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The map label for this gene is aroA [H]

Identifier: 209548139

GI number: 209548139

Start: 546324

End: 547586

Strand: Direct

Name: aroA [H]

Synonym: Rleg2_0533

Alternate gene names: 209548139

Gene position: 546324-547586 (Clockwise)

Preceding gene: 209548138

Following gene: 209548140

Centisome position: 12.04

GC content: 66.67

Gene sequence:

>1263_bases
ATGACACGCACAGCCAAACTCACCATCATCCCGCCGGGCAAGCCGCTTTCGGGCCGCGCCATGCCGCCGGGCTCCAAGTC
GATCACCAATCGGGCGCTGCTGCTCGCGGGTCTCGCCAAGGGTACGAGCCGGCTGACCGGCGCGCTGAAGAGCGACGATA
CGCGGTATATGGCCGATGCGCTGCGCGCCATGGGCGTTTCGATCGACGAGCCCGACGACACCACCTTCGTCGTCACCGGC
AGCGGCAGGCTCCAGCCGCCGAAGGCGCCGCTCTTCCTCGGCAATGCCGGCACGGCGACACGCTTCCTGACGGCTGCCGC
GGCTCTCGTGGACGGCACCGTCGTCGTTGACGGCGACGAGCACATGCGCAAGCGCCCGATCGGCCCGCTGGTCGAGGCGA
TGCGCACGCTTGGCATCGATGTAACTGCCGAAACCGGCTGCCCGCCGGTCACCGTCAAAGGCACCGGCCGCTTCCAGGCT
GACCGCATCCGCATCGATGGCGGCCTGTCCAGCCAATATGTCTCGGCCCTGCTGATGATGGCGGCCGGCGGCGACCGGCC
GTTCGATATCGAGCTCGTCGGCGAGGATATCGGGGCACTCGGTTATATCGATCTGACCACGGCGGCGATGAAAGCCTTCG
GCGCCAAGGTCGAAAAGACCAGCCCGGTCACCTGGCGGGTCGAGCCGACCGGCTACCGCGCCGCCGACTTCATCGTCGAG
CCCGATGCTTCGGCTGCGACCTATCTCTGGGCCGCCGAAGTCCTGACCGGCGGGGCGATCGATCTCGGCGTGCCCTCCGA
CGCCTTTTCGCAGCCGGATGCGCGCGCCTACGACATGATCGCCCGTTTTCCGCAGCTGCCGGCCGAAATCGACGGCTCGC
AGATGCAGGATGCGGTTCCGACGCTTGCCGTGCTTGCCGCCTTCAACGAGACGCCGGTCCGCTTCGTCGGCATCGCCAAC
CTGCGCGTTAAGGAATGCGACCGCATCCGGGCCCTCTCGAGCGGCCTCAACCGGATCCGTCCCGGCCTTGCCCGCGAAGA
GGGCGACGATCTGATCGTCAAGTCCGATCCGGCCCTTGTGGGAAAGCGTCTTCCGGCCGAGATCGACAGTTTCGCCGATC
ATCGCATCGCCATGAGCTTCGCGCTCGCCGGCCTGAAGATCGACGGCATCACCATTCTCGATCCCGATTGCGTCGGCAAG
ACCTTCCCCGCCTATTGGCGGACGCTCGCCGCCCTCGGCGTGACATATCAAGACAAGGATTGA

Upstream 100 bases:

>100_bases
CAAATTCTGACGATCCGGCATTTTGCCTTTGCAAGAAAGCGATTAAGAGCAAGGGCAGATAGCGGCCGGCAGTGGTCGCG
CGATGGACGAAAGACATAGC

Downstream 100 bases:

>100_bases
GGAGAAGCAGCCGAGGCTGCCGGCGGGGAGACAGGGATGGGACGTCGGTTTTTCGGATTTTGTTTGGCTCTGCTCTTGAT
GCTGGCCGCCTCGGCGGCCT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MTRTAKLTIIPPGKPLSGRAMPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRYMADALRAMGVSIDEPDDTTFVVTG
SGRLQPPKAPLFLGNAGTATRFLTAAAALVDGTVVVDGDEHMRKRPIGPLVEAMRTLGIDVTAETGCPPVTVKGTGRFQA
DRIRIDGGLSSQYVSALLMMAAGGDRPFDIELVGEDIGALGYIDLTTAAMKAFGAKVEKTSPVTWRVEPTGYRAADFIVE
PDASAATYLWAAEVLTGGAIDLGVPSDAFSQPDARAYDMIARFPQLPAEIDGSQMQDAVPTLAVLAAFNETPVRFVGIAN
LRVKECDRIRALSSGLNRIRPGLAREEGDDLIVKSDPALVGKRLPAEIDSFADHRIAMSFALAGLKIDGITILDPDCVGK
TFPAYWRTLAALGVTYQDKD

Sequences:

>Translated_420_residues
MTRTAKLTIIPPGKPLSGRAMPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRYMADALRAMGVSIDEPDDTTFVVTG
SGRLQPPKAPLFLGNAGTATRFLTAAAALVDGTVVVDGDEHMRKRPIGPLVEAMRTLGIDVTAETGCPPVTVKGTGRFQA
DRIRIDGGLSSQYVSALLMMAAGGDRPFDIELVGEDIGALGYIDLTTAAMKAFGAKVEKTSPVTWRVEPTGYRAADFIVE
PDASAATYLWAAEVLTGGAIDLGVPSDAFSQPDARAYDMIARFPQLPAEIDGSQMQDAVPTLAVLAAFNETPVRFVGIAN
LRVKECDRIRALSSGLNRIRPGLAREEGDDLIVKSDPALVGKRLPAEIDSFADHRIAMSFALAGLKIDGITILDPDCVGK
TFPAYWRTLAALGVTYQDKD
>Mature_419_residues
TRTAKLTIIPPGKPLSGRAMPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRYMADALRAMGVSIDEPDDTTFVVTGS
GRLQPPKAPLFLGNAGTATRFLTAAAALVDGTVVVDGDEHMRKRPIGPLVEAMRTLGIDVTAETGCPPVTVKGTGRFQAD
RIRIDGGLSSQYVSALLMMAAGGDRPFDIELVGEDIGALGYIDLTTAAMKAFGAKVEKTSPVTWRVEPTGYRAADFIVEP
DASAATYLWAAEVLTGGAIDLGVPSDAFSQPDARAYDMIARFPQLPAEIDGSQMQDAVPTLAVLAAFNETPVRFVGIANL
RVKECDRIRALSSGLNRIRPGLAREEGDDLIVKSDPALVGKRLPAEIDSFADHRIAMSFALAGLKIDGITILDPDCVGKT
FPAYWRTLAALGVTYQDKD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=428, Percent_Identity=37.3831775700935, Blast_Score=203, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320332, Length=456, Percent_Identity=35.3070175438597, Blast_Score=208, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 44476; Mature: 44344

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTAKLTIIPPGKPLSGRAMPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRYMADA
CCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHEEHHHHCCHHHHHCCCCCCCHHHHHHH
LRAMGVSIDEPDDTTFVVTGSGRLQPPKAPLFLGNAGTATRFLTAAAALVDGTVVVDGDE
HHHHCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCEEEECCHH
HMRKRPIGPLVEAMRTLGIDVTAETGCPPVTVKGTGRFQADRIRIDGGLSSQYVSALLMM
HHHHCCCCHHHHHHHHHCCEEEECCCCCCEEEECCCCEEEEEEEECCCCCHHHHHHHHHH
AAGGDRPFDIELVGEDIGALGYIDLTTAAMKAFGAKVEKTSPVTWRVEPTGYRAADFIVE
HCCCCCCEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEEEC
PDASAATYLWAAEVLTGGAIDLGVPSDAFSQPDARAYDMIARFPQLPAEIDGSQMQDAVP
CCCCCHHHHHHHHHHCCCEEEECCCCHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHH
TLAVLAAFNETPVRFVGIANLRVKECDRIRALSSGLNRIRPGLAREEGDDLIVKSDPALV
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHH
GKRLPAEIDSFADHRIAMSFALAGLKIDGITILDPDCVGKTFPAYWRTLAALGVTYQDKD
CCCCCHHHHHHHHHHHEEHHHHCCEEECCEEEECCHHCCCCCHHHHHHHHHHCCEECCCC
>Mature Secondary Structure 
TRTAKLTIIPPGKPLSGRAMPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRYMADA
CCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHEEHHHHCCHHHHHCCCCCCCHHHHHHH
LRAMGVSIDEPDDTTFVVTGSGRLQPPKAPLFLGNAGTATRFLTAAAALVDGTVVVDGDE
HHHHCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCEEEECCHH
HMRKRPIGPLVEAMRTLGIDVTAETGCPPVTVKGTGRFQADRIRIDGGLSSQYVSALLMM
HHHHCCCCHHHHHHHHHCCEEEECCCCCCEEEECCCCEEEEEEEECCCCCHHHHHHHHHH
AAGGDRPFDIELVGEDIGALGYIDLTTAAMKAFGAKVEKTSPVTWRVEPTGYRAADFIVE
HCCCCCCEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEEEC
PDASAATYLWAAEVLTGGAIDLGVPSDAFSQPDARAYDMIARFPQLPAEIDGSQMQDAVP
CCCCCHHHHHHHHHHCCCEEEECCCCHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHH
TLAVLAAFNETPVRFVGIANLRVKECDRIRALSSGLNRIRPGLAREEGDDLIVKSDPALV
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHH
GKRLPAEIDSFADHRIAMSFALAGLKIDGITILDPDCVGKTFPAYWRTLAALGVTYQDKD
CCCCCHHHHHHHHHHHEEHHHHCCEEECCEEEECCHHCCCCCHHHHHHHHHHCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA