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The map label for this gene is mas [H]

Identifier: 209548385

GI number: 209548385

Start: 801104

End: 802120

Strand: Direct

Name: mas [H]

Synonym: Rleg2_0782

Alternate gene names: 209548385

Gene position: 801104-802120 (Clockwise)

Preceding gene: 209548384

Following gene: 209548387

Centisome position: 17.65

GC content: 64.31

Gene sequence:

>1017_bases
ATGTCACTGCCTCATGAAATGTCACTGCCTCAGGAAATGCGTTTCGTCGATCTGCCGTCTTTCGGCGGGCCGGAAGTGAT
GACCATCGGCAGACGCCCGCTTCCGGTGCCGGGTGAGGGACAGGTCCTCGTCCGCGCCGAGGCGATCGGCGTCAACCGCC
CCGATGTCGCCCAGCGCCAGGGCAGCTATCCCGCGCCCAGGGATGCGAGCCCGATCCTCGGCCTGGAACTGTCGGGCGAA
ATCGTTGCGATTGGCCTTGGCGTCAGCGGCTACCGCGTCGGCGACAAGGTCTGCGGGCTCGCCAATGGCGGCGCCTATGC
CGAATATTGCCTGCTGCCGGCCGGCCAGATTCTACCCTTTCCCAAGGGCTATGACGCGGTGAAGGCCGCGGCCCTTCCCG
AAACCTTCTTCACCGTCTGGGCCAATCTCTTCCAGATGGCCGGGCTGACCGAAGGCGAGACCGTGCTGATCCATGGCGGC
TCCAGCGGCATCGGCACGACGGCGATCCAGCTCGCCCGTGCCTTCGGCGCCGAGGTCTACGCCACGGCCGGTTCAAGCGA
GAAATGCGCGGCCTGCGAAAGGCTCGGCGCCAAACGCGCGATCAACTACAAAAGCGAGGATTTCGCCGAGGTGATCAAGG
CCGAGACCGGCCAGGGCGTCGATATCATTCTCGACATGATCGGCGCCGCCTATTTCGAGCGCAACCTCGCCTCGCTTGGA
AAAGACGGCTGCCTGTCGATCATCGCCTTCCTCGGCGGCGCCATTGCCGAAAAGGTCAATCTGTCGCCGATCATGGTCAA
GCGCCTGACGGTCACCGGCTCCACCATGCGCCCGCGCACGGCCGAGGAAAAACGTGCCATTCGCGATGATCTGCTCTCCG
AGGTCTGGCCGCTTTTGGAAGCCGGCACCGTCGCCCCCGTCATCCACAAGGTCTTCGCCTTTGAAGAGGTCGTGGCCGCC
CATCGGCTGATGGAAGACGGCAGCCACGTCGGCAAGATCATGCTCAGCGTCGGCTAA

Upstream 100 bases:

>100_bases
CGGGGCTGACTTATTTCCTTGGCGCAGAGCATTTCCAGCAAAAGTGTGTCGCGGTTTTGCGTCCGGAATGCCCGAAAGAT
GCGTCAGGGAGGGCCGCGCC

Downstream 100 bases:

>100_bases
GTGACAGTGACACGCCGATGGCGAAAACGCCGGGTAGCGCCATCAGCAGATAGAGCCAATAGGCTGCCGACAGCGCCCCG
GATATGCCGCCCGGATCGAC

Product: NAD(P)H quinone oxidoreductase, PIG3 family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSLPHEMSLPQEMRFVDLPSFGGPEVMTIGRRPLPVPGEGQVLVRAEAIGVNRPDVAQRQGSYPAPRDASPILGLELSGE
IVAIGLGVSGYRVGDKVCGLANGGAYAEYCLLPAGQILPFPKGYDAVKAAALPETFFTVWANLFQMAGLTEGETVLIHGG
SSGIGTTAIQLARAFGAEVYATAGSSEKCAACERLGAKRAINYKSEDFAEVIKAETGQGVDIILDMIGAAYFERNLASLG
KDGCLSIIAFLGGAIAEKVNLSPIMVKRLTVTGSTMRPRTAEEKRAIRDDLLSEVWPLLEAGTVAPVIHKVFAFEEVVAA
HRLMEDGSHVGKIMLSVG

Sequences:

>Translated_338_residues
MSLPHEMSLPQEMRFVDLPSFGGPEVMTIGRRPLPVPGEGQVLVRAEAIGVNRPDVAQRQGSYPAPRDASPILGLELSGE
IVAIGLGVSGYRVGDKVCGLANGGAYAEYCLLPAGQILPFPKGYDAVKAAALPETFFTVWANLFQMAGLTEGETVLIHGG
SSGIGTTAIQLARAFGAEVYATAGSSEKCAACERLGAKRAINYKSEDFAEVIKAETGQGVDIILDMIGAAYFERNLASLG
KDGCLSIIAFLGGAIAEKVNLSPIMVKRLTVTGSTMRPRTAEEKRAIRDDLLSEVWPLLEAGTVAPVIHKVFAFEEVVAA
HRLMEDGSHVGKIMLSVG
>Mature_337_residues
SLPHEMSLPQEMRFVDLPSFGGPEVMTIGRRPLPVPGEGQVLVRAEAIGVNRPDVAQRQGSYPAPRDASPILGLELSGEI
VAIGLGVSGYRVGDKVCGLANGGAYAEYCLLPAGQILPFPKGYDAVKAAALPETFFTVWANLFQMAGLTEGETVLIHGGS
SGIGTTAIQLARAFGAEVYATAGSSEKCAACERLGAKRAINYKSEDFAEVIKAETGQGVDIILDMIGAAYFERNLASLGK
DGCLSIIAFLGGAIAEKVNLSPIMVKRLTVTGSTMRPRTAEEKRAIRDDLLSEVWPLLEAGTVAPVIHKVFAFEEVVAAH
RLMEDGSHVGKIMLSVG

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=37.2727272727273, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=37.2727272727273, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI194239674, Length=331, Percent_Identity=31.1178247734139, Blast_Score=144, Evalue=8e-35,
Organism=Homo sapiens, GI13236495, Length=331, Percent_Identity=31.1178247734139, Blast_Score=144, Evalue=8e-35,
Organism=Homo sapiens, GI24308257, Length=351, Percent_Identity=28.2051282051282, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI28557745, Length=355, Percent_Identity=30.7042253521127, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI194239676, Length=330, Percent_Identity=29.0909090909091, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI18379349, Length=348, Percent_Identity=28.448275862069, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI41872631, Length=275, Percent_Identity=27.6363636363636, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI47519420, Length=335, Percent_Identity=25.9701492537313, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI197927207, Length=196, Percent_Identity=30.1020408163265, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=28.7461773700306, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI226510941, Length=269, Percent_Identity=24.1635687732342, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788073, Length=238, Percent_Identity=28.1512605042017, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=326, Percent_Identity=25.7668711656442, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI212642053, Length=286, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71988145, Length=202, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=343, Percent_Identity=27.4052478134111, Blast_Score=115, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6323961, Length=312, Percent_Identity=25, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=312, Percent_Identity=24.6794871794872, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319621, Length=284, Percent_Identity=25.3521126760563, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581345, Length=277, Percent_Identity=27.4368231046931, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221330659, Length=275, Percent_Identity=26.1818181818182, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI19920632, Length=275, Percent_Identity=26.1818181818182, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI45550423, Length=294, Percent_Identity=25.1700680272109, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 35729; Mature: 35597

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPHEMSLPQEMRFVDLPSFGGPEVMTIGRRPLPVPGEGQVLVRAEAIGVNRPDVAQRQ
CCCCCCCCCCHHCCEEECCCCCCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCHHHHC
GSYPAPRDASPILGLELSGEIVAIGLGVSGYRVGDKVCGLANGGAYAEYCLLPAGQILPF
CCCCCCCCCCCEEEEEECCCEEEEEECCCCEECCHHHHCCCCCCCHHHHHCCCCCCCCCC
PKGYDAVKAAALPETFFTVWANLFQMAGLTEGETVLIHGGSSGIGTTAIQLARAFGAEVY
CCCCHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEE
ATAGSSEKCAACERLGAKRAINYKSEDFAEVIKAETGQGVDIILDMIGAAYFERNLASLG
EECCCCHHHHHHHHHCHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
KDGCLSIIAFLGGAIAEKVNLSPIMVKRLTVTGSTMRPRTAEEKRAIRDDLLSEVWPLLE
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AGTVAPVIHKVFAFEEVVAAHRLMEDGSHVGKIMLSVG
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure 
SLPHEMSLPQEMRFVDLPSFGGPEVMTIGRRPLPVPGEGQVLVRAEAIGVNRPDVAQRQ
CCCCCCCCCHHCCEEECCCCCCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCHHHHC
GSYPAPRDASPILGLELSGEIVAIGLGVSGYRVGDKVCGLANGGAYAEYCLLPAGQILPF
CCCCCCCCCCCEEEEEECCCEEEEEECCCCEECCHHHHCCCCCCCHHHHHCCCCCCCCCC
PKGYDAVKAAALPETFFTVWANLFQMAGLTEGETVLIHGGSSGIGTTAIQLARAFGAEVY
CCCCHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEE
ATAGSSEKCAACERLGAKRAINYKSEDFAEVIKAETGQGVDIILDMIGAAYFERNLASLG
EECCCCHHHHHHHHHCHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
KDGCLSIIAFLGGAIAEKVNLSPIMVKRLTVTGSTMRPRTAEEKRAIRDDLLSEVWPLLE
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AGTVAPVIHKVFAFEEVVAAHRLMEDGSHVGKIMLSVG
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]