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The map label for this gene is tldD [H]

Identifier: 209548205

GI number: 209548205

Start: 624603

End: 626018

Strand: Reverse

Name: tldD [H]

Synonym: Rleg2_0599

Alternate gene names: 209548205

Gene position: 626018-624603 (Counterclockwise)

Preceding gene: 209548207

Following gene: 209548204

Centisome position: 13.8

GC content: 64.9

Gene sequence:

>1416_bases
ATGACCACCGATCTCCTGACGCTATTCGATGCCGATGAAGCCACGATGCGTGGTCTGGTTGCCGAGGCGCTCGCCGGCGC
CGATGACGGTGAGCTGTTCATCGAGCATGCGCAGGCCGAAGCGCTGACCTTCGACAATGGCCGGCTGAAGGGCGGCAGCT
TCAACACCGAACAGGGATTCGGCCTGCGTGCCGTTGCCGGCGAAGCGGTGGGCTACGCCCATGCCGGCGACCTCTCGGTG
GCGGCGCTGAAGCGCGCGGCGGATGCGGTGGGCGCAGTGACGCGCGGCTATTCCGGCTCCTATGCGGCCGCCCCGCAAGG
CACCAACAAGAAATTCTACGGCGACCAGAACCCGATCGGCCAGCCAAGCTTTGAGGAAAAGGTCAAGGTCCTGCAGGATA
TCGACGCCTATCTGAGGGGCAAGAACGACAAGGTGCGGCAGGTGACAGCCTCGGTGGCGGCGAGCTGGCAGGTCGTCGAC
ATCCTGCGCGCCGACGGGCATCGCGTGCGCGACATCAGGCCGATGACCCGCATCAACATCTCGGTCATGGTCGGCGAAGG
CGATCGCCAGGAAAGCGGCTCCTACGGCAGCGGCGGACGCATCGGTTTCGGCGATTTCATCGCCGAGGGCAGCTGGCAAT
ATGGCGCCGACGAGGCGCTGCGCCAGGCGCTCGTCAACCTTGAAGCAATCGATGCGCCGGCGGGCACGATGGACGTCGTT
CTCGGCTCCGGCTGGCCGGGCGTGATGCTGCACGAAGCCGTCGGCCACGGGCTGGAAGGCGATTTCAACCGCAAGAAGAC
GTCGGCCTTTGCGGGCCTGCTCGGCCAGATGGTCGCCGCTCCCGGCGTGACCGTCGTCGACGACGGCACGATCGACAATC
GCCGTGGTTCGATCACCATCGACGACGAGGGCACGCCGTCGGGCTACAACGTGCTGATCGAGAACGGCAAGCTCGTCGGC
TATATGCAGGATCGGCAGAATGCCCGGCTGATGGGCATGCAGCCCACCGGCAACGGCCGCCGCCAGGGTTATGCGCATGT
GCCGATGCCACGCATGACCAACACCTATATGCTCGGCGGCGACAAGACGCCCGAGGAAATCATCGCCTCGGTGAAGAAGG
GCATCTATGCCGTTTCCTTCGGCGGCGGCCAGGTGGATATCACCTCCGGCAAGTTCGTCTTCGGCTGCACCGAGGCCTAT
CTGATCGAGAACGGCAAGGTCGGCGCACCGATCAAGGGTGCGATGCTGATCGGCAACGGCCCGGATGCGATGAAGCGGGT
GTCGATGATCGGCAACGACATGAAGCTCGATACCGGCATCGGCAATTGCGGCAAGGGCGGCCAATGGGTTCCGGTCGGCG
TCGGCCAGCCGCATCTGCGCATGGATCAGATCACCGTCGGCGGCACCCAGACCTAA

Upstream 100 bases:

>100_bases
AGCAAAGAATAATTCGAGGCGGGGCTTCACTCGGCATGAGGTTGAGCCCTATCTAGGGAAGTAAGCGCATTCCCGAACGC
ATGCCCATTGGAGCCATACC

Downstream 100 bases:

>100_bases
GACGAAAGGAGCCTGTCATGGCGGAGGTCGAGATCAGGCGTTTTGCGGAAGGCGACGCCGATGACGTGCTTTCGGTGATC
CTGCCGATCCAGCGCGAAGA

Product: peptidase U62 modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MTTDLLTLFDADEATMRGLVAEALAGADDGELFIEHAQAEALTFDNGRLKGGSFNTEQGFGLRAVAGEAVGYAHAGDLSV
AALKRAADAVGAVTRGYSGSYAAAPQGTNKKFYGDQNPIGQPSFEEKVKVLQDIDAYLRGKNDKVRQVTASVAASWQVVD
ILRADGHRVRDIRPMTRINISVMVGEGDRQESGSYGSGGRIGFGDFIAEGSWQYGADEALRQALVNLEAIDAPAGTMDVV
LGSGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQMVAAPGVTVVDDGTIDNRRGSITIDDEGTPSGYNVLIENGKLVG
YMQDRQNARLMGMQPTGNGRRQGYAHVPMPRMTNTYMLGGDKTPEEIIASVKKGIYAVSFGGGQVDITSGKFVFGCTEAY
LIENGKVGAPIKGAMLIGNGPDAMKRVSMIGNDMKLDTGIGNCGKGGQWVPVGVGQPHLRMDQITVGGTQT

Sequences:

>Translated_471_residues
MTTDLLTLFDADEATMRGLVAEALAGADDGELFIEHAQAEALTFDNGRLKGGSFNTEQGFGLRAVAGEAVGYAHAGDLSV
AALKRAADAVGAVTRGYSGSYAAAPQGTNKKFYGDQNPIGQPSFEEKVKVLQDIDAYLRGKNDKVRQVTASVAASWQVVD
ILRADGHRVRDIRPMTRINISVMVGEGDRQESGSYGSGGRIGFGDFIAEGSWQYGADEALRQALVNLEAIDAPAGTMDVV
LGSGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQMVAAPGVTVVDDGTIDNRRGSITIDDEGTPSGYNVLIENGKLVG
YMQDRQNARLMGMQPTGNGRRQGYAHVPMPRMTNTYMLGGDKTPEEIIASVKKGIYAVSFGGGQVDITSGKFVFGCTEAY
LIENGKVGAPIKGAMLIGNGPDAMKRVSMIGNDMKLDTGIGNCGKGGQWVPVGVGQPHLRMDQITVGGTQT
>Mature_470_residues
TTDLLTLFDADEATMRGLVAEALAGADDGELFIEHAQAEALTFDNGRLKGGSFNTEQGFGLRAVAGEAVGYAHAGDLSVA
ALKRAADAVGAVTRGYSGSYAAAPQGTNKKFYGDQNPIGQPSFEEKVKVLQDIDAYLRGKNDKVRQVTASVAASWQVVDI
LRADGHRVRDIRPMTRINISVMVGEGDRQESGSYGSGGRIGFGDFIAEGSWQYGADEALRQALVNLEAIDAPAGTMDVVL
GSGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQMVAAPGVTVVDDGTIDNRRGSITIDDEGTPSGYNVLIENGKLVGY
MQDRQNARLMGMQPTGNGRRQGYAHVPMPRMTNTYMLGGDKTPEEIIASVKKGIYAVSFGGGQVDITSGKFVFGCTEAYL
IENGKVGAPIKGAMLIGNGPDAMKRVSMIGNDMKLDTGIGNCGKGGQWVPVGVGQPHLRMDQITVGGTQT

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=448, Percent_Identity=54.2410714285714, Blast_Score=471, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 49646; Mature: 49514

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDLLTLFDADEATMRGLVAEALAGADDGELFIEHAQAEALTFDNGRLKGGSFNTEQGF
CCCCEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCCEECCCCCCCCCCC
GLRAVAGEAVGYAHAGDLSVAALKRAADAVGAVTRGYSGSYAAAPQGTNKKFYGDQNPIG
CEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
QPSFEEKVKVLQDIDAYLRGKNDKVRQVTASVAASWQVVDILRADGHRVRDIRPMTRINI
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEEECCCCCEEECCCCEEEEEE
SVMVGEGDRQESGSYGSGGRIGFGDFIAEGSWQYGADEALRQALVNLEAIDAPAGTMDVV
EEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCCCEEEE
LGSGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQMVAAPGVTVVDDGTIDNRRGSITI
EECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEE
DDEGTPSGYNVLIENGKLVGYMQDRQNARLMGMQPTGNGRRQGYAHVPMPRMTNTYMLGG
CCCCCCCCCEEEEECCEEEEEEECCCCCEEEEECCCCCCCCCCEEECCCCCCCCEEEECC
DKTPEEIIASVKKGIYAVSFGGGQVDITSGKFVFGCTEAYLIENGKVGAPIKGAMLIGNG
CCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEECCEEEEEECCCCCCCCCCEEEECCC
PDAMKRVSMIGNDMKLDTGIGNCGKGGQWVPVGVGQPHLRMDQITVGGTQT
HHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
TTDLLTLFDADEATMRGLVAEALAGADDGELFIEHAQAEALTFDNGRLKGGSFNTEQGF
CCCEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCCEECCCCCCCCCCC
GLRAVAGEAVGYAHAGDLSVAALKRAADAVGAVTRGYSGSYAAAPQGTNKKFYGDQNPIG
CEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
QPSFEEKVKVLQDIDAYLRGKNDKVRQVTASVAASWQVVDILRADGHRVRDIRPMTRINI
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEEECCCCCEEECCCCEEEEEE
SVMVGEGDRQESGSYGSGGRIGFGDFIAEGSWQYGADEALRQALVNLEAIDAPAGTMDVV
EEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCCCEEEE
LGSGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQMVAAPGVTVVDDGTIDNRRGSITI
EECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEE
DDEGTPSGYNVLIENGKLVGYMQDRQNARLMGMQPTGNGRRQGYAHVPMPRMTNTYMLGG
CCCCCCCCCEEEEECCEEEEEEECCCCCEEEEECCCCCCCCCCEEECCCCCCCCEEEECC
DKTPEEIIASVKKGIYAVSFGGGQVDITSGKFVFGCTEAYLIENGKVGAPIKGAMLIGNG
CCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEECCEEEEEECCCCCCCCCCEEEECCC
PDAMKRVSMIGNDMKLDTGIGNCGKGGQWVPVGVGQPHLRMDQITVGGTQT
HHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]