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The map label for this gene is cph1 [H]

Identifier: 209547891

GI number: 209547891

Start: 287470

End: 289065

Strand: Reverse

Name: cph1 [H]

Synonym: Rleg2_0283

Alternate gene names: 209547891

Gene position: 289065-287470 (Counterclockwise)

Preceding gene: 209547892

Following gene: 209547890

Centisome position: 6.37

GC content: 62.78

Gene sequence:

>1596_bases
TTGGCGGAAGAGTGCAGCATTCTCATCATCGACGACAATATTGACGATCGCGAGGTCTATCGCCGCATATTGGGCCGCGT
CTCCAGCACCGCCTATAGCGTCCTGGAGGCGGAGACAGGCGAAGAGGGCCTTGCGCTGAACGGCCGCAAACGGCCGAACT
GCATCCTGCTCGACTATTCGCTGCCGGGTCGCAACGGGCTCGGCGTTCTGGCCGATATTCTGGAGAACGATCCCGCCGCC
AACGTCATCATGCTGACCGGCCAGGGCAGCGAGACCGTCGCCGTCGAGGTGATGAAGAGTGGCGCGCGCGACTATCTGAC
GAAGGATTCGCTGTCGCCCGAAACCCTGCATCGCTGCATCCAGAACGCCATCATGCACGGCATGCTGGAAGCGCAGCTGG
AGCAGAAGCGGCAATCGCTCGAGATCTTCACACGCGCCATGGCCCATGATCTGAAGGAGCCGCTCAGGACGATCAAATCC
TTCAGCCGCATCCTGCATGGTTCTGCAGCGCTTCCGGCCGACGACCGGGAACTGCTCGATTATGTGCTGAGTGCCGCCGA
CCATATGGAAGACCTGATCGTCAAGGTTTCCGGTTTCACCAGGCTGGAAGCCTCCGGTGGGCCGGAGCTCAAGCCGGTTT
CGCTCTCTGCCGTACTCGACCAGGTGGAGGACAATCTGCGCCAGCAGACCGAAAGCCGCGGCGCGATGATCATCCGCGGC
GCGCTGCCGGAGGTCATGGGCGATGCGACGCTGCTGACCCAACTGTTGCAGAACCTCGTGTCGAATGCCATCCGCTATTG
CGAGCAGAAGGTTCCGGAGGTCACGATCTCAGGCGAAGCCCATGGCGATTTCTGCCGCCTCACCGTGCGCGACAACGGGC
CCGGCATCGATCCTCAGCATCGCGAACTGATCTTCCAGCCGTTCAAACGCCTCGTCGGCCGCGGCATCGAGGGCACCGGG
CTCGGCCTTGCCATCTGCCGCCGCATCGCGCAGCTGCATGGCGGCTCGATCTGGTGCGAGGCGGAGGATGGCCCGGGCGC
CACTTTCGTTCTCGACGTGCCGCTCGCCGAGACGAGGCCCGAGCCGCCCGCTGCAGCGGCCATCCCGCACAGCGGCAAGC
CGGCGGAGCAGCCGGGCGAAGGCGAAGGCAGGCTTGCCGAAGTGCTGTTGGTGGAGGACAGCCCGGCCGATATCCAGCTT
CTGAAGATCAAGCTGATGCGGCGGGAGAAGGTGAATTTCAACCTGCATGTCGCCACCAACGGCCGCGAGGCGATGCGGCT
GCTCGAGGAACGCGCCGGTATTGCCGAGGTGCCGCAGATCGACCTGATGCTGCTCGATATCAATATGCCGATCATGGACG
GCTTCGAGGTACTGCGTGCGCTTTCCACCGATGTCCGCCTCAACCAGATTCCCGTCTGCATTCTCAGCACCTCAAGCGAT
GAGACCGACCGGCAGCGGGCCAGAAATCTCGGTGCGCGCGCCTATATGGTCAAGCCGCCGACCCTGCAGCAACTCGAAGA
GGCGCTCGAATATGTCGATCATCTGGAATTGCTGCAGCGCGGCGATTCGCTTGCGCTTTGTGCGGAACAAAACTAA

Upstream 100 bases:

