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The map label for this gene is ubiA [H]

Identifier: 209548149

GI number: 209548149

Start: 562166

End: 563125

Strand: Direct

Name: ubiA [H]

Synonym: Rleg2_0543

Alternate gene names: 209548149

Gene position: 562166-563125 (Clockwise)

Preceding gene: 209548148

Following gene: 209548151

Centisome position: 12.39

GC content: 62.81

Gene sequence:

>960_bases
ATGCAAGATACCGGCGACTTCAACGATCGCGTTTCCGACGCACCTTCCGATAACTGGGTCTACCGGATCCTGCCGCCATG
GCTGTGGCCCTATGCGCAGCTGGCGCGATGGGATCGGCCGATCGGCTGGCAGTTGCTGATGTGGCCGTGTTTCTGGTCGG
CAACCCTTGCCGCCAATGCGGCGATCGGCGAGGGGCTCTATTCCGGCAGCCTGCTGGTGTCTCACCTTGTGCTCTATTTC
ATCGGCGCCGTCGCCATGCGCGGCGCCGGCTGCACCTATAACGATCTCGTCGACCACGAGATCGACATGGAAGTGGCGCG
CACGCGCTCGCGTCCGCTGCCCTCCGGCCGCGTCACGCGCGCCCATGCGAAGATCTTCATCGGCCTGCAGGCCCTCGTCG
GGCTTTTCGTGCTCTTGCAGTTCAACTGGTTCACGGTCTTCCTCGGTGTGCTCTCGCTCGGCATCGTGGCGCTTTATCCC
TACGCCAAACGTTTCACCGACTGGCCGCAATTCTACCTGGGGCTTGCCTTCTCCTGGGGCGCGCTGATGGGCTGGGCCGG
CATTTTGGGCGGCCTCTCCTTCGCCGCCGTCCTGCTTTATGCCGCCTCGGTCGCCTGGACGATCGGTTACGACACGATTT
ACGCCCATCAGGACAAGGAGGACGACGAACTGATAGGCGTTCGTTCCACCGCGCGCCTGTTCGGCGACAGGACGCGGGTA
TGGCTGATCGGCCTCTATGGGCTGACGCTAGTGCTGATGTTTGCCGCTTTCGCGCTGGCCGGCGCCAATCTCATCGCGTT
TCTGGCCTTGTTCGGCGCCGCCGGCATGTTCGCCTGGCAGATCGTCCGGCTCGATATCAATGATGCCGCCCAATGCCTGG
CGCTCTTCAAGTCGAACAATCGCGTCGGCCTGATCATCTTCTTCGGCCTCTTCGTCTCGCTGCTCTTCGCCATTCCCTGA

Upstream 100 bases:

>100_bases
CATGTCGCCCGGAAGTGCGTAGCGGTTCCGGGATAACGACATCCATGAGACAGAGAGATCGCTTCTTGACCGGATCGCCG
GCCGGTCGCTAGATGGCGGC

Downstream 100 bases:

>100_bases
ATGGAGCGACGCGCAAAACGACAAACCCGGCGCGGGCGCCGGGTTTCAAATGTGTGCGAAAACGAAGTGTCGCGAAATCG
CTCAGTTACGGGCGATGATT

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MQDTGDFNDRVSDAPSDNWVYRILPPWLWPYAQLARWDRPIGWQLLMWPCFWSATLAANAAIGEGLYSGSLLVSHLVLYF
IGAVAMRGAGCTYNDLVDHEIDMEVARTRSRPLPSGRVTRAHAKIFIGLQALVGLFVLLQFNWFTVFLGVLSLGIVALYP
YAKRFTDWPQFYLGLAFSWGALMGWAGILGGLSFAAVLLYAASVAWTIGYDTIYAHQDKEDDELIGVRSTARLFGDRTRV
WLIGLYGLTLVLMFAAFALAGANLIAFLALFGAAGMFAWQIVRLDINDAAQCLALFKSNNRVGLIIFFGLFVSLLFAIP

Sequences:

>Translated_319_residues
MQDTGDFNDRVSDAPSDNWVYRILPPWLWPYAQLARWDRPIGWQLLMWPCFWSATLAANAAIGEGLYSGSLLVSHLVLYF
IGAVAMRGAGCTYNDLVDHEIDMEVARTRSRPLPSGRVTRAHAKIFIGLQALVGLFVLLQFNWFTVFLGVLSLGIVALYP
YAKRFTDWPQFYLGLAFSWGALMGWAGILGGLSFAAVLLYAASVAWTIGYDTIYAHQDKEDDELIGVRSTARLFGDRTRV
WLIGLYGLTLVLMFAAFALAGANLIAFLALFGAAGMFAWQIVRLDINDAAQCLALFKSNNRVGLIIFFGLFVSLLFAIP
>Mature_319_residues
MQDTGDFNDRVSDAPSDNWVYRILPPWLWPYAQLARWDRPIGWQLLMWPCFWSATLAANAAIGEGLYSGSLLVSHLVLYF
IGAVAMRGAGCTYNDLVDHEIDMEVARTRSRPLPSGRVTRAHAKIFIGLQALVGLFVLLQFNWFTVFLGVLSLGIVALYP
YAKRFTDWPQFYLGLAFSWGALMGWAGILGGLSFAAVLLYAASVAWTIGYDTIYAHQDKEDDELIGVRSTARLFGDRTRV
WLIGLYGLTLVLMFAAFALAGANLIAFLALFGAAGMFAWQIVRLDINDAAQCLALFKSNNRVGLIIFFGLFVSLLFAIP

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=296, Percent_Identity=43.2432432432432, Blast_Score=211, Evalue=7e-55,
Organism=Escherichia coli, GI1790473, Length=284, Percent_Identity=33.8028169014084, Blast_Score=152, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17553718, Length=294, Percent_Identity=43.5374149659864, Blast_Score=218, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI32565247, Length=294, Percent_Identity=40.8163265306122, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17553720, Length=351, Percent_Identity=32.7635327635328, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32565245, Length=150, Percent_Identity=45.3333333333333, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI32565243, Length=149, Percent_Identity=44.9664429530201, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324370, Length=300, Percent_Identity=38.3333333333333, Blast_Score=172, Evalue=7e-44,
Organism=Drosophila melanogaster, GI21355567, Length=289, Percent_Identity=48.0968858131488, Blast_Score=248, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 35402; Mature: 35402

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDTGDFNDRVSDAPSDNWVYRILPPWLWPYAQLARWDRPIGWQLLMWPCFWSATLAANA
CCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AIGEGLYSGSLLVSHLVLYFIGAVAMRGAGCTYNDLVDHEIDMEVARTRSRPLPSGRVTR
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHCCCCCCCCCCHH
AHAKIFIGLQALVGLFVLLQFNWFTVFLGVLSLGIVALYPYAKRFTDWPQFYLGLAFSWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALMGWAGILGGLSFAAVLLYAASVAWTIGYDTIYAHQDKEDDELIGVRSTARLFGDRTRV
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCEECHHHHHHHHCCCCHH
WLIGLYGLTLVLMFAAFALAGANLIAFLALFGAAGMFAWQIVRLDINDAAQCLALFKSNN
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHCCC
RVGLIIFFGLFVSLLFAIP
CEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDTGDFNDRVSDAPSDNWVYRILPPWLWPYAQLARWDRPIGWQLLMWPCFWSATLAANA
CCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AIGEGLYSGSLLVSHLVLYFIGAVAMRGAGCTYNDLVDHEIDMEVARTRSRPLPSGRVTR
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHCCCCCCCCCCHH
AHAKIFIGLQALVGLFVLLQFNWFTVFLGVLSLGIVALYPYAKRFTDWPQFYLGLAFSWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALMGWAGILGGLSFAAVLLYAASVAWTIGYDTIYAHQDKEDDELIGVRSTARLFGDRTRV
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCEECHHHHHHHHCCCCHH
WLIGLYGLTLVLMFAAFALAGANLIAFLALFGAAGMFAWQIVRLDINDAAQCLALFKSNN
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHCCC
RVGLIIFFGLFVSLLFAIP
CEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA