Click here to switch to the map view.

The map label for this gene is tagA [H]

Identifier: 209547959

GI number: 209547959

Start: 352919

End: 353758

Strand: Direct

Name: tagA [H]

Synonym: Rleg2_0351

Alternate gene names: 209547959

Gene position: 352919-353758 (Clockwise)

Preceding gene: 209547958

Following gene: 209547960

Centisome position: 7.78

GC content: 61.55

Gene sequence:

>840_bases
ATGAATCTGATTGCGAACTTCGCGGTGCTCGCATCGCGGCGGACGATCTTCGATCTGCCGGTCTGCGATCTCGGCTGGGA
CGACGCCCTCGTTTTCATCAACGAGCTGGCCTCCATTCCCGTCGGCCAGACCGTGGTTTGCTTCGTCAACGCCCACAACA
TGCTGACCGCGCTTCACGATGACGAATATTACCGGATCATGTCGCACAATCTGGTGCTGCCGGATGGCATCGGTCTCAAC
ATCGCATCGCAGATCGCCCATGGTTCGCCGTTTCCCGCCAATCTGAACGGCACCGATTTTGTGCCGGCCTTCCTCACCTT
CATGGAGGCTCCGCGCCGCATCGGTCTGATCGGCGGCACGCGTTCGGTCGTCGAGGCGGCGGCGGAAAATTTCCGCAGGC
ATACGCCCTGGCATGAATTCGTTGTCGTTTCCGACGGTTATTTCGACAAGGTCGATTCGACTGAGGTCACTGAGGAGATC
GAGCGCCAGAAGCTCGATATCCTGATCGTCGGCATGGGAACGCCGCTGCAGGAAAAATGGGTCCACGATCATATCCGTGC
CGATCATGCGCGGCTGGTGCTGACGGTGGGCGCTCTCTTCGACTTCGTCTCCGGCGCCGTCCCGCGCGCGCCGAGGACGG
TGCGGATGATGCGGCTGGAATGGGCCTATCGCCTGCTGCAGGAGCCGACGCGCCTCTGGCGCCGCTACGTCATCGGCATC
CCGGTCTTCCTTTTCCATGTCCTGCGCTACCGCTTCCGCCGGCGCGAACGAATCCTCAGCCATCCGGAAGAACACAGCAC
CGCCCTGCAGCCGCGGTCGGAACACAAGAAGGCAAGCTGA

Upstream 100 bases:

>100_bases
CACGGCGGGACGCGACCGGGGCTTTCGAGGCCCGGTGCGGAGGTGTGGGCTTGTTTTCCGGGATGTCGGGCGCATGAAGC
ATCCTCGGCAGGAGGTAGGA

Downstream 100 bases:

>100_bases
CCCTCGCGTCTTTCCGGGGACGCTATGCATAGTTCTTACACGCTGCGGTTAACCATTTCTTTGCCATGAATATTTAGACT
GGCTTAATCATCTGCATCCG

Product: glycosyl transferase, WecB/TagA/CpsF family

Products: NA

Alternate protein names: Major teichoic acid biosynthesis protein A; N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase; UDP-N-acetylmannosamine transferase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MNLIANFAVLASRRTIFDLPVCDLGWDDALVFINELASIPVGQTVVCFVNAHNMLTALHDDEYYRIMSHNLVLPDGIGLN
IASQIAHGSPFPANLNGTDFVPAFLTFMEAPRRIGLIGGTRSVVEAAAENFRRHTPWHEFVVVSDGYFDKVDSTEVTEEI
ERQKLDILIVGMGTPLQEKWVHDHIRADHARLVLTVGALFDFVSGAVPRAPRTVRMMRLEWAYRLLQEPTRLWRRYVIGI
PVFLFHVLRYRFRRRERILSHPEEHSTALQPRSEHKKAS

Sequences:

>Translated_279_residues
MNLIANFAVLASRRTIFDLPVCDLGWDDALVFINELASIPVGQTVVCFVNAHNMLTALHDDEYYRIMSHNLVLPDGIGLN
IASQIAHGSPFPANLNGTDFVPAFLTFMEAPRRIGLIGGTRSVVEAAAENFRRHTPWHEFVVVSDGYFDKVDSTEVTEEI
ERQKLDILIVGMGTPLQEKWVHDHIRADHARLVLTVGALFDFVSGAVPRAPRTVRMMRLEWAYRLLQEPTRLWRRYVIGI
PVFLFHVLRYRFRRRERILSHPEEHSTALQPRSEHKKAS
>Mature_279_residues
MNLIANFAVLASRRTIFDLPVCDLGWDDALVFINELASIPVGQTVVCFVNAHNMLTALHDDEYYRIMSHNLVLPDGIGLN
IASQIAHGSPFPANLNGTDFVPAFLTFMEAPRRIGLIGGTRSVVEAAAENFRRHTPWHEFVVVSDGYFDKVDSTEVTEEI
ERQKLDILIVGMGTPLQEKWVHDHIRADHARLVLTVGALFDFVSGAVPRAPRTVRMMRLEWAYRLLQEPTRLWRRYVIGI
PVFLFHVLRYRFRRRERILSHPEEHSTALQPRSEHKKAS

Specific function: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid (Potential) [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=214, Percent_Identity=27.5700934579439, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: =2.4.1.187 [H]

Molecular weight: Translated: 31888; Mature: 31888

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIANFAVLASRRTIFDLPVCDLGWDDALVFINELASIPVGQTVVCFVNAHNMLTALHD
CCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHCC
DEYYRIMSHNLVLPDGIGLNIASQIAHGSPFPANLNGTDFVPAFLTFMEAPRRIGLIGGT
CHHHHHHHCCEECCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHEEECCCH
RSVVEAAAENFRRHTPWHEFVVVSDGYFDKVDSTEVTEEIERQKLDILIVGMGTPLQEKW
HHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHH
VHDHIRADHARLVLTVGALFDFVSGAVPRAPRTVRMMRLEWAYRLLQEPTRLWRRYVIGI
HHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVFLFHVLRYRFRRRERILSHPEEHSTALQPRSEHKKAS
HHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHCCCCC
>Mature Secondary Structure
MNLIANFAVLASRRTIFDLPVCDLGWDDALVFINELASIPVGQTVVCFVNAHNMLTALHD
CCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHCC
DEYYRIMSHNLVLPDGIGLNIASQIAHGSPFPANLNGTDFVPAFLTFMEAPRRIGLIGGT
CHHHHHHHCCEECCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHEEECCCH
RSVVEAAAENFRRHTPWHEFVVVSDGYFDKVDSTEVTEEIERQKLDILIVGMGTPLQEKW
HHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHH
VHDHIRADHARLVLTVGALFDFVSGAVPRAPRTVRMMRLEWAYRLLQEPTRLWRRYVIGI
HHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVFLFHVLRYRFRRRERILSHPEEHSTALQPRSEHKKAS
HHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906926; 9384377; 11882717 [H]