGATCAGTCTCCCGTGTCGCGCGGCGACAACACCCGTGAATTCATCGTGCCGGAAGGCCATTATTTCAT
GATGGGCGACAACCGCGACAACTCGCTCGACAGCCGCTTCGACGTTGGCTTCGTGCCTGCGGAAAATCTTGTCGGCCGCG
CCAGCGTCATCTTCTTCTCGCTCGGCAACGACACCTCCTTCCGCGAAATCTGGAAGTGGCCGACGAACATGCGCTGGGAT
CGCCTCTTCAAGGTTGTTGAATGA

Upstream 100 bases:

>100_bases
TCGCTTTTGGCGTTGTCACCATTGCCGCAACCGGCCGAAGTCGCTAGAGAGAACGACAGAAGAATTGCGCCGCCGCGGCG
TCTTGAAGGAATAAGACTGC

Downstream 100 bases:

>100_bases
GCAAGGCGCAGACGCTTTCTGCGGCAGACCGCGCAAAGCTTGAAGGCCTGATCGGTCACGACTTCGCCGAAAAGGAACGC
CTGGACCGGGCGCTGACCCA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSEKVEAKPNALWENIKVIIQALILAMVIRTVLFQPFTIPSGSMMPTLLVGDYIFVNKFAYGYSKYSLPFSPDIFSGRLF
GADPKRGDIVVFRFPPNPEIDYIKRCIGLPGDHIQVTDGVLYVNGKPVPKVADGTFTSDYKLDPGADVPVFRETLDNGKT
YDTLDQSPVSRGDNTREFIVPEGHYFMMGDNRDNSLDSRFDVGFVPAENLVGRASVIFFSLGNDTSFREIWKWPTNMRWD
RLFKVVE

Sequences:

>Translated_247_residues
MSEKVEAKPNALWENIKVIIQALILAMVIRTVLFQPFTIPSGSMMPTLLVGDYIFVNKFAYGYSKYSLPFSPDIFSGRLF
GADPKRGDIVVFRFPPNPEIDYIKRCIGLPGDHIQVTDGVLYVNGKPVPKVADGTFTSDYKLDPGADVPVFRETLDNGKT
YDTLDQSPVSRGDNTREFIVPEGHYFMMGDNRDNSLDSRFDVGFVPAENLVGRASVIFFSLGNDTSFREIWKWPTNMRWD
RLFKVVE
>Mature_246_residues
SEKVEAKPNALWENIKVIIQALILAMVIRTVLFQPFTIPSGSMMPTLLVGDYIFVNKFAYGYSKYSLPFSPDIFSGRLFG
ADPKRGDIVVFRFPPNPEIDYIKRCIGLPGDHIQVTDGVLYVNGKPVPKVADGTFTSDYKLDPGADVPVFRETLDNGKTY
DTLDQSPVSRGDNTREFIVPEGHYFMMGDNRDNSLDSRFDVGFVPAENLVGRASVIFFSLGNDTSFREIWKWPTNMRWDR
LFKVVE

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=283, Percent_Identity=36.0424028268551, Blast_Score=149, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 27940; Mature: 27809

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00501 SPASE_I_1 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKVEAKPNALWENIKVIIQALILAMVIRTVLFQPFTIPSGSMMPTLLVGDYIFVNKFA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCEEHHHH
YGYSKYSLPFSPDIFSGRLFGADPKRGDIVVFRFPPNPEIDYIKRCIGLPGDHIQVTDGV
HCCEECCCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCE
LYVNGKPVPKVADGTFTSDYKLDPGADVPVFRETLDNGKTYDTLDQSPVSRGDNTREFIV
EEECCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEE
PEGHYFMMGDNRDNSLDSRFDVGFVPAENLVGRASVIFFSLGNDTSFREIWKWPTNMRWD
CCCCEEEEECCCCCCCCCCCCEEECCHHHHCCCEEEEEEECCCCCCHHHHHCCCCCCCHH
RLFKVVE
HHHHHCC
>Mature Secondary Structure 
SEKVEAKPNALWENIKVIIQALILAMVIRTVLFQPFTIPSGSMMPTLLVGDYIFVNKFA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCEEHHHH
YGYSKYSLPFSPDIFSGRLFGADPKRGDIVVFRFPPNPEIDYIKRCIGLPGDHIQVTDGV
HCCEECCCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCE
LYVNGKPVPKVADGTFTSDYKLDPGADVPVFRETLDNGKTYDTLDQSPVSRGDNTREFIV
EEECCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEE
PEGHYFMMGDNRDNSLDSRFDVGFVPAENLVGRASVIFFSLGNDTSFREIWKWPTNMRWD
CCCCEEEEECCCCCCCCCCCCEEECCHHHHCCCEEEEEEECCCCCCHHHHHCCCCCCCHH
RLFKVVE
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA