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The map label for this gene is des [H]

Identifier: 209548501

GI number: 209548501

Start: 914347

End: 915408

Strand: Reverse

Name: des [H]

Synonym: Rleg2_0898

Alternate gene names: 209548501

Gene position: 915408-914347 (Counterclockwise)

Preceding gene: 209548502

Following gene: 209548499

Centisome position: 20.17

GC content: 64.78

Gene sequence:

>1062_bases
GTGGTCCCTTTGGGCGAACCCGCCGCAATCTCGGAGTCCTCCGAGGGGCACAACGCAGTTTTGGCTGAGAAGCGCTGGTT
GAAGATCCTTGCCGGATATCGTCAGCCGAGAGCCGGACGCAGCGCTTTCGAGCTTGCCGTCACGGTCGTCCCCTTCGCGC
TGTTCTGGGCTGCCGCATGGGCTGCGGTTCATTACAGCTTCTGGCCCGGCCTCATCCTCGTCGTTCCCGCCGCCGCCTTC
CTGTTGCGGCTGTTCATGATCCAGCACGATTGCGGCCATGGCTCGTTTTTCGCACGCCGCGGCGTCGACGACTGGGTTGG
ACGAACGATCGGCATCCTGACGCTGACGCCGTACGACTATTGGCGCCGGGCGCATGCCGAGCACCACGCCTCGGCAGGGA
ACCTTGACGAACGCGGCGTCGGCGACATCGAAACGCTGACGATTGCCGAATATAATGCGCTGTCGCGCTGGGGCCGGCTC
GGCTACCGGCTCTACCGGCACCCGGCCGTGATGTTCGGGATCGGGCCGGCATGGCTGTTCATCTTCAAGCAGCGCCTGCC
CTTCGGCATGATGCGCTCCGGCGCCCTGCCCTGGGTCTCCACAATGGCGACCAATCTTGCCATCGCAGCGGTCGCCGCAC
TGCTGATCTGGGCCGTCGGGATCGTCCCCTTCCTGCTGGTGCATCTGCCGACCGTGCTTCTGGCCGGCGCTGCCGGTGTC
TGGCTGTTTTACGTCCAGCACCAGTTCGAGGAAACGCATTGGTCGAAGGAGCCGGACTGGCAGTTCCAGCATGCAGCCCT
CCACGGCGCCTCGCATTACGACCTGCCGCCGGTGCTGCGCTGGATCACCGGCAATATCGGCATCCACCATGTCCATCATC
TGTCGAGCCGGGTGCCCTATTACCGGCTGCCGGAGGTGCTGCGGGACCATCCTGAGCTTGCCGACCTCGGCCGCATCACG
CTCATGGAAAGCCTGCGCTGCGTCAAGCTGGTGTTGTGGGACGAACAGACGAAACGGCTGGTGTCGTTTCGCGATGCGGC
GCGGCTCGCAGCCGCGCAGTAA

Upstream 100 bases:

>100_bases
CGGCTGTGGTGATCGCACTCGGCCTTTCGAGTATCGCGGCCCTTCATGGCGCTATTCTGTGATCGAATCCGCGCGCCGCA
ACGAGAGCAAGGAAATCCAA

Downstream 100 bases:

>100_bases
TCAGCGGCCTCAAAGCGCGTCGCCCCCAATCTGGTTGATGCGGCGCGCTTAGTCCTTTGTTTTTGGCATGTGCCCCCGGG
CGACATGCGTTAGCGGTATC

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MVPLGEPAAISESSEGHNAVLAEKRWLKILAGYRQPRAGRSAFELAVTVVPFALFWAAAWAAVHYSFWPGLILVVPAAAF
LLRLFMIQHDCGHGSFFARRGVDDWVGRTIGILTLTPYDYWRRAHAEHHASAGNLDERGVGDIETLTIAEYNALSRWGRL
GYRLYRHPAVMFGIGPAWLFIFKQRLPFGMMRSGALPWVSTMATNLAIAAVAALLIWAVGIVPFLLVHLPTVLLAGAAGV
WLFYVQHQFEETHWSKEPDWQFQHAALHGASHYDLPPVLRWITGNIGIHHVHHLSSRVPYYRLPEVLRDHPELADLGRIT
LMESLRCVKLVLWDEQTKRLVSFRDAARLAAAQ

Sequences:

>Translated_353_residues
MVPLGEPAAISESSEGHNAVLAEKRWLKILAGYRQPRAGRSAFELAVTVVPFALFWAAAWAAVHYSFWPGLILVVPAAAF
LLRLFMIQHDCGHGSFFARRGVDDWVGRTIGILTLTPYDYWRRAHAEHHASAGNLDERGVGDIETLTIAEYNALSRWGRL
GYRLYRHPAVMFGIGPAWLFIFKQRLPFGMMRSGALPWVSTMATNLAIAAVAALLIWAVGIVPFLLVHLPTVLLAGAAGV
WLFYVQHQFEETHWSKEPDWQFQHAALHGASHYDLPPVLRWITGNIGIHHVHHLSSRVPYYRLPEVLRDHPELADLGRIT
LMESLRCVKLVLWDEQTKRLVSFRDAARLAAAQ
>Mature_353_residues
MVPLGEPAAISESSEGHNAVLAEKRWLKILAGYRQPRAGRSAFELAVTVVPFALFWAAAWAAVHYSFWPGLILVVPAAAF
LLRLFMIQHDCGHGSFFARRGVDDWVGRTIGILTLTPYDYWRRAHAEHHASAGNLDERGVGDIETLTIAEYNALSRWGRL
GYRLYRHPAVMFGIGPAWLFIFKQRLPFGMMRSGALPWVSTMATNLAIAAVAALLIWAVGIVPFLLVHLPTVLLAGAAGV
WLFYVQHQFEETHWSKEPDWQFQHAALHGASHYDLPPVLRWITGNIGIHHVHHLSSRVPYYRLPEVLRDHPELADLGRIT
LMESLRCVKLVLWDEQTKRLVSFRDAARLAAAQ

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 39725; Mature: 39725

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPLGEPAAISESSEGHNAVLAEKRWLKILAGYRQPRAGRSAFELAVTVVPFALFWAAAW
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAVHYSFWPGLILVVPAAAFLLRLFMIQHDCGHGSFFARRGVDDWVGRTIGILTLTPYDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHCCEEEEEEECCHHH
WRRAHAEHHASAGNLDERGVGDIETLTIAEYNALSRWGRLGYRLYRHPAVMFGIGPAWLF
HHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHH
IFKQRLPFGMMRSGALPWVSTMATNLAIAAVAALLIWAVGIVPFLLVHLPTVLLAGAAGV
HHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLFYVQHQFEETHWSKEPDWQFQHAALHGASHYDLPPVLRWITGNIGIHHVHHLSSRVPY
HHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCH
YRLPEVLRDHPELADLGRITLMESLRCVKLVLWDEQTKRLVSFRDAARLAAAQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVPLGEPAAISESSEGHNAVLAEKRWLKILAGYRQPRAGRSAFELAVTVVPFALFWAAAW
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAVHYSFWPGLILVVPAAAFLLRLFMIQHDCGHGSFFARRGVDDWVGRTIGILTLTPYDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHCCEEEEEEECCHHH
WRRAHAEHHASAGNLDERGVGDIETLTIAEYNALSRWGRLGYRLYRHPAVMFGIGPAWLF
HHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHH
IFKQRLPFGMMRSGALPWVSTMATNLAIAAVAALLIWAVGIVPFLLVHLPTVLLAGAAGV
HHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLFYVQHQFEETHWSKEPDWQFQHAALHGASHYDLPPVLRWITGNIGIHHVHHLSSRVPY
HHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCH
YRLPEVLRDHPELADLGRITLMESLRCVKLVLWDEQTKRLVSFRDAARLAAAQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]