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The map label for this gene is msrB [H]

Identifier: 209548475

GI number: 209548475

Start: 891201

End: 891614

Strand: Reverse

Name: msrB [H]

Synonym: Rleg2_0872

Alternate gene names: 209548475

Gene position: 891614-891201 (Counterclockwise)

Preceding gene: 209548485

Following gene: 209548474

Centisome position: 19.65

GC content: 64.01

Gene sequence:

>414_bases
ATGTCCGACACTGCAACCACCGCCAAGATCCACAAGACCGACGCTGAATGGAAAGAGCAGCTCACGCCCGAGCAATACCG
CATCACCCGCCAGCACGGCACCGAGCGCGCCTTCACCGGCCCCTATTGGGATTCCTTCGAGACAGGGCTTTACCGCTGTG
TCGGATGCAACGCCCCGCTTTTTCGCTCCGACACGAAGTTCGATGCCGGCTGCGGCTGGCCGAGCTATTTCGAAGCCGTC
TCGCCCGATGCGGTGACCGAGCATCGCGACACGGCCTTTGGCATGGTGCGCACCGAAATCCGCTGCGGCAGCTGCGAAGC
CCATCTCGGCCACGTCTTCCCAGACGGCCCGCCGCCGACCGGCCTGCGCTACTGCATCAACGGCCATTCCATGGTGTTCG
AGCCGGGGAAGTGA

Upstream 100 bases:

>100_bases
AGCCAATTTCACGGTGCGCTGTTTCAGACTTGATGAACGGACGACGGCGCACCACATTTTCTGGCAAAATGGAACCGCCC
CTCGGCAAAAGGAGCATGGC

Downstream 100 bases:

>100_bases
GCGCCTGGCCCGCAATCGGCAAGCGGCTCATCCCGACGCGATGGGCCGCTGATGGACGGGGGATCCAACGGGCAGGAGAA
GGCCGATGTCGCTAGGTATT

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MSDTATTAKIHKTDAEWKEQLTPEQYRITRQHGTERAFTGPYWDSFETGLYRCVGCNAPLFRSDTKFDAGCGWPSYFEAV
SPDAVTEHRDTAFGMVRTEIRCGSCEAHLGHVFPDGPPPTGLRYCINGHSMVFEPGK

Sequences:

>Translated_137_residues
MSDTATTAKIHKTDAEWKEQLTPEQYRITRQHGTERAFTGPYWDSFETGLYRCVGCNAPLFRSDTKFDAGCGWPSYFEAV
SPDAVTEHRDTAFGMVRTEIRCGSCEAHLGHVFPDGPPPTGLRYCINGHSMVFEPGK
>Mature_136_residues
SDTATTAKIHKTDAEWKEQLTPEQYRITRQHGTERAFTGPYWDSFETGLYRCVGCNAPLFRSDTKFDAGCGWPSYFEAVS
PDAVTEHRDTAFGMVRTEIRCGSCEAHLGHVFPDGPPPTGLRYCINGHSMVFEPGK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=128, Percent_Identity=47.65625, Blast_Score=138, Evalue=1e-33,
Organism=Homo sapiens, GI301336162, Length=128, Percent_Identity=47.65625, Blast_Score=138, Evalue=1e-33,
Organism=Homo sapiens, GI73089054, Length=128, Percent_Identity=47.65625, Blast_Score=138, Evalue=1e-33,
Organism=Homo sapiens, GI37620216, Length=127, Percent_Identity=48.0314960629921, Blast_Score=138, Evalue=2e-33,
Organism=Homo sapiens, GI117606353, Length=141, Percent_Identity=45.3900709219858, Blast_Score=137, Evalue=4e-33,
Organism=Escherichia coli, GI1788077, Length=122, Percent_Identity=52.4590163934426, Blast_Score=144, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17553450, Length=121, Percent_Identity=53.7190082644628, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI115532676, Length=121, Percent_Identity=53.7190082644628, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319816, Length=128, Percent_Identity=42.1875, Blast_Score=115, Evalue=3e-27,
Organism=Drosophila melanogaster, GI221378664, Length=128, Percent_Identity=49.21875, Blast_Score=143, Evalue=3e-35,
Organism=Drosophila melanogaster, GI221378662, Length=135, Percent_Identity=46.6666666666667, Blast_Score=141, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24645799, Length=128, Percent_Identity=47.65625, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI45553335, Length=128, Percent_Identity=47.65625, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21356369, Length=128, Percent_Identity=47.65625, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24645804, Length=139, Percent_Identity=43.8848920863309, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24645801, Length=139, Percent_Identity=43.8848920863309, Blast_Score=133, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15338; Mature: 15207

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTATTAKIHKTDAEWKEQLTPEQYRITRQHGTERAFTGPYWDSFETGLYRCVGCNAPL
CCCCCCCEEEECCCHHHHHCCCCHHEEEHHHCCCCCCCCCCCCCCHHCCCEEEECCCCCC
FRSDTKFDAGCGWPSYFEAVSPDAVTEHRDTAFGMVRTEIRCGSCEAHLGHVFPDGPPPT
CCCCCCCCCCCCCHHHHHHCCCCCHHHCCCCHHHEEEEEEECCCCCCCCCCCCCCCCCCC
GLRYCINGHSMVFEPGK
CEEEEECCCEEEEECCC
>Mature Secondary Structure 
SDTATTAKIHKTDAEWKEQLTPEQYRITRQHGTERAFTGPYWDSFETGLYRCVGCNAPL
CCCCCCEEEECCCHHHHHCCCCHHEEEHHHCCCCCCCCCCCCCCHHCCCEEEECCCCCC
FRSDTKFDAGCGWPSYFEAVSPDAVTEHRDTAFGMVRTEIRCGSCEAHLGHVFPDGPPPT
CCCCCCCCCCCCCHHHHHHCCCCCHHHCCCCHHHEEEEEEECCCCCCCCCCCCCCCCCCC
GLRYCINGHSMVFEPGK
CEEEEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]