>100_bases
GTGCAGAAGCCGGTCGATCTCGACGGGCTGTTTGCGGCGATCCAGCGGCTGAAGGAATACTGGTTCGAAATCGCCATCCT
GCCGCTCGAGGACTGACAGA

Downstream 100 bases:

>100_bases
GCGATGGTCATTGGCAACGGTATGACCTTCGCAGCTTTCATACTCGCGCTCCTGACGACACCGCTTCAATCAGGACTGCT
TCCGATGGTATCAGGCATAC

Product: response regulator receiver sensor hybrid histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MAEECSILIIDDNIDDREVYRRILGRVSSTAYSVLEAETGEEGLALNGRKRPNCILLDYSLPGRNGLGVLADILENDPAA
NVIMLTGQGSETVAVEVMKSGARDYLTKDSLSPETLHRCIQNAIMHGMLEAQLEQKRQSLEIFTRAMAHDLKEPLRTIKS
FSRILHGSAALPADDRELLDYVLSAADHMEDLIVKVSGFTRLEASGGPELKPVSLSAVLDQVEDNLRQQTESRGAMIIRG
ALPEVMGDATLLTQLLQNLVSNAIRYCEQKVPEVTISGEAHGDFCRLTVRDNGPGIDPQHRELIFQPFKRLVGRGIEGTG
LGLAICRRIAQLHGGSIWCEAEDGPGATFVLDVPLAETRPEPPAAAAIPHSGKPAEQPGEGEGRLAEVLLVEDSPADIQL
LKIKLMRREKVNFNLHVATNGREAMRLLEERAGIAEVPQIDLMLLDINMPIMDGFEVLRALSTDVRLNQIPVCILSTSSD
ETDRQRARNLGARAYMVKPPTLQQLEEALEYVDHLELLQRGDSLALCAEQN

Sequences:

>Translated_531_residues
MAEECSILIIDDNIDDREVYRRILGRVSSTAYSVLEAETGEEGLALNGRKRPNCILLDYSLPGRNGLGVLADILENDPAA
NVIMLTGQGSETVAVEVMKSGARDYLTKDSLSPETLHRCIQNAIMHGMLEAQLEQKRQSLEIFTRAMAHDLKEPLRTIKS
FSRILHGSAALPADDRELLDYVLSAADHMEDLIVKVSGFTRLEASGGPELKPVSLSAVLDQVEDNLRQQTESRGAMIIRG
ALPEVMGDATLLTQLLQNLVSNAIRYCEQKVPEVTISGEAHGDFCRLTVRDNGPGIDPQHRELIFQPFKRLVGRGIEGTG
LGLAICRRIAQLHGGSIWCEAEDGPGATFVLDVPLAETRPEPPAAAAIPHSGKPAEQPGEGEGRLAEVLLVEDSPADIQL
LKIKLMRREKVNFNLHVATNGREAMRLLEERAGIAEVPQIDLMLLDINMPIMDGFEVLRALSTDVRLNQIPVCILSTSSD
ETDRQRARNLGARAYMVKPPTLQQLEEALEYVDHLELLQRGDSLALCAEQN
>Mature_530_residues
AEECSILIIDDNIDDREVYRRILGRVSSTAYSVLEAETGEEGLALNGRKRPNCILLDYSLPGRNGLGVLADILENDPAAN
VIMLTGQGSETVAVEVMKSGARDYLTKDSLSPETLHRCIQNAIMHGMLEAQLEQKRQSLEIFTRAMAHDLKEPLRTIKSF
SRILHGSAALPADDRELLDYVLSAADHMEDLIVKVSGFTRLEASGGPELKPVSLSAVLDQVEDNLRQQTESRGAMIIRGA
LPEVMGDATLLTQLLQNLVSNAIRYCEQKVPEVTISGEAHGDFCRLTVRDNGPGIDPQHRELIFQPFKRLVGRGIEGTGL
GLAICRRIAQLHGGSIWCEAEDGPGATFVLDVPLAETRPEPPAAAAIPHSGKPAEQPGEGEGRLAEVLLVEDSPADIQLL
KIKLMRREKVNFNLHVATNGREAMRLLEERAGIAEVPQIDLMLLDINMPIMDGFEVLRALSTDVRLNQIPVCILSTSSDE
TDRQRARNLGARAYMVKPPTLQQLEEALEYVDHLELLQRGDSLALCAEQN

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=376, Percent_Identity=27.3936170212766, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788713, Length=378, Percent_Identity=24.0740740740741, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI87081816, Length=394, Percent_Identity=28.6802030456853, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=28.8135593220339, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787894, Length=246, Percent_Identity=30.8943089430894, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=264, Percent_Identity=31.4393939393939, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789149, Length=224, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI145693157, Length=231, Percent_Identity=28.1385281385281, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1788549, Length=286, Percent_Identity=28.3216783216783, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790346, Length=219, Percent_Identity=30.1369863013699, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=264, Percent_Identity=26.5151515151515, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790300, Length=234, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=24.1379310344828, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790551, Length=261, Percent_Identity=30.2681992337165, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786783, Length=220, Percent_Identity=26.3636363636364, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789403, Length=210, Percent_Identity=30, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=248, Percent_Identity=26.2096774193548, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=25.6521739130435, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1790861, Length=214, Percent_Identity=28.9719626168224, Blast_Score=62, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=74, Percent_Identity=41.8918918918919, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58300; Mature: 58168

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEECSILIIDDNIDDREVYRRILGRVSSTAYSVLEAETGEEGLALNGRKRPNCILLDYS
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEEEEEEC
LPGRNGLGVLADILENDPAANVIMLTGQGSETVAVEVMKSGARDYLTKDSLSPETLHRCI
CCCCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHCCCCCCHHHHHHHH
QNAIMHGMLEAQLEQKRQSLEIFTRAMAHDLKEPLRTIKSFSRILHGSAALPADDRELLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
YVLSAADHMEDLIVKVSGFTRLEASGGPELKPVSLSAVLDQVEDNLRQQTESRGAMIIRG
HHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEC
ALPEVMGDATLLTQLLQNLVSNAIRYCEQKVPEVTISGEAHGDFCRLTVRDNGPGIDPQH
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCCCCCCHHH
RELIFQPFKRLVGRGIEGTGLGLAICRRIAQLHGGSIWCEAEDGPGATFVLDVPLAETRP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCCC
EPPAAAAIPHSGKPAEQPGEGEGRLAEVLLVEDSPADIQLLKIKLMRREKVNFNLHVATN
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEHHHHHHHHHHCCCEEEEEECC
GREAMRLLEERAGIAEVPQIDLMLLDINMPIMDGFEVLRALSTDVRLNQIPVCILSTSSD
CHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCEECCCCEEEEECCCC
ETDRQRARNLGARAYMVKPPTLQQLEEALEYVDHLELLQRGDSLALCAEQN
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure 
AEECSILIIDDNIDDREVYRRILGRVSSTAYSVLEAETGEEGLALNGRKRPNCILLDYS
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEEEEEEC
LPGRNGLGVLADILENDPAANVIMLTGQGSETVAVEVMKSGARDYLTKDSLSPETLHRCI
CCCCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHCCCCCCHHHHHHHH
QNAIMHGMLEAQLEQKRQSLEIFTRAMAHDLKEPLRTIKSFSRILHGSAALPADDRELLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
YVLSAADHMEDLIVKVSGFTRLEASGGPELKPVSLSAVLDQVEDNLRQQTESRGAMIIRG
HHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEC
ALPEVMGDATLLTQLLQNLVSNAIRYCEQKVPEVTISGEAHGDFCRLTVRDNGPGIDPQH
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCCCCCCHHH
RELIFQPFKRLVGRGIEGTGLGLAICRRIAQLHGGSIWCEAEDGPGATFVLDVPLAETRP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCCC
EPPAAAAIPHSGKPAEQPGEGEGRLAEVLLVEDSPADIQLLKIKLMRREKVNFNLHVATN
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEHHHHHHHHHHCCCEEEEEECC
GREAMRLLEERAGIAEVPQIDLMLLDINMPIMDGFEVLRALSTDVRLNQIPVCILSTSSD
CHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCEECCCCEEEEECCCC
ETDRQRARNLGARAYMVKPPTLQQLEEALEYVDHLELLQRGDSLALCAEQN
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]