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The map label for this gene is mcpE [H]

Identifier: 209547903

GI number: 209547903

Start: 302041

End: 303669

Strand: Direct

Name: mcpE [H]

Synonym: Rleg2_0295

Alternate gene names: 209547903

Gene position: 302041-303669 (Clockwise)

Preceding gene: 209547901

Following gene: 209547904

Centisome position: 6.66

GC content: 67.65

Gene sequence:

>1629_bases
ATGCCATCAGATCAGGCTCGTGGAGCGCAGGCAGGCAGCTTGCGCGACCGCCTGCGCTTTGCCGGCCTCGATGCCGACCA
GTGCGAACTGGTGCGCCGCAACCGGCCGGCCCTCGAAGCGCATCTGAAGGCAGGCCTGCGCGATCTCTTCCACAGGTTCC
AGTCATTCCCCGACGCCGCCCGCAATTTCGACAGCGAGCGCCAGGTCGAGCGCCTGCATGATCTGCAGTCCTCGCATTGG
GACGTGCTGACGGATGCCCGGTTCGACAGCCTCTATGCCGAACGCGTCAAGGTTCTCTCCGATACCGAAAGCAAGATCGG
CCTTGATCCGCGCTGGCACGTCGCCGGCCACGGCGTCATGCTGGAGCATGTCGTTGCCGGTCTCGCCGAGGAAATTGCCG
GCCGTCCGCTGCTGCCGTCGGCCAAGCGCCGCACCCGCGAAATCTCCGATCTGATGACGGCGATCATCCGCCTCGTCATG
GTCGATGTGGAAATCGCCGTCTCGCTGCGCTTCAACGCCCAGCGCGCCGCCCAGAGCCGTGCGCTCGCCGATCAGCGTAC
CGACAACGAGGCCGAGATCGTCAGGATCTTCGGCGATGTAATCGAAGGCCTTTCCGCCCGCGACCTGACGCGGCGCGCCC
CCGTCGACGGCGCCCATGCGGCGACTGCCGCCGCGCTGAACGGCGCCTTGGATGGCCTCCAGGTAGAGTTTGCTGCCATC
ACCGAACGCACGCTGAAGGCCGAAGCGGCGACCGGGTCGCTTGCCGGCCTGTCCAGGCAGTTCGCTGGCACGGCGTCGGG
CCAGGCCGACCGGCTGCAGCTTTCCGCCGCCGCGCTTGCCGGCATCGCCGCCAGCGTTCGCGATGGCGCTGCCGACAGCC
GCGCCGCCGAGCAGGCCGTCGCCTCGACGCGCGCCGCCGTCGAGGAAAGCGGTGAGGTCGTCGGCCGCGCGATCAGCGCC
ATGGCCGATATCGAGCAGTCGGCCGAAAAGATCGGCCAGATCATCGGCACGATCGACGAGATCGCCTTCCAGACCAATCT
GCTGGCGCTGAATGCCGGCATCGAGGCCGCTCGCGCCGGCGATTCCGGCCGCGGTTTTGCCGTTGTCGCCCAGGAGGTCC
GCGCGCTCGCCCAGCGTTCGGCCGAGGCCGCCCGCGAGATCAAGACGCTGGTGACGACCACCAAGGCGCAGGTCGATGCC
GGGGTGCAGATGGTCGGCCGCACACAGGATTCGATCGGCAGCATCGTGCGCCAGGTCACCGACATCAATGCCGCCATATC
GGGCATCGCCACCCGCACCGGCGAACATGCATCAAGCCTCGATAGCGTGACTTCCGACGTCAAGGGCCTGGGCGGCGAAG
TGGCAGGCAGCGCCGGCCTTGCGGAGCGCTCGGCCGAAGGCGCCGACCACCTCCATACGGTCATTGTCGAGCTCGGCCAG
ACGATTCGCGAATTCCGCATCGCCCGGGAAAACGTCAATGCCGGGCGCCCGGCGCCGGTTCGCGTGACGCCGCCGCGCGC
CATCGAAGCCGCCGCCCGTCCGGCTGTGGCCGAGGACGAATACGAAAATGATGATTTTAGCCTTCCGCAGCCCTTCGCAA
GCGTCGGAGGTGGGCGGAATGTTTACTAA

