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The map label for this gene is corA [H]

Identifier: 209548113

GI number: 209548113

Start: 522017

End: 523009

Strand: Direct

Name: corA [H]

Synonym: Rleg2_0507

Alternate gene names: 209548113

Gene position: 522017-523009 (Clockwise)

Preceding gene: 209548112

Following gene: 209548114

Centisome position: 11.5

GC content: 59.11

Gene sequence:

>993_bases
ATGGAAAGGCTGCCGGTGATCACCGCTTACTGTTCCAATTGCAGGTCGGTCGAGATCCGCGATCTGTCGCATCCCGCATC
CTTCCCCGAGGATGTCGTCTGGATCGACATGATCGAGCCGAGCCGCGATGAAGAGCTTTATGTCGAGAAGGTGCTCGGCA
TCGAGGTTCCGACCCGTGATGATCTCAAGGATATCGAGCCCTCCGCCCGTCTCTACGTCGAAAACGACGCCGTCTTCATG
ACCGCCTCGCTGCTCTGGAAGGCCGATACCGACGCGCCGACGCTGACCGATGTCGCCTTCATCCTGGCCGGAAACCGGCT
GGTCACCATCCGCTACGCCCATCCCAAATCCTTTGCGCTGTTCATCGCTGCCCTTCACCGGCTGCCGGAAAACTGGCGCA
GCGGCGCTGCCCTTCTCGCCAAGTTGCTGGAGACGATCGTCGACCGCACCGCCGAGATTCTCGAAATCTCCGTCGCGCGC
CTCGACATCTTGTCGATGCATGTCTTCGGCGACCGGGCGAAGAAGACGCGCAAGCCGTCGAACTATCTCGAGGAGAAGCT
GCGCGATATCGCCGGTTATCACCGGATGATCAGCAAGGTGCGCGACAGCCTCGGTTCGCTGTCCCGCCTGCTCACCTTCT
TCCACACGATCCCGGCGGTCCAGCAGGACCGCGAAACGAAGGAACTCTGCCGCACTCTCTCGCGCGACATCCAGTCGCTG
TCGGAGCATGCCGCCTTCGTTGCAGGCAACATCACCTTCCTGCTCGACGCTTCGCTCGGTCTGATCAACATCGAGCAGAA
TTCGATCATCAAGATTTTCTCGATTGCCTCGGTGGTGTTCTTGCCGCCGACATTGGTCGCCTCCATCTATGGTATGAATT
TTCAGGTCATGCCGGAATTGGCCTGGGCCGCGGGTTATCCTTATTCGCTGGCCCTGATGGTGATATCAGCCGTCATCCCT
TTTTTCTTTTTCCGCTGGAAAGGCTGGCTCTGA

Upstream 100 bases:

>100_bases
CCTTTAAGGCTGGATGCAGCCGGAGTTGTATGACCTTTTTTGATCCGCTTCCGCTGGCACCTGGGACGAGCGACCCTCGC
GTTGCCGCGCTGGCGGCCGC

Downstream 100 bases:

>100_bases
GGAGCCTGTTGCAACTTCATGTCCGCAGAGAGCCATCCGAACGAATCCCAGATGACGCCGAAGAAGCTGTTCTATCTTGC
GCTCGGTTCCGTCGGCGTCG

Product: Mg2 transporter CorA family protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MERLPVITAYCSNCRSVEIRDLSHPASFPEDVVWIDMIEPSRDEELYVEKVLGIEVPTRDDLKDIEPSARLYVENDAVFM
TASLLWKADTDAPTLTDVAFILAGNRLVTIRYAHPKSFALFIAALHRLPENWRSGAALLAKLLETIVDRTAEILEISVAR
LDILSMHVFGDRAKKTRKPSNYLEEKLRDIAGYHRMISKVRDSLGSLSRLLTFFHTIPAVQQDRETKELCRTLSRDIQSL
SEHAAFVAGNITFLLDASLGLINIEQNSIIKIFSIASVVFLPPTLVASIYGMNFQVMPELAWAAGYPYSLALMVISAVIP
FFFFRWKGWL

Sequences:

>Translated_330_residues
MERLPVITAYCSNCRSVEIRDLSHPASFPEDVVWIDMIEPSRDEELYVEKVLGIEVPTRDDLKDIEPSARLYVENDAVFM
TASLLWKADTDAPTLTDVAFILAGNRLVTIRYAHPKSFALFIAALHRLPENWRSGAALLAKLLETIVDRTAEILEISVAR
LDILSMHVFGDRAKKTRKPSNYLEEKLRDIAGYHRMISKVRDSLGSLSRLLTFFHTIPAVQQDRETKELCRTLSRDIQSL
SEHAAFVAGNITFLLDASLGLINIEQNSIIKIFSIASVVFLPPTLVASIYGMNFQVMPELAWAAGYPYSLALMVISAVIP
FFFFRWKGWL
>Mature_330_residues
MERLPVITAYCSNCRSVEIRDLSHPASFPEDVVWIDMIEPSRDEELYVEKVLGIEVPTRDDLKDIEPSARLYVENDAVFM
TASLLWKADTDAPTLTDVAFILAGNRLVTIRYAHPKSFALFIAALHRLPENWRSGAALLAKLLETIVDRTAEILEISVAR
LDILSMHVFGDRAKKTRKPSNYLEEKLRDIAGYHRMISKVRDSLGSLSRLLTFFHTIPAVQQDRETKELCRTLSRDIQSL
SEHAAFVAGNITFLLDASLGLINIEQNSIIKIFSIASVVFLPPTLVASIYGMNFQVMPELAWAAGYPYSLALMVISAVIP
FFFFRWKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=305, Percent_Identity=36.7213114754098, Blast_Score=181, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 37293; Mature: 37293

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLPVITAYCSNCRSVEIRDLSHPASFPEDVVWIDMIEPSRDEELYVEKVLGIEVPTRD
CCCCCCHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCC
DLKDIEPSARLYVENDAVFMTASLLWKADTDAPTLTDVAFILAGNRLVTIRYAHPKSFAL
CHHHCCCCCEEEEECCCEEEEEEHHEECCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHH
FIAALHRLPENWRSGAALLAKLLETIVDRTAEILEISVARLDILSMHVFGDRAKKTRKPS
HHHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCH
NYLEEKLRDIAGYHRMISKVRDSLGSLSRLLTFFHTIPAVQQDRETKELCRTLSRDIQSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
SEHAAFVAGNITFLLDASLGLINIEQNSIIKIFSIASVVFLPPTLVASIYGMNFQVMPEL
HHHHHHHCCCEEEEEECCCCEEEECCCCEEHHHHHHHHHHCCHHHHHHHHCCCEEEHHHH
AWAAGYPYSLALMVISAVIPFFFFRWKGWL
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MERLPVITAYCSNCRSVEIRDLSHPASFPEDVVWIDMIEPSRDEELYVEKVLGIEVPTRD
CCCCCCHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCC
DLKDIEPSARLYVENDAVFMTASLLWKADTDAPTLTDVAFILAGNRLVTIRYAHPKSFAL
CHHHCCCCCEEEEECCCEEEEEEHHEECCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHH
FIAALHRLPENWRSGAALLAKLLETIVDRTAEILEISVARLDILSMHVFGDRAKKTRKPS
HHHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCH
NYLEEKLRDIAGYHRMISKVRDSLGSLSRLLTFFHTIPAVQQDRETKELCRTLSRDIQSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
SEHAAFVAGNITFLLDASLGLINIEQNSIIKIFSIASVVFLPPTLVASIYGMNFQVMPEL
HHHHHHHCCCEEEEEECCCCEEEECCCCEEHHHHHHHHHHCCHHHHHHHHCCCEEEHHHH
AWAAGYPYSLALMVISAVIPFFFFRWKGWL
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]