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The map label for this gene is agaR [H]

Identifier: 209548388

GI number: 209548388

Start: 805272

End: 806027

Strand: Reverse

Name: agaR [H]

Synonym: Rleg2_0785

Alternate gene names: 209548388

Gene position: 806027-805272 (Counterclockwise)

Preceding gene: 209548391

Following gene: 209548386

Centisome position: 17.76

GC content: 66.01

Gene sequence:

>756_bases
ATGCTGACGTCCCAACGCAAAACCCTCATCCTCGACATATTGCGCCGTGACGGCCAAGTGATCGCCAAGCGTGTCGCCGA
GGATTTTTCTCTTTCTGAGGACACGATCCGGCGCGACCTCCGCGAAATGGCGGCGGAGGGGCTGTTGAAACGCGTGCATG
GGGGCGCGATGCCGCTGGCGCCGGAACTGCCCGATTTTACCGCGCGGCGCAGCGTTTCGTCGGAGATCAAGGCGCGGCTC
GGGGCTGCTGCGGCGGCGATGGTCAAGCCCGGCCAGATGATCTTTCTCGACGGCGGGACGACGACGGCGGAGATCGCTCG
ACACTTGCCGCGCGACATGCCGCTGACGGTTGCGACCCACAGCCCGACGATCGCCGCCGAACTCGAGCACCACCCGACGG
CGGAGGTGATCCTTGCCGGCGGGCGGCTCTACAAACATTCGATGGTGGCGACGGGCGCGGCGGCGGCGGCGGCGATCTCG
CAGCTGCGCCCCGATCTGTTCTTTCTCGGCGTGACGGCCGCCCATCCCGTGCACGGGCTTTCCACCGGCGATTTCGAGGA
AGCGGCGATCAAACGCCATATCGCCCGCTGCTCGGCCGAAACGCATGTGCTGCTGACGGAGGAGAAGTTCGACCTCGTCT
CGCCCTGCCCGGTGCTTGGAATTTCCGAGGTGGCAGGGCTGATCGTGCCGGCGGAAATGCCGGCCGAGCGGCTGAAACCC
TATCGCGATCTCAACAGCACGATCGCCGTGGCATAG

Upstream 100 bases:

>100_bases
CTTCATGCACGGGATTTCGTGAAAATGCACGATATTCCTTGAATGTCGAGTCTATTCGTGCAATATCGGGCCATTATGTT
TGATTTCGTGCAGAGAGCCC

Downstream 100 bases:

>100_bases
TCATTCGGTCAAGGCGGACGTGACCCTGATATCGCCGACATGGATGCCGTTCCAATTGCGCATCGAGGTTGCGGCAAAGG
CCGTCAGGGCGGCATGCACC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLTSQRKTLILDILRRDGQVIAKRVAEDFSLSEDTIRRDLREMAAEGLLKRVHGGAMPLAPELPDFTARRSVSSEIKARL
GAAAAAMVKPGQMIFLDGGTTTAEIARHLPRDMPLTVATHSPTIAAELEHHPTAEVILAGGRLYKHSMVATGAAAAAAIS
QLRPDLFFLGVTAAHPVHGLSTGDFEEAAIKRHIARCSAETHVLLTEEKFDLVSPCPVLGISEVAGLIVPAEMPAERLKP
YRDLNSTIAVA

Sequences:

>Translated_251_residues
MLTSQRKTLILDILRRDGQVIAKRVAEDFSLSEDTIRRDLREMAAEGLLKRVHGGAMPLAPELPDFTARRSVSSEIKARL
GAAAAAMVKPGQMIFLDGGTTTAEIARHLPRDMPLTVATHSPTIAAELEHHPTAEVILAGGRLYKHSMVATGAAAAAAIS
QLRPDLFFLGVTAAHPVHGLSTGDFEEAAIKRHIARCSAETHVLLTEEKFDLVSPCPVLGISEVAGLIVPAEMPAERLKP
YRDLNSTIAVA
>Mature_251_residues
MLTSQRKTLILDILRRDGQVIAKRVAEDFSLSEDTIRRDLREMAAEGLLKRVHGGAMPLAPELPDFTARRSVSSEIKARL
GAAAAAMVKPGQMIFLDGGTTTAEIARHLPRDMPLTVATHSPTIAAELEHHPTAEVILAGGRLYKHSMVATGAAAAAAIS
QLRPDLFFLGVTAAHPVHGLSTGDFEEAAIKRHIARCSAETHVLLTEEKFDLVSPCPVLGISEVAGLIVPAEMPAERLKP
YRDLNSTIAVA

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=244, Percent_Identity=27.8688524590164, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789829, Length=244, Percent_Identity=29.5081967213115, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI226510968, Length=254, Percent_Identity=30.3149606299213, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787540, Length=236, Percent_Identity=28.8135593220339, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI87082344, Length=235, Percent_Identity=27.2340425531915, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787063, Length=215, Percent_Identity=28.8372093023256, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789170, Length=227, Percent_Identity=25.9911894273128, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789059, Length=240, Percent_Identity=28.75, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790753, Length=243, Percent_Identity=25.5144032921811, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788069, Length=248, Percent_Identity=24.5967741935484, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790635, Length=148, Percent_Identity=27.7027027027027, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26916; Mature: 26916

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSQRKTLILDILRRDGQVIAKRVAEDFSLSEDTIRRDLREMAAEGLLKRVHGGAMPLA
CCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PELPDFTARRSVSSEIKARLGAAAAAMVKPGQMIFLDGGTTTAEIARHLPRDMPLTVATH
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCEEEEEC
SPTIAAELEHHPTAEVILAGGRLYKHSMVATGAAAAAAISQLRPDLFFLGVTAAHPVHGL
CCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCCCCC
STGDFEEAAIKRHIARCSAETHVLLTEEKFDLVSPCPVLGISEVAGLIVPAEMPAERLKP
CCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHEEECCCCCHHHCCH
YRDLNSTIAVA
HHCCCCEEECC
>Mature Secondary Structure
MLTSQRKTLILDILRRDGQVIAKRVAEDFSLSEDTIRRDLREMAAEGLLKRVHGGAMPLA
CCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PELPDFTARRSVSSEIKARLGAAAAAMVKPGQMIFLDGGTTTAEIARHLPRDMPLTVATH
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCEEEEEC
SPTIAAELEHHPTAEVILAGGRLYKHSMVATGAAAAAAISQLRPDLFFLGVTAAHPVHGL
CCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCCCCC
STGDFEEAAIKRHIARCSAETHVLLTEEKFDLVSPCPVLGISEVAGLIVPAEMPAERLKP
CCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHEEECCCCCHHHCCH
YRDLNSTIAVA
HHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]