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The map label for this gene is ytfL [C]

Identifier: 209548431

GI number: 209548431

Start: 845532

End: 846806

Strand: Reverse

Name: ytfL [C]

Synonym: Rleg2_0828

Alternate gene names: 209548431

Gene position: 846806-845532 (Counterclockwise)

Preceding gene: 209548432

Following gene: 209548430

Centisome position: 18.66

GC content: 57.49

Gene sequence:

>1275_bases
GTGTTTCTGGAAATCGGAATTGTGGCGTTTCTCACCATCGTCAATGGTGTGCTCGCCATGTCGGAGTTGGCTGTTGTGTC
TTCTCGAACAGCCCGCCTAAAAGTTCTCTCCGACCATGGGAGCAAGGGGGCAGCTCAAGCTATTAAACTTGCCGAAAACC
CCGGTCGTTTTCTCTCTACGGTTCAGATCGGCATTACGCTGGTCGGTGTTCTCTCGGGCGCTTTCTCAGGGGCCACCCTC
GGCAGCCGCTTGACCGGATGGCTGGAGACACAGGGGATGTCATCGACGTTAGCCGACGCGATTGGCGTCGGTTCGGTCGT
TGTGGCGATCACCTATCTTTCTTTGATTGTGGGCGAACTTGTTCCGAAGCAGATCGCATTGCGAGAACCCGAAGCCGTTG
CGGCGAAGGTCGCACCGGCCATGGCGGTGCTTTCAAAAATCGCGCTGCCGCTCGTGTGGCTTCTGAACGCCTCCGGAAAT
CTTGTGCTGAAGCTCTTGGGCCAAGCCGGAAAAGGCGGCGACAACGTTTCTGACGAAGAGATCAAAACCGTTCTGGCCGA
GGCGCAGTCGGCCGGCGTTATCGAAAGCGAAGAGTCCGCGATGATATCAGGCGTCATGCGCCTGGCGGACCGCACCGCCC
GAGCGCTTATGACGCCCCGACGCGATGTCGAAATTATCGATATCGACGACAGCCTTGATGAAGTTCGCACTCAATTGCAC
CGGACGAAACGGTCTCGGCTGCCCGTTCGCAAAGGCAGTTCGGACGAGGTGATCGGCATCCTTCCGGTCAAGGATTTTTA
CGACTCGATGTCGGAACACGGCAGTGCCGATATTAAGGCCCTGACGCAGGACGTCCCGGTGGTTTCAGACCTTTCGACCG
CGATCAATGTGATTGAAGCCATCAGGAAATCGCCAGTCCACATGGTGCTGGTTTTTGACGAGTACGGCCATTTCGAGGGG
ATTGTTTCGTCAGGCGACATTCTGGAAGCGATCATGGGGGCTCTGCAGGAGGGACCTGTGGACGAGCAGGCCATCGCGCG
CCGCGACGACGGTTCCTATCTGGTGTCCGGCTGGACGCCGATCGACGAATTCGCCGAGTTCCTGAATCTCAAGCTCGATG
ACGATCTCGAATATCAGACTGTGGCCGGCCTGGTGCTGGAAGAGCTGAAACATCTGCCCGAGTTGGGTGAGAGTTTCACG
CGAGGCGGATGGCGCTTCGAAGTCATCGATCTCGACGGCAGGCGCGTCGACAAGATACTTGTGTCTGCGGAGTGA

Upstream 100 bases:

>100_bases
GACGGAATGACGATGGGTGACGCTGATATAGCGTCGCTTCGAACCCCTCGCCGCGCCGCCTTGTCGATGCGGCATTGAAA
CCTCAACGAATAGGGTCCCT

Downstream 100 bases:

>100_bases
AGCTCGGCGGGGCATACTTGGCTTGAGATCATCGAGCCCGACGGCCGCAACCTGGACGAAATCCGCATCCGCCACATGGA
AAATGTGGCCTGATATCAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MFLEIGIVAFLTIVNGVLAMSELAVVSSRTARLKVLSDHGSKGAAQAIKLAENPGRFLSTVQIGITLVGVLSGAFSGATL
GSRLTGWLETQGMSSTLADAIGVGSVVVAITYLSLIVGELVPKQIALREPEAVAAKVAPAMAVLSKIALPLVWLLNASGN
LVLKLLGQAGKGGDNVSDEEIKTVLAEAQSAGVIESEESAMISGVMRLADRTARALMTPRRDVEIIDIDDSLDEVRTQLH
RTKRSRLPVRKGSSDEVIGILPVKDFYDSMSEHGSADIKALTQDVPVVSDLSTAINVIEAIRKSPVHMVLVFDEYGHFEG
IVSSGDILEAIMGALQEGPVDEQAIARRDDGSYLVSGWTPIDEFAEFLNLKLDDDLEYQTVAGLVLEELKHLPELGESFT
RGGWRFEVIDLDGRRVDKILVSAE

Sequences:

>Translated_424_residues
MFLEIGIVAFLTIVNGVLAMSELAVVSSRTARLKVLSDHGSKGAAQAIKLAENPGRFLSTVQIGITLVGVLSGAFSGATL
GSRLTGWLETQGMSSTLADAIGVGSVVVAITYLSLIVGELVPKQIALREPEAVAAKVAPAMAVLSKIALPLVWLLNASGN
LVLKLLGQAGKGGDNVSDEEIKTVLAEAQSAGVIESEESAMISGVMRLADRTARALMTPRRDVEIIDIDDSLDEVRTQLH
RTKRSRLPVRKGSSDEVIGILPVKDFYDSMSEHGSADIKALTQDVPVVSDLSTAINVIEAIRKSPVHMVLVFDEYGHFEG
IVSSGDILEAIMGALQEGPVDEQAIARRDDGSYLVSGWTPIDEFAEFLNLKLDDDLEYQTVAGLVLEELKHLPELGESFT
RGGWRFEVIDLDGRRVDKILVSAE
>Mature_424_residues
MFLEIGIVAFLTIVNGVLAMSELAVVSSRTARLKVLSDHGSKGAAQAIKLAENPGRFLSTVQIGITLVGVLSGAFSGATL
GSRLTGWLETQGMSSTLADAIGVGSVVVAITYLSLIVGELVPKQIALREPEAVAAKVAPAMAVLSKIALPLVWLLNASGN
LVLKLLGQAGKGGDNVSDEEIKTVLAEAQSAGVIESEESAMISGVMRLADRTARALMTPRRDVEIIDIDDSLDEVRTQLH
RTKRSRLPVRKGSSDEVIGILPVKDFYDSMSEHGSADIKALTQDVPVVSDLSTAINVIEAIRKSPVHMVLVFDEYGHFEG
IVSSGDILEAIMGALQEGPVDEQAIARRDDGSYLVSGWTPIDEFAEFLNLKLDDDLEYQTVAGLVLEELKHLPELGESFT
RGGWRFEVIDLDGRRVDKILVSAE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=371, Percent_Identity=25.6064690026954, Blast_Score=161, Evalue=1e-39,
Organism=Escherichia coli, GI1790664, Length=425, Percent_Identity=27.5294117647059, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI145693175, Length=411, Percent_Identity=28.4671532846715, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI87082033, Length=263, Percent_Identity=29.277566539924, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788119, Length=271, Percent_Identity=30.9963099630996, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786879, Length=271, Percent_Identity=31.3653136531365, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 45382; Mature: 45382

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLEIGIVAFLTIVNGVLAMSELAVVSSRTARLKVLSDHGSKGAAQAIKLAENPGRFLST
CEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHH
VQIGITLVGVLSGAFSGATLGSRLTGWLETQGMSSTLADAIGVGSVVVAITYLSLIVGEL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPKQIALREPEAVAAKVAPAMAVLSKIALPLVWLLNASGNLVLKLLGQAGKGGDNVSDEE
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHH
IKTVLAEAQSAGVIESEESAMISGVMRLADRTARALMTPRRDVEIIDIDDSLDEVRTQLH
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
RTKRSRLPVRKGSSDEVIGILPVKDFYDSMSEHGSADIKALTQDVPVVSDLSTAINVIEA
HHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHH
IRKSPVHMVLVFDEYGHFEGIVSSGDILEAIMGALQEGPVDEQAIARRDDGSYLVSGWTP
HHCCCEEEEEEEECCCCHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEECCCC
IDEFAEFLNLKLDDDLEYQTVAGLVLEELKHLPELGESFTRGGWRFEVIDLDGRRVDKIL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEHEE
VSAE
EECC
>Mature Secondary Structure
MFLEIGIVAFLTIVNGVLAMSELAVVSSRTARLKVLSDHGSKGAAQAIKLAENPGRFLST
CEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHH
VQIGITLVGVLSGAFSGATLGSRLTGWLETQGMSSTLADAIGVGSVVVAITYLSLIVGEL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPKQIALREPEAVAAKVAPAMAVLSKIALPLVWLLNASGNLVLKLLGQAGKGGDNVSDEE
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHH
IKTVLAEAQSAGVIESEESAMISGVMRLADRTARALMTPRRDVEIIDIDDSLDEVRTQLH
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
RTKRSRLPVRKGSSDEVIGILPVKDFYDSMSEHGSADIKALTQDVPVVSDLSTAINVIEA
HHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHH
IRKSPVHMVLVFDEYGHFEGIVSSGDILEAIMGALQEGPVDEQAIARRDDGSYLVSGWTP
HHCCCEEEEEEEECCCCHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEECCCC
IDEFAEFLNLKLDDDLEYQTVAGLVLEELKHLPELGESFTRGGWRFEVIDLDGRRVDKIL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEHEE
VSAE
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]