Upstream 100 bases:

>100_bases
GAGAACCGTCTCGAGGCTTTGCGTTTCTCTGGATGCTGCGAAAGTTTTTAACCAGGCATTCGCCTGGACAGTGGGTCGGG
GACAGGCGTTGAGGCAGGAC

Downstream 100 bases:

>100_bases
CCTATCGGATGATTGCCGCAGCTCGTCTTCTCGAGCCGGGGACAAGGGGACAAGGAAAAGCTGATGGTAGCAAAGAAGAG
TGGCAAGACGCTGGATCTGA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MPSDQARGAQAGSLRDRLRFAGLDADQCELVRRNRPALEAHLKAGLRDLFHRFQSFPDAARNFDSERQVERLHDLQSSHW
DVLTDARFDSLYAERVKVLSDTESKIGLDPRWHVAGHGVMLEHVVAGLAEEIAGRPLLPSAKRRTREISDLMTAIIRLVM
VDVEIAVSLRFNAQRAAQSRALADQRTDNEAEIVRIFGDVIEGLSARDLTRRAPVDGAHAATAAALNGALDGLQVEFAAI
TERTLKAEAATGSLAGLSRQFAGTASGQADRLQLSAAALAGIAASVRDGAADSRAAEQAVASTRAAVEESGEVVGRAISA
MADIEQSAEKIGQIIGTIDEIAFQTNLLALNAGIEAARAGDSGRGFAVVAQEVRALAQRSAEAAREIKTLVTTTKAQVDA
GVQMVGRTQDSIGSIVRQVTDINAAISGIATRTGEHASSLDSVTSDVKGLGGEVAGSAGLAERSAEGADHLHTVIVELGQ
TIREFRIARENVNAGRPAPVRVTPPRAIEAAARPAVAEDEYENDDFSLPQPFASVGGGRNVY

Sequences:

>Translated_542_residues
MPSDQARGAQAGSLRDRLRFAGLDADQCELVRRNRPALEAHLKAGLRDLFHRFQSFPDAARNFDSERQVERLHDLQSSHW
DVLTDARFDSLYAERVKVLSDTESKIGLDPRWHVAGHGVMLEHVVAGLAEEIAGRPLLPSAKRRTREISDLMTAIIRLVM
VDVEIAVSLRFNAQRAAQSRALADQRTDNEAEIVRIFGDVIEGLSARDLTRRAPVDGAHAATAAALNGALDGLQVEFAAI
TERTLKAEAATGSLAGLSRQFAGTASGQADRLQLSAAALAGIAASVRDGAADSRAAEQAVASTRAAVEESGEVVGRAISA
MADIEQSAEKIGQIIGTIDEIAFQTNLLALNAGIEAARAGDSGRGFAVVAQEVRALAQRSAEAAREIKTLVTTTKAQVDA
GVQMVGRTQDSIGSIVRQVTDINAAISGIATRTGEHASSLDSVTSDVKGLGGEVAGSAGLAERSAEGADHLHTVIVELGQ
TIREFRIARENVNAGRPAPVRVTPPRAIEAAARPAVAEDEYENDDFSLPQPFASVGGGRNVY
>Mature_541_residues
PSDQARGAQAGSLRDRLRFAGLDADQCELVRRNRPALEAHLKAGLRDLFHRFQSFPDAARNFDSERQVERLHDLQSSHWD
VLTDARFDSLYAERVKVLSDTESKIGLDPRWHVAGHGVMLEHVVAGLAEEIAGRPLLPSAKRRTREISDLMTAIIRLVMV
DVEIAVSLRFNAQRAAQSRALADQRTDNEAEIVRIFGDVIEGLSARDLTRRAPVDGAHAATAAALNGALDGLQVEFAAIT
ERTLKAEAATGSLAGLSRQFAGTASGQADRLQLSAAALAGIAASVRDGAADSRAAEQAVASTRAAVEESGEVVGRAISAM
ADIEQSAEKIGQIIGTIDEIAFQTNLLALNAGIEAARAGDSGRGFAVVAQEVRALAQRSAEAAREIKTLVTTTKAQVDAG
VQMVGRTQDSIGSIVRQVTDINAAISGIATRTGEHASSLDSVTSDVKGLGGEVAGSAGLAERSAEGADHLHTVIVELGQT
IREFRIARENVNAGRPAPVRVTPPRAIEAAARPAVAEDEYENDDFSLPQPFASVGGGRNVY

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=176, Percent_Identity=44.3181818181818, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788195, Length=247, Percent_Identity=37.6518218623482, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1789453, Length=198, Percent_Identity=41.9191919191919, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI1788194, Length=240, Percent_Identity=37.0833333333333, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1787690, Length=227, Percent_Identity=33.0396475770925, Blast_Score=116, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR012292
- InterPro:   IPR009050 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57411; Mature: 57280

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSDQARGAQAGSLRDRLRFAGLDADQCELVRRNRPALEAHLKAGLRDLFHRFQSFPDAA
CCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHH
RNFDSERQVERLHDLQSSHWDVLTDARFDSLYAERVKVLSDTESKIGLDPRWHVAGHGVM
HCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEECCCCHH
LEHVVAGLAEEIAGRPLLPSAKRRTREISDLMTAIIRLVMVDVEIAVSLRFNAQRAAQSR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHHHHHH
ALADQRTDNEAEIVRIFGDVIEGLSARDLTRRAPVDGAHAATAAALNGALDGLQVEFAAI
HHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEHHHHH
TERTLKAEAATGSLAGLSRQFAGTASGQADRLQLSAAALAGIAASVRDGAADSRAAEQAV
HHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ASTRAAVEESGEVVGRAISAMADIEQSAEKIGQIIGTIDEIAFQTNLLALNAGIEAARAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHCCC
DSGRGFAVVAQEVRALAQRSAEAAREIKTLVTTTKAQVDAGVQMVGRTQDSIGSIVRQVT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DINAAISGIATRTGEHASSLDSVTSDVKGLGGEVAGSAGLAERSAEGADHLHTVIVELGQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHH
TIREFRIARENVNAGRPAPVRVTPPRAIEAAARPAVAEDEYENDDFSLPQPFASVGGGRN
HHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCC
VY
CC
>Mature Secondary Structure 
PSDQARGAQAGSLRDRLRFAGLDADQCELVRRNRPALEAHLKAGLRDLFHRFQSFPDAA
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHH
RNFDSERQVERLHDLQSSHWDVLTDARFDSLYAERVKVLSDTESKIGLDPRWHVAGHGVM
HCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEECCCCHH
LEHVVAGLAEEIAGRPLLPSAKRRTREISDLMTAIIRLVMVDVEIAVSLRFNAQRAAQSR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHHHHHH
ALADQRTDNEAEIVRIFGDVIEGLSARDLTRRAPVDGAHAATAAALNGALDGLQVEFAAI
HHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEHHHHH
TERTLKAEAATGSLAGLSRQFAGTASGQADRLQLSAAALAGIAASVRDGAADSRAAEQAV
HHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ASTRAAVEESGEVVGRAISAMADIEQSAEKIGQIIGTIDEIAFQTNLLALNAGIEAARAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHCCC
DSGRGFAVVAQEVRALAQRSAEAAREIKTLVTTTKAQVDAGVQMVGRTQDSIGSIVRQVT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DINAAISGIATRTGEHASSLDSVTSDVKGLGGEVAGSAGLAERSAEGADHLHTVIVELGQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHH
TIREFRIARENVNAGRPAPVRVTPPRAIEAAARPAVAEDEYENDDFSLPQPFASVGGGRN
HHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCC
VY
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]