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The map label for this gene is pleC [H]

Identifier: 209548532

GI number: 209548532

Start: 946063

End: 948372

Strand: Reverse

Name: pleC [H]

Synonym: Rleg2_0929

Alternate gene names: 209548532

Gene position: 948372-946063 (Counterclockwise)

Preceding gene: 209548533

Following gene: 209548512

Centisome position: 20.9

GC content: 64.42

Gene sequence:

>2310_bases
ATGATGGACGTGCGGCGGGCAACCGTGGCCGGAGGACGGCTGCGTGTCGATTTTGACGGGTTGAAAGCCTGGCGAGACAG
CCTTTCCGGTCATGCGACATCGGAACCACTTCTCCGTCATCTGCCGAAGGCGGAACTGCTGTTGAAGCGCGCCATTCCGG
CGCTGATCGTCGCCTTCCTCTTTGTCGTCGCCGCCTCGCATTTCTTCGGCATGGTCAGCGAATACTCCCGCCTGGAAGCC
TCTGCCCGCCATGCCACCGCGCTTTCGGCCGCGACCGCTTCTGCGGTGTTTGCCGATACATCCGAGATTTTCGACAGCGG
CGATATCGCAGAAGCGCAGGCCCGGCTCGCCAGGTTCCTGCCGCAGGACCGGCTCGACAGCGGCGCCTTCGTGCTGCTCG
TCCAGGCAAGCGGCAAGGTCTTTGCCGCAACGACCGCCGGACTTTCGCATGTCGGCAGCAATGTCGGCGATTTCTTTCCC
GAGGTCTCGGCGATCCGGCGTTTCGGCGATCGCGCCGGCGTCATCGAAACGACGATCGGCGGCGTGCCGCACTATGCCGA
GATCACGCTGATGGGCAATGCCGGCGGTTATATCGTCGCCGCCACCTCGCTCGACGAGATCAGCCGCCTCTGGCGCGAGC
AGCTCGCCCTCAACGTGACGCTGTTTGCCGGCATCTCCTCGATCCTGCTGGTCATCCTCTATGCCTACTACACGCAGGTG
AAGCGCGCCCGCGACGCCGACGACATCTTCCTGGAATCGAACCTGCGCGTCGAGACGGCGCTGTCGCGCGGCCGCTGCGG
CCTTTGGGACTTCGATTTCGAGAACCGCGAATTCTTCTGGTCGCGCTCGATGTACGATATGCTCGGCCTGCCGGGGTCCG
ACAAGACGATGGGCTTCGGCGAAGCCGCCCGGCTGATGCATCCCGATGACGGCGGGCTCTACGAGATCGCGCGCGCCATC
GCCAAGGGCCACTCCGGCCAGGTCGATCAGATCTTCCGCATGCGCCATGCCGGCGGTCACTATGTCTGGATGCGCGCCCG
CGCCCAGGTCATCCGCAGCAACTCCGGCCGCGTGCACCTGATCGGCATCGCCATGGACGTGACCGAACAGCATCGGCTTG
CCCAGCGCTACGCCGAAGCCGACCAGCGCCTTGCCGACGCCATCGAATGCACCTCGGAAGCCTTCGTGCTCTGGGACAAG
AACGATCGGCTGGTCATGTGCAACACCCATTTCCAGCAGGCTTACGGCCTGCCGGACAGCGTGCTGGTGCCCGGCACCGA
GCGCTCGATCGTCAATGCCGCCGCTGCCCGCCCCGTCATCGAACGGCGGATCGCCGATGCCGACGGCCCCGGCTATTCGC
GCACGACCGAGGTGCAGCTTGCCGACGAGCGCTGGCTGCAGATCAATGAGCGGCGCACCCGCGACGGCGGCAGGGTCTCT
GTGGGAACCGACATCACCCTGATGAAGCGCCATCAGGAGCGGCTGCGCGAATCTGAACGCCGGCTGATGGCGACGATCGG
CGATCTCTCGGCCTCGCGCCAGACGCTGGAGATCCAGAAATCCGAGCTTTCGACGGCGAACGCCAACTACCAGGCGGAAA
AAGAGCGCGCCGAGGCCGCCAACAAGGCGAAATCGGAATTCCTCGCCAATATGTCGCATGAGCTGCGCACGCCACTCAAC
GCCATCCTCGGCTTCTCGGAAATCCTGCAGAACCAGATGTTCGGACCGCTCGGCTCGCTGAAATACGACGAATATGCCCG
CGACATCCATGACAGCGGCAAACATCTGCTCAACGTCATCAACGACATTCTCGATATGTCGAAGATCGAAGCCGGCCATC
TCAGGCTGCACTGCGAGCGCATCGATCTGGTGCCGCTGATCGAGGAAAGCCTGCGCTTCACCGCCATTCCGGCTGCCGAG
AAGAACATCGTCATCGACCAGCGCATCTCCTCCGGCCTGACGCTGACGGCCGACCGCCGGGCGATGAAGCAGGTGCTTCT
CAACCTGCTCTCCAATGCGGTGAAGTTCACCGACAATGGCGGCCGCATCGCGGTGCGCACACGCCGCATCGACGGCGCCG
TCCTCGTCACCATCGCCGACACCGGCATCGGCATTCCCCGCTCGGCGCTGTCGAAGATCGGCCAGCCCTTCGAACAGGTG
CAGAGCCAGTATGCCAAGAGCAAGGGCGGCTCCGGCCTGGGCCTCGCCATTTCCCGCTCGCTGACCGCGCTGCATGGCGG
CCGCATGAAGATCCGCTCCCGCGAAGCCGTGGGCACGGTGATCTCGCTGCGCATTCCGGACGATGTTTAG

Upstream 100 bases:

>100_bases
GATTTTTACCTTTGCCTCTGGACAAGGCGAATCACCCATGATTCTCTAGGTCAGGTTCGAGCGAGCGGCGCGCGAATCAC
ACGAGGGACAAGGCGAAGAG

Downstream 100 bases:

>100_bases
ACGTTGCTAGCTGCGTCGGCCTAAATCGGCAGACGGCGAGACACCGAAATGCGACCGGTATTCGGCGGAAAACCGTCCCA
TGTGGACAAATCCCCACTGC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 769; Mature: 769

Protein sequence:

>769_residues
MMDVRRATVAGGRLRVDFDGLKAWRDSLSGHATSEPLLRHLPKAELLLKRAIPALIVAFLFVVAASHFFGMVSEYSRLEA
SARHATALSAATASAVFADTSEIFDSGDIAEAQARLARFLPQDRLDSGAFVLLVQASGKVFAATTAGLSHVGSNVGDFFP
EVSAIRRFGDRAGVIETTIGGVPHYAEITLMGNAGGYIVAATSLDEISRLWREQLALNVTLFAGISSILLVILYAYYTQV
KRARDADDIFLESNLRVETALSRGRCGLWDFDFENREFFWSRSMYDMLGLPGSDKTMGFGEAARLMHPDDGGLYEIARAI
AKGHSGQVDQIFRMRHAGGHYVWMRARAQVIRSNSGRVHLIGIAMDVTEQHRLAQRYAEADQRLADAIECTSEAFVLWDK
NDRLVMCNTHFQQAYGLPDSVLVPGTERSIVNAAAARPVIERRIADADGPGYSRTTEVQLADERWLQINERRTRDGGRVS
VGTDITLMKRHQERLRESERRLMATIGDLSASRQTLEIQKSELSTANANYQAEKERAEAANKAKSEFLANMSHELRTPLN
AILGFSEILQNQMFGPLGSLKYDEYARDIHDSGKHLLNVINDILDMSKIEAGHLRLHCERIDLVPLIEESLRFTAIPAAE
KNIVIDQRISSGLTLTADRRAMKQVLLNLLSNAVKFTDNGGRIAVRTRRIDGAVLVTIADTGIGIPRSALSKIGQPFEQV
QSQYAKSKGGSGLGLAISRSLTALHGGRMKIRSREAVGTVISLRIPDDV

Sequences:

>Translated_769_residues
MMDVRRATVAGGRLRVDFDGLKAWRDSLSGHATSEPLLRHLPKAELLLKRAIPALIVAFLFVVAASHFFGMVSEYSRLEA
SARHATALSAATASAVFADTSEIFDSGDIAEAQARLARFLPQDRLDSGAFVLLVQASGKVFAATTAGLSHVGSNVGDFFP
EVSAIRRFGDRAGVIETTIGGVPHYAEITLMGNAGGYIVAATSLDEISRLWREQLALNVTLFAGISSILLVILYAYYTQV
KRARDADDIFLESNLRVETALSRGRCGLWDFDFENREFFWSRSMYDMLGLPGSDKTMGFGEAARLMHPDDGGLYEIARAI
AKGHSGQVDQIFRMRHAGGHYVWMRARAQVIRSNSGRVHLIGIAMDVTEQHRLAQRYAEADQRLADAIECTSEAFVLWDK
NDRLVMCNTHFQQAYGLPDSVLVPGTERSIVNAAAARPVIERRIADADGPGYSRTTEVQLADERWLQINERRTRDGGRVS
VGTDITLMKRHQERLRESERRLMATIGDLSASRQTLEIQKSELSTANANYQAEKERAEAANKAKSEFLANMSHELRTPLN
AILGFSEILQNQMFGPLGSLKYDEYARDIHDSGKHLLNVINDILDMSKIEAGHLRLHCERIDLVPLIEESLRFTAIPAAE
KNIVIDQRISSGLTLTADRRAMKQVLLNLLSNAVKFTDNGGRIAVRTRRIDGAVLVTIADTGIGIPRSALSKIGQPFEQV
QSQYAKSKGGSGLGLAISRSLTALHGGRMKIRSREAVGTVISLRIPDDV
>Mature_769_residues
MMDVRRATVAGGRLRVDFDGLKAWRDSLSGHATSEPLLRHLPKAELLLKRAIPALIVAFLFVVAASHFFGMVSEYSRLEA
SARHATALSAATASAVFADTSEIFDSGDIAEAQARLARFLPQDRLDSGAFVLLVQASGKVFAATTAGLSHVGSNVGDFFP
EVSAIRRFGDRAGVIETTIGGVPHYAEITLMGNAGGYIVAATSLDEISRLWREQLALNVTLFAGISSILLVILYAYYTQV
KRARDADDIFLESNLRVETALSRGRCGLWDFDFENREFFWSRSMYDMLGLPGSDKTMGFGEAARLMHPDDGGLYEIARAI
AKGHSGQVDQIFRMRHAGGHYVWMRARAQVIRSNSGRVHLIGIAMDVTEQHRLAQRYAEADQRLADAIECTSEAFVLWDK
NDRLVMCNTHFQQAYGLPDSVLVPGTERSIVNAAAARPVIERRIADADGPGYSRTTEVQLADERWLQINERRTRDGGRVS
VGTDITLMKRHQERLRESERRLMATIGDLSASRQTLEIQKSELSTANANYQAEKERAEAANKAKSEFLANMSHELRTPLN
AILGFSEILQNQMFGPLGSLKYDEYARDIHDSGKHLLNVINDILDMSKIEAGHLRLHCERIDLVPLIEESLRFTAIPAAE
KNIVIDQRISSGLTLTADRRAMKQVLLNLLSNAVKFTDNGGRIAVRTRRIDGAVLVTIADTGIGIPRSALSKIGQPFEQV
QSQYAKSKGGSGLGLAISRSLTALHGGRMKIRSREAVGTVISLRIPDDV

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=250, Percent_Identity=38.8, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1789149, Length=279, Percent_Identity=34.4086021505376, Blast_Score=143, Evalue=5e-35,
Organism=Escherichia coli, GI48994928, Length=245, Percent_Identity=34.6938775510204, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI1788713, Length=246, Percent_Identity=34.1463414634146, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=34.2857142857143, Blast_Score=122, Evalue=9e-29,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=30.2222222222222, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1788393, Length=276, Percent_Identity=26.0869565217391, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788549, Length=319, Percent_Identity=26.3322884012539, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI87082128, Length=246, Percent_Identity=28.0487804878049, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1786912, Length=292, Percent_Identity=27.7397260273973, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=28.125, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1786783, Length=262, Percent_Identity=24.4274809160305, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=249, Percent_Identity=26.1044176706827, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790551, Length=225, Percent_Identity=27.5555555555556, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1788279, Length=212, Percent_Identity=24.5283018867925, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84703; Mature: 84703

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDVRRATVAGGRLRVDFDGLKAWRDSLSGHATSEPLLRHLPKAELLLKRAIPALIVAFL
CCCCCCHHCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
FVVAASHFFGMVSEYSRLEASARHATALSAATASAVFADTSEIFDSGDIAEAQARLARFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHC
PQDRLDSGAFVLLVQASGKVFAATTAGLSHVGSNVGDFFPEVSAIRRFGDRAGVIETTIG
CCCCCCCCCEEEEEECCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHCC
GVPHYAEITLMGNAGGYIVAATSLDEISRLWREQLALNVTLFAGISSILLVILYAYYTQV
CCCCEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRARDADDIFLESNLRVETALSRGRCGLWDFDFENREFFWSRSMYDMLGLPGSDKTMGFG
HHHCCCCCEEEECCCEEEHHHCCCCCCCCCCCCCCCCEEECCCHHHHHCCCCCCCCCCCC
EAARLMHPDDGGLYEIARAIAKGHSGQVDQIFRMRHAGGHYVWMRARAQVIRSNSGRVHL
CHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHCCCCEEEE
IGIAMDVTEQHRLAQRYAEADQRLADAIECTSEAFVLWDKNDRLVMCNTHFQQAYGLPDS
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCHHHHCCCCCC
VLVPGTERSIVNAAAARPVIERRIADADGPGYSRTTEVQLADERWLQINERRTRDGGRVS
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHEEHHHCCCCCCEEE
VGTDITLMKRHQERLRESERRLMATIGDLSASRQTLEIQKSELSTANANYQAEKERAEAA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
NKAKSEFLANMSHELRTPLNAILGFSEILQNQMFGPLGSLKYDEYARDIHDSGKHLLNVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
NDILDMSKIEAGHLRLHCERIDLVPLIEESLRFTAIPAAEKNIVIDQRISSGLTLTADRR
HHHHHHHHCCCCCEEEEEEHCCCHHHHHHCCCEEECCCCCCCEEEEHHHCCCCEEEHHHH
AMKQVLLNLLSNAVKFTDNGGRIAVRTRRIDGAVLVTIADTGIGIPRSALSKIGQPFEQV
HHHHHHHHHHHHHEEEECCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHCCCHHHHH
QSQYAKSKGGSGLGLAISRSLTALHGGRMKIRSREAVGTVISLRIPDDV
HHHHHHCCCCCCEEHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCC
>Mature Secondary Structure
MMDVRRATVAGGRLRVDFDGLKAWRDSLSGHATSEPLLRHLPKAELLLKRAIPALIVAFL
CCCCCCHHCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
FVVAASHFFGMVSEYSRLEASARHATALSAATASAVFADTSEIFDSGDIAEAQARLARFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHC
PQDRLDSGAFVLLVQASGKVFAATTAGLSHVGSNVGDFFPEVSAIRRFGDRAGVIETTIG
CCCCCCCCCEEEEEECCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHCC
GVPHYAEITLMGNAGGYIVAATSLDEISRLWREQLALNVTLFAGISSILLVILYAYYTQV
CCCCEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRARDADDIFLESNLRVETALSRGRCGLWDFDFENREFFWSRSMYDMLGLPGSDKTMGFG
HHHCCCCCEEEECCCEEEHHHCCCCCCCCCCCCCCCCEEECCCHHHHHCCCCCCCCCCCC
EAARLMHPDDGGLYEIARAIAKGHSGQVDQIFRMRHAGGHYVWMRARAQVIRSNSGRVHL
CHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHCCCCEEEE
IGIAMDVTEQHRLAQRYAEADQRLADAIECTSEAFVLWDKNDRLVMCNTHFQQAYGLPDS
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCHHHHCCCCCC
VLVPGTERSIVNAAAARPVIERRIADADGPGYSRTTEVQLADERWLQINERRTRDGGRVS
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHEEHHHCCCCCCEEE
VGTDITLMKRHQERLRESERRLMATIGDLSASRQTLEIQKSELSTANANYQAEKERAEAA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
NKAKSEFLANMSHELRTPLNAILGFSEILQNQMFGPLGSLKYDEYARDIHDSGKHLLNVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
NDILDMSKIEAGHLRLHCERIDLVPLIEESLRFTAIPAAEKNIVIDQRISSGLTLTADRR
HHHHHHHHCCCCCEEEEEEHCCCHHHHHHCCCEEECCCCCCCEEEEHHHCCCCEEEHHHH
AMKQVLLNLLSNAVKFTDNGGRIAVRTRRIDGAVLVTIADTGIGIPRSALSKIGQPFEQV
HHHHHHHHHHHHHEEEECCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHCCCHHHHH
QSQYAKSKGGSGLGLAISRSLTALHGGRMKIRSREAVGTVISLRIPDDV
HHHHHHCCCCCCEEHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]