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The map label for this gene is zwf [H]

Identifier: 209548429

GI number: 209548429

Start: 842856

End: 844373

Strand: Reverse

Name: zwf [H]

Synonym: Rleg2_0826

Alternate gene names: 209548429

Gene position: 844373-842856 (Counterclockwise)

Preceding gene: 209548430

Following gene: 209548426

Centisome position: 18.61

GC content: 63.37

Gene sequence:

>1518_bases
ATGGACGCTGCCCCTACCCCGCCGGTCACCCTCGTCATTTTCGGCGCGACGGGAGACCTGACGCGCCGGCTGCTGGTGCC
GGCGATCATCAACCTGACGCGCGGCCGCCTCGTCGGCGAGGATCTCCACATTCTCGGTATCGGCATCGAGCCGGGCGACG
ACGAATTCCTGCGCAAGCGGCTCGACGAATTCCTCAACCATCTGGGCGGTGATGAACAGGCGCTAAAGGACGAGGCCTGG
GAGAGCCTGCGCCGGCGCATCTCCTATATGGCGGGGGATTTCACCAAGGACGATATTTTCCTCGAAATCGGCAAGCGGCT
GGGACCGGATGCCAATGCCGCTTTCTATCTGGCGGTGCCGCCGTCCTTCTTCGGCTCTATCGTCGAGAAACTCGCCGCCC
ATGGACTGACCGACGAGAAGGACGGCACCTTCCGCCGCGTCGCCATCGAAAAGCCGTTCGGCACCGACCTCGCCTCGGCG
CGAGCGCTGAATGCGCAGATCCTCGCGCAGATCGCAGAAAGCCAAGTCTATCGGCTCGACCATTTCCTCGGCAAGGAGAC
GGTGCAGAACCTGATGACGGCGCGTTTTGCCAATATGATCATCGAGTCTTTGTGGAACAGCCGCTATATCGACCATGTGC
AGATCACCGCCGCCGAGATCGTCGATGTCGGCAGCCGCGGCAAGTTCTACGATGCGACAGGCGCGCTGCGCGACATGGTG
CCGAACCATCTCTTCCAGCTCTTGGCGATGATCGCCATGGAGCCGCCGAACAGCTTCGATGCCGAGGCGATCCGCAACGA
GAAGAGCAAGGTGCTGAAAGCGCTGCGCATCTATACGCCCGAGGAGGCGAAGACGCATGGCGTGCGCGGCGCCTATACCG
CCGGGCCGCTCAACGGTGCCGATCTTCCGGCCTACCGCGACAGCAAGGACGTTTCGCCCGACAGCCGGACCGAGACCTAT
GTGGCGCTGAAGCTCTATGCCGATACCTGGCGCTGGGCCGGCGTGCCCTTCTACCTCAGAACCGGCAAAGCGCTGACGGC
GCGCGACACCGAGATCGTCATCACCTTCCAGCCGGTGCCCTTCGCGCAGTTCCGCGAGACCGAGGTCAATCGCCGCCTGC
CGCCGAACCGGCTGGTGATCCAGGTGCAGCCGGACGAGGGCATGAGCATGGAAATCTCGATCAAGTCGCCGGGGCTCTCG
GTCGAGACCACGCCGGTTTCCCTCGACTTCCGCTATGCCGACAAGTTCGATATCGGCAAGACCACCGGTTATGAATCGCT
GCTCTACGATCTCTTTATCGGCGACCAGACGCTGTTCCAGCGCGCCGACGGCATCGAGGCCGGCTGGGCTGCGGTGCAGC
CCTTCCTGGATATCTGGGGCAAGGATGAGAGTGTGCCCGACGCTTATGCGCCGGGCAGCATGGGGCCGGCCTCAGCCGAC
CAACTCATCGAGCGCGACGGGCGGCGCTGGCATGAACTCGGCGTGATCCTGCAGCAGGACAAGAAAGAGGGCAAATAG

Upstream 100 bases:

>100_bases
ACGCCCCAGATAATGTCAAATGCCTGTTATCCCCCGCCCTCATATGTTGCGGCCAAAGCGGCGCGCATTATAGTCGGCCG
GAAAACTCGGAGATGACATC

Downstream 100 bases:

>100_bases
CGCCCTTCCCTCGTCCTGTCAGTTTCCGCGATCACGGCATGCCGGGCTGAGGGAAGCGCCGCTGTTGCCGCCTTCGGTGG
CAAGGGCGCCGCGGGCCTTG

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MDAAPTPPVTLVIFGATGDLTRRLLVPAIINLTRGRLVGEDLHILGIGIEPGDDEFLRKRLDEFLNHLGGDEQALKDEAW
ESLRRRISYMAGDFTKDDIFLEIGKRLGPDANAAFYLAVPPSFFGSIVEKLAAHGLTDEKDGTFRRVAIEKPFGTDLASA
RALNAQILAQIAESQVYRLDHFLGKETVQNLMTARFANMIIESLWNSRYIDHVQITAAEIVDVGSRGKFYDATGALRDMV
PNHLFQLLAMIAMEPPNSFDAEAIRNEKSKVLKALRIYTPEEAKTHGVRGAYTAGPLNGADLPAYRDSKDVSPDSRTETY
VALKLYADTWRWAGVPFYLRTGKALTARDTEIVITFQPVPFAQFRETEVNRRLPPNRLVIQVQPDEGMSMEISIKSPGLS
VETTPVSLDFRYADKFDIGKTTGYESLLYDLFIGDQTLFQRADGIEAGWAAVQPFLDIWGKDESVPDAYAPGSMGPASAD
QLIERDGRRWHELGVILQQDKKEGK

Sequences:

>Translated_505_residues
MDAAPTPPVTLVIFGATGDLTRRLLVPAIINLTRGRLVGEDLHILGIGIEPGDDEFLRKRLDEFLNHLGGDEQALKDEAW
ESLRRRISYMAGDFTKDDIFLEIGKRLGPDANAAFYLAVPPSFFGSIVEKLAAHGLTDEKDGTFRRVAIEKPFGTDLASA
RALNAQILAQIAESQVYRLDHFLGKETVQNLMTARFANMIIESLWNSRYIDHVQITAAEIVDVGSRGKFYDATGALRDMV
PNHLFQLLAMIAMEPPNSFDAEAIRNEKSKVLKALRIYTPEEAKTHGVRGAYTAGPLNGADLPAYRDSKDVSPDSRTETY
VALKLYADTWRWAGVPFYLRTGKALTARDTEIVITFQPVPFAQFRETEVNRRLPPNRLVIQVQPDEGMSMEISIKSPGLS
VETTPVSLDFRYADKFDIGKTTGYESLLYDLFIGDQTLFQRADGIEAGWAAVQPFLDIWGKDESVPDAYAPGSMGPASAD
QLIERDGRRWHELGVILQQDKKEGK
>Mature_505_residues
MDAAPTPPVTLVIFGATGDLTRRLLVPAIINLTRGRLVGEDLHILGIGIEPGDDEFLRKRLDEFLNHLGGDEQALKDEAW
ESLRRRISYMAGDFTKDDIFLEIGKRLGPDANAAFYLAVPPSFFGSIVEKLAAHGLTDEKDGTFRRVAIEKPFGTDLASA
RALNAQILAQIAESQVYRLDHFLGKETVQNLMTARFANMIIESLWNSRYIDHVQITAAEIVDVGSRGKFYDATGALRDMV
PNHLFQLLAMIAMEPPNSFDAEAIRNEKSKVLKALRIYTPEEAKTHGVRGAYTAGPLNGADLPAYRDSKDVSPDSRTETY
VALKLYADTWRWAGVPFYLRTGKALTARDTEIVITFQPVPFAQFRETEVNRRLPPNRLVIQVQPDEGMSMEISIKSPGLS
VETTPVSLDFRYADKFDIGKTTGYESLLYDLFIGDQTLFQRADGIEAGWAAVQPFLDIWGKDESVPDAYAPGSMGPASAD
QLIERDGRRWHELGVILQQDKKEGK

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=487, Percent_Identity=34.0862422997947, Blast_Score=266, Evalue=4e-71,
Organism=Homo sapiens, GI109389365, Length=487, Percent_Identity=34.0862422997947, Blast_Score=266, Evalue=4e-71,
Organism=Homo sapiens, GI52145310, Length=483, Percent_Identity=26.9151138716356, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1788158, Length=491, Percent_Identity=38.6965376782077, Blast_Score=350, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI17538218, Length=493, Percent_Identity=34.2799188640974, Blast_Score=278, Evalue=4e-75,
Organism=Saccharomyces cerevisiae, GI6324088, Length=493, Percent_Identity=33.4685598377282, Blast_Score=265, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24643350, Length=498, Percent_Identity=35.3413654618474, Blast_Score=266, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24643352, Length=498, Percent_Identity=35.3413654618474, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI221513548, Length=520, Percent_Identity=26.7307692307692, Blast_Score=187, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 56210; Mature: 56210

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAAPTPPVTLVIFGATGDLTRRLLVPAIINLTRGRLVGEDLHILGIGIEPGDDEFLRKR
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEECCCEEEEEEECCCCCHHHHHHH
LDEFLNHLGGDEQALKDEAWESLRRRISYMAGDFTKDDIFLEIGKRLGPDANAAFYLAVP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEEC
PSFFGSIVEKLAAHGLTDEKDGTFRRVAIEKPFGTDLASARALNAQILAQIAESQVYRLD
HHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HFLGKETVQNLMTARFANMIIESLWNSRYIDHVQITAAEIVDVGSRGKFYDATGALRDMV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCCCCCEECHHHHHHHHH
PNHLFQLLAMIAMEPPNSFDAEAIRNEKSKVLKALRIYTPEEAKTHGVRGAYTAGPLNGA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCC
DLPAYRDSKDVSPDSRTETYVALKLYADTWRWAGVPFYLRTGKALTARDTEIVITFQPVP
CCCCCCCCCCCCCCCCCCEEEEEEEEECCHHHCCCCEEEECCCEEEECCCEEEEEECCCC
FAQFRETEVNRRLPPNRLVIQVQPDEGMSMEISIKSPGLSVETTPVSLDFRYADKFDIGK
CHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEECEEEEEEEECCCCCCCC
TTGYESLLYDLFIGDQTLFQRADGIEAGWAAVQPFLDIWGKDESVPDAYAPGSMGPASAD
CCCHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
QLIERDGRRWHELGVILQQDKKEGK
HHHHHCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDAAPTPPVTLVIFGATGDLTRRLLVPAIINLTRGRLVGEDLHILGIGIEPGDDEFLRKR
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEECCCEEEEEEECCCCCHHHHHHH
LDEFLNHLGGDEQALKDEAWESLRRRISYMAGDFTKDDIFLEIGKRLGPDANAAFYLAVP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEEC
PSFFGSIVEKLAAHGLTDEKDGTFRRVAIEKPFGTDLASARALNAQILAQIAESQVYRLD
HHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HFLGKETVQNLMTARFANMIIESLWNSRYIDHVQITAAEIVDVGSRGKFYDATGALRDMV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCCCCCEECHHHHHHHHH
PNHLFQLLAMIAMEPPNSFDAEAIRNEKSKVLKALRIYTPEEAKTHGVRGAYTAGPLNGA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCC
DLPAYRDSKDVSPDSRTETYVALKLYADTWRWAGVPFYLRTGKALTARDTEIVITFQPVP
CCCCCCCCCCCCCCCCCCEEEEEEEEECCHHHCCCCEEEECCCEEEECCCEEEEEECCCC
FAQFRETEVNRRLPPNRLVIQVQPDEGMSMEISIKSPGLSVETTPVSLDFRYADKFDIGK
CHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEECEEEEEEEECCCCCCCC
TTGYESLLYDLFIGDQTLFQRADGIEAGWAAVQPFLDIWGKDESVPDAYAPGSMGPASAD
CCCHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
QLIERDGRRWHELGVILQQDKKEGK
HHHHHCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1643289 [H]