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The map label for this gene is ectC [H]

Identifier: 209548184

GI number: 209548184

Start: 603142

End: 603528

Strand: Reverse

Name: ectC [H]

Synonym: Rleg2_0578

Alternate gene names: 209548184

Gene position: 603528-603142 (Counterclockwise)

Preceding gene: 209548187

Following gene: 209548183

Centisome position: 13.3

GC content: 56.85

Gene sequence:

>387_bases
ATGTTTGTGAGAAGTCTAAAGGAAGTCGAGCAGACCGAGCGCTTCGTCGATTGGGGCAATGGCACGAGCCATCGCCTGCT
GACCAATGATGACGGGATGGGGTTCACGGTCTGCCACACGGTCGTTCGCGCCAACACGCAAGCCCTGCTGCAGTACCGCA
ACCACCTGGAAGCCTGCTACTGCATCCAGGGAGAAGGCGAGGTCGAGGATATGGACGGCAACGTCTTCCCCATCGGCGTC
GGCGACATCTACGTCCTCGATAAACATGATCGCCACTATTTGCGGGGCGGCAAGGACAGGGACCTCATTCTCGTCAGCAT
CTTCAATCCACCTCTGAAAGGGACGGAACGTCACGATCTGAACAACAGAAGCGGTTCCGAATACTGA

Upstream 100 bases:

>100_bases
AACTTCCTCAATTTTGATCATTTGAAGCAAGTGTGGATTCCGGTGCCTATTGGGATCACGGAGATCAAAGACATCTCCGT
CATTTGCGAGAGGAAAGAAC

Downstream 100 bases:

>100_bases
GGCCCAGCGACGCGGCGGGGGTGCTGCAATCTTCCTGAGCGGCTCACGATCTTCATCAGCTGCCGATCTCCGGCCGGGTC
GCCCGTCCTTGGCGAACAGT

Product: L-ectoine synthase

Products: NA

Alternate protein names: N-acetyldiaminobutyrate dehydratase [H]

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MFVRSLKEVEQTERFVDWGNGTSHRLLTNDDGMGFTVCHTVVRANTQALLQYRNHLEACYCIQGEGEVEDMDGNVFPIGV
GDIYVLDKHDRHYLRGGKDRDLILVSIFNPPLKGTERHDLNNRSGSEY

Sequences:

>Translated_128_residues
MFVRSLKEVEQTERFVDWGNGTSHRLLTNDDGMGFTVCHTVVRANTQALLQYRNHLEACYCIQGEGEVEDMDGNVFPIGV
GDIYVLDKHDRHYLRGGKDRDLILVSIFNPPLKGTERHDLNNRSGSEY
>Mature_128_residues
MFVRSLKEVEQTERFVDWGNGTSHRLLTNDDGMGFTVCHTVVRANTQALLQYRNHLEACYCIQGEGEVEDMDGNVFPIGV
GDIYVLDKHDRHYLRGGKDRDLILVSIFNPPLKGTERHDLNNRSGSEY

Specific function: Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ectoine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR010462
- InterPro:   IPR014710
- ProDom:   PD080544 [H]

Pfam domain/function: PF06339 Ectoine_synth [H]

EC number: =4.2.1.108 [H]

Molecular weight: Translated: 14614; Mature: 14614

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVRSLKEVEQTERFVDWGNGTSHRLLTNDDGMGFTVCHTVVRANTQALLQYRNHLEACY
CCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCEEE
CIQGEGEVEDMDGNVFPIGVGDIYVLDKHDRHYLRGGKDRDLILVSIFNPPLKGTERHDL
EECCCCCEECCCCCEEEEECCEEEEEECCCCHHHCCCCCCCEEEEEEECCCCCCCCCCCC
NNRSGSEY
CCCCCCCC
>Mature Secondary Structure
MFVRSLKEVEQTERFVDWGNGTSHRLLTNDDGMGFTVCHTVVRANTQALLQYRNHLEACY
CCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCEEE
CIQGEGEVEDMDGNVFPIGVGDIYVLDKHDRHYLRGGKDRDLILVSIFNPPLKGTERHDL
EECCCCCEECCCCCEEEEECCEEEEEECCCCHHHCCCCCCCEEEEEEECCCCCCCCCCCC
NNRSGSEY
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]