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The map label for this gene is mcpA [H]

Identifier: 209547794

GI number: 209547794

Start: 185104

End: 187113

Strand: Reverse

Name: mcpA [H]

Synonym: Rleg2_0185

Alternate gene names: 209547794

Gene position: 187113-185104 (Counterclockwise)

Preceding gene: 209547796

Following gene: 209547792

Centisome position: 4.12

GC content: 65.92

Gene sequence:

>2010_bases
ATGTTGAAACATCTGAAAATCCGCACGAAAATCATATCGGTCGTGGCGCTCCTCGGGCTGATCACGATGGCCGGGCTGGT
CTATGTCATCGCCGAATTCCGCCGTGCGGATGCCGCCTACAGCGCCTTCATCGATCATGAAGCGATGGCCTCGATGCAGA
GCGCGCGCGCCAGCGCCTCGGTGGTGGCCTCAGTGCTGCAGGTGAGCCTGCTTGCCGACATGAAGCCGGATACGCCGGCA
TTCCAGACGACGCTCGCCACGCCGAGCAAACTGCCGCAGGCCCGCGAGCGGATGAAGGATGCGCTGGCGCTGGTGCCGAG
CCGCAAACAAGCGATCGACGAAATTCAGGCCGGCATCGATGAGATCGAAACGCTGGCGAACAAGATCATCGAGCAGAGCA
AAGCCAAGGACGGCGCCGGGGCGCAGGCGAATGTTGCCCTGATCAATGCCAAGCTCAATGCGCTGACGCCGAAGATGATC
GCCAACAATGATGCGATGATGGCGATGCTCAACGACGGCGGCGACGCGCTTTCGGCTTCGGTCAACGGGCGGATCGTCTT
CTGCCTCGTTCTGATCGGCATCGCCGTGCTCGCCGCCGTCGGCTTCAGCGTTATCGTCGCCCAGATGGGCATTGCCGGCC
CGATGACGCGGCTCAACCTGCGCATGACACGGCTTGCCGAGGGCGATACCGCAAGCGAGGTCGGCGGGCTCGACCGCGGC
GACGAAGTCGGCCAGATGGCCAAGGCCGTCTCGATCTTCCGCGACAACGCGATCGAGCGTGGCCGAATCGAGGCGCGTGC
CGAAGCCGACCGCAACCTCAGCGACGGCGAGCGCCGCGAACGCGAGGCGCAGCGGACCCGTGAAGCATCCGAACTCGAAG
GCGCCGTGACCGCACTCGGCGACGGCCTGCGCCGCCTTGCCGCCGGTGATCTCGCCTCGCATATCGACCAGCCCTTCGTC
GCCCATCTCGATGCGCTGCGCGAGGATTTCAACAATTCGGTCGAGAAGCTCAACGAGGCCCTGCATACGGTCGGCGCCAA
TGCCCGGGCGATCGGCGCCGGCGCCAACGAGATCCGCTCTTCCGCAGACGAGCTTTCCAGGCGGACGGAACAGCAGTCGG
CCTCCGTCGAAGAGACGGCGGCAGCCCTGGAAGAGATCACCACGACGGTTCGCGACGCCGCCAAGCGTGCCGAGGAGGCA
AGCCAGCTCGTCGCCCGCACCCGCCTCGGCGCCGAAAAATCCGGCGAGATCGTCCGCAAGGCCGTCTCCGCCATGCAGCA
GATCGAAAAATCCTCGGGCGAAATCTCCAACATCATCGGCGTCATCGACGACATCGCCTTCCAGACCAACCTTCTGGCCT
TGAACGCCGGCGTCGAAGCGGCGCGCGCCGGCGAAGCCGGCAAGGGCTTTGCCGTCGTTGCCCAGGAGGTGCGCGAACTC
GCCCAGCGTTCCGCCAAGGCGGCAAAGGAAATCAAGGACCTGATCACCAATTCCGGCACGCATGTGCAGACCGGCGTTTC
CCTCGTCGGCGAAACCGGCAAGGCGCTCGATTCGATCGTCCAGGAGGTGCAGGAAATCAACCAGCACGTCCACGCCATCG
CCGAAGCCTCGCGCGAACAGTCGATCGGGCTGCAGGAGATCAACACCGCCGTCAACACCATGGATCAGGGTACGCAGCAG
AACGCCGCCATGGTCGAGCAATCCACAGCCGCCAGCCACAGCCTGGCGACGGAAGCGACGGCGCTGAACAATCTGCTCGG
CCAATTCCGGCTGACCGGCACCGGCGGCTTCGCCGCTGCCGCGCCGATCTCCTCGACCCGACCGCCGGCAGCCGCCCCAC
GCGCCGCCGCGCGCCCAGTTGCCAAGGCCCCCGCGGTCCGCGTCGCCCGGGAAGGCACCGCCCGCCCAACCGCCTCACCG
GCCCGCGCCCTCAGCCAGACGCTTGCCAACGCTTTCGGTGCAACCAACAGCGCGCCGAAAGGCCAGGATGGTGACTGGAC
GGAGTTCTGA

Upstream 100 bases:

>100_bases
CAATAATCCCTGAGCCGCGACACCGACGCAGCGCTCTGTTTGCAACAATTGATTTCAAAGAACCGGGCGTGCGACGCCCG
GTCAACCGGGTAACATTTCC

Downstream 100 bases:

>100_bases
GGCACGGCCGTTCAGTTCGCGCCCGAAGCCTGCCCCTCACCCTAACCCTCTCCCCGTAAACGGGGCGAGGGGACGTGCCA
TGCGCGAGGCTAGCGAGGAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MLKHLKIRTKIISVVALLGLITMAGLVYVIAEFRRADAAYSAFIDHEAMASMQSARASASVVASVLQVSLLADMKPDTPA
FQTTLATPSKLPQARERMKDALALVPSRKQAIDEIQAGIDEIETLANKIIEQSKAKDGAGAQANVALINAKLNALTPKMI
ANNDAMMAMLNDGGDALSASVNGRIVFCLVLIGIAVLAAVGFSVIVAQMGIAGPMTRLNLRMTRLAEGDTASEVGGLDRG
DEVGQMAKAVSIFRDNAIERGRIEARAEADRNLSDGERREREAQRTREASELEGAVTALGDGLRRLAAGDLASHIDQPFV
AHLDALREDFNNSVEKLNEALHTVGANARAIGAGANEIRSSADELSRRTEQQSASVEETAAALEEITTTVRDAAKRAEEA
SQLVARTRLGAEKSGEIVRKAVSAMQQIEKSSGEISNIIGVIDDIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVREL
AQRSAKAAKEIKDLITNSGTHVQTGVSLVGETGKALDSIVQEVQEINQHVHAIAEASREQSIGLQEINTAVNTMDQGTQQ
NAAMVEQSTAASHSLATEATALNNLLGQFRLTGTGGFAAAAPISSTRPPAAAPRAAARPVAKAPAVRVAREGTARPTASP
ARALSQTLANAFGATNSAPKGQDGDWTEF

Sequences:

>Translated_669_residues
MLKHLKIRTKIISVVALLGLITMAGLVYVIAEFRRADAAYSAFIDHEAMASMQSARASASVVASVLQVSLLADMKPDTPA
FQTTLATPSKLPQARERMKDALALVPSRKQAIDEIQAGIDEIETLANKIIEQSKAKDGAGAQANVALINAKLNALTPKMI
ANNDAMMAMLNDGGDALSASVNGRIVFCLVLIGIAVLAAVGFSVIVAQMGIAGPMTRLNLRMTRLAEGDTASEVGGLDRG
DEVGQMAKAVSIFRDNAIERGRIEARAEADRNLSDGERREREAQRTREASELEGAVTALGDGLRRLAAGDLASHIDQPFV
AHLDALREDFNNSVEKLNEALHTVGANARAIGAGANEIRSSADELSRRTEQQSASVEETAAALEEITTTVRDAAKRAEEA
SQLVARTRLGAEKSGEIVRKAVSAMQQIEKSSGEISNIIGVIDDIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVREL
AQRSAKAAKEIKDLITNSGTHVQTGVSLVGETGKALDSIVQEVQEINQHVHAIAEASREQSIGLQEINTAVNTMDQGTQQ
NAAMVEQSTAASHSLATEATALNNLLGQFRLTGTGGFAAAAPISSTRPPAAAPRAAARPVAKAPAVRVAREGTARPTASP
ARALSQTLANAFGATNSAPKGQDGDWTEF
>Mature_669_residues
MLKHLKIRTKIISVVALLGLITMAGLVYVIAEFRRADAAYSAFIDHEAMASMQSARASASVVASVLQVSLLADMKPDTPA
FQTTLATPSKLPQARERMKDALALVPSRKQAIDEIQAGIDEIETLANKIIEQSKAKDGAGAQANVALINAKLNALTPKMI
ANNDAMMAMLNDGGDALSASVNGRIVFCLVLIGIAVLAAVGFSVIVAQMGIAGPMTRLNLRMTRLAEGDTASEVGGLDRG
DEVGQMAKAVSIFRDNAIERGRIEARAEADRNLSDGERREREAQRTREASELEGAVTALGDGLRRLAAGDLASHIDQPFV
AHLDALREDFNNSVEKLNEALHTVGANARAIGAGANEIRSSADELSRRTEQQSASVEETAAALEEITTTVRDAAKRAEEA
SQLVARTRLGAEKSGEIVRKAVSAMQQIEKSSGEISNIIGVIDDIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVREL
AQRSAKAAKEIKDLITNSGTHVQTGVSLVGETGKALDSIVQEVQEINQHVHAIAEASREQSIGLQEINTAVNTMDQGTQQ
NAAMVEQSTAASHSLATEATALNNLLGQFRLTGTGGFAAAAPISSTRPPAAAPRAAARPVAKAPAVRVAREGTARPTASP
ARALSQTLANAFGATNSAPKGQDGDWTEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=329, Percent_Identity=42.2492401215805, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI2367378, Length=263, Percent_Identity=46.7680608365019, Blast_Score=198, Evalue=1e-51,
Organism=Escherichia coli, GI1787690, Length=328, Percent_Identity=40.2439024390244, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1788194, Length=293, Percent_Identity=43.0034129692833, Blast_Score=189, Evalue=6e-49,
Organism=Escherichia coli, GI1789453, Length=262, Percent_Identity=37.4045801526718, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 70242; Mature: 70242

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKHLKIRTKIISVVALLGLITMAGLVYVIAEFRRADAAYSAFIDHEAMASMQSARASAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVASVLQVSLLADMKPDTPAFQTTLATPSKLPQARERMKDALALVPSRKQAIDEIQAGID
HHHHHHHHHHHHCCCCCCCHHHHHCCCHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EIETLANKIIEQSKAKDGAGAQANVALINAKLNALTPKMIANNDAMMAMLNDGGDALSAS
HHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHCCHHHHCCCCCEEEEECCCCCCEECC
VNGRIVFCLVLIGIAVLAAVGFSVIVAQMGIAGPMTRLNLRMTRLAEGDTASEVGGLDRG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCC
DEVGQMAKAVSIFRDNAIERGRIEARAEADRNLSDGERREREAQRTREASELEGAVTALG
HHHHHHHHHHHHHHHCCHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DGLRRLAAGDLASHIDQPFVAHLDALREDFNNSVEKLNEALHTVGANARAIGAGANEIRS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHH
SADELSRRTEQQSASVEETAAALEEITTTVRDAAKRAEEASQLVARTRLGAEKSGEIVRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AVSAMQQIEKSSGEISNIIGVIDDIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVREL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHH
AQRSAKAAKEIKDLITNSGTHVQTGVSLVGETGKALDSIVQEVQEINQHVHAIAEASREQ
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIGLQEINTAVNTMDQGTQQNAAMVEQSTAASHSLATEATALNNLLGQFRLTGTGGFAAA
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHC
APISSTRPPAAAPRAAARPVAKAPAVRVAREGTARPTASPARALSQTLANAFGATNSAPK
CCCCCCCCCCCCCCHHCCCHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GQDGDWTEF
CCCCCCCCC
>Mature Secondary Structure
MLKHLKIRTKIISVVALLGLITMAGLVYVIAEFRRADAAYSAFIDHEAMASMQSARASAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVASVLQVSLLADMKPDTPAFQTTLATPSKLPQARERMKDALALVPSRKQAIDEIQAGID
HHHHHHHHHHHHCCCCCCCHHHHHCCCHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EIETLANKIIEQSKAKDGAGAQANVALINAKLNALTPKMIANNDAMMAMLNDGGDALSAS
HHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHCCHHHHCCCCCEEEEECCCCCCEECC
VNGRIVFCLVLIGIAVLAAVGFSVIVAQMGIAGPMTRLNLRMTRLAEGDTASEVGGLDRG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCC
DEVGQMAKAVSIFRDNAIERGRIEARAEADRNLSDGERREREAQRTREASELEGAVTALG
HHHHHHHHHHHHHHHCCHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DGLRRLAAGDLASHIDQPFVAHLDALREDFNNSVEKLNEALHTVGANARAIGAGANEIRS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHH
SADELSRRTEQQSASVEETAAALEEITTTVRDAAKRAEEASQLVARTRLGAEKSGEIVRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AVSAMQQIEKSSGEISNIIGVIDDIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVREL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHH
AQRSAKAAKEIKDLITNSGTHVQTGVSLVGETGKALDSIVQEVQEINQHVHAIAEASREQ
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIGLQEINTAVNTMDQGTQQNAAMVEQSTAASHSLATEATALNNLLGQFRLTGTGGFAAA
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHC
APISSTRPPAAAPRAAARPVAKAPAVRVAREGTARPTASPARALSQTLANAFGATNSAPK
CCCCCCCCCCCCCCHHCCCHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GQDGDWTEF
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]