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The map label for this gene is hisC [H]

Identifier: 209548570

GI number: 209548570

Start: 989903

End: 991015

Strand: Reverse

Name: hisC [H]

Synonym: Rleg2_0967

Alternate gene names: 209548570

Gene position: 991015-989903 (Counterclockwise)

Preceding gene: 209548571

Following gene: 209548568

Centisome position: 21.84

GC content: 65.41

Gene sequence:

>1113_bases
ATGTCCGCCTTTTCGCGCTTCACGCCTCTTGCCGGCGCCCTGCCCTCCACCGTTCCTTTCGTCGGTCCCGAGGCGATCGA
GCGCCAGCGCGGGTTTGCCGTTTCGGCTCGCATCGGCGCCAATGAGAACGGCTTCGGTCCCGCCCCTTCCGTGTTTGCGG
CGATGCGCGAAGAGGCCGGCAATATCTGGAAATACAATGACCCGGAGAATTTCGCGCTCCGGCAAGCGCTTGGTGACCAT
CTCGGCGTCCCCTCTGCCAATATCGCCATCGGCAGCGGCATCGACGAGCTGCTCGGCCAGATCGTCCGGCTGGTGATCGA
GCCCGGCGCTCCCGTCGTCACCTCGCTCGGCGCCTATCCGACCTTCAATTTCCACGTTGCCGGCTTCGGCGGTCGGCTTG
TGACCGTTCCCTACGCCAACGACCGCGAGGATCTCGACGGCTTGCTCGATGCCGTCAAGCGGGAGAATGCACCGCTGGTC
TATTTCGCCAATCCCGACAATCCGATGGGAAGCTGGTGGGATGCCGACAAGATCGTCGCCTTCGCCCGGGCGCTGCCCGA
GACGACGCTGATGGTGCTCGACGAAGCCTATAGCGAAACGGGGCCGGCAGGCGCGCTGCCATCGATCGCCTCGCTGATCG
AGCTGCCGAACGTCGTTCGCACCCGCACCTTTTCCAAGGCCTACGGACTGGCCGGCTCACGCACCGGTTACGTGATCTCG
ACGGCCGGAACGGCTGAAGCTTTCGACAAGATCCGCAATCATTTCGGCATGAACCGGCTGGCGACGGCGGCAGCCCTCGC
CGCTCTCAAGGACCAGGCCTATCTCGCCGAGGTGGTCGGGAAAATCCAGGCGGCGCGGGAGCGTATCGGCGGCATCGCCC
GGGCAAACGGCTTTGAGCCCCTGCCCTCGGCAACGAATTTCGTGGCGATCGATGCCGGCCGGGACGGCGCCTATGCGCGG
GCGATCGTCGACGGGCTGATGGAACGCGGCGTTTTCATCCGCATGCCCGGCGTGGCGCCCCTCAATCGCTGCATTCGCGT
CAGCGTCGGGCCGGAGGCGGATATGGCGCTGTTCGAAGACGCGCTGCCGCAGGTGCTGAAACAGATCGGCTGA

Upstream 100 bases:

>100_bases
GCCGGCAGCCAGTCGATTGCAGAAATAATCTTGCTTGCGTCGGTGGTGCCCGGGCCTATTGTTGCGCCGATCGTCAACAT
ATCCGGGAAATCGCCTTCGC

Downstream 100 bases:

>100_bases
TAAAAGCGTCAGCGGAAACAACTAGAACCGCGGCCGGTGGAGGATCCGGCCGCGGTTCCGTTCTCCTGGCGTCGGGCCTG
TTGAAAGCGCCCTGCCGGCT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSAFSRFTPLAGALPSTVPFVGPEAIERQRGFAVSARIGANENGFGPAPSVFAAMREEAGNIWKYNDPENFALRQALGDH
LGVPSANIAIGSGIDELLGQIVRLVIEPGAPVVTSLGAYPTFNFHVAGFGGRLVTVPYANDREDLDGLLDAVKRENAPLV
YFANPDNPMGSWWDADKIVAFARALPETTLMVLDEAYSETGPAGALPSIASLIELPNVVRTRTFSKAYGLAGSRTGYVIS
TAGTAEAFDKIRNHFGMNRLATAAALAALKDQAYLAEVVGKIQAARERIGGIARANGFEPLPSATNFVAIDAGRDGAYAR
AIVDGLMERGVFIRMPGVAPLNRCIRVSVGPEADMALFEDALPQVLKQIG

Sequences:

>Translated_370_residues
MSAFSRFTPLAGALPSTVPFVGPEAIERQRGFAVSARIGANENGFGPAPSVFAAMREEAGNIWKYNDPENFALRQALGDH
LGVPSANIAIGSGIDELLGQIVRLVIEPGAPVVTSLGAYPTFNFHVAGFGGRLVTVPYANDREDLDGLLDAVKRENAPLV
YFANPDNPMGSWWDADKIVAFARALPETTLMVLDEAYSETGPAGALPSIASLIELPNVVRTRTFSKAYGLAGSRTGYVIS
TAGTAEAFDKIRNHFGMNRLATAAALAALKDQAYLAEVVGKIQAARERIGGIARANGFEPLPSATNFVAIDAGRDGAYAR
AIVDGLMERGVFIRMPGVAPLNRCIRVSVGPEADMALFEDALPQVLKQIG
>Mature_369_residues
SAFSRFTPLAGALPSTVPFVGPEAIERQRGFAVSARIGANENGFGPAPSVFAAMREEAGNIWKYNDPENFALRQALGDHL
GVPSANIAIGSGIDELLGQIVRLVIEPGAPVVTSLGAYPTFNFHVAGFGGRLVTVPYANDREDLDGLLDAVKRENAPLVY
FANPDNPMGSWWDADKIVAFARALPETTLMVLDEAYSETGPAGALPSIASLIELPNVVRTRTFSKAYGLAGSRTGYVIST
AGTAEAFDKIRNHFGMNRLATAAALAALKDQAYLAEVVGKIQAARERIGGIARANGFEPLPSATNFVAIDAGRDGAYARA
IVDGLMERGVFIRMPGVAPLNRCIRVSVGPEADMALFEDALPQVLKQIG

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=308, Percent_Identity=26.6233766233766, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322075, Length=348, Percent_Identity=24.4252873563218, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39203; Mature: 39072

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFSRFTPLAGALPSTVPFVGPEAIERQRGFAVSARIGANENGFGPAPSVFAAMREEAG
CCCHHHCCCHHCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCC
NIWKYNDPENFALRQALGDHLGVPSANIAIGSGIDELLGQIVRLVIEPGAPVVTSLGAYP
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCHHHHCCCCC
TFNFHVAGFGGRLVTVPYANDREDLDGLLDAVKRENAPLVYFANPDNPMGSWWDADKIVA
CCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHH
FARALPETTLMVLDEAYSETGPAGALPSIASLIELPNVVRTRTFSKAYGLAGSRTGYVIS
HHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEE
TAGTAEAFDKIRNHFGMNRLATAAALAALKDQAYLAEVVGKIQAARERIGGIARANGFEP
CCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCC
LPSATNFVAIDAGRDGAYARAIVDGLMERGVFIRMPGVAPLNRCIRVSVGPEADMALFED
CCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCHHCCEEEEECCCCHHHHHHHH
ALPQVLKQIG
HHHHHHHHCC
>Mature Secondary Structure 
SAFSRFTPLAGALPSTVPFVGPEAIERQRGFAVSARIGANENGFGPAPSVFAAMREEAG
CCHHHCCCHHCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCC
NIWKYNDPENFALRQALGDHLGVPSANIAIGSGIDELLGQIVRLVIEPGAPVVTSLGAYP
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCHHHHCCCCC
TFNFHVAGFGGRLVTVPYANDREDLDGLLDAVKRENAPLVYFANPDNPMGSWWDADKIVA
CCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHH
FARALPETTLMVLDEAYSETGPAGALPSIASLIELPNVVRTRTFSKAYGLAGSRTGYVIS
HHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEE
TAGTAEAFDKIRNHFGMNRLATAAALAALKDQAYLAEVVGKIQAARERIGGIARANGFEP
CCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCC
LPSATNFVAIDAGRDGAYARAIVDGLMERGVFIRMPGVAPLNRCIRVSVGPEADMALFED
CCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCHHCCEEEEECCCCHHHHHHHH
ALPQVLKQIG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA