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The map label for this gene is murA [H]

Identifier: 209547846

GI number: 209547846

Start: 242789

End: 244081

Strand: Direct

Name: murA [H]

Synonym: Rleg2_0237

Alternate gene names: 209547846

Gene position: 242789-244081 (Clockwise)

Preceding gene: 209547845

Following gene: 209547847

Centisome position: 5.35

GC content: 64.81

Gene sequence:

>1293_bases
ATGGATCGTATCAGAATCGTCGGCGGTAATGAGCTGAATGGCATCATTCCGATTTCCGGCGCCAAGAATGCCGCATTGCC
GCTGATGATTGCCTCGCTTCTGACCAGCGATACGCTGACGCTCGAAAACGTCCCGCATCTGGCCGATGTCGAACTCTTGA
TGCGCATCCTCGGCAATCATGGCGTTGACGTTGCGGTCAACGGCCGCCGCGAGCGCCAGGAGGATTCCTATTCGCGCACG
ATCCATTTCACCTGCCGCACCATCGTCGATACCACCGCTTCCTATGAGCTGGTCTCGAAGATGCGCGCCTCTTTCTGGGT
CATCGGCCCGCTGCTGGCGCGCGAAGGCCATTGCCGGGTGTCGCTGCCGGGCGGCTGCGCCATCGGCACGCGCCCCGTCG
ATCTCTTCATCGAGGGACTGACGGCGCTCGGCGCCACCATGGAGATCGATGCCGGTTATATCAACGCCAAGGCGCCGAAT
GGCGGCCTGATCGGCGCGCGCTACACCTTCCCGAAGGTTTCGGTCGGCGCCACCCATGTGGTGATGATGGCGGCAACCCT
TGCCCGCGGCACGACTGTCATTGGCAATGCCGCCCGCGAGCCTGAAGTCGTCGACCTTGCCAACTGCCTGAACGCCATGG
GCGCCAAGATCTCCGGCGCCGGCACCGCGACGATCACCATCGAGGGCGTCACCTCGCTCTCCGGTGCCCGCCACCGCGTC
CTGCCGGATCGCATCGAGACCGGCACCTACGCCATGGCAGTTGCCATGGCCGGCGGCGACGTCGTGCTCGAAAATACCGA
TGTGGCGTTGCTCGACACCGCATTGGAAACGCTGCGCCGCGCCGGTGCCGACATCTCCGCGACCAACAACGGCATGCGCG
TCAAGCGCAATGGCGCCGGCATCAAGCCGGTCGATATCGTCACCGATCCCTTCCCGGGTTTCCCCACCGATCTGCAGGCG
CAGTTCATGGCGCTGATGACCCGCTCTTCCGGCATCTCGCACGTCACCGAGACCATCTTCGAAAACCGCTTCATGCATGT
GCAGGAACTGGCTCGCCTCGGCGCCAGGATCACGCTCTCCGGCCAGACGGCGAAGATCGAGGGTGTCCAGCGGCTGCGCG
GCGCCCCCGTCATGGCGACCGATCTGCGTGCCTCCGTCTCGCTCGTCATCGCCGGCCTGGCCGCCGAAGGCGAAACCACG
GTCTCCCGCGTCTATCACCTCGACCGCGGTTTCGAGCGGCTCGAGGAGAAGCTGACCCGCTGCGGCGCCGTCGTCGAGCG
CATCAGCGAGTAA

Upstream 100 bases:

>100_bases
GTCCGCGGTCAATTGAAGCGTCGCGAAAAATCCCTTAAACACCCCACTCCCTATTCCAAGGCAGTATTTCAGGAAAGGCG
GGCGCGGCCCGTAAGCGCAC

Downstream 100 bases:

>100_bases
GCCGTTCATCCCGGTTGCGTATTTGGCCGCAGCATCTTATTTCCCTTGTCTGACGCATCGCCATTTCGGCGGTGCCTGCT
GGGATAAAGCTGAATGACCG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MDRIRIVGGNELNGIIPISGAKNAALPLMIASLLTSDTLTLENVPHLADVELLMRILGNHGVDVAVNGRRERQEDSYSRT
IHFTCRTIVDTTASYELVSKMRASFWVIGPLLAREGHCRVSLPGGCAIGTRPVDLFIEGLTALGATMEIDAGYINAKAPN
GGLIGARYTFPKVSVGATHVVMMAATLARGTTVIGNAAREPEVVDLANCLNAMGAKISGAGTATITIEGVTSLSGARHRV
LPDRIETGTYAMAVAMAGGDVVLENTDVALLDTALETLRRAGADISATNNGMRVKRNGAGIKPVDIVTDPFPGFPTDLQA
QFMALMTRSSGISHVTETIFENRFMHVQELARLGARITLSGQTAKIEGVQRLRGAPVMATDLRASVSLVIAGLAAEGETT
VSRVYHLDRGFERLEEKLTRCGAVVERISE

Sequences:

>Translated_430_residues
MDRIRIVGGNELNGIIPISGAKNAALPLMIASLLTSDTLTLENVPHLADVELLMRILGNHGVDVAVNGRRERQEDSYSRT
IHFTCRTIVDTTASYELVSKMRASFWVIGPLLAREGHCRVSLPGGCAIGTRPVDLFIEGLTALGATMEIDAGYINAKAPN
GGLIGARYTFPKVSVGATHVVMMAATLARGTTVIGNAAREPEVVDLANCLNAMGAKISGAGTATITIEGVTSLSGARHRV
LPDRIETGTYAMAVAMAGGDVVLENTDVALLDTALETLRRAGADISATNNGMRVKRNGAGIKPVDIVTDPFPGFPTDLQA
QFMALMTRSSGISHVTETIFENRFMHVQELARLGARITLSGQTAKIEGVQRLRGAPVMATDLRASVSLVIAGLAAEGETT
VSRVYHLDRGFERLEEKLTRCGAVVERISE
>Mature_430_residues
MDRIRIVGGNELNGIIPISGAKNAALPLMIASLLTSDTLTLENVPHLADVELLMRILGNHGVDVAVNGRRERQEDSYSRT
IHFTCRTIVDTTASYELVSKMRASFWVIGPLLAREGHCRVSLPGGCAIGTRPVDLFIEGLTALGATMEIDAGYINAKAPN
GGLIGARYTFPKVSVGATHVVMMAATLARGTTVIGNAAREPEVVDLANCLNAMGAKISGAGTATITIEGVTSLSGARHRV
LPDRIETGTYAMAVAMAGGDVVLENTDVALLDTALETLRRAGADISATNNGMRVKRNGAGIKPVDIVTDPFPGFPTDLQA
QFMALMTRSSGISHVTETIFENRFMHVQELARLGARITLSGQTAKIEGVQRLRGAPVMATDLRASVSLVIAGLAAEGETT
VSRVYHLDRGFERLEEKLTRCGAVVERISE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=429, Percent_Identity=50.5827505827506, Blast_Score=412, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45685; Mature: 45685

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIRIVGGNELNGIIPISGAKNAALPLMIASLLTSDTLTLENVPHLADVELLMRILGNH
CCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCC
GVDVAVNGRRERQEDSYSRTIHFTCRTIVDTTASYELVSKMRASFWVIGPLLAREGHCRV
CCEEEECCCHHCCCCCCCEEEEEEEEEHHHCCHHHHHHHHHHHHHEEEEHHHCCCCCEEE
SLPGGCAIGTRPVDLFIEGLTALGATMEIDAGYINAKAPNGGLIGARYTFPKVSVGATHV
ECCCCCEECCCHHHHHHHHHHHCCCEEEECCCEEEEECCCCCEEEEEECCCCCCCCHHHH
VMMAATLARGTTVIGNAAREPEVVDLANCLNAMGAKISGAGTATITIEGVTSLSGARHRV
HHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCEECCCCEEEEEEECCCCCCCCCCCC
LPDRIETGTYAMAVAMAGGDVVLENTDVALLDTALETLRRAGADISATNNGMRVKRNGAG
CCCHHCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCC
IKPVDIVTDPFPGFPTDLQAQFMALMTRSSGISHVTETIFENRFMHVQELARLGARITLS
CCCEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEC
GQTAKIEGVQRLRGAPVMATDLRASVSLVIAGLAAEGETTVSRVYHLDRGFERLEEKLTR
CCCCHHHHHHHHCCCCEEEHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
CGAVVERISE
HHHHHHHHCC
>Mature Secondary Structure
MDRIRIVGGNELNGIIPISGAKNAALPLMIASLLTSDTLTLENVPHLADVELLMRILGNH
CCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCC
GVDVAVNGRRERQEDSYSRTIHFTCRTIVDTTASYELVSKMRASFWVIGPLLAREGHCRV
CCEEEECCCHHCCCCCCCEEEEEEEEEHHHCCHHHHHHHHHHHHHEEEEHHHCCCCCEEE
SLPGGCAIGTRPVDLFIEGLTALGATMEIDAGYINAKAPNGGLIGARYTFPKVSVGATHV
ECCCCCEECCCHHHHHHHHHHHCCCEEEECCCEEEEECCCCCEEEEEECCCCCCCCHHHH
VMMAATLARGTTVIGNAAREPEVVDLANCLNAMGAKISGAGTATITIEGVTSLSGARHRV
HHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCEECCCCEEEEEEECCCCCCCCCCCC
LPDRIETGTYAMAVAMAGGDVVLENTDVALLDTALETLRRAGADISATNNGMRVKRNGAG
CCCHHCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCC
IKPVDIVTDPFPGFPTDLQAQFMALMTRSSGISHVTETIFENRFMHVQELARLGARITLS
CCCEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEC
GQTAKIEGVQRLRGAPVMATDLRASVSLVIAGLAAEGETTVSRVYHLDRGFERLEEKLTR
CCCCHHHHHHHHCCCCEEEHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
CGAVVERISE
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA