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The map label for this gene is dgdR [H]

Identifier: 209548045

GI number: 209548045

Start: 448647

End: 449615

Strand: Reverse

Name: dgdR [H]

Synonym: Rleg2_0438

Alternate gene names: 209548045

Gene position: 449615-448647 (Counterclockwise)

Preceding gene: 209548047

Following gene: 209548041

Centisome position: 9.91

GC content: 63.47

Gene sequence:

>969_bases
ATGGGTGACACAATGTCCGCGCCTCTTGATCTCGACCAGTTGCAGACTTTCATCGCCATCGTCGATTCCGGCAGCTTCAC
TAAGGCCGCCGACAGGGTCTACAAGACCCAATCGGCCGTTTCCATGCAGATGCGCCGTCTCGAAGAGCGCATCGGCAAGC
AGTTGTTCATCAAGGACGGACGCGGCAACCGGCTGACGGTCGAGGGTGAAAAACTGCTCAACTATGCCCGGCGCATCATC
CGTCTGAACAATGAGGCGATCGCCGCCTTCGACGACAACAGGCTGGAGGGCACGCTGCGCATCGGCACGCCGGATGATTA
TGCCGACCGCTACATGCCCGAAATCATCGGCCGCTTCGCCAAGACGCATCCGAATGTCGAGCTCTACATCGTCTGCGAGC
CCTCGGTGGATCTGGCCGAGCGCATGCACAAGGGCGAACTCGATATCGCGCTCGTCACCCACAATCCGCGCGAGCGCATG
TCAGATGTGGTGAGAACCGAGCCGCTCTGCTGGGTGGGGTCGGCCAACCACCCGATCCGCGACGACGCGCCGGTACCGCT
TGCCGTCGGCCGGCGCGATTGCCAATGGCGCCAGCTTGCCTGCTCGGCGCTCGATGCGGTGGGGCGTGAACACCAGATCC
TGTTCACCAGCTGGTCCTGCACCGTCGTTGCCGCTGCCGTGCTTGCCGGCATGGCGGTGTCGGTGATGCCGGAATCGGCG
CTGCGCACCGGCATGAAGGTGCTGAGCCAGGCGGACGGCTTTCCGGCGCTGCCGCCGGTGCAGATCGGCATCATGAAGCG
GCCGGGCGTTTCGCTCTCGCTGATGAACGCGATCACCGCGCATATCACCGCCTGCCTCGACAACATCACGCCGGCCGTCG
TCGACGACACGCTGGAAGCCGATGTCAAATCCGCCCAGGCACGCCTTTATCCCCGGCTGAAGGCCGCCAATATGGTACCG
AGCTGGTAA

Upstream 100 bases:

>100_bases
GGCGTCTGTCCTTCACTTTGCTTGATTTGCATCCCGAAGATGCCAAAGAGCTATTGATCAGTCCAACGAATGTTTCTAAT
GATTATCATCAGCTATCTTT

Downstream 100 bases:

>100_bases
GGGGTAAGAGGTAACAGCCCTCAGGCGGCGCGCTTCGTGGTCGCGGCGAAAAGGGAGGCGCGGATGACGCGTTTCCACTC
GTCGAGCATGCGTCGCGCCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MGDTMSAPLDLDQLQTFIAIVDSGSFTKAADRVYKTQSAVSMQMRRLEERIGKQLFIKDGRGNRLTVEGEKLLNYARRII
RLNNEAIAAFDDNRLEGTLRIGTPDDYADRYMPEIIGRFAKTHPNVELYIVCEPSVDLAERMHKGELDIALVTHNPRERM
SDVVRTEPLCWVGSANHPIRDDAPVPLAVGRRDCQWRQLACSALDAVGREHQILFTSWSCTVVAAAVLAGMAVSVMPESA
LRTGMKVLSQADGFPALPPVQIGIMKRPGVSLSLMNAITAHITACLDNITPAVVDDTLEADVKSAQARLYPRLKAANMVP
SW

Sequences:

>Translated_322_residues
MGDTMSAPLDLDQLQTFIAIVDSGSFTKAADRVYKTQSAVSMQMRRLEERIGKQLFIKDGRGNRLTVEGEKLLNYARRII
RLNNEAIAAFDDNRLEGTLRIGTPDDYADRYMPEIIGRFAKTHPNVELYIVCEPSVDLAERMHKGELDIALVTHNPRERM
SDVVRTEPLCWVGSANHPIRDDAPVPLAVGRRDCQWRQLACSALDAVGREHQILFTSWSCTVVAAAVLAGMAVSVMPESA
LRTGMKVLSQADGFPALPPVQIGIMKRPGVSLSLMNAITAHITACLDNITPAVVDDTLEADVKSAQARLYPRLKAANMVP
SW
>Mature_321_residues
GDTMSAPLDLDQLQTFIAIVDSGSFTKAADRVYKTQSAVSMQMRRLEERIGKQLFIKDGRGNRLTVEGEKLLNYARRIIR
LNNEAIAAFDDNRLEGTLRIGTPDDYADRYMPEIIGRFAKTHPNVELYIVCEPSVDLAERMHKGELDIALVTHNPRERMS
DVVRTEPLCWVGSANHPIRDDAPVPLAVGRRDCQWRQLACSALDAVGREHQILFTSWSCTVVAAAVLAGMAVSVMPESAL
RTGMKVLSQADGFPALPPVQIGIMKRPGVSLSLMNAITAHITACLDNITPAVVDDTLEADVKSAQARLYPRLKAANMVPS
W

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=270, Percent_Identity=33.7037037037037, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1787806, Length=253, Percent_Identity=24.901185770751, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=31.7241379310345, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI157672245, Length=181, Percent_Identity=28.7292817679558, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788297, Length=245, Percent_Identity=27.3469387755102, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787601, Length=155, Percent_Identity=29.6774193548387, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790399, Length=312, Percent_Identity=25, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790262, Length=145, Percent_Identity=28.2758620689655, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081904, Length=186, Percent_Identity=26.8817204301075, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI48994962, Length=152, Percent_Identity=27.6315789473684, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788887, Length=174, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789204, Length=310, Percent_Identity=26.4516129032258, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=24.4, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI145693105, Length=288, Percent_Identity=22.5694444444444, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87082132, Length=121, Percent_Identity=33.0578512396694, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787589, Length=140, Percent_Identity=30.7142857142857, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788296, Length=235, Percent_Identity=24.2553191489362, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786713, Length=69, Percent_Identity=44.9275362318841, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786401, Length=146, Percent_Identity=31.5068493150685, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787879, Length=187, Percent_Identity=28.3422459893048, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35510; Mature: 35379

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDTMSAPLDLDQLQTFIAIVDSGSFTKAADRVYKTQSAVSMQMRRLEERIGKQLFIKDG
CCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
RGNRLTVEGEKLLNYARRIIRLNNEAIAAFDDNRLEGTLRIGTPDDYADRYMPEIIGRFA
CCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHH
KTHPNVELYIVCEPSVDLAERMHKGELDIALVTHNPRERMSDVVRTEPLCWVGSANHPIR
HCCCCEEEEEEECCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCCCCC
DDAPVPLAVGRRDCQWRQLACSALDAVGREHQILFTSWSCTVVAAAVLAGMAVSVMPESA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCHHH
LRTGMKVLSQADGFPALPPVQIGIMKRPGVSLSLMNAITAHITACLDNITPAVVDDTLEA
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DVKSAQARLYPRLKAANMVPSW
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GDTMSAPLDLDQLQTFIAIVDSGSFTKAADRVYKTQSAVSMQMRRLEERIGKQLFIKDG
CCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
RGNRLTVEGEKLLNYARRIIRLNNEAIAAFDDNRLEGTLRIGTPDDYADRYMPEIIGRFA
CCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHH
KTHPNVELYIVCEPSVDLAERMHKGELDIALVTHNPRERMSDVVRTEPLCWVGSANHPIR
HCCCCEEEEEEECCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCCCCC
DDAPVPLAVGRRDCQWRQLACSALDAVGREHQILFTSWSCTVVAAAVLAGMAVSVMPESA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCHHH
LRTGMKVLSQADGFPALPPVQIGIMKRPGVSLSLMNAITAHITACLDNITPAVVDDTLEA
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DVKSAQARLYPRLKAANMVPSW
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]