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The map label for this gene is mcpA [H]

Identifier: 209548169

GI number: 209548169

Start: 584684

End: 586621

Strand: Direct

Name: mcpA [H]

Synonym: Rleg2_0563

Alternate gene names: 209548169

Gene position: 584684-586621 (Clockwise)

Preceding gene: 209548168

Following gene: 209548171

Centisome position: 12.88

GC content: 66.1

Gene sequence:

>1938_bases
ATGTCCGCCAAAAACATATCCTTGAACGGGAAGCTTGCGGCCACCTTCGCAGCCCTCATTCTTATTTTCGTCGCCGTTTC
CGCCTTCGTTTATTCCAAGGCGACGGCGTCGGCCGCCGCCTCCGCCGAGCAGGAAAAGTCCGAGCTGCTCGTCAACCAGA
TCGACGATGCGCTGCAGGCGATGCTCGAGCAGGCCGTCAACCTGCGCGGCTTCATCCTTTTCCGCAGCGACAGCACCTAT
GGCGATGTCTTCGCCAACCGCGAGCGCATGCTGAAGGCGATTGCCGCCGCCAAGCAGACGGCGGCCGGCGAGCCGCAGCT
GGTCGAGATGATCGACGGCATGCAGAAGGCCGCCGACCTCTACTTCCATGAACTGGCCGAGCCGCAGACCAAGGCGCGTA
AGGAAACCGACATGCCGATCGCCGACGTCGTCAAGATCGGCGTCAACGCCACCAAGGGCCAGCTCGACGGATTCCGCCAG
GCCTCGGCGAAGATCAAGGCCAGCGCCCGCGAAAAGTCCGACGCGCTTGCTGAAATCCGCGCCGATGCCAACAGCGATCT
GAAGACGACGCTGCTGGCCGGCGGTATCGTCGCCTCGCTTGCCGCCGCCGTGCTCGCCTGGCTGATGTCGCGCACCATCG
TCCGCCCGATCGTCGGCATGACGAGCGCCATGGACCGCCTCGCCGGCGGTGACAACGACATCACGGTCCCGGCGACCGAT
CGCGGCGACGAAGTCGGCCGCATGGCCCAGTCGGTGCTGGTCTTCAAGCAGGCGGCGATCGAGAAGCTGCGTCTTGCCGG
CGAGACCGACCGCATGCGCGGCGACGCCGAACGCCAGCGCCGGGCAACCGACGAGCAGAAGGCCCGCGAGGAAGGCGAGA
TCCGCCATGCCATCGACGCGTTGGCTGGCGGCCTTGCCGAGCTTGCCAATGGCGATATGGCCGGCCGTATCCAGACGCCG
TTCGCGCCGCAATATGACAGCCTGCGCAATGACTTCAACCATGCCGTCGAAAAGCTGCAGGCAGCCCTGCAATCGGTCGG
CCGCAACGCCTCGGCGATCAATGCCGGGGCCGGCGAAATCCGCTCGGCCGCCGACGATCTTGCTCACCGCACCGAGCAGC
AGGCCGCCGCCGTCGAACAGACCGCCGCAGCGCTCGAGCAGGTGACGACGACCGTCCGCGACAGCGCCAAGCGCGCCGAG
GATGCCGGCAATCTCGTCGAGCGCACCCGCCTCGGCGCCGAAAAATCCGGCGAAGTCGTCCGCAGGGCCGTCTCGGCGAT
GCAGCAGATCGAAAAATCCTCCGGCGAAATCTCCAACATTATCGGCGTCATCGACGACATCGCCTTCCAGACCAACCTCC
TGGCCTTGAACGCCGGCGTCGAAGCTGCGCGTGCCGGCGATGCAGGCAAGGGTTTCGCCGTCGTTGCCCAGGAAGTCCGC
GAACTCGCCCAGCGTTCGGCCAAGGCGGCGAAAGAGATCAAGGCGCTGATCACCACATCGGGCGAACAGGTCGTTGCCGG
CGTTTCGCTGGTCGGCGAGACCGGCAAGGCGCTGGAAGCAATCGTCGCCGAGGTGCAGGAGATCAACCACCACGTCAGCG
CGATCGTCACCGCCACCCGCGAACAGTCGATCGGCCTGCAGGAGATCAACACCGCCGTCAACAACATGGACCAGGGTACC
CAGCAGAACGCAGCCATGGTCGAGGAGCAGACCGCGGCAAGCCATGCGCTCGCCCAGGAGGCAAACGCGCTGGACGAATT
GCTGCACCAGTTCAAGCTCGGCCAGACGAGGCCGGATGCCGCACCGCGCGCCGCCGTTGCGAACGCCCGCCCGGTCGCTT
CTCCGGCCCGCGCTCTCGCCAACAAGGTCACCAAGGCCTTCGGCGGCCGCCAGGCAAGTGCCGCGGTTGCGGTTCAGGAG
GACTGGACGGAGTTCTGA

Upstream 100 bases:

>100_bases
TTCAACGCCGATCATGTTCTCAGTTTCAAACATCCCTGTGGTTGCGCCTCAAGCGCGACCCGTTTTCGCCGCGTCGACTG
TCGTCAGGAGAAATTCACCG

Downstream 100 bases:

>100_bases
GGGCGTTTTCTCACGGACGTTAAATGAAGAGGGCGGCGCAACGAATGCGCTGCCCTTTTTTGATAGACGAACCGCTATGA
TAAACACGAAAAATGTAACG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 645; Mature: 644

Protein sequence:

>645_residues
MSAKNISLNGKLAATFAALILIFVAVSAFVYSKATASAAASAEQEKSELLVNQIDDALQAMLEQAVNLRGFILFRSDSTY
GDVFANRERMLKAIAAAKQTAAGEPQLVEMIDGMQKAADLYFHELAEPQTKARKETDMPIADVVKIGVNATKGQLDGFRQ
ASAKIKASAREKSDALAEIRADANSDLKTTLLAGGIVASLAAAVLAWLMSRTIVRPIVGMTSAMDRLAGGDNDITVPATD
RGDEVGRMAQSVLVFKQAAIEKLRLAGETDRMRGDAERQRRATDEQKAREEGEIRHAIDALAGGLAELANGDMAGRIQTP
FAPQYDSLRNDFNHAVEKLQAALQSVGRNASAINAGAGEIRSAADDLAHRTEQQAAAVEQTAAALEQVTTTVRDSAKRAE
DAGNLVERTRLGAEKSGEVVRRAVSAMQQIEKSSGEISNIIGVIDDIAFQTNLLALNAGVEAARAGDAGKGFAVVAQEVR
ELAQRSAKAAKEIKALITTSGEQVVAGVSLVGETGKALEAIVAEVQEINHHVSAIVTATREQSIGLQEINTAVNNMDQGT
QQNAAMVEEQTAASHALAQEANALDELLHQFKLGQTRPDAAPRAAVANARPVASPARALANKVTKAFGGRQASAAVAVQE
DWTEF

Sequences:

>Translated_645_residues
MSAKNISLNGKLAATFAALILIFVAVSAFVYSKATASAAASAEQEKSELLVNQIDDALQAMLEQAVNLRGFILFRSDSTY
GDVFANRERMLKAIAAAKQTAAGEPQLVEMIDGMQKAADLYFHELAEPQTKARKETDMPIADVVKIGVNATKGQLDGFRQ
ASAKIKASAREKSDALAEIRADANSDLKTTLLAGGIVASLAAAVLAWLMSRTIVRPIVGMTSAMDRLAGGDNDITVPATD
RGDEVGRMAQSVLVFKQAAIEKLRLAGETDRMRGDAERQRRATDEQKAREEGEIRHAIDALAGGLAELANGDMAGRIQTP
FAPQYDSLRNDFNHAVEKLQAALQSVGRNASAINAGAGEIRSAADDLAHRTEQQAAAVEQTAAALEQVTTTVRDSAKRAE
DAGNLVERTRLGAEKSGEVVRRAVSAMQQIEKSSGEISNIIGVIDDIAFQTNLLALNAGVEAARAGDAGKGFAVVAQEVR
ELAQRSAKAAKEIKALITTSGEQVVAGVSLVGETGKALEAIVAEVQEINHHVSAIVTATREQSIGLQEINTAVNNMDQGT
QQNAAMVEEQTAASHALAQEANALDELLHQFKLGQTRPDAAPRAAVANARPVASPARALANKVTKAFGGRQASAAVAVQE
DWTEF
>Mature_644_residues
SAKNISLNGKLAATFAALILIFVAVSAFVYSKATASAAASAEQEKSELLVNQIDDALQAMLEQAVNLRGFILFRSDSTYG
DVFANRERMLKAIAAAKQTAAGEPQLVEMIDGMQKAADLYFHELAEPQTKARKETDMPIADVVKIGVNATKGQLDGFRQA
SAKIKASAREKSDALAEIRADANSDLKTTLLAGGIVASLAAAVLAWLMSRTIVRPIVGMTSAMDRLAGGDNDITVPATDR
GDEVGRMAQSVLVFKQAAIEKLRLAGETDRMRGDAERQRRATDEQKAREEGEIRHAIDALAGGLAELANGDMAGRIQTPF
APQYDSLRNDFNHAVEKLQAALQSVGRNASAINAGAGEIRSAADDLAHRTEQQAAAVEQTAAALEQVTTTVRDSAKRAED
AGNLVERTRLGAEKSGEVVRRAVSAMQQIEKSSGEISNIIGVIDDIAFQTNLLALNAGVEAARAGDAGKGFAVVAQEVRE
LAQRSAKAAKEIKALITTSGEQVVAGVSLVGETGKALEAIVAEVQEINHHVSAIVTATREQSIGLQEINTAVNNMDQGTQ
QNAAMVEEQTAASHALAQEANALDELLHQFKLGQTRPDAAPRAAVANARPVASPARALANKVTKAFGGRQASAAVAVQED
WTEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=284, Percent_Identity=44.0140845070423, Blast_Score=199, Evalue=6e-52,
Organism=Escherichia coli, GI2367378, Length=324, Percent_Identity=42.2839506172839, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1788195, Length=313, Percent_Identity=42.4920127795527, Blast_Score=192, Evalue=8e-50,
Organism=Escherichia coli, GI1788194, Length=257, Percent_Identity=45.136186770428, Blast_Score=185, Evalue=8e-48,
Organism=Escherichia coli, GI1789453, Length=250, Percent_Identity=38, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68173; Mature: 68041

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKNISLNGKLAATFAALILIFVAVSAFVYSKATASAAASAEQEKSELLVNQIDDALQA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLEQAVNLRGFILFRSDSTYGDVFANRERMLKAIAAAKQTAAGEPQLVEMIDGMQKAADL
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
YFHELAEPQTKARKETDMPIADVVKIGVNATKGQLDGFRQASAKIKASAREKSDALAEIR
HHHHHCCHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADANSDLKTTLLAGGIVASLAAAVLAWLMSRTIVRPIVGMTSAMDRLAGGDNDITVPATD
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
RGDEVGRMAQSVLVFKQAAIEKLRLAGETDRMRGDAERQRRATDEQKAREEGEIRHAIDA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHH
LAGGLAELANGDMAGRIQTPFAPQYDSLRNDFNHAVEKLQAALQSVGRNASAINAGAGEI
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
RSAADDLAHRTEQQAAAVEQTAAALEQVTTTVRDSAKRAEDAGNLVERTRLGAEKSGEVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RRAVSAMQQIEKSSGEISNIIGVIDDIAFQTNLLALNAGVEAARAGDAGKGFAVVAQEVR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCHHHHHHHHHH
ELAQRSAKAAKEIKALITTSGEQVVAGVSLVGETGKALEAIVAEVQEINHHVSAIVTATR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQSIGLQEINTAVNNMDQGTQQNAAMVEEQTAASHALAQEANALDELLHQFKLGQTRPDA
HHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
APRAAVANARPVASPARALANKVTKAFGGRQASAAVAVQEDWTEF
CCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHEEEEHHCCCCC
>Mature Secondary Structure 
SAKNISLNGKLAATFAALILIFVAVSAFVYSKATASAAASAEQEKSELLVNQIDDALQA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLEQAVNLRGFILFRSDSTYGDVFANRERMLKAIAAAKQTAAGEPQLVEMIDGMQKAADL
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
YFHELAEPQTKARKETDMPIADVVKIGVNATKGQLDGFRQASAKIKASAREKSDALAEIR
HHHHHCCHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADANSDLKTTLLAGGIVASLAAAVLAWLMSRTIVRPIVGMTSAMDRLAGGDNDITVPATD
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
RGDEVGRMAQSVLVFKQAAIEKLRLAGETDRMRGDAERQRRATDEQKAREEGEIRHAIDA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHH
LAGGLAELANGDMAGRIQTPFAPQYDSLRNDFNHAVEKLQAALQSVGRNASAINAGAGEI
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
RSAADDLAHRTEQQAAAVEQTAAALEQVTTTVRDSAKRAEDAGNLVERTRLGAEKSGEVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RRAVSAMQQIEKSSGEISNIIGVIDDIAFQTNLLALNAGVEAARAGDAGKGFAVVAQEVR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCHHHHHHHHHH
ELAQRSAKAAKEIKALITTSGEQVVAGVSLVGETGKALEAIVAEVQEINHHVSAIVTATR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQSIGLQEINTAVNNMDQGTQQNAAMVEEQTAASHALAQEANALDELLHQFKLGQTRPDA
HHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
APRAAVANARPVASPARALANKVTKAFGGRQASAAVAVQEDWTEF
CCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]