Click here to switch to the map view.

The map label for this gene is 209548176

Identifier: 209548176

GI number: 209548176

Start: 594200

End: 595135

Strand: Reverse

Name: 209548176

Synonym: Rleg2_0570

Alternate gene names: NA

Gene position: 595135-594200 (Counterclockwise)

Preceding gene: 209548178

Following gene: 209548175

Centisome position: 13.11

GC content: 63.57

Gene sequence:

>936_bases
ATGAGCACCCGTCTTTATGAGCATCCGATCTTCCTGGAACATGTCACGCCCGCCGGTCATCCGGAGCGATCGGACAGAAT
CCGCGCCATCAATGTCGCACTCGAACATCCGAATTTCGAGCGGCTGGAGCGCCGGCAGGCGCCTGAAGCAAGCGAGGATG
CGGTGCTGCTGGCCCATCCGGAAGAGCATCTGACAGCCGTCATGCGGGAGATCCCCGACGAAGAAGACCGCATCAACCAG
CTCGAAGCCGATACCTATGCCAGCCAAAAGAGCCTGCAGGCGGCGCTGACCGGCATCGGCGGGGCGATGGCGGCGGTGGA
CGACGTCTTCTCAGGCGCCGCCGACAATGTCTTCGTCGCCGCCCGCCCGCCCGGCCACCATGCCGAGAAGATGACGGCGA
TGGGCTTCTGCTTCTTCAACAATGCGGCGATCGCCGCCCGCCATGCGCAGAAGCGGCATGGCGCCGAGCGCGTCGCCATC
ATCGACTGGGACGTGCATCACGGCAACGGCACCCAGGATATCTTCTGGGACGACCCCTCGGTGCTGTTCTGCTCGACGCA
TCAGATGCCGCTTTATCCCGGCAGCGGCGCCAAGGACGAGAAGGGCAAACACAACACCATCGTCAATGCGCCGCTTTCGC
CGAATGTCGGCAGCGACCATTTCCGCGAGGCGTTCAAATCGCGCGTGCTGCCGGCCGTCGCCGATTTCCGGCCGGATCTC
ATCATCATCTCCGCCGGCTTCGACGCCCATCACCGCGATCCCTTAGCGCAGATCAACCTGACGGGCGAGGATTTCGACTG
GGCGACCGGCCGCGTGCTCGAACTAGCCGACCGGCACGCGAAGAACCGGGTCGTCAGCCTGCTCGAAGGCGGTTATGATC
TCGAGGGGCTCGCCGAATCGGCGGGCATGCATATTCTGCGAATGATGAAGGGTTGA

Upstream 100 bases:

>100_bases
CCGGCGGCGGCGAGATGGGGCGCAGGCGCGCTTGTTGAAATCGTCGGGCGATGCCCCATCTGCTGTGGAACATGACATAA
GCGACCGATAGAGTGTCTCC

Downstream 100 bases:

>100_bases
GAATGACTGACAGCGCCAAGCCGGAGGTATCCGGCCTTTCCTTCGAAAAGGCGGTCGCCGAACTCGAAAGCATCGTCGCC
CGGCTGGAACGCGGCGACGT

Product: histone deacetylase superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSTRLYEHPIFLEHVTPAGHPERSDRIRAINVALEHPNFERLERRQAPEASEDAVLLAHPEEHLTAVMREIPDEEDRINQ
LEADTYASQKSLQAALTGIGGAMAAVDDVFSGAADNVFVAARPPGHHAEKMTAMGFCFFNNAAIAARHAQKRHGAERVAI
IDWDVHHGNGTQDIFWDDPSVLFCSTHQMPLYPGSGAKDEKGKHNTIVNAPLSPNVGSDHFREAFKSRVLPAVADFRPDL
IIISAGFDAHHRDPLAQINLTGEDFDWATGRVLELADRHAKNRVVSLLEGGYDLEGLAESAGMHILRMMKG

Sequences:

>Translated_311_residues
MSTRLYEHPIFLEHVTPAGHPERSDRIRAINVALEHPNFERLERRQAPEASEDAVLLAHPEEHLTAVMREIPDEEDRINQ
LEADTYASQKSLQAALTGIGGAMAAVDDVFSGAADNVFVAARPPGHHAEKMTAMGFCFFNNAAIAARHAQKRHGAERVAI
IDWDVHHGNGTQDIFWDDPSVLFCSTHQMPLYPGSGAKDEKGKHNTIVNAPLSPNVGSDHFREAFKSRVLPAVADFRPDL
IIISAGFDAHHRDPLAQINLTGEDFDWATGRVLELADRHAKNRVVSLLEGGYDLEGLAESAGMHILRMMKG
>Mature_310_residues
STRLYEHPIFLEHVTPAGHPERSDRIRAINVALEHPNFERLERRQAPEASEDAVLLAHPEEHLTAVMREIPDEEDRINQL
EADTYASQKSLQAALTGIGGAMAAVDDVFSGAADNVFVAARPPGHHAEKMTAMGFCFFNNAAIAARHAQKRHGAERVAII
DWDVHHGNGTQDIFWDDPSVLFCSTHQMPLYPGSGAKDEKGKHNTIVNAPLSPNVGSDHFREAFKSRVLPAVADFRPDLI
IISAGFDAHHRDPLAQINLTGEDFDWATGRVLELADRHAKNRVVSLLEGGYDLEGLAESAGMHILRMMKG

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI153085395, Length=337, Percent_Identity=33.2344213649852, Blast_Score=174, Evalue=8e-44,
Organism=Homo sapiens, GI17158039, Length=332, Percent_Identity=34.0361445783133, Blast_Score=173, Evalue=1e-43,
Organism=Homo sapiens, GI30795202, Length=332, Percent_Identity=34.0361445783133, Blast_Score=173, Evalue=1e-43,
Organism=Homo sapiens, GI30795204, Length=332, Percent_Identity=34.0361445783133, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI20070354, Length=302, Percent_Identity=36.7549668874172, Blast_Score=171, Evalue=6e-43,
Organism=Homo sapiens, GI13128864, Length=295, Percent_Identity=37.6271186440678, Blast_Score=167, Evalue=8e-42,
Organism=Homo sapiens, GI169234807, Length=339, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI148539870, Length=339, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI62750347, Length=316, Percent_Identity=33.5443037974684, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI62750349, Length=316, Percent_Identity=33.5443037974684, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI226529806, Length=302, Percent_Identity=33.4437086092715, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI13128860, Length=258, Percent_Identity=27.1317829457364, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI293336691, Length=258, Percent_Identity=26.7441860465116, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI8923769, Length=247, Percent_Identity=25.9109311740891, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI13128862, Length=268, Percent_Identity=24.2537313432836, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI262073088, Length=181, Percent_Identity=24.8618784530387, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI217272877, Length=260, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17540334, Length=300, Percent_Identity=37.3333333333333, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI193206283, Length=300, Percent_Identity=37.3333333333333, Blast_Score=185, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17540332, Length=300, Percent_Identity=37.3333333333333, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI193209491, Length=315, Percent_Identity=38.0952380952381, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI25154020, Length=281, Percent_Identity=28.4697508896797, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25154022, Length=281, Percent_Identity=28.1138790035587, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17537347, Length=312, Percent_Identity=29.1666666666667, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17561978, Length=258, Percent_Identity=27.5193798449612, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534739, Length=194, Percent_Identity=32.4742268041237, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508561, Length=298, Percent_Identity=26.1744966442953, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324307, Length=329, Percent_Identity=31.9148936170213, Blast_Score=159, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6325141, Length=299, Percent_Identity=29.0969899665552, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6323999, Length=260, Percent_Identity=27.3076923076923, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321244, Length=234, Percent_Identity=27.3504273504274, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325325, Length=212, Percent_Identity=25.9433962264151, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281360899, Length=299, Percent_Identity=34.7826086956522, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24642144, Length=299, Percent_Identity=34.7826086956522, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24642142, Length=299, Percent_Identity=34.7826086956522, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24642146, Length=299, Percent_Identity=34.7826086956522, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24641720, Length=336, Percent_Identity=32.4404761904762, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI281360801, Length=336, Percent_Identity=32.4404761904762, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI281360799, Length=336, Percent_Identity=32.4404761904762, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24657891, Length=273, Percent_Identity=26.007326007326, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644244, Length=307, Percent_Identity=26.0586319218241, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34277; Mature: 34146

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRLYEHPIFLEHVTPAGHPERSDRIRAINVALEHPNFERLERRQAPEASEDAVLLAHP
CCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCCCCCCCEEEEECC
EEHLTAVMREIPDEEDRINQLEADTYASQKSLQAALTGIGGAMAAVDDVFSGAADNVFVA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEE
ARPPGHHAEKMTAMGFCFFNNAAIAARHAQKRHGAERVAIIDWDVHHGNGTQDIFWDDPS
ECCCCCHHHHHHHEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEECCCC
VLFCSTHQMPLYPGSGAKDEKGKHNTIVNAPLSPNVGSDHFREAFKSRVLPAVADFRPDL
EEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCHHHHCCCCCE
IIISAGFDAHHRDPLAQINLTGEDFDWATGRVLELADRHAKNRVVSLLEGGYDLEGLAES
EEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AGMHILRMMKG
HHHHHHHHHCC
>Mature Secondary Structure 
STRLYEHPIFLEHVTPAGHPERSDRIRAINVALEHPNFERLERRQAPEASEDAVLLAHP
CCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCCCCCCCEEEEECC
EEHLTAVMREIPDEEDRINQLEADTYASQKSLQAALTGIGGAMAAVDDVFSGAADNVFVA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEE
ARPPGHHAEKMTAMGFCFFNNAAIAARHAQKRHGAERVAIIDWDVHHGNGTQDIFWDDPS
ECCCCCHHHHHHHEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEECCCC
VLFCSTHQMPLYPGSGAKDEKGKHNTIVNAPLSPNVGSDHFREAFKSRVLPAVADFRPDL
EEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCHHHHCCCCCE
IIISAGFDAHHRDPLAQINLTGEDFDWATGRVLELADRHAKNRVVSLLEGGYDLEGLAES
EEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AGMHILRMMKG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]