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The map label for this gene is htrA [H]

Identifier: 209548509

GI number: 209548509

Start: 921773

End: 922678

Strand: Reverse

Name: htrA [H]

Synonym: Rleg2_0906

Alternate gene names: 209548509

Gene position: 922678-921773 (Counterclockwise)

Preceding gene: 209548512

Following gene: 209548507

Centisome position: 20.33

GC content: 62.8

Gene sequence:

>906_bases
ATGAATATCGATCCAATTTTGCGGTCAATCGTGGCCGTTCGTTCTTCCATCCCGGAAGATGCCTTCACAGCGGAGACGTT
GGGCACTGTCCGGGAGGGCAGCGGCGTGGTCATTCGCGACAATGGGCTGGTGCTGACCATCGGTTACCTCATCACCGAGG
CCGAAGAGGTCTGGCTGACCACCCATGACGGGCGCGTCGTTCCCGCCCATGCACTTGCCTATGATCAGGAATCCGGCTTC
GGCCTGGTGCAGGCGCTGGGGGCTCTCAATGCGCCGGCTGTGGATCTCGGCGATGCGGCAAGCGCCAAGGCCGGCGATGC
TGTGGTGCTTGCCGATGGCATCGGAGAATTCGTCGAGGCCAATATCGTCGCCCGGCAGGAATTCGCCGGCTACTGGGAAT
ATCTGCTGGATGAGGCGATTTTCACGGCGCCGGCCCATCCCTCATGGGGTGGTGCGGCGCTGATCGGTTCGGACGGCAAG
CTTCTGGGCATCGGTTCGCTTCGCCTGCAAATGAGCCAGGGCGACGAGGTCGCCGATATCAACATGGTCGTGCCGATCGA
CCTTTTGACTCCGATCCTCGACGATCTGTTGAACCGCGGAAGCGTCAACAAACCGCCGCGGCCCTGGCTCGGCGCATTCT
CCGCCGAGAGCAATGGCGGCGTGGTGGTGATGAGCGTCGCCGAAGGCGGCCCGGCCGCCCAGGCGGGTCTGCGGCAAGGC
GATATCATCTCGGAGATCCGCGATGAAGAGGTCGATGGCCTGGCCGATTTCTACCGCAAGGTCTGGAGCAGCGGCCCGGC
CGGCGCCGAAATTCCGATGCGGATTCTGAGGAACGGCCGGGAAGCCTGGCTGCGCATCAAGTCCGCCGACCGCAACAATT
TTCTCAAGAAGCCGCAGCTGCAGTAA

Upstream 100 bases:

>100_bases
TGGCCATAGCCTTGCCTCCGCCCACCCATCTTCTTACCTATTCAAGACAGAGTGCGTCAGATTTCGGCCTTTCGAGCCGG
CGCTCTGTCAGGATGAAAGC

Downstream 100 bases:

>100_bases
GGTCGCTGACCGCCGCCGAATGCGCTTTCTGTTTGCGCGGACTCTACCGGCGGAGATCTCCGGCGATCCAGCCGATCGCG
GCCTTCACCCGCCGCGGCAC

Product: PDZ/DHR/GLGF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNIDPILRSIVAVRSSIPEDAFTAETLGTVREGSGVVIRDNGLVLTIGYLITEAEEVWLTTHDGRVVPAHALAYDQESGF
GLVQALGALNAPAVDLGDAASAKAGDAVVLADGIGEFVEANIVARQEFAGYWEYLLDEAIFTAPAHPSWGGAALIGSDGK
LLGIGSLRLQMSQGDEVADINMVVPIDLLTPILDDLLNRGSVNKPPRPWLGAFSAESNGGVVVMSVAEGGPAAQAGLRQG
DIISEIRDEEVDGLADFYRKVWSSGPAGAEIPMRILRNGREAWLRIKSADRNNFLKKPQLQ

Sequences:

>Translated_301_residues
MNIDPILRSIVAVRSSIPEDAFTAETLGTVREGSGVVIRDNGLVLTIGYLITEAEEVWLTTHDGRVVPAHALAYDQESGF
GLVQALGALNAPAVDLGDAASAKAGDAVVLADGIGEFVEANIVARQEFAGYWEYLLDEAIFTAPAHPSWGGAALIGSDGK
LLGIGSLRLQMSQGDEVADINMVVPIDLLTPILDDLLNRGSVNKPPRPWLGAFSAESNGGVVVMSVAEGGPAAQAGLRQG
DIISEIRDEEVDGLADFYRKVWSSGPAGAEIPMRILRNGREAWLRIKSADRNNFLKKPQLQ
>Mature_301_residues
MNIDPILRSIVAVRSSIPEDAFTAETLGTVREGSGVVIRDNGLVLTIGYLITEAEEVWLTTHDGRVVPAHALAYDQESGF
GLVQALGALNAPAVDLGDAASAKAGDAVVLADGIGEFVEANIVARQEFAGYWEYLLDEAIFTAPAHPSWGGAALIGSDGK
LLGIGSLRLQMSQGDEVADINMVVPIDLLTPILDDLLNRGSVNKPPRPWLGAFSAESNGGVVVMSVAEGGPAAQAGLRQG
DIISEIRDEEVDGLADFYRKVWSSGPAGAEIPMRILRNGREAWLRIKSADRNNFLKKPQLQ

Specific function: May be involved in processing, maturation, or secretion of extracellular enzymes [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1789629, Length=265, Percent_Identity=26.0377358490566, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786356, Length=269, Percent_Identity=24.5353159851301, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1789630, Length=276, Percent_Identity=26.0869565217391, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 31966; Mature: 31966

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDPILRSIVAVRSSIPEDAFTAETLGTVREGSGVVIRDNGLVLTIGYLITEAEEVWLT
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEHHHHHHCCCEEEEE
THDGRVVPAHALAYDQESGFGLVQALGALNAPAVDLGDAASAKAGDAVVLADGIGEFVEA
ECCCEEEEHHHEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHH
NIVARQEFAGYWEYLLDEAIFTAPAHPSWGGAALIGSDGKLLGIGSLRLQMSQGDEVADI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEEEEECCCCCEEEE
NMVVPIDLLTPILDDLLNRGSVNKPPRPWLGAFSAESNGGVVVMSVAEGGPAAQAGLRQG
EEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHCCCCC
DIISEIRDEEVDGLADFYRKVWSSGPAGAEIPMRILRNGREAWLRIKSADRNNFLKKPQL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHEEEEECCCCCCCCCCCCC
Q
C
>Mature Secondary Structure
MNIDPILRSIVAVRSSIPEDAFTAETLGTVREGSGVVIRDNGLVLTIGYLITEAEEVWLT
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEHHHHHHCCCEEEEE
THDGRVVPAHALAYDQESGFGLVQALGALNAPAVDLGDAASAKAGDAVVLADGIGEFVEA
ECCCEEEEHHHEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHH
NIVARQEFAGYWEYLLDEAIFTAPAHPSWGGAALIGSDGKLLGIGSLRLQMSQGDEVADI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEEEEECCCCCEEEE
NMVVPIDLLTPILDDLLNRGSVNKPPRPWLGAFSAESNGGVVVMSVAEGGPAAQAGLRQG
EEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHCCCCC
DIISEIRDEEVDGLADFYRKVWSSGPAGAEIPMRILRNGREAWLRIKSADRNNFLKKPQL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHEEEEECCCCCCCCCCCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 10692364; 11133960; 11555295 [H]