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The map label for this gene is yciL [C]

Identifier: 209548084

GI number: 209548084

Start: 488816

End: 490885

Strand: Direct

Name: yciL [C]

Synonym: Rleg2_0477

Alternate gene names: 209548084

Gene position: 488816-490885 (Clockwise)

Preceding gene: 209548082

Following gene: 209548085

Centisome position: 10.77

GC content: 68.74

Gene sequence:

>2070_bases
ATGACACCCAAAGACAAGCCAAAACGCCCGGGCGCAAAGCCCTTTTCACGCGACAGCGGGCCGAAGGCCGGCGCGAAGTC
GGGCGGCACGAAGCCGGCAAAGGCTGCGATCGCGGCCGAGACCGAAGGCGAGGCCAAGGCCGAACGCATTTCCAAGGTGA
TGGCACGCGCCGGCGTCGCCTCCCGCCGCGACATCGAGCGCATGATCATGGAAGGCCGCGTGACGCTGAACGGCGCGGTT
CTCGACACCCCGGTCGTCAACGTCACGCTCGCCGATCGCATCGAGGTCGACGGCGTGCCGATCCGCGGCATCGAGCGCAC
CAGGTTGTGGCTCTATCATAAGCCGGCCGGGCTGGTGACCACCAATGCCGATCCCGAAGGCCGCGCGACCGTCTTCGACA
ACCTGCCGGAAGAACTGCCGCGCGTCATGTCGATCGGCCGCCTCGATATCAACACCGAGGGCCTGCTGCTGCTGACCAAT
GACGGCGGTCTTGCCCGCGCGCTCGAACTGCCGGCCACCGGCTGGCTGCGCCGCTACCGTGTCCGCGCCCATGGCGACAT
CGATCAGGACGCGCTCGACAAGCTGAAGGACGGCATCGCCGTCGACGGCGTGCTCTACGGTTCGATCGAGGCGACGCTCG
ACCGCACGCAGGGCTCGAACGTCTGGATCACCATGGGTCTTCGCGAAGGCAAGAACCGCGAAATCAAGAACGTGATGGGC
GCTCTCGGCCTCGACGTCAACCGTCTGATCCGCATCTCCTATGGCCCGTTCCAGCTCGGCGACTTGCCGGAAGGCCATGT
CATCGAAGTGCGCGGCCGCACGCTTCGCGACCAGCTCGGCCCGCGCCTGATCGAGGAAGCCAAGGCGAATTTCGATGCGC
CGATCTACAATGCGCCGGCCGTCGCCGCCGAGGAAGAGGCTGAAGCCCCAGTGCCGGAACGGCGCGAGCAACGTCCGCGC
CGCGACGAGGACAAGCGCGAACGGGCGCTGAGCCGCCTCGACACCAAGCGCGACGATCGCCGCGGTGGCGGGCGTAGAGA
TGACGACCGCCGCGATGGCGGACGCTTCGACGACGACAAGCCGAAACGTCCCCAGCCGCTCGGCCAGCGCCGCAGCGCCA
ATGTCTGGATGGCGCCGGGTGCCCGGCCGCTCGGTGAAAAGGCAGCGGCGAAAGCCGCCAAGAATGAGCAGACCGCGCGG
CGCGGCGAGCACGCGCCGGCAAAGGGCACTGGTTCCCACCATATCGAGGATCGCCCGCGCACGCAGATCAATCGCGTGCG
CGAAGAGGACGGCGAATGGATCCGCTCGAGCGAGCAGCCCAACCGTAAGGATGAGGGCGAAGGCCGCAAGCGATCGTTCG
GGGATCGGCCGGCCCGCGAAGACCGCGGTTTTGGCGACCGCCCGGCCCGCGGCGACCGCCGCCCCCGTGAAGGGGGTGAC
GAACGTCCGCGTAGCAGAAGCTCGGCCGGCGAAGGCCGGCCGGAGCGTCCGCGCGGCGATCGGCCTTTCGGTGATCGTCC
CTCGCGTGGTGATCGTCCCTCGCGTGGTGATCGTCCCTTCGGCGACAAGCCGCGCGGTGATCGCAAACCGCGTGGCGATG
GGGACGAACGTCCTCGTGCCGCCAGAGCCTCCACCGGTGAGGCGCGTTCGGAGCGTCCGCGCGGTGACCGGCCTTTCGGC
GATCGTCCTTCACGTGGCGACCGCCCCTTCGGCGACAAGCCGCGGGGTGAACGCAGGCCGCGCGAGGAGGGTGATGAGCG
CCCGCGCGCAGCCAGAAGTTTTGCCGGCGAGGGCCGCTCCGAGCGTCCGCGTGGCGAAAAATCCTTCGGCGACAAGTCCC
CAGGCGGCAGGCCTTCGAGCGGGAAGCCTTCGGGCGATAAGCCGCGCGGCAAGGGCTTTGGCGCCAAGCCGGGCGGGGCC
AAGAGTTTTTCCGGTAAGCCGAAGGGCGCCAAGCCTGGTGGTGAAAGGGCAGGCGGCGACAGGCCAGGCGGCGACAGGCC
TGCGGGCGGGCCGTCCAGAAGTGGTGGAAAAGGAAAGGGAATGACACGCGGTGCGGATCGTCGGCGGTGA

Upstream 100 bases:

>100_bases
CCATCTCCATGAAACGATTTGTCTTCACGATCGCAAGAATTTCCACTTAACCGCAGATGCGTGACCTGATAGACAGGCCC
AAAAGGCAGGCAAACAACAA

Downstream 100 bases:

>100_bases
ATTTCGCGGACGGCCTCTCGCCGTGCCAAAATCCAATGAGATCCGGCCGACTGCTGACCGGACGCGCGAGAGCCTGTTCA
ATATATTGAGCCACGCCTAT

Product: RNA-binding S4 domain-containing protein

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 689; Mature: 688

Protein sequence:

>689_residues
MTPKDKPKRPGAKPFSRDSGPKAGAKSGGTKPAKAAIAAETEGEAKAERISKVMARAGVASRRDIERMIMEGRVTLNGAV
LDTPVVNVTLADRIEVDGVPIRGIERTRLWLYHKPAGLVTTNADPEGRATVFDNLPEELPRVMSIGRLDINTEGLLLLTN
DGGLARALELPATGWLRRYRVRAHGDIDQDALDKLKDGIAVDGVLYGSIEATLDRTQGSNVWITMGLREGKNREIKNVMG
ALGLDVNRLIRISYGPFQLGDLPEGHVIEVRGRTLRDQLGPRLIEEAKANFDAPIYNAPAVAAEEEAEAPVPERREQRPR
RDEDKRERALSRLDTKRDDRRGGGRRDDDRRDGGRFDDDKPKRPQPLGQRRSANVWMAPGARPLGEKAAAKAAKNEQTAR
RGEHAPAKGTGSHHIEDRPRTQINRVREEDGEWIRSSEQPNRKDEGEGRKRSFGDRPAREDRGFGDRPARGDRRPREGGD
ERPRSRSSAGEGRPERPRGDRPFGDRPSRGDRPSRGDRPFGDKPRGDRKPRGDGDERPRAARASTGEARSERPRGDRPFG
DRPSRGDRPFGDKPRGERRPREEGDERPRAARSFAGEGRSERPRGEKSFGDKSPGGRPSSGKPSGDKPRGKGFGAKPGGA
KSFSGKPKGAKPGGERAGGDRPGGDRPAGGPSRSGGKGKGMTRGADRRR

Sequences:

>Translated_689_residues
MTPKDKPKRPGAKPFSRDSGPKAGAKSGGTKPAKAAIAAETEGEAKAERISKVMARAGVASRRDIERMIMEGRVTLNGAV
LDTPVVNVTLADRIEVDGVPIRGIERTRLWLYHKPAGLVTTNADPEGRATVFDNLPEELPRVMSIGRLDINTEGLLLLTN
DGGLARALELPATGWLRRYRVRAHGDIDQDALDKLKDGIAVDGVLYGSIEATLDRTQGSNVWITMGLREGKNREIKNVMG
ALGLDVNRLIRISYGPFQLGDLPEGHVIEVRGRTLRDQLGPRLIEEAKANFDAPIYNAPAVAAEEEAEAPVPERREQRPR
RDEDKRERALSRLDTKRDDRRGGGRRDDDRRDGGRFDDDKPKRPQPLGQRRSANVWMAPGARPLGEKAAAKAAKNEQTAR
RGEHAPAKGTGSHHIEDRPRTQINRVREEDGEWIRSSEQPNRKDEGEGRKRSFGDRPAREDRGFGDRPARGDRRPREGGD
ERPRSRSSAGEGRPERPRGDRPFGDRPSRGDRPSRGDRPFGDKPRGDRKPRGDGDERPRAARASTGEARSERPRGDRPFG
DRPSRGDRPFGDKPRGERRPREEGDERPRAARSFAGEGRSERPRGEKSFGDKSPGGRPSSGKPSGDKPRGKGFGAKPGGA
KSFSGKPKGAKPGGERAGGDRPGGDRPAGGPSRSGGKGKGMTRGADRRR
>Mature_688_residues
TPKDKPKRPGAKPFSRDSGPKAGAKSGGTKPAKAAIAAETEGEAKAERISKVMARAGVASRRDIERMIMEGRVTLNGAVL
DTPVVNVTLADRIEVDGVPIRGIERTRLWLYHKPAGLVTTNADPEGRATVFDNLPEELPRVMSIGRLDINTEGLLLLTND
GGLARALELPATGWLRRYRVRAHGDIDQDALDKLKDGIAVDGVLYGSIEATLDRTQGSNVWITMGLREGKNREIKNVMGA
LGLDVNRLIRISYGPFQLGDLPEGHVIEVRGRTLRDQLGPRLIEEAKANFDAPIYNAPAVAAEEEAEAPVPERREQRPRR
DEDKRERALSRLDTKRDDRRGGGRRDDDRRDGGRFDDDKPKRPQPLGQRRSANVWMAPGARPLGEKAAAKAAKNEQTARR
GEHAPAKGTGSHHIEDRPRTQINRVREEDGEWIRSSEQPNRKDEGEGRKRSFGDRPAREDRGFGDRPARGDRRPREGGDE
RPRSRSSAGEGRPERPRGDRPFGDRPSRGDRPSRGDRPFGDKPRGDRKPRGDGDERPRAARASTGEARSERPRGDRPFGD
RPSRGDRPFGDKPRGERRPREEGDERPRAARSFAGEGRSERPRGEKSFGDKSPGGRPSSGKPSGDKPRGKGFGAKPGGAK
SFSGKPKGAKPGGERAGGDRPGGDRPAGGPSRSGGKGKGMTRGADRRR

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=311, Percent_Identity=35.3697749196142, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI87081838, Length=179, Percent_Identity=30.1675977653631, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790453, Length=222, Percent_Identity=27.9279279279279, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 75436; Mature: 75305

Theoretical pI: Translated: 11.19; Mature: 11.19

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPKDKPKRPGAKPFSRDSGPKAGAKSGGTKPAKAAIAAETEGEAKAERISKVMARAGVA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEECCCCHHHHHHHHHHHHHHCCH
SRRDIERMIMEGRVTLNGAVLDTPVVNVTLADRIEVDGVPIRGIERTRLWLYHKPAGLVT
HHHHHHHHHHHCCEEECCEEECCCEEEEEECCEEEECCCCCCCCCCCEEEEEECCCCEEE
TNADPEGRATVFDNLPEELPRVMSIGRLDINTEGLLLLTNDGGLARALELPATGWLRRYR
CCCCCCCCCHHHHHCHHHHHHHHHCCCEEECCCCEEEEECCCCCEEEEECCCHHHHHHHH
VRAHGDIDQDALDKLKDGIAVDGVLYGSIEATLDRTQGSNVWITMGLREGKNREIKNVMG
HHHCCCCCHHHHHHHHCCCEECEEEECCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
ALGLDVNRLIRISYGPFQLGDLPEGHVIEVRGRTLRDQLGPRLIEEAKANFDAPIYNAPA
HHCCCHHHEEEEECCCEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
VAAEEEAEAPVPERREQRPRRDEDKRERALSRLDTKRDDRRGGGRRDDDRRDGGRFDDDK
CCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PKRPQPLGQRRSANVWMAPGARPLGEKAAAKAAKNEQTARRGEHAPAKGTGSHHIEDRPR
CCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
TQINRVREEDGEWIRSSEQPNRKDEGEGRKRSFGDRPAREDRGFGDRPARGDRRPREGGD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCC
ERPRSRSSAGEGRPERPRGDRPFGDRPSRGDRPSRGDRPFGDKPRGDRKPRGDGDERPRA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
ARASTGEARSERPRGDRPFGDRPSRGDRPFGDKPRGERRPREEGDERPRAARSFAGEGRS
HHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
ERPRGEKSFGDKSPGGRPSSGKPSGDKPRGKGFGAKPGGAKSFSGKPKGAKPGGERAGGD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RPGGDRPAGGPSRSGGKGKGMTRGADRRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TPKDKPKRPGAKPFSRDSGPKAGAKSGGTKPAKAAIAAETEGEAKAERISKVMARAGVA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEECCCCHHHHHHHHHHHHHHCCH
SRRDIERMIMEGRVTLNGAVLDTPVVNVTLADRIEVDGVPIRGIERTRLWLYHKPAGLVT
HHHHHHHHHHHCCEEECCEEECCCEEEEEECCEEEECCCCCCCCCCCEEEEEECCCCEEE
TNADPEGRATVFDNLPEELPRVMSIGRLDINTEGLLLLTNDGGLARALELPATGWLRRYR
CCCCCCCCCHHHHHCHHHHHHHHHCCCEEECCCCEEEEECCCCCEEEEECCCHHHHHHHH
VRAHGDIDQDALDKLKDGIAVDGVLYGSIEATLDRTQGSNVWITMGLREGKNREIKNVMG
HHHCCCCCHHHHHHHHCCCEECEEEECCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
ALGLDVNRLIRISYGPFQLGDLPEGHVIEVRGRTLRDQLGPRLIEEAKANFDAPIYNAPA
HHCCCHHHEEEEECCCEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
VAAEEEAEAPVPERREQRPRRDEDKRERALSRLDTKRDDRRGGGRRDDDRRDGGRFDDDK
CCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PKRPQPLGQRRSANVWMAPGARPLGEKAAAKAAKNEQTARRGEHAPAKGTGSHHIEDRPR
CCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
TQINRVREEDGEWIRSSEQPNRKDEGEGRKRSFGDRPAREDRGFGDRPARGDRRPREGGD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCC
ERPRSRSSAGEGRPERPRGDRPFGDRPSRGDRPSRGDRPFGDKPRGDRKPRGDGDERPRA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
ARASTGEARSERPRGDRPFGDRPSRGDRPFGDKPRGERRPREEGDERPRAARSFAGEGRS
HHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
ERPRGEKSFGDKSPGGRPSSGKPSGDKPRGKGFGAKPGGAKSFSGKPKGAKPGGERAGGD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RPGGDRPAGGPSRSGGKGKGMTRGADRRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]