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The map label for this gene is cheA [H]

Identifier: 209547906

GI number: 209547906

Start: 304409

End: 306700

Strand: Direct

Name: cheA [H]

Synonym: Rleg2_0298

Alternate gene names: 209547906

Gene position: 304409-306700 (Clockwise)

Preceding gene: 209547905

Following gene: 209547907

Centisome position: 6.71

GC content: 63.13

Gene sequence:

>2292_bases
ATGGATATGAACGAAATCAAAGAGATCTTTTTCCAGGAGTGCGAGGAACAGCTCGCCGAGCTGGAATCCGGTCTTCTGAA
AATGAATGATGGCGATCGCGATCCGGAAACCGTTAATGCGGTGTTCCGTGCCGTGCATTCGATCAAGGGTGGCGCCGGCG
CCTTCGGCCTTGATGATCTGGTCGCCTTCGCCCATGTTTTCGAGACCACTCTCGATTGCGTTCGATCCAATAAGCTCGAG
CCGACCCAGGATGTCCTGAAGGTGATGCTGAAGTCGGCGGACGTGCTCGCCGACCTGACGAATGCTGCGCGCGACGGCGG
CAGTGTCGATGAAAGCCGCAGCCGCGGTCTCGTCAAGGAGCTGGAGGCGTTGGCCAATGGTGAATTGCCGTCTCCCTCGG
CAGCCGCCGAGGCTCCGGCGCCCAAGGCCGCCGCAAAGCCCGCAGCCGCTGCTCCGGCGCCGGCTCCCAAGCCGACCGAC
GACAGCGGCTTCCAGCCGGTCCCCTTTTCCTTCGACGATTTTGGCGGCGAGGGCGATGCGGGCTCCGGCATGCCGGCCTA
TGAAATCATCTTCAAGCCGCGCTACGAACTCTATTCCAAGGGCAATGACGCCACGCTGCTGCTGCGCGACCTGTCGCGCC
TCGGCGAGATGACCATCTTTTGCAATAGCGATGAGCTGCCGGGCCTCGATGAGCTCGATCCGGAAGGCGCTTATTTCTTC
TGGAACATCACGATCAAGACGGACAAGGGCGAGGACGCCATTCGCACCGTCTTCGAATTCGCCGAATGGGATTGCGAATT
GACGGTGAAGCCGGTCGAGGAAGCAAGGGCTGAGGCGACAAGCAACGACGAACTGCCGATGGTGCCGGTTCCCTTCGATC
TGTCGATCCTGGACGAAGCAGGTGCTGCGGAAGACGTTTCCGGCACTGCCGCCGCCGAGACCGCCGCAGCCGTTGCTGCC
GCCGAGACTGCCTCCAATGTCACGCAGATGGCAGCCGCTGCCGCCCGCGTCGAAAAGAAGGAATCGGCAGCCGCCGCAGC
GGCTGCTGCAAGTGCTGCTGCCGCCCAGAACAATGCCGCCGGCGCCGGCCAGACGATCCGCGTCGATCTCGACCGTGTCG
ACCGCCTGATCAACCTCGTCGGCGAGCTGGTCATCAACCAGGCGATGCTGTCGCAGAGCGTCATCGAAAACGACACGACC
GGCACCTCCTCGATCAACATGGGTCTCGAAGAGCTGCAGCAGCTCACCCGCGAGATCCAGGACTCGGTCATGGCGATCCG
CGCCCAGCCGGTGAAGCCGGTGTTCCAGCGCATGTCGCGTATCGTTCGCGAAATCGCCGACATGACCGGCAAGTCGATCC
GTCTGATCACCGAAGGTGAAAACACCGAAGTCGACAAGACGGTTATCGACAAGCTGGCCGAGCCGCTGACTCACATGATC
CGCAATGCCGTCGACCACGGCATTGAAACGCCGGAAAAGCGCGCCGCCGCCGGCAAGAACACCGAAGGCACGGTTCGCCT
GACCGCCAAGCATCGTTCGGGACGCATCCTGATCGAGCTTGCCGATGACGGCGCCGGCATCAACCGTGAGAAGGTCCGCC
AGAAGGCGATCGACAACGACCTCATCCCGGCCGATTCCAACCTGTCGGACGAGGAAATCGACAACCTGATCTTCCTGCCG
GGCTTCTCGACGGCCGACAAGATCTCCGACATCTCCGGCCGCGGCGTCGGCATGGACGTCGTCAAGCGTTCGATCCAGGC
GCTCGGCGGCCGCATCAACATCACCTCGAAGCCCGGCCACGGCTCGGTCTTCACCATGAGCCTGCCGCTGACGCTCGCCG
TCCTCGACGGCATGGTGGTCACCGTCGCCGGCCAGACGCTGGTCGTGCCGCTGACCGCGATTGTCGAAACCCTGCAGCCG
GAAGCTTCCGCGATCCATTCCTTCGGTGCGAACCACCGGCTGATCTCGATCCGCAACAGCTTCTGCCCGCTGGTCGATGT
CGGCCGCATCCTGAACTTCCGCGCGACCCAGGCCAACCCGGTCGAGGGCGTGGCGCTTCTGGTGGAATCCGAAGGCGGCG
GCCAGCGCGCCCTGATGGTCGATGCCATCCAGGGTCAGCGCCAGGTGGTCATCAAGAGCCTGGAGGCCAACTACACCCAT
GTGCCGGGCATTGCCGCTGCCACCATTCTCGGCGACGGGCGCGTCGCTCTCATTCTCGATGTCGACGCGGTTGTCGGCGC
CTCGCGCGGCCAGTCGCTCAAAGCAGAAATGTCGTTAGCAGCGGTAGGGTAA

Upstream 100 bases:

>100_bases
GCCAGGCTGGCGCCACCGGCTGGATCGTCAAGCCTTTCGACCCGGCCAAGCTGATCGATGCCATTGAGCGTGTAACCGCT
TAAACCCAGGATTTGCTCCT

Downstream 100 bases:

>100_bases
GGGAATGTCGTACGCCGTAAAAAATCTGAACGAGGGGGATCGCGAGCTGATCGCGTTCCGCATCGGGGATCAGGAATTTT
GCGTGAACATCATGTCGGTT

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 763; Mature: 763

Protein sequence:

>763_residues
MDMNEIKEIFFQECEEQLAELESGLLKMNDGDRDPETVNAVFRAVHSIKGGAGAFGLDDLVAFAHVFETTLDCVRSNKLE
PTQDVLKVMLKSADVLADLTNAARDGGSVDESRSRGLVKELEALANGELPSPSAAAEAPAPKAAAKPAAAAPAPAPKPTD
DSGFQPVPFSFDDFGGEGDAGSGMPAYEIIFKPRYELYSKGNDATLLLRDLSRLGEMTIFCNSDELPGLDELDPEGAYFF
WNITIKTDKGEDAIRTVFEFAEWDCELTVKPVEEARAEATSNDELPMVPVPFDLSILDEAGAAEDVSGTAAAETAAAVAA
AETASNVTQMAAAAARVEKKESAAAAAAAASAAAAQNNAAGAGQTIRVDLDRVDRLINLVGELVINQAMLSQSVIENDTT
GTSSINMGLEELQQLTREIQDSVMAIRAQPVKPVFQRMSRIVREIADMTGKSIRLITEGENTEVDKTVIDKLAEPLTHMI
RNAVDHGIETPEKRAAAGKNTEGTVRLTAKHRSGRILIELADDGAGINREKVRQKAIDNDLIPADSNLSDEEIDNLIFLP
GFSTADKISDISGRGVGMDVVKRSIQALGGRINITSKPGHGSVFTMSLPLTLAVLDGMVVTVAGQTLVVPLTAIVETLQP
EASAIHSFGANHRLISIRNSFCPLVDVGRILNFRATQANPVEGVALLVESEGGGQRALMVDAIQGQRQVVIKSLEANYTH
VPGIAAATILGDGRVALILDVDAVVGASRGQSLKAEMSLAAVG

Sequences:

>Translated_763_residues
MDMNEIKEIFFQECEEQLAELESGLLKMNDGDRDPETVNAVFRAVHSIKGGAGAFGLDDLVAFAHVFETTLDCVRSNKLE
PTQDVLKVMLKSADVLADLTNAARDGGSVDESRSRGLVKELEALANGELPSPSAAAEAPAPKAAAKPAAAAPAPAPKPTD
DSGFQPVPFSFDDFGGEGDAGSGMPAYEIIFKPRYELYSKGNDATLLLRDLSRLGEMTIFCNSDELPGLDELDPEGAYFF
WNITIKTDKGEDAIRTVFEFAEWDCELTVKPVEEARAEATSNDELPMVPVPFDLSILDEAGAAEDVSGTAAAETAAAVAA
AETASNVTQMAAAAARVEKKESAAAAAAAASAAAAQNNAAGAGQTIRVDLDRVDRLINLVGELVINQAMLSQSVIENDTT
GTSSINMGLEELQQLTREIQDSVMAIRAQPVKPVFQRMSRIVREIADMTGKSIRLITEGENTEVDKTVIDKLAEPLTHMI
RNAVDHGIETPEKRAAAGKNTEGTVRLTAKHRSGRILIELADDGAGINREKVRQKAIDNDLIPADSNLSDEEIDNLIFLP
GFSTADKISDISGRGVGMDVVKRSIQALGGRINITSKPGHGSVFTMSLPLTLAVLDGMVVTVAGQTLVVPLTAIVETLQP
EASAIHSFGANHRLISIRNSFCPLVDVGRILNFRATQANPVEGVALLVESEGGGQRALMVDAIQGQRQVVIKSLEANYTH
VPGIAAATILGDGRVALILDVDAVVGASRGQSLKAEMSLAAVG
>Mature_763_residues
MDMNEIKEIFFQECEEQLAELESGLLKMNDGDRDPETVNAVFRAVHSIKGGAGAFGLDDLVAFAHVFETTLDCVRSNKLE
PTQDVLKVMLKSADVLADLTNAARDGGSVDESRSRGLVKELEALANGELPSPSAAAEAPAPKAAAKPAAAAPAPAPKPTD
DSGFQPVPFSFDDFGGEGDAGSGMPAYEIIFKPRYELYSKGNDATLLLRDLSRLGEMTIFCNSDELPGLDELDPEGAYFF
WNITIKTDKGEDAIRTVFEFAEWDCELTVKPVEEARAEATSNDELPMVPVPFDLSILDEAGAAEDVSGTAAAETAAAVAA
AETASNVTQMAAAAARVEKKESAAAAAAAASAAAAQNNAAGAGQTIRVDLDRVDRLINLVGELVINQAMLSQSVIENDTT
GTSSINMGLEELQQLTREIQDSVMAIRAQPVKPVFQRMSRIVREIADMTGKSIRLITEGENTEVDKTVIDKLAEPLTHMI
RNAVDHGIETPEKRAAAGKNTEGTVRLTAKHRSGRILIELADDGAGINREKVRQKAIDNDLIPADSNLSDEEIDNLIFLP
GFSTADKISDISGRGVGMDVVKRSIQALGGRINITSKPGHGSVFTMSLPLTLAVLDGMVVTVAGQTLVVPLTAIVETLQP
EASAIHSFGANHRLISIRNSFCPLVDVGRILNFRATQANPVEGVALLVESEGGGQRALMVDAIQGQRQVVIKSLEANYTH
VPGIAAATILGDGRVALILDVDAVVGASRGQSLKAEMSLAAVG

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=411, Percent_Identity=45.985401459854, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80783; Mature: 80783

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMNEIKEIFFQECEEQLAELESGLLKMNDGDRDPETVNAVFRAVHSIKGGAGAFGLDDL
CCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHH
VAFAHVFETTLDCVRSNKLEPTQDVLKVMLKSADVLADLTNAARDGGSVDESRSRGLVKE
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHH
LEALANGELPSPSAAAEAPAPKAAAKPAAAAPAPAPKPTDDSGFQPVPFSFDDFGGEGDA
HHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GSGMPAYEIIFKPRYELYSKGNDATLLLRDLSRLGEMTIFCNSDELPGLDELDPEGAYFF
CCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCEEE
WNITIKTDKGEDAIRTVFEFAEWDCELTVKPVEEARAEATSNDELPMVPVPFDLSILDEA
EEEEEEECCCCHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCCCEEECCCCHHHHCCC
GAAEDVSGTAAAETAAAVAAAETASNVTQMAAAAARVEKKESAAAAAAAASAAAAQNNAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAGQTIRVDLDRVDRLINLVGELVINQAMLSQSVIENDTTGTSSINMGLEELQQLTREIQ
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
DSVMAIRAQPVKPVFQRMSRIVREIADMTGKSIRLITEGENTEVDKTVIDKLAEPLTHMI
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
RNAVDHGIETPEKRAAAGKNTEGTVRLTAKHRSGRILIELADDGAGINREKVRQKAIDND
HHHHHCCCCCCHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCC
LIPADSNLSDEEIDNLIFLPGFSTADKISDISGRGVGMDVVKRSIQALGGRINITSKPGH
CCCCCCCCCHHHHCCEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCC
GSVFTMSLPLTLAVLDGMVVTVAGQTLVVPLTAIVETLQPEASAIHSFGANHRLISIRNS
CCEEEEECCHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCC
FCPLVDVGRILNFRATQANPVEGVALLVESEGGGQRALMVDAIQGQRQVVIKSLEANYTH
CCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHCCCCCC
VPGIAAATILGDGRVALILDVDAVVGASRGQSLKAEMSLAAVG
CCCHHEEEEECCCCEEEEEECHHHHCCCCCCCCCHHCEEEECC
>Mature Secondary Structure
MDMNEIKEIFFQECEEQLAELESGLLKMNDGDRDPETVNAVFRAVHSIKGGAGAFGLDDL
CCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHH
VAFAHVFETTLDCVRSNKLEPTQDVLKVMLKSADVLADLTNAARDGGSVDESRSRGLVKE
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHH
LEALANGELPSPSAAAEAPAPKAAAKPAAAAPAPAPKPTDDSGFQPVPFSFDDFGGEGDA
HHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GSGMPAYEIIFKPRYELYSKGNDATLLLRDLSRLGEMTIFCNSDELPGLDELDPEGAYFF
CCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCEEE
WNITIKTDKGEDAIRTVFEFAEWDCELTVKPVEEARAEATSNDELPMVPVPFDLSILDEA
EEEEEEECCCCHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCCCEEECCCCHHHHCCC
GAAEDVSGTAAAETAAAVAAAETASNVTQMAAAAARVEKKESAAAAAAAASAAAAQNNAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAGQTIRVDLDRVDRLINLVGELVINQAMLSQSVIENDTTGTSSINMGLEELQQLTREIQ
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
DSVMAIRAQPVKPVFQRMSRIVREIADMTGKSIRLITEGENTEVDKTVIDKLAEPLTHMI
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
RNAVDHGIETPEKRAAAGKNTEGTVRLTAKHRSGRILIELADDGAGINREKVRQKAIDND
HHHHHCCCCCCHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCC
LIPADSNLSDEEIDNLIFLPGFSTADKISDISGRGVGMDVVKRSIQALGGRINITSKPGH
CCCCCCCCCHHHHCCEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCC
GSVFTMSLPLTLAVLDGMVVTVAGQTLVVPLTAIVETLQPEASAIHSFGANHRLISIRNS
CCEEEEECCHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCC
FCPLVDVGRILNFRATQANPVEGVALLVESEGGGQRALMVDAIQGQRQVVIKSLEANYTH
CCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHCCCCCC
VPGIAAATILGDGRVALILDVDAVVGASRGQSLKAEMSLAAVG
CCCHHEEEEECCCCEEEEEECHHHHCCCCCCCCCHